Chronic liver iron overload in the baboon by ferric nitrilotriacetate. Morphologic and functional changes with special reference to collagen synthesis enzymes.

abstract：:Hepatocellular carcinoma (HCC) arises from a number of cirrhosis-related and non-cirrhosis-related exposures and is one of the leading causes of cancer-related deaths worldwide. Achieving a durable cure currently relies on either resection or transplantation, but since most patients will be diagnosed with inoperable d...

journal_title：Digestive diseases and sciences

authors： Saffo S,Taddei TH

更新日期：2019-04-01 00:00:00

abstract：:Bicyclol is a synthetic antihepatitis drug with antioxidative property. The present study was performed to investigate the effect of bicyclol on liver regeneration after partial hepatectomy in rats. Bicyclol (300 mg/kg) was given to rats subjected to 70% hepatectomy three times before operation. At 6, 24, and 48 h aft...

journal_title：Digestive diseases and sciences

authors： Yao XM,Zhao J,Li Y,Li Y

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Mucosal addressin cell adhesion molecule-1 (MAdCAM-1), a member of the immunoglobulin superfamily, is essential for gut-specific homing of leukocytes; however, it has not been well characterized in rhesus macaques. AIMS:To obtain the complete nucleotide sequence of rhesus macaque MAdCAM-1 cDNA and determine...

journal_title：Digestive diseases and sciences

authors： Wang Y,Yao WR,Duan JZ,Xu W,Yang GB

更新日期：2014-10-01 00:00:00

abstract：:In our hospital within one year two patients with Crohn's disease were seen who developed an acute myelocytic leukemia. A review of the literature reveals eight previously reported patients with both Crohn's disease and leukemia. Six of the reported 10 patients have had acute myelocytic leukemia and, interestingly, th...

journal_title：Digestive diseases and sciences

authors： Halme L,von Knorring J,Elonen E

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND:Gastric acidification inhibits motilin-induced gastric phase III contractions. However, the underlying mechanism has not been thoroughly investigated. Here, we studied the inhibitory mechanism by gastric acidification on motilin-induced contraction in Suncus murinus (S. murinus). METHODS:We measured interdi...

journal_title：Digestive diseases and sciences

authors： Yoshimura M,Mikami T,Kuroda K,Nishida M,Ito K,Mondal A,Koyama K,Jogahara T,Sakata I,Sakai T

更新日期：2016-06-01 00:00:00

abstract：:The aim of the study was to assess the value of quantitative attenuation values (Hounsfield units) and of gallstone pattern by computerized tomography in predicting response to bile acid therapy. We carried out a prospective study in a multicenter setting on 90 consecutive outpatients with radiolucent gallstones. All ...

journal_title：Digestive diseases and sciences

authors： Petroni ML,Jazrawi RP,Grundy A,Lanzini A,Pigozzi MG,Biasio A,Heaton KW,Virjee J,Northfield TC

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Polymerase chain reaction (PCR) assays are the standard for detecting hepatitis C virus viremia. The transcription-mediated amplification (TMA)-based assay is more sensitive. METHODS:We retrospectively reviewed the charts of patients with a post-end of treatment (EOT) PCR-/TMA+ result to assess the clinical...

journal_title：Digestive diseases and sciences

authors： Thadani A,Harley J,Rubin J,Lebovics E

更新日期：2012-01-01 00:00:00

abstract：:Segments of rat ileum and colon were infused in vivo to test if 0.1 M lactate, 10(-4) M H+, or both altered mucosal structure and function. In the first series of experiments, lactate concentration was kept at 0.1 M while H+ was varied from 10(-4) to 10(-7) M. Lactate and 10(-4) M H+ in the colon, and lactate and 10(-...

journal_title：Digestive diseases and sciences

authors： Saunders DR,Sillery J

更新日期：1982-01-01 00:00:00

abstract：:This study investigates whether topical prostaglandins protect isolated gastric mucosa against injury provoked by acidified "barrier-breaking" agents. Intracellular pH (pHi), apical cell membrane potential (Vcm) and intraepithelial resistances in isolated Necturus antral mucosa were measured using double-barreled liqu...

journal_title：Digestive diseases and sciences

authors： Ranta-Knuuttila T,Mustonen H,Kivilaakso E

更新日期：2000-01-01 00:00:00

abstract：:Acetic acid-induced pan colitis in rats leads not only to colonic injury but also to a bystander ileal injury, characterized by decreased fluid and electrolyte absorption without associated histological injury or infiltration of inflammatory cells. To examine the nature of this decreased ileal fluid and electrolyte ab...

journal_title：Digestive diseases and sciences

authors： Cui N,Madsen KL,Friend DR,Stevenson BR,Fedorak RN

更新日期：1996-02-01 00:00:00

abstract：:The optimal administration of immunosuppressants such as tacrolimus (Tac) for small-for-size (SFS) grafts, where the functional liver mass is small and must regenerate, has not been reported so far. The aim of this study is to clarify the characteristics of Tac metabolism according to liver volume. Seven-week-old male...

journal_title：Digestive diseases and sciences

authors： Morine Y,Shimada M,Torii M,Imura S,Ikegami T,Kanemura H,Arakawa Y,Hanaoka J,Kanamoto M,Nii A,Yamazaki N

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Gastric intestinal metaplasia (GIM) is an accepted pathologic precursor to gastric adenocarcinoma (GAC). While surveillance of GIM in Europe and Asia is common, only limited recommendations related to endoscopic surveillance of GIM exist in the United States. AIM:To understand the clinical practice patterns...

journal_title：Digestive diseases and sciences

authors： Vance RB Jr,Kubiliun N,Dunbar KB

更新日期：2016-07-01 00:00:00

abstract：:Nonalcoholic steatohepatitis is the fastest-growing indication for the liver transplant and a leading cause of hepatocellular carcinoma among patients listed for liver transplantation in the USA. Post-transplant nonalcoholic hepatic steatosis and steatohepatitis are frequent complications of liver transplantation. Non...

journal_title：Digestive diseases and sciences

authors： Samji NS,Verma R,Keri KC,Singal AK,Ahmed A,Rinella M,Bernstein D,Abdelmalek MF,Satapathy SK

更新日期：2019-12-01 00:00:00

abstract：:In the early 1970s an increased prevalence of gallstones was reported in adults and children with immunoglobulin deficiency. As the advent of ultrasonography has largely changed the diagnostic approach to gallstones, we have reevaluated the prevalence of cholelithiasis in a group including 37 patients with common vari...

journal_title：Digestive diseases and sciences

authors： De Santis A,Paganelli R,Stefanoni R,Di Sabatino A,Angelico M

更新日期：1990-06-01 00:00:00

abstract：:Our goal was to determine whether Seirogan, an herbal medicine used as an antidiarrheal agent, modifies colonic function, including motility. Experiments were performed on four female Yucatan mini-pigs with established permanent cecal fistulas providing direct access to the colon. Long-term recordings of proximal colo...

journal_title：Digestive diseases and sciences

authors： Kuge T,Venkova K,Greenwood-Van Meerveld B

更新日期：2002-12-01 00:00:00

abstract：:A new technique for the long-term ambulatory detection of enterogastric and nonacid gastroesophageal reflux has been conceived, developed, and validated. It is based on the use of a fiberoptic sensor that utilizes the optical properties of bile. In vitro studies have shown good precision, good stability, sensitivity o...

journal_title：Digestive diseases and sciences

authors： Bechi P,Pucciani F,Baldini F,Cosi F,Falciai R,Mazzanti R,Castagnoli A,Passeri A,Boscherini S

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:Small bowel mass lesions (SBML) are a relatively common cause of obscure gastrointestinal bleeding (OGIB). Their detection has been limited by the inability to endoscopically examine the entire small intestine. This has changed with the introduction of capsule endoscopy (CE) and double balloon enteroscopy (D...

journal_title：Digestive diseases and sciences

authors： Ross A,Mehdizadeh S,Tokar J,Leighton JA,Kamal A,Chen A,Schembre D,Chen G,Binmoeller K,Kozarek R,Waxman I,Dye C,Gerson L,Harrison ME,Haluszka O,Lo S,Semrad C

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Tyrosine phosphorylation and dephosphorylation by protein tyrosine kinases and phosphatases (PTPs), respectively, play crucial roles in cellular signal transduction. Protein phosphatase non-receptor type 11 (PTPN11) is a positive signaling PTP that activates RAS and ERK signaling. Also, the PTPN11 binds with...

journal_title：Digestive diseases and sciences

authors： Kim JS,Shin OR,Kim HK,Cho YS,An CH,Lim KW,Kim SS

更新日期：2010-06-01 00:00:00

abstract：:The purpose of this study was to establish if estrogen-induced hepatocyte proliferation in vitro involves the cell cycle regulators cyclin D1, p21(Cip1), and p27(Kip1). Male rat hepatocytes were cultured in presence of 17-beta-estradiol (E2) +/- ICI-182780, a pure estrogen antagonist, and [3H]-thymidine, as required. ...

journal_title：Digestive diseases and sciences

authors： Barone M,Ladisa R,Di Leo A,Spano D,Francioso D,Aglio V,Amoruso A,Francavilla A,Iolascon A

更新日期：2006-03-01 00:00:00

abstract：:The paraoxonase (PON) genes family maps to chromosome 7q21-q22, within a loci that also showed evidence of susceptibility genes for both Crohn's disease (CD) and ulcerative colitis (UC). In this case-control study we investigated the possible relationship between PON1 and PON2 polymorphisms and the risk of inflammator...

journal_title：Digestive diseases and sciences

authors： Karban A,Hartman C,Eliakim R,Waterman M,Nesher S,Barnett-Griness O,Shamir R

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Patients with cirrhosis are at high readmission risk. Using a large statewide database, we evaluated the effect of hospital cirrhosis-related patient volume on 30-day readmissions in patients with cirrhosis. METHODS:We conducted a retrospective study of the Healthcare Cost and Utilization Project State Inpa...

journal_title：Digestive diseases and sciences

authors： Wei M,Ford J,Li Q,Jeong D,Kwong AJ,Nguyen MH,Chang MS

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:We have reported previously that Candida albicans is involved in the pathogenesis of peptic ulcer perforation; it was shown that C. albicans aggravated the severity of duodenal ulceration and increased the rate of perforation. We considered it incumbent upon us to ascertain whether C. albicans is a virulence...

journal_title：Digestive diseases and sciences

authors： Nakamura T,Yoshida M,Kitagawa Y,Jin L,Ishikawa H,Kameyama K,Wakabayashi G,Tanabe M,Kawachi S,Shinoda M,Saikawa Y,Wada N,Kubota T,Kumai K,Sano K,Kitajima M

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:A new device with metallic wires for scrape cytology was developed. AIMS:To compare the diagnostic performance of scrape cytology and conventional cytology during endoscopic retrograde cholangiopancreatography for biliary strictures. METHODS:A total of 420 cases with biliary stricture underwent transpapill...

journal_title：Digestive diseases and sciences

authors： Nakahara K,Michikawa Y,Morita R,Suetani K,Morita N,Sato J,Tsuji K,Ikeda H,Matsunaga K,Watanabe T,Matsumoto N,Kobayashi S,Otsubo T,Itoh F

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Ectopic expression of gastric intrinsic factor (IF) has been described in rodent models of chronic gastritis. AIMS:The current study undertook to determine if ectopic IF was also present in chronic gastritis in humans and might identify the process of ectopic protein expression as part of the response to ch...

journal_title：Digestive diseases and sciences

authors： Shao JS,Carmel R,Alpers DH

更新日期：2011-11-01 00:00:00

abstract：:Bacterial infection remains a leading cause of mortality and morbidity for patients with cirrhosis, with hospitalization, alterations in the intestinal microbiota, and therapeutic drugs all implicated in its development. Bacterial infections also remain the most common precipitant of acute-on-chronic liver failure, wi...

journal_title：Digestive diseases and sciences

authors： Cannon MD,Martin P,Carrion AF

更新日期：2020-01-01 00:00:00

abstract：:Esophageal diverticula can cause significant symptoms and affect the quality of life. There has been recent interest in the use of peroral endoscopic myotomy in the management of esophageal diverticula (D-POEM). In this meta-analysis, we have evaluated the efficacy and safety of D-POEM in the management of esophageal ...

journal_title：Digestive diseases and sciences

authors： Kamal F,Khan MA,Lee-Smith W,Sharma S,Marella HK,Iqbal U,Mcdonough S,Aslam A,Ismail MK,Tombazzi C,Adler DG

更新日期：2020-10-29 00:00:00

abstract：:The possibility of obtaining oral desensitization in patients with food allergy is still a matter of debate. We decided to evaluate the safety and efficacy of standardized protocols for oral desensitization with the most common food allergens. Forty-two children (ages up to 16 years) diagnosed as affected by food alle...

journal_title：Digestive diseases and sciences

authors： Patriarca G,Nucera E,Pollastrini E,Roncallo C,De Pasquale T,Lombardo C,Pedone C,Gasbarrini G,Buonomo A,Schiavino D

更新日期：2007-07-01 00:00:00

abstract：:The purpose of this study was to use simultaneous anal manometry and high-frequency endoluminal ultrasonography (EUS) to determine the relationship between resting anal pressure and cross-sectional area of the internal and external anal sphincters. Eleven normal subjects underwent simultaneous anal EUS and manometry u...

journal_title：Digestive diseases and sciences

authors： Wong RF,Bonapace ES Jr,Chung CY,Liu JB,Parkman HP,Miller LS

更新日期：1998-11-01 00:00:00

abstract：:Selected aspects of bile acid metabolism were assessed in six women with primary biliary cirrhosis and varying degrees of cholestasis. Urinary bile acid excretion was markedly increased and correlated highly with serum levels. In three patients in whom urinary bile acids were separated by chromatography, the majority ...

journal_title：Digestive diseases and sciences

authors： Raedsch R,Lauterburg BH,Hofmann AF

更新日期：1981-05-01 00:00:00

abstract：:This paper reports the results of a multicenter prospective study of 188 consecutive patients affected by gastric ulcer, verified by endoscopy, in whom the frequency of a mycotic infection of the lesion was evaluated as well as the eventual influence of such pathology on the efficiency of medical treatment, the healin...

journal_title：Digestive diseases and sciences

authors： Di Febo G,Miglioli M,Calò G,Biasco G,Luzza F,Gizzi G,Cipollini F,Rossi A,Barbara L

更新日期：1985-02-01 00:00:00