Bacterial translocation to mesenteric lymph nodes increases in chronic portal hypertensive rats.

abstract：BACKGROUND:Diabetic gastroparesis is a common complication of diabetes mellitus, which mainly affects women. Previous studies have demonstrated that oxidative stress is involved in its onset and development. AIMS:This study evaluated the role of vitamin C on diabetes-associated gastric dysmotility. METHODS:Female rat...

journal_title：Digestive diseases and sciences

authors： Da Silva LM,da Silva RCMVAF,Maria-Ferreira D,Beltrame OC,da Silva-Santos JE,Werner MFP

更新日期：2017-09-01 00:00:00

abstract：:Selected aspects of bile acid metabolism were assessed in six women with primary biliary cirrhosis and varying degrees of cholestasis. Urinary bile acid excretion was markedly increased and correlated highly with serum levels. In three patients in whom urinary bile acids were separated by chromatography, the majority ...

journal_title：Digestive diseases and sciences

authors： Raedsch R,Lauterburg BH,Hofmann AF

更新日期：1981-05-01 00:00:00

abstract：:Irritable bowel syndrome is a frequent gastrointestinal disorder of unknown etiology. The serotonin transporter regulates the intensity and duration of serotonin signaling in the gut and is, therefore, an attractive candidate gene for irritable bowel syndrome. Previous studies investigating the 5-HTTLPR and Stin2 VNTR...

journal_title：Digestive diseases and sciences

authors： Kohen R,Jarrett ME,Cain KC,Jun SE,Navaja GP,Symonds S,Heitkemper MM

更新日期：2009-12-01 00:00:00

abstract：:The aim of this study was to review the impact of infliximab therapy on children with treatment-resistant Crohn's disease. Treatment resistance was defined as clinically active disease despite >4 months of immunosuppressive therapy. The outcome variables were time to first remission, duration of remission and the need...

journal_title：Digestive diseases and sciences

authors： Afzal NA,Ozzard A,Keady S,Thomson M,Murch S,Heuschkel R

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:In search for a source of gastrointestinal bleeding, endoscopy frequently reveals mucosal lesions of questionable dignity. AIM:To investigate the probability of ascertaining conclusive evidence for gastrointestinal bleeding from a suspicious mucosal lesion through a single or multiple consecutive endoscopie...

journal_title：Digestive diseases and sciences

authors： Sonnenberg A

更新日期：2013-05-01 00:00:00

abstract：:The effect of 5-hydroxytryptamine (5HT) was studied in circular and longitudinal muscle from the proximal and distal colon of New Zealand white rabbits. 5HT stimulated a dose-dependent isometric contraction of distal and proximal circular muscle that was greater than in distal longitudinal muscle (P less than 0.01). 5...

journal_title：Digestive diseases and sciences

authors： Ng WW,Jing J,Hyman PE,Snape WJ Jr

更新日期：1991-02-01 00:00:00

abstract：:The effect of ursodeoxycholic acid (UDCA) on bile lipid composition and bile acid kinetics was evaluated in seven cholesterol gallstone patients following one month of UDCA administration (12 mg/kg/day). UDCA administration induces a significant reduction in the cholesterol saturation index (SI). After UDCA treatment,...

journal_title：Digestive diseases and sciences

authors： Roda E,Roda A,Sama C,Festi D,Mazzella G,Aldini R,Barbara L

更新日期：1979-02-01 00:00:00

abstract：:We have used double-contrast radiographic techniques to clarify what changes in the configuration and movements of the gastroduodenal junction result when peptic lesions involve the distal gastric segment between the proximal (PPL) and the distal pyloric muscle loop (DPL). Among 50 cases of pyloric ulceration diagnose...

journal_title：Digestive diseases and sciences

authors： Lu CC,Schulze-Delrieu K

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND:Gastrointestinal motility disorder is an important pathological basis for functional dyspepsia (FD). Epigastric ache and discomfort are the main symptoms of FD, and ghrelin deficiency is closely related to the occurrence and development of FD. While electroacupuncture (EA) alleviated the symptoms of FD patie...

journal_title：Digestive diseases and sciences

authors： Tang L,Zeng Y,Li L,Wang J,Peng D,Zhang T,Zhang H,An X

更新日期：2020-06-01 00:00:00

abstract：:To determine if organic anions contribute to the diarrhea of inflammatory bowel disease, we measured osmolality, electrolytes, short-chain fatty acids, lactic acid, and some Krebs cycle anions in 24-hr fecal collections from 18 patients with chronic ulcerative colitis, 20 with Crohn's disease of the colon, and 16 norm...

journal_title：Digestive diseases and sciences

authors： Vernia P,Gnaedinger A,Hauck W,Breuer RI

更新日期：1988-11-01 00:00:00

abstract：:Gallbladder contractility has been studied in 21 obese patients (greater than 130% ideal weight) and 30 nonobese subjects before and at regular intervals after the administration of a regular solid-liquid meal, and after a low-calorie, low-fat meal used conventionally for weight-loss purposes (Modifast). Gallbladder v...

journal_title：Digestive diseases and sciences

authors： Marzio L,Capone F,Neri M,Mezzetti A,De Angelis C,Cuccurullo F

更新日期：1988-01-01 00:00:00

abstract：:The interaction of [35S]methionine with hepatic tRNA in normal, carcinogen-treated, and partially hepatectomized rats was studied. tRNA was preferentially labeled following [35S]methionine (1.6 mCi, 25 mg/kg body wt) administration by intraperitoneal injection. The extent of [35S]methionine-tRNA interaction was impair...

journal_title：Digestive diseases and sciences

authors： Kanduc D,Quagliariello E

更新日期：1991-07-01 00:00:00

abstract：:The effect of inhibition of acid secretion on parietal cell morphology and the concentration of H,K-ATPase alpha-subunit protein was determined by electron microscopy and western blotting. Omeprazole or famotidine alone or in combination were used. Control animals showed a morphological stimulation index (0 = resting,...

journal_title：Digestive diseases and sciences

authors： Scott DR,Besancon M,Sachs G,Helander H

更新日期：1994-10-01 00:00:00

abstract：:Forty-one (98%) of 42 patients with achalasia of the esophagus had pneumatic dilatation performed successfully using the Brown-McHardy dilator. One to four dilatations (mean, 1.9) were done on each patient with inflation pressures of 8-15 psi (mean, 11.1 psi). Immediately after the procedure, all patients were examine...

journal_title：Digestive diseases and sciences

authors： Ott DJ,Richter JE,Wu WC,Chen YM,Castell DO,Gelfand DW

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND:Eosinophilic esophagitis (EoE) is associated with tissue remodeling that can result in esophageal mucosal fragility, and esophageal dilation for patients with EoE is known to cause painful mucosal lacerations. Clinicians have been admonished that patients with EoE may be exceptionally predisposed to perforat...

journal_title：Digestive diseases and sciences

authors： Jacobs JW Jr,Spechler SJ

更新日期：2010-06-01 00:00:00

abstract：:Not much is known about the relationship between portal hemodynamics and the grades of cirrhosis. Using pulsed Doppler ultrasonography, we studied portal vein diameter, portal flow velocity, and portal blood flow rate in 37 patients with liver cirrhosis (11 Child's A, 13 Child's B, and 13 Child's C) and 10 healthy con...

journal_title：Digestive diseases and sciences

authors： Chawla Y,Santa N,Dhiman RK,Dilawari JB

更新日期：1998-02-01 00:00:00

abstract：:This study compared women with irritable bowel syndrome who had a history of an anxiety or depressive disorder to those without symptoms of either disorder on indicators of cardiac parasympathetic activity, autonomic nervous system balance, and general autonomic activity. The Diagnostic Interview Schedule was used to ...

journal_title：Digestive diseases and sciences

authors： Jarrett ME,Burr RL,Cain KC,Hertig V,Weisman P,Heitkemper MM

更新日期：2003-02-01 00:00:00

abstract：:An intravenous injection of diphenylthiocarbazone (dithizone), a zinc chelator, induces selective killing and rapid regeneration of Paneth cells, which have a large amount of zinc in their cytoplasmic granules. We examined the expression pattern of transforming growth factor (TGF) -alpha and TGF-beta1 in this regenera...

journal_title：Digestive diseases and sciences

authors： Seno H,Sawada M,Fukuzawa H,Morita Y,Takaishi S,Hiai H,Chiba T

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND AND AIM:There is no consensus regarding the benefit of eradicating Helicobacter pylori (H. pylori) infection in patients with functional dyspepsia (FD). We intended to compare the symptom response to H. pylori eradication in FD patients in presence or absence of microscopic duodenitis (MD). METHODS:Patients...

journal_title：Digestive diseases and sciences

authors： Mirbagheri SS,Mirbagheri SA,Nabavizadeh B,Entezari P,Ostovaneh MR,Hosseini SM,Rakhshani N,Safa H

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Acute variceal bleeding (AVB) in patients with cirrhosis is associated with high mortality, ranging from 12 to 20% at 6 weeks. The existing prognostic models for AVB lack precision and require further validation. AIM:In this prospective study, we aimed to develop and validate a new prognostic model for AVB,...

journal_title：Digestive diseases and sciences

authors： Rout G,Sharma S,Gunjan D,Kedia S,Saraya A,Nayak B,Singh V,Kumar R,Shalimar

更新日期：2019-08-01 00:00:00

abstract：:Possible differences in the abilities of esophageal body and lower esophageal sphincter muscles to utilize substrates to support agonist-induced contractions were studied. Strips of longitudinal, circular, and lower esophageal sphincter muscle from the opossum esophagus were first contracted to approximately 70% of th...

journal_title：Digestive diseases and sciences

authors： Percy WH,Sutherland J,Christensen J

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Hepatic encephalopathy is a syndrome whose physiopathology is poorly understood; therefore, current diagnostic tests are imperfect and modern therapy is nonspecific. Particularly, it has been suggested that inflammation plays an important role in the pathogenesis of portal hypertensive encephalopathy in the ...

journal_title：Digestive diseases and sciences

authors： Merino J,Aller MA,Rubio S,Arias N,Nava MP,Loscertales M,Arias J,Arias JL

更新日期：2011-08-01 00:00:00

abstract：:The present study aimed to clarify the endoscopic ultrasonography (EUS) features of nonneoplastic (cholesterol polyps and adenomyomatosis) and neoplastic (adenoma and adenocarcinoma) gallbladder polyps and to evaluate the effectiveness and limitation of EUS in the differential diagnosis of these lesions. We retrospect...

journal_title：Digestive diseases and sciences

authors： Akatsu T,Aiura K,Shimazu M,Ueda M,Wakabayashi G,Tanabe M,Kawachi S,Kitajima M

更新日期：2006-02-01 00:00:00

abstract：:The article "Characterization of Creatine Kinase Levels in Tofacitinib-Treated Patients with Ulcerative Colitis: Results from Clinical Trials", written by Remo Panaccione, John D. Isaacs, Lea Ann Chen, Wenjin Wang, Amy Marren, Kenneth Kwok, Lisy Wang, Gary Chan and Chinyu Su, was originally published electronically on...

journal_title：Digestive diseases and sciences

authors： Panaccione R,Isaacs JD,Chen LA,Wang W,Marren A,Kwok K,Wang L,Chan G,Su C

更新日期：2020-10-10 00:00:00

abstract：:The present study aimed to investigate the role of nitric oxide on the oxidative damage in isolated rabbit gastric cells exposed to hypoxia-reoxygenation. Nitric oxide synthesis modulators such as L-arginine and NG-nitro-L-arginine methyl ester, a nitric oxide donor, sodium nitroprusside, and superoxide dismutase were...

journal_title：Digestive diseases and sciences

authors： Kim H,Kim KH

更新日期：1998-05-01 00:00:00

abstract：:Zinc is an essential trace element, exerting important antioxidant, anti-inflammatory, and antiapoptotic effects. It affects growth and development and participates in processes such as aging and cancer induction. The liver is important for the regulation of zinc homeostasis, while zinc is necessary for proper liver f...

journal_title：Digestive diseases and sciences

authors： Stamoulis I,Kouraklis G,Theocharis S

更新日期：2007-07-01 00:00:00

abstract：:Inhibitors of gastric acid secretion are efficient drugs in the treatment of acid-related diseases. However, by reducing gastric acidity, hypergastrinemia develops. Gastrin regulates its target cell, the enterochromaffin (ECL) cell, both functionally and tropicaly. Long-term hypergastrinemia in whatever species studie...

journal_title：Digestive diseases and sciences

authors： Waldum HL,Gustafsson B,Fossmark R,Qvigstad G

更新日期：2005-10-01 00:00:00

abstract：AIM:To investigate whether a diagnostic delay is associated with a poor outcome in Crohn's disease (CD). METHODS:Medical and socioeconomic characteristics as well as medications and need for surgery of consecutive CD adults patients followed in three referral centers were prospectively recorded using an electronic dat...

journal_title：Digestive diseases and sciences

authors： Nahon S,Lahmek P,Paupard T,Lesgourgues B,Chaussade S,Peyrin-Biroulet L,Abitbol V

更新日期：2016-11-01 00:00:00

abstract：:During topical dissolution of gallstones, solvent can escape to the duodenum causing toxic effects that have not yet been adequately quantified. We compared the local intestinal cytotoxic and systemic hepatotoxic effects of two gallstone solvents, methyl tert-butyl ether and ethyl propionate, on the rabbit's duodenum....

journal_title：Digestive diseases and sciences

authors： Clerici C,Gentili G,Zakko SF,Balò S,Miglietti M,Giansanti M,Modesto R,Guttermuth CF,Morelli A

更新日期：1997-03-01 00:00:00

abstract：:The purpose of this study was to investigate interdigestive cycling and postprandial release of pancreatic polypeptide (PP) in relation to exocrine pancreatic function in chronic pancreatitis (CP). We investigated nine patients with mild-moderate CP (MCP), eight patients with severe CP and steathorrea (SCP), and 17 he...

journal_title：Digestive diseases and sciences

authors： Pieramico O,Nelson DK,Glasbrenner B,Malfertheiner P

更新日期：1994-01-01 00:00:00