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Baseline hypoxemia as a prognostic marker for pulmonary complications and outcome in patients with acute pancreatitis.

Abstract：

:The purpose of the present study was to investigate the prognostic role of severe hypoxemia on admission as an independent risk factor of pulmonary complications and mortality in patients with acute pancreatitis. Pulmonary complications were studied in 166 previously healthy patients with acute pancreatitis. Forty-eight patients (28.9%) developed one or more pulmonary complications, including pleural effusion, atelectasis, pulmonary consolidations, and acute respiratory distress syndrome (ARDS). Pulmonary consolidations (odds ratio = 7.25) and, especially, ARDS (odds ratio = 22.9) were significantly associated with severe baseline hypoxemia (PaO2, <60 mm Hg). Mortality was mainly related to severity of disease (odds ratio = 46.45), while hypoxemia was also found to be an independent risk factor of poor outcome (odds ratio = 9.56). It seems that, in patients with acute pancreatitis, severe hypoxemia on admission may be an early predictive marker of pulmonary complications, especially ARDS, and, independently of severity score, it may also be a marker of poor outcome.

journal_name

Dig Dis Sci

journal_title

Digestive diseases and sciences

authors

Polyzogopoulou E,Bikas C,Danikas D,Koutras A,Kalfarentzos F,Gogos CA

doi

10.1023/b:ddas.0000011617.00308.e3

subject

Has Abstract

pub_date

2004-01-01 00:00:00

pages

150-4

issue

1

eissn

0163-2116

issn

1573-2568

journal_volume

49

pub_type

杂志文章

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