WDR34 Activates Wnt/Beta-Catenin Signaling in Hepatocellular Carcinoma.

abstract：BACKGROUND:Gut inflammation is prevalent in chronic kidney disease (CKD) and likely contributes to systemic inflammation via disruption of the epithelial tight junction with subsequent endotoxin and bacterial translocation. AIMS:To study the expression profile of inflammatory and tight junction proteins in the colon f...

journal_title：Digestive diseases and sciences

authors： Lau WL,Liu SM,Pahlevan S,Yuan J,Khazaeli M,Ni Z,Chan JY,Vaziri ND

更新日期：2015-05-01 00:00:00

abstract：:The aim of this state-of-the-art narrative review is to evaluate the current evidence about the effectiveness of yoga as therapy for IBS and explore its potential mechanisms of action. The current literature suggests yoga is effective and safe and may target multiple mechanisms involved in treatment of IBS. Evidence f...

journal_title：Digestive diseases and sciences

authors： D'Silva A,MacQueen G,Nasser Y,Taylor LM,Vallance JK,Raman M

更新日期：2020-09-01 00:00:00

abstract：:Undernutrition is considered to have a central role in the pathogenesis of growth retardation in Crohn's disease. This may occur as a consequence of inadequate food intake, increased energy expenditure, or both. Ten growing adolescents with inactive Crohn's disease were assessed with respect to anthropometric paramete...

journal_title：Digestive diseases and sciences

authors： Zoli G,Katelaris PH,Garrow J,Gasbarrini G,Farthing MJ

更新日期：1996-09-01 00:00:00

abstract：:The purpose of this study was to evaluate the inhibitory activity of selenium-enriched probiotics against pathogenic Escherichia coli (E. coli) in vitro and in vivo. Escherichia coli was co-cultured in vitro with each probiotic strain individually, and a mixture of the four strains and its population was counted at va...

journal_title：Digestive diseases and sciences

authors： Yang J,Huang K,Qin S,Wu X,Zhao Z,Chen F

更新日期：2009-02-01 00:00:00

abstract：:Idiopathic chronic constipation has been correlated to neural abnormalities that consist of a reduced number of myenteric plexus neurons and a decreased concentration of VIP-positive nerve fibers within the circular muscle. Recent studies hypothesized the involvement of nitric oxide in motility disorders of the human ...

journal_title：Digestive diseases and sciences

authors： Cortesini C,Cianchi F,Infantino A,Lise M

更新日期：1995-11-01 00:00:00

abstract：:To study the clinicopathologic features of hepatitis C viremic patients negative for hepatitis C antibodies (anti-HCV) by current second-generation assay, we categorized 139 consecutive histologically verified patients with chronic non-A, non-B hepatitis into three groups: 121 (87%) were positive for second-generation...

journal_title：Digestive diseases and sciences

authors： Kao JH,Lai MY,Hwang YT,Yang PM,Chen PJ,Sheu JC,Wang TH,Hsu HC,Chen DS

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Diagnosis of pediatric inflammatory bowel diseases (IBD) remains challenging. We aimed at the value of immunohistochemical assessment of CD30+ lymphocytes in the intestinal mucosa in differential diagnosis between pediatric Crohn's disease (CD) and ulcerative colitis (UC) and its utility as a predictor of fu...

journal_title：Digestive diseases and sciences

authors： Fabian O,Hradsky O,Drskova T,Mikus F,Zamecnik J,Bronsky J

更新日期：2018-07-01 00:00:00

abstract：AIM:Intestinal ischemia reperfusion (IR) causes tissue injury in two ways, starting a pro-inflammatory cascade and oxidative stress. The aim of this study was to investigate the possible protective effects of caffeic acid phenethyl ester (CAPE), which has antioxidant and anti-inflammatory properties, against intestinal...

journal_title：Digestive diseases and sciences

authors： Yildiz Y,Serter M,Ek RO,Ergin K,Cecen S,Demir EM,Yenisey C

更新日期：2009-04-01 00:00:00

abstract：:To investigate the pathophysiological basis of Courvoisier's law, the gallbladder size and pliability were measured in chronic calculous cholecystitis with (7 patients) or without (25 patients) common duct obstruction, in periampullary malignancy (6 patients), and in the normal state (3 patients). The duration and lev...

journal_title：Digestive diseases and sciences

authors： Chung RS

更新日期：1983-01-01 00:00:00

abstract：:Free radical damage in reflux esophagitis of rats induced by 24-hr duodenojejunal ligation was studied. Oxygen free radicals were selectively blocked. Groups were: sham operation, reflux, reflux + superoxide dismutase (SOD), catalase, dimethylthiourea, allopurinol, and inactivated SOD or inactivated catalase alone or ...

journal_title：Digestive diseases and sciences

authors： Wetscher GJ,Hinder PR,Bagchi D,Perdikis G,Redmond EJ,Glaser K,Adrian TE,Hinder RA

更新日期：1995-06-01 00:00:00

abstract：:Factors and mechanisms involved in esophageal mucosal injury and repair are not well known. The aim of this study was to assess the effects of growth factors and prostaglandins on esophageal mucosal cell repair activities. Rabbit esophageal cells were isolated, cultured, and exposed to different growth factors and pro...

journal_title：Digestive diseases and sciences

authors： Jimenez P,Lanas A,Piazuelo E,Esteva F

更新日期：1998-10-01 00:00:00

abstract：:Ceramide plays an important role in regulating cell proliferation and apoptosis. Recent studies indicate that generation of ceramide in the intestine from sphingomyelin hydrolysis may be implicated in colon cancer development. The enzymes that catalyze the further hydrolysis of ceramide in the intestine have, however,...

journal_title：Digestive diseases and sciences

authors： Lundgren P,Nilsson A,Duan RD

更新日期：2001-04-01 00:00:00

abstract：:As infection influences the pathogenesis and presentation of celiac disease, we investigated the expression of natural antibiotics in this condition. Twenty-three adults were prospectively studied: 10 controls and 13 subjects with untreated celiac disease. Distal duodenal biopsies were taken at baseline and after 6 mo...

journal_title：Digestive diseases and sciences

authors： Taha AS,Faccenda E,Angerson WJ,Balsitis M,Kelly RW

更新日期：2005-04-01 00:00:00

abstract：:Our purpose was to evaluate the relationship between the clinical and histological features in a cohort of patients who had gastroesophageal reflux-related lesions diagnosed after upper digestive endoscopy. In all, 589 patients scheduled for elective endoscopy in a multicentric prospective study were evaluated. Multip...

journal_title：Digestive diseases and sciences

authors： Aste H,Bonelli L,Ferraris R,Conio M,Lapertosa G

更新日期：1999-12-01 00:00:00

abstract：:Isosmotic liquid peptone meals adjusted to pH 7, 3, and 1.5 were instilled on separate days into the stomachs of 8 duodenal ulcer patients and 7 healthy controls. Using a marker-dilution method, duodenal acid load (DAL) was measured as the amount of unbuffered hydrogen ions delivered to the duodenum per unit time. Gas...

journal_title：Digestive diseases and sciences

authors： Lam SK,Isenberg JI,Grossman MI,Lane WH,Hogan DL

更新日期：1982-07-01 00:00:00

abstract：:Systemic sclerosis (SSc) is a connective tissue disorder of unknown etiology characterized by fibrosis and vascular obliteration in the skin, gastrointestinal tract, lungs, and heart. Our aim was to investigate the autoantibody profile in patients with esophageal involvement of SSc and to describe the relationship bet...

journal_title：Digestive diseases and sciences

authors： Savas N,Dagli U,Ertugrul E,Kuran S,Sahin B

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Tyrosine phosphorylation and dephosphorylation by protein tyrosine kinases and phosphatases (PTPs), respectively, play crucial roles in cellular signal transduction. Protein phosphatase non-receptor type 11 (PTPN11) is a positive signaling PTP that activates RAS and ERK signaling. Also, the PTPN11 binds with...

journal_title：Digestive diseases and sciences

authors： Kim JS,Shin OR,Kim HK,Cho YS,An CH,Lim KW,Kim SS

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Proton pump inhibitors (PPIs) are widely prescribed to treat gastrointestinal diseases. However, concerns have been raised regarding their long-term use. Gastric acid suppression may decrease iron absorption, and it remains uncertain whether iron-deficiency anemia may result from chronic PPI therapy. AIMS:W...

journal_title：Digestive diseases and sciences

authors： Sarzynski E,Puttarajappa C,Xie Y,Grover M,Laird-Fick H

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND AND AIM:Upper gastrointestinal (UGI) symptoms are common; however, the role of Helicobacter pylori and gastric corpus atrophy in the generation of these symptoms is controversial. The aim of this study was to determine the risk factors for UGI symptoms in adults in an endemic area of H. pylori infection. ME...

journal_title：Digestive diseases and sciences

authors： Lee SP,Lee SY,Kim JH,Sung IK,Park HS,Shim CS

更新日期：2017-06-01 00:00:00

abstract：:Interferon-alpha therapy for chronic hepatitis C in special patient populations raises a number of issues. Patients with hemophilia, kidney disease requiring hemodialysis, mixed cryoglobulinemia, HIV infection, and those receiving an allograft share some characteristics that complicate the treatment of hepatitis C vir...

journal_title：Digestive diseases and sciences

authors： Marcellin P,Boyer N,Behamou JP,Erlinger S

更新日期：1996-12-01 00:00:00

abstract：:Two hundred one consecutive patients with gallstone disease who had undergone cholecystectomy were analyzed to determine the relative frequency of occurrence of cholesterol and pigment gallstones and to identify distinguishing features of the two stone types. Cholesterol stones (CS) formed the majority (94%) of gallst...

journal_title：Digestive diseases and sciences

authors： Sarin SK,Kapur BM,Tandon RK

更新日期：1986-10-01 00:00:00

abstract：:We previously demonstrated that false-positive findings for tumor markers are frequently observed, and that the sensitivity of marker monitoring for early detection of the recurrence is low after curative resection of gastric cancer. The aim of this study was to investigate whether such characters are specific to gast...

journal_title：Digestive diseases and sciences

authors： Ohtsuka T,Nakafusa Y,Sato S,Kitajima Y,Tanaka M,Miyazaki K

更新日期：2008-06-01 00:00:00

abstract：:Response to interferon (IFN) therapy for chronic hepatitis C has been determined by the alteration of serum alanine aminotransferase (ALT) values. However, eradication of hepatitis C virus (HCV) could be another aim of the therapy. Thus, we serially measured serum HCV RNA levels during therapy and for at least 12 mont...

journal_title：Digestive diseases and sciences

authors： Aiyama T,Yoshioka K,Hirofuji H,Kusakabe A,Yamada M,Tanaka K,Kakumu S

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND AND AIM:Population-based endoscopic studies of esophageal eosinophilia and eosinophilic esophagitis are limited in the world. This study was aiming to describe features of esophageal eosinophilia and eosinophilic esophagitis in a representative sample of the adult in Shanghai, China. METHODS:As part of a la...

journal_title：Digestive diseases and sciences

authors： Ma X,Xu Q,Zheng Y,Zhao Y,Lu J,Wang R,Li Z,Zou D,He J

更新日期：2015-06-01 00:00:00

abstract：INTRODUCTION:Crohn's disease (CD) and ulcerative colitis (UC) are associated with considerable direct healthcare costs. There have been few comprehensive analyses of all IBD- and non-IBD comorbidities that determine direct costs in this population. METHODS:We used data from a validated cohort of patients with inflamma...

journal_title：Digestive diseases and sciences

authors： Cai W,Cagan A,He Z,Ananthakrishnan AN

更新日期：2020-05-20 00:00:00

abstract：:Primary hepatic lymphoma is a rare disease. We report five cases here and summarize clinical and pathologic features of our own and reported cases from Western countries and Japan. The total number of cases was 68. The age of patients ranged from 7 to 87 years (median 55) with a male-to-female ratio of 3.1:1. Chronic ...

journal_title：Digestive diseases and sciences

authors： Ohsawa M,Aozasa K,Horiuchi K,Kataoka M,Hida J,Shimada H,Oka K,Wakata Y

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Ectopic expression of gastric intrinsic factor (IF) has been described in rodent models of chronic gastritis. AIMS:The current study undertook to determine if ectopic IF was also present in chronic gastritis in humans and might identify the process of ectopic protein expression as part of the response to ch...

journal_title：Digestive diseases and sciences

authors： Shao JS,Carmel R,Alpers DH

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVES:Few studies compare gastroesophageal reflux (GER) parameters of cystic fibrosis (CF) children and symptomatic non-CF children. We aimed to compare the impedance-pH (IMP-pH) parameters for these two groups and to test the hypothesis that prolonged acid exposure in CF patients is due to delayed chemical cleara...

journal_title：Digestive diseases and sciences

authors： Woodley FW,Machado RS,Hayes D Jr,Di Lorenzo C,Kaul A,Skaggs B,McCoy K,Patel A,Mousa H

更新日期：2014-03-01 00:00:00

abstract：:Gastroesophageal reflux disease (GERD) is a common disease in infants and children. Prolonged (24-hr) pH monitoring in the esophagus for determination of increased acid exposure has, together with endoscopy, been the only routinely implemented method for GERD diagnosis. The recently introduced multiple intraluminal im...

journal_title：Digestive diseases and sciences

authors： Dalby K,Nielsen RG,Markoew S,Kruse-Andersen S,Husby S

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Individuals with inflammatory bowel disease (IBD) are at increased risk of developing colorectal cancer (CRC) compared with the general population. Previous studies show this risk is strongly associated with dysplasia, extent of disease, duration of disease, and degree of inflammation, while chemoprevention ...

journal_title：Digestive diseases and sciences

authors： Tang J,Sharif O,Pai C,Silverman AL

更新日期：2010-06-01 00:00:00