Nitric oxide synthase and VIP distribution in enteric nervous system in idiopathic chronic constipation.

abstract：BACKGROUND:Health education interventions are successful in modifying lifestyle. Functional health literacy (FHL) can determine patient adherence to clinic visits and procedures and may adversely impact the success of these interventions. AIMS:We sought to evaluate the hypothesis that a health education intervention w...

journal_title：Digestive diseases and sciences

authors： Shaw J,Patidar KR,Reuter B,Hajezifar N,Dharel N,Wade JB,Bajaj JS

更新日期：2020-09-05 00:00:00

abstract：BACKGROUND AND AIMS:The relationship between insulin resistance and post-ERCP pancreatitis (PEP) is not known. We aimed to determine the relation between pre-ERCP insulin resistance and risk of PEP, and to evaluate the relationship of insulin resistance with well-established risk factors for PEP. METHODS:Consecutive p...

journal_title：Digestive diseases and sciences

authors： Koksal AR,Boga S,Alkim H,Bayram M,Ergun M,Alkim C

更新日期：2016-08-01 00:00:00

abstract：:The pathogenesis of nonalcoholic steatohepatitis (NASH) remains poorly understood. Since inflammation and fatty changes are associated with hepatitis C (HCV) infection, we have tested the role of HCV in the genesis of NASH. Five consecutive cases of classic NASH were tested by Abbott anti-c100-3 EIA and polymerase cha...

journal_title：Digestive diseases and sciences

authors： Rogers DW,Lee CH,Pound DC,Kumar S,Cummings OW,Lumeng L

更新日期：1992-11-01 00:00:00

abstract：:Cyclin D1 plays an important role in the multi-step process of gastrointestinal tumorigenesis. We hypothesize that normal enterocytes over-expressing cyclin D1 will demonstrate a transformed phenotype. The nontumorigenic intestinal epithelial cell line, IEC-18, was transfected with the vector pMV7-CCND1, encoding cycl...

journal_title：Digestive diseases and sciences

authors： Kazanov D,Shapira I,Pick M,Kolker O,Liberman E,Deutsch V,Strier L,Dvory-Sobol H,Kunik T,Arber N

更新日期：2003-07-01 00:00:00

abstract：:Clinical observations reveal that alcohol intake is associated with an increase in upper gastrointestinal hemorrhage requiring hospitalization and that nitroglycerin or long-acting nitrates lower this risk. Nitroglycerin, a gastric vasodilator that can increase gastric fluid volume, protects the rodent stomach against...

journal_title：Digestive diseases and sciences

authors： Leung FW,Chan CC

更新日期：2007-11-01 00:00:00

abstract：:We have investigated the presence, duration, and clinical significance of granulocyte accumulation, using indium-111 granulocyte scanning, in patients following uncomplicated intestinal anastomosis. Eight patients underwent intestinal resection and anastomosis (right hemicolectomy, 5; sigmoid colectomy, 2; ileal resec...

journal_title：Digestive diseases and sciences

authors： Keshavarzian A,Gibson R,Guest J,Spencer J,Lavender JP,Hodgson HJ

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:Polymerase chain reaction (PCR) assays are the standard for detecting hepatitis C virus viremia. The transcription-mediated amplification (TMA)-based assay is more sensitive. METHODS:We retrospectively reviewed the charts of patients with a post-end of treatment (EOT) PCR-/TMA+ result to assess the clinical...

journal_title：Digestive diseases and sciences

authors： Thadani A,Harley J,Rubin J,Lebovics E

更新日期：2012-01-01 00:00:00

abstract：:Suppurative gastritis is an uncommon lesion and often an occult cause of upper abdominal pain without florid signs of a septic focus. There are two main phenotypic forms: (1) localized, also referred to as gastric abscess; and (2) diffuse, in which the differential diagnosis includes a more diverse range of benign and...

journal_title：Digestive diseases and sciences

authors： Coles M,Madray V,Cox K,Uy P,Sharma A

更新日期：2020-08-01 00:00:00

abstract：:Using conventional statistical analysis and multiple regression analysis, we investigated the viral and host factors that influence the response to recombinant interferon-alpha 2a therapy in patients with chronic hepatitis C. A total of 36 patients was randomly assigned to three administration schedules, 12 patients i...

journal_title：Digestive diseases and sciences

authors： Matsumoto A,Tanaka E,Suzuki T,Ogata H,Kiyosawa K

更新日期：1994-06-01 00:00:00

abstract：:Suspected risk factors for adenocarcinoma of the small bowel in Crohn's disease include surgically excluded small bowel loops, chronic fistulous disease, and male sex. Review of all seven University of Chicago cases failed to confirm any suspected risk factor. A case-control study was performed to identify possible al...

journal_title：Digestive diseases and sciences

authors： Lashner BA

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Acute variceal bleeding (AVB) in patients with cirrhosis is associated with high mortality, ranging from 12 to 20% at 6 weeks. The existing prognostic models for AVB lack precision and require further validation. AIM:In this prospective study, we aimed to develop and validate a new prognostic model for AVB,...

journal_title：Digestive diseases and sciences

authors： Rout G,Sharma S,Gunjan D,Kedia S,Saraya A,Nayak B,Singh V,Kumar R,Shalimar

更新日期：2019-08-01 00:00:00

abstract：:The bile acids in brown pigment stones and gallbladder bile were fractionated into free acids, glycine and taurine conjugates, and sulfates using diethylaminohydroxypropyl Sephadex LH-20 (DEAP-LH-20) column chromatography and were quantitated by gas chromatography. Twenty-eight cases of brown pigment stones were studi...

journal_title：Digestive diseases and sciences

authors： Akiyoshi T,Nakayama F

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Total parenteral nutrition (TPN), a necessary treatment for patients who cannot receive enteral nutrition, is associated with infectious complications due in part to a loss of intestinal epithelial barrier function (EBF). Using a mouse model of TPN, with enteral nutrient deprivation, we previously demonstrat...

journal_title：Digestive diseases and sciences

authors： Demehri FR,Krug SM,Feng Y,Lee IF,Schulzke JD,Teitelbaum DH

更新日期：2016-06-01 00:00:00

abstract：AIMS:The purpose of this retrospective study was to assess clinical outcomes of endoscopic bougie dilation of esophageal strictures after radiation therapy for head and neck cancer, and to assess the risk factors which affect the treatment success. METHODS:Thirty-one patients with esophageal stricture due to radiation...

journal_title：Digestive diseases and sciences

authors： Tuna Y,Koçak E,Dinçer D,Köklü S

更新日期：2012-02-01 00:00:00

abstract：:Although the association between acute pancreatitis and pleuropulmonary damage is well documented, so far no information on lung function in patients with chronic pancreatitis is available. In this study functional, radiological, and clinical investigations have been carried out in 42 patients affected by chronic calc...

journal_title：Digestive diseases and sciences

authors： Masoero G,Spinaci S,Arossa W,Andriulli A,Gaia E,De Pretis G,Dobrilla G,De la Pierre M

更新日期：1984-10-01 00:00:00

abstract：:Other studies have shown that both morphological and functional adaptation occur in the ileal mucosa after total colectomy and may be mediated by humoral factors. To elucidate the participation of peptide YY (PYY) in intestinal adaptation after total proctocolectomy with ileal pouch-anal anastomosis (IPAA), changes in...

journal_title：Digestive diseases and sciences

authors： Imamura M,Nakajima H,Mikami Y,Yamauchi H

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Proton pump inhibitors (PPIs) are widely prescribed to treat gastrointestinal diseases. However, concerns have been raised regarding their long-term use. Gastric acid suppression may decrease iron absorption, and it remains uncertain whether iron-deficiency anemia may result from chronic PPI therapy. AIMS:W...

journal_title：Digestive diseases and sciences

authors： Sarzynski E,Puttarajappa C,Xie Y,Grover M,Laird-Fick H

更新日期：2011-08-01 00:00:00

abstract：:Pulmonary injury with leukocyte infiltration is a frequent occurrence in obstructive cholangitis patients. We wished to evaluate the roles of reactive oxygen species and vascular cell adhesion molecule-1 (VCAM-1) in this distant organ failure. Wild type (WT) and transgenic (SODtg) mice overexpressing superoxide dismut...

journal_title：Digestive diseases and sciences

authors： Morise Z,Ueda M,Kitajima M,Epstein CJ,Granger DN,Grisham MB

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Systemic sclerosis (SS) patients with severe esophageal affection have impaired peristalsis. However, motor function evaluated in vivo by manometry and fluoroscopy does not provide detailed information about the individual contraction cycles. AIMS:To apply, for the first time in gastrointestinal (GI) patien...

journal_title：Digestive diseases and sciences

authors： Gregersen H,Villadsen GE,Liao D

更新日期：2011-12-01 00:00:00

abstract：:The hepatic stimulatory substance (HSS) extracted from weanling rat livers was purified 381,000-fold using chromatographic techniques including nondissociating polyacrylamide gel electrophoresis (nondenaturing PAGE). The activity of this highly purified HSS, named Acr-F4, was assessed in two in vivo models. In 40% hep...

journal_title：Digestive diseases and sciences

authors： Francavilla A,Barone M,Van Thiel DH,Mazzaferro V,Prelich JG,Starzl TE

更新日期：1991-05-01 00:00:00

abstract：:We present a case of collagenous colitis with evidence of terminal ileal involvement. The patient suffered from chronic watery diarrhea of three months' duration, and colonoscopy revealed a normal endoscopic appearance. Histologic examination of biopsies revealed a broad subepithelial band of collagen, with similar hi...

journal_title：Digestive diseases and sciences

authors： Lewis FW,Warren GH,Goff JS

更新日期：1991-08-01 00:00:00

abstract：:The ascitic fluid concentrations of cholesterol and fibronectin and the serum-ascites albumin difference were compared with two conventional tests of ascitic fluid, total protein and LDH, in their diagnostic ability for detection of malignancy in ascitic samples from 69 patients with ascites: 54 with ascites due to li...

journal_title：Digestive diseases and sciences

authors： Prieto M,Gómez-Lechón MJ,Hoyos M,Castell JV,Carrasco D,Berenguer J

更新日期：1988-07-01 00:00:00

abstract：:Segments of rat ileum and colon were infused in vivo to test if 0.1 M lactate, 10(-4) M H+, or both altered mucosal structure and function. In the first series of experiments, lactate concentration was kept at 0.1 M while H+ was varied from 10(-4) to 10(-7) M. Lactate and 10(-4) M H+ in the colon, and lactate and 10(-...

journal_title：Digestive diseases and sciences

authors： Saunders DR,Sillery J

更新日期：1982-01-01 00:00:00

abstract：:The role of mast cells, potential mediators of mucosal immunity and inflammation, was studied morphologically in the rectal mucosa in two acute diarrheal diseases, cholera and shigellosis. Quantitation of mucosal mast cells showed that they were significantly higher in the deeper lamina propria where blood vessels and...

journal_title：Digestive diseases and sciences

authors： Pulimood AB,Mathan MM,Mathan VI

更新日期：1998-09-01 00:00:00

abstract：:This study was conducted to determine the ion transport mechanisms in the normal mouse cecum and compare them to an inbred mouse model of colitis. The Ussing chamber-voltage clamp technique was used to monitor the short circuit current (I(sc)). The basal I(sc) in the normal cecum was 82.6 +/- 5.8 microA/cm2. It was no...

journal_title：Digestive diseases and sciences

authors： Homaidan FR,Tripodi J,Cheng P,Donovan V,Burakoff R

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND AND AIMS:The effect of the cystic fibrosis transmembrane conductance regulator protein (CFTR) defect in pancreatic insufficient (PI) patients with cystic fibrosis (CF) on the gastrointestinal pH profile is poorly defined. Adequate and efficient neutralization of the gastric acidity in the duodenum is importa...

journal_title：Digestive diseases and sciences

authors： Gelfond D,Ma C,Semler J,Borowitz D

更新日期：2013-08-01 00:00:00

abstract：AIM:To investigate whether a diagnostic delay is associated with a poor outcome in Crohn's disease (CD). METHODS:Medical and socioeconomic characteristics as well as medications and need for surgery of consecutive CD adults patients followed in three referral centers were prospectively recorded using an electronic dat...

journal_title：Digestive diseases and sciences

authors： Nahon S,Lahmek P,Paupard T,Lesgourgues B,Chaussade S,Peyrin-Biroulet L,Abitbol V

更新日期：2016-11-01 00:00:00

abstract：:The present paper evaluates the efficiency of Nissen fundoplication as an antireflux technique in a series of 51 patients with different grades of esophagitis. Follow-up time averaged 6.6 years. The evaluation includes a clinical assessment, endoscopic study, and 24-hr pH monitoring. The results reveal an acceptable r...

journal_title：Digestive diseases and sciences

authors： Martinez de Haro LF,Ortiz A,Parrilla P,Garcia Marcilla JA,Aguayo JL,Morales G

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:Controlled attenuation parameter (CAP) has been developed to estimate the extent of hepatic steatosis. AIMS:The purpose was to evaluate the usefulness of CAP in assessing hepatic steatosis and its change using magnetic resonance imaging proton density fat fraction (MRI-PDFF) as reference standard. METHODS:...

journal_title：Digestive diseases and sciences

authors： Wang JH,Ou HY,Yen YH,Chen CH,Lu SN

更新日期：2020-05-01 00:00:00

abstract：:We explored the hemodynamic effects of rapid injection of 0.9% saline and arterial blood into the canine superior mesenteric artery in anesthetized animals. Mesenteric artery blood flow and pressure were measured in the vessel distal to the site of injection. Injection rates were at or below the rate of blood flow in ...

journal_title：Digestive diseases and sciences

authors： Jacobson ED,Eldon C,Fondacaro JD

更新日期：1981-10-01 00:00:00