Budd-Chiari syndrome and Crohn's disease. An unreported association.

abstract：:Angiotensin II (Ang II) has been reported to promote tumor progression, tumor growth and angiogenesis in many cancers. We previously observed that angiotensin II type 1 receptors (AT1R) were upregulated in human gastric cancer and may be involved in the progression of gastric cancer. We studied the effects of AT1R ant...

journal_title：Digestive diseases and sciences

authors： Huang W,Wu YL,Zhong J,Jiang FX,Tian XL,Yu LF

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Diarrhea, a major pathological hallmark of inflammatory bowel disease, is characterized by a significant reduction in the expression and function of key intestinal ion transporters. The adoptive naïve CD4+ T cell transfer colitis is an immune-based, chronic colitis mouse model which resembles human Crohn's d...

journal_title：Digestive diseases and sciences

authors： Jayawardena D,Tyagi S,Nazmi A,Olivares-Villagómez D,Dudeja PK

更新日期：2020-06-01 00:00:00

abstract：:The initiating mechanisms involved in colonic injury are currently unknown. The goal of the current study was to examine the role of the inflammatory mediators reactive oxygen metabolites and proteases in an ex vivo model of selective epithelial permeability. Rats were prepared with exteriorized colonic chambers to wh...

journal_title：Digestive diseases and sciences

authors： Berin MC,Buell MG

更新日期：1995-10-01 00:00:00

abstract：:We report a rare case of secondary involvement of the gallbladder by metastatic renal cell carcinoma. A 71-year-old man was diagnosed as having a polypoid mass within the gallbladder when he underwent right nephrectomy for a renal cell carcinoma. A preoperative diagnosis of simultaneous carcinoma of the gallbladder wa...

journal_title：Digestive diseases and sciences

authors： Satoh H,Iyama A,Hidaka K,Nakashiro H,Harada S,Hisatsugu T

更新日期：1991-04-01 00:00:00

abstract：:Hereditary type 2 diabetes mellitus is a risk factor for chronic liver disease, and ~30 % of patients with liver cirrhosis develop diabetes. Diabetes mellitus has been associated with cirrhotic and non-cirrhotic hepatitis C virus liver infection, can aggravate the course the liver infection, and can induce a lower sus...

journal_title：Digestive diseases and sciences

authors： García-Compeán D,González-González JA,Lavalle-González FJ,González-Moreno EI,Villarreal-Pérez JZ,Maldonado-Garza HJ

更新日期：2016-02-01 00:00:00

abstract：:The effects of deoxycholic acid (DCA) on the intestinal microbiota, bile acid (BA) metabolism, and intestinal epithelium can be influenced by various factors. Depending on the specific conditions, DCA can be "bad" (proinflammatory) or "good" (anti-inflammatory). Mouse models of colitis show an increase in conjugated B...

journal_title：Digestive diseases and sciences

authors： Sitkin S,Pokrotnieks J

更新日期：2020-10-16 00:00:00

abstract：:Gastroesophageal reflux disease (GERD) is a common disease in infants and children. Prolonged (24-hr) pH monitoring in the esophagus for determination of increased acid exposure has, together with endoscopy, been the only routinely implemented method for GERD diagnosis. The recently introduced multiple intraluminal im...

journal_title：Digestive diseases and sciences

authors： Dalby K,Nielsen RG,Markoew S,Kruse-Andersen S,Husby S

更新日期：2007-09-01 00:00:00

abstract：:A defective epidermal growth factor receptor (EGFR) abrogates adaptation, while overexpression of EGFR or exogenous epidermal growth factor (EGF) enhances adaptation following small bowel resection (SBR). EGFR is predominantly located on the enterocyte basolateral membrane, yet luminal EGF is increased in injured muco...

journal_title：Digestive diseases and sciences

authors： Avissar NE,Wang HT,Miller JH,Iannoli P,Sax HC

更新日期：2000-06-01 00:00:00

abstract：:Other studies have shown that both morphological and functional adaptation occur in the ileal mucosa after total colectomy and may be mediated by humoral factors. To elucidate the participation of peptide YY (PYY) in intestinal adaptation after total proctocolectomy with ileal pouch-anal anastomosis (IPAA), changes in...

journal_title：Digestive diseases and sciences

authors： Imamura M,Nakajima H,Mikami Y,Yamauchi H

更新日期：1999-05-01 00:00:00

abstract：:Octreotide is an effective therapeutic option in controlling secretory diarrhea of varied etiology. However, marked patient-to-patient differences in the antidiarrheal effects necessitate titration of octreotide dose in individual patients to achieve optimal symptom control. A consensus development panel established g...

journal_title：Digestive diseases and sciences

authors： Harris AG,O'Dorisio TM,Woltering EA,Anthony LB,Burton FR,Geller RB,Grendell JH,Levin B,Redfern JS

更新日期：1995-07-01 00:00:00

abstract：:In the United States, more women than men seek health-care services for symptoms of irritable bowel syndrome (IBS). A number of explanations are given for this gender difference including the higher rates of somatic non-gastrointestinal symptoms and increased psychological distress reported by women with IBS. However,...

journal_title：Digestive diseases and sciences

authors： Cain KC,Jarrett ME,Burr RL,Rosen S,Hertig VL,Heitkemper MM

更新日期：2009-07-01 00:00:00

abstract：:This paper reports the results of a multicenter prospective study of 188 consecutive patients affected by gastric ulcer, verified by endoscopy, in whom the frequency of a mycotic infection of the lesion was evaluated as well as the eventual influence of such pathology on the efficiency of medical treatment, the healin...

journal_title：Digestive diseases and sciences

authors： Di Febo G,Miglioli M,Calò G,Biasco G,Luzza F,Gizzi G,Cipollini F,Rossi A,Barbara L

更新日期：1985-02-01 00:00:00

abstract：:This study was conducted to determine the ion transport mechanisms in the normal mouse cecum and compare them to an inbred mouse model of colitis. The Ussing chamber-voltage clamp technique was used to monitor the short circuit current (I(sc)). The basal I(sc) in the normal cecum was 82.6 +/- 5.8 microA/cm2. It was no...

journal_title：Digestive diseases and sciences

authors： Homaidan FR,Tripodi J,Cheng P,Donovan V,Burakoff R

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Corticosteroids and pentoxifylline reduce short-term mortality in severe alcoholic hepatitis (SAH), but not to the extent desired. Combining both drugs may lead to better survival, but has not yet been studied. AIM:To compare the efficacy of corticosteroids plus pentoxifylline with that of corticosteroids a...

journal_title：Digestive diseases and sciences

authors： Sidhu SS,Goyal O,Singla P,Gupta D,Sood A,Chhina RS,Soni RK

更新日期：2012-06-01 00:00:00

abstract：:Serum and urine concentrations of pancreatic polypeptide (PP) were measured during experimental acute hemorrhagic pancreatitis and small-bowel infarction in dogs. The mean serum PP concentration in animals with pancreatitis increased markedly after 1 hr and remained elevated, while the mean serum PP concentration in t...

journal_title：Digestive diseases and sciences

authors： Pappas TN,Yovos JG,Ellison EC,O'Dorisio TM,Cataland S,Pace WG,Carey LC

更新日期：1981-11-01 00:00:00

abstract：:To understand whether direct transmission of H. pylori occurs from infected mouse to noninfected mouse, the system using a mouse model we developed previously was tested. Six nude mice were challenged with H. pylori inocula; one group consisted of one challenged nude mouse 1 week after inoculation raised with four non...

journal_title：Digestive diseases and sciences

authors： Karita M,Matsumoto S,Kamei T,Shinohara K,Sugiyama T

更新日期：2005-06-01 00:00:00

abstract：:The effects of the water-soluble and delayed-release formulations of a nonsteroidal antiinflammatory drug, diclofenac, on the healing of gastroduodenal mucosal lesions were compared in a double-blind, double cross-over, placebo-controlled endoscopic study conducted in 14 healthy volunteers. Severe endoscopic lesions (...

journal_title：Digestive diseases and sciences

authors： Stadler P,Armstrong D,Margalith D,Saraga E,Stolte M,Lualdi P,Mautone G,Blum AL

更新日期：1991-05-01 00:00:00

abstract：:Sirtuins (SIRT), first described as nicotinamide adenine dinucleotide (NAD+)-dependent type III histone deacetylases, are produced by cells to support in the defense against chronic stress conditions such as metabolic syndromes, neurodegeneration, and cancer. SIRT-3 is one of the most studied members of the mitochondr...

journal_title：Digestive diseases and sciences

authors： De Matteis S,Granato AM,Napolitano R,Molinari C,Valgiusti M,Santini D,Foschi FG,Ercolani G,Vespasiani Gentilucci U,Faloppi L,Scartozzi M,Frassineti GL,Casadei Gardini A

更新日期：2017-08-01 00:00:00

abstract：:The gut microbiota is a vast ensemble of microorganisms inhabiting the mammalian gastrointestinal tract that can impact physiologic and pathologic processes. However, our understanding of the underlying mechanism for the dynamic interaction between host and gut microbiota is still in its infancy. The highly evolved ep...

journal_title：Digestive diseases and sciences

authors： Ye J,Wu W,Li Y,Li L

更新日期：2017-05-01 00:00:00

abstract：:A controlled trial has been carried out in order to compare the efficacy of enemas containing a high dosage of 5-ASA (4 g) versus enemas containing hydrocortisone 100 mg. The trial was conducted on 86 patients, 44 of whom received 5-ASA and 42 received hydrocortisone. The results were favorable in terms of clinical, s...

journal_title：Digestive diseases and sciences

authors： Campieri M,Gionchetti P,Belluzzi A,Brignola C,Migaldi M,Tabanelli GM,Bazzocchi G,Miglioli M,Barbara L

更新日期：1987-12-01 00:00:00

abstract：:To investigate the colonic adenoma-adenocarcinoma progression sequence, DNA ploidy analysis was performed on hyperplastic polyps to adenocarcinomas. DNA ploidy data were then compared with immunocytochemical staining for proliferating cell nuclear antigen (PCNA). In hyperplastic polyps to villous adenomas, all cases w...

journal_title：Digestive diseases and sciences

authors： Tomita T

更新日期：1995-05-01 00:00:00

abstract：:The characteristic features of a 48-year-old male presenting with isolated acromegaly caused by a GRH-producing pancreatic endocrine tumor bearing no relation to MEN1 was reported. The clinical features, laboratory findings, and sellar enlargement were improved after removal of the pancreatic tumor. The resected pancr...

journal_title：Digestive diseases and sciences

authors： Kawa S,Ueno T,Iijima A,Midorikawa T,Fujimori Y,Tokoo M,Oguchi H,Kiyosawa K,Imai Y,Kaneko G,Kuroda T,Hashizume K,Osamura RY,Katakami H

更新日期：1997-07-01 00:00:00

abstract：:H. pylori may colonize columnar-lined esophagus, although an etiologic role in esophageal adenocarcinoma is unproven. H. pylori can adhere to intestinal metaplasia in the stomach. This study was designed to examine if H. pylori adheres to specialized intestinal metaplasia in columnar-lined esophagus. Esophageal biopsi...

journal_title：Digestive diseases and sciences

authors： Sharma VK,Demian SE,Taillon D,Vasudeva R,Howden CW

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) screening is a priority for the Veteran's Health Administration (VHA). Optimizing fecal occult blood testing (FOBT) is integral to CRC screening in health care systems. AIMS:The purpose of this study was to characterize the utilization of CRC testing in a large integrated health care...

journal_title：Digestive diseases and sciences

authors： Long MD,Lance T,Robertson D,Kahwati L,Kinsinger L,Fisher DA

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Globus sensation is common, but its pathogenesis is not yet clear. AIMS:Our purpose was to investigate subjective perception of swallowing and esophageal motility by combined multichannel intraluminal impedance and manometry (MII-EM) for patients with globus sensation. METHODS:Combined MII-EM was performed...

journal_title：Digestive diseases and sciences

authors： Chen CL,Yi CH,Liu TT

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Prior to the consensus guideline conference in 2007, eosinophilic esophagitis (EoE) was uncommon dominated by the fibrostenotic phenotype, but over the past decade has become a common cause of dysphagia with more inflammatory phenotypes diagnosed. We assessed the impact of guideline definitions on t...

journal_title：Digestive diseases and sciences

authors： Lipka S,Boyce HW,Kumar A,Richter JE

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Matrix metalloproteinase-2 (MMP-2), a type IV collagenase secreted by activated hepatic stellate cells (HSCs), is upregulated in chronic liver disease and is considered a profibrotic mediator due to its proliferative effect on cultured HSCs and ability to degrade normal liver matrix. Although associ...

journal_title：Digestive diseases and sciences

authors： Radbill BD,Gupta R,Ramirez MC,DiFeo A,Martignetti JA,Alvarez CE,Friedman SL,Narla G,Vrabie R,Bowles R,Saiman Y,Bansal MB

更新日期：2011-02-01 00:00:00

abstract：:Breath methane was studied in 394 subjects. Among 152 controls, 50.0% produced methane--42.1% of males and 57.9% of females. One hundred sixteen patients with gastrointestinal diseases were studied. Among 32 with Crohn's disease, only 2 (6.1%) produced methane, as well as 16 of 51 ulcerative colitis patients (31.4%) a...

journal_title：Digestive diseases and sciences

authors： Peled Y,Weinberg D,Hallak A,Gilat T

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND:Barrett's esophagus (BE) is characterized by a distinct Th2-predominant cytokine profile. However, antigens that shift the immune response toward the Th2 profile are unknown. AIM:We examined the effects of rebamipide on the esophageal microbiome and BE development in a rat model. METHODS:BE was induced by ...

journal_title：Digestive diseases and sciences

authors： Kohata Y,Nakahara K,Tanigawa T,Yamagami H,Shiba M,Watanabe T,Tominaga K,Fujiwara Y,Arakawa T

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:In previous studies the NFKBIA 3'UTR (untranslated region) AA genotype was associated with Crohn's disease (CD), while the NFKB1-94ins/delATTG mutation increased the risk for ulcerative colitis (UC). The aim of our study was to investigate these two polymorphisms and patients' response to medical therapy and/or...

journal_title：Digestive diseases and sciences

authors： Szamosi T,Lakatos PL,Hungarian IBD Study Group.,Szilvasi A,Lakatos L,Kovacs A,Molnar T,Altorjay I,Papp M,Szabo O,Satori A,Tulassay Z,Miheller P,Horvath HC,Papp J,Tordai A,Andrikovics H

更新日期：2009-02-01 00:00:00