Gender differences in gastrointestinal, psychological, and somatic symptoms in irritable bowel syndrome.


:In the United States, more women than men seek health-care services for symptoms of irritable bowel syndrome (IBS). A number of explanations are given for this gender difference including the higher rates of somatic non-gastrointestinal symptoms and increased psychological distress reported by women with IBS. However, these gender differences are found in studies that rely on retrospective recall with little attention to age or reproductive status. The purpose of the current analysis was to prospectively compare the frequency (days/month of moderate to severe based on a daily diary) of somatic, gastrointestinal (GI), and psychological distress symptoms, in menstruating women (N = 89) and postmenopausal women (N = 66) to men (N = 32) with IBS. In addition, the correlation between daily symptoms and daily report of overall health was evaluated. Postmenopausal women reported significantly more GI pain/discomfort symptoms, especially bloating and abdominal distension, than men, however these differences are greatly attenuated when age is controlled for. Both postmenopausal and menstruating women reported significantly more somatic symptoms (especially joint pain and muscle pain) than men with IBS. The effect was stronger in postmenopausal women, whose somatic symptoms were also higher than menstruating women (P = 0.014). Fatigue and stress were higher in women than men but anxiety and depression were not. All three types of symptoms were strongly correlated with self-rating of health, both across and within-person. Gender-related differences in GI and somatic symptoms are apparent in persons with IBS, more strongly in postmenopausal women. The presence of somatic symptoms in postmenopausal women with IBS may challenge clinicians to find suitable therapeutic options.


Dig Dis Sci


Cain KC,Jarrett ME,Burr RL,Rosen S,Hertig VL,Heitkemper MM




Has Abstract


2009-07-01 00:00:00












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    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,多中心研究


    authors: Jacobson BC,Shami VM,Faigel DO,Larghi A,Kahaleh M,Dye C,Pedrosa M,Waxman I

    更新日期:2007-03-01 00:00:00

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    journal_title:Digestive diseases and sciences

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    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章


    authors: Traube J,Simpson S,Riddell RH,Levin B,Kirsner JB

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    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章


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    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章


    authors: Cui N,Madsen KL,Friend DR,Stevenson BR,Fedorak RN

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    pub_type: 临床试验,杂志文章,随机对照试验


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    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章


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    pub_type: 杂志文章


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    pub_type: 杂志文章


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    pub_type: 杂志文章


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    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章


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    pub_type: 杂志文章


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    pub_type: 杂志文章


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    更新日期:2012-11-01 00:00:00