DNA ploidy and proliferating cell nuclear antigen in colonic adenomas and adenocarcinomas.

abstract：BACKGROUND:Heat shock protein 70-2 (HSP70-2) has a cytoprotective role in various conditions and also protects the gastric mucosa. Recently, polymorphism of HSP70-2 at position 1267 was suggested to be associated with carcinogenesis. We investigated the association of this polymorphism with the risk of gastric cancer i...

journal_title：Digestive diseases and sciences

authors： Shibata T,Arisawa T,Tahara T,Yoshioka D,Maruyama N,Fujita H,Kamiya Y,Nakamura M,Nagasaka M,Iwata M,Takahama K,Watanabe M,Hirata I,Nakano H

更新日期：2009-01-01 00:00:00

abstract：:Since the publication of the last extensive review of hepatitis vaccines, use of inactivated hepatitis A vaccines has been extended to high-risk regions of the United States and specific patient groups, such as those with chronic liver disease, and use of the recombinant hepatitis B vaccines has been recommended for o...

journal_title：Digestive diseases and sciences

authors： Koff RS

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Concerns over the hypothetical adverse effects of water absorption and the disturbance of serum sodium and potassium levels prompted a quality assurance evaluation of water exchange (WE) colonoscopy. AIM:The purpose of this study was to evaluate the balance of water infused and suctioned in WE colonoscopy, ...

journal_title：Digestive diseases and sciences

authors： Leung JW,Siao-Salera R,Abramyan O,Mann SK,Ward G,Yen A,Gutierrez R,Leung FW

更新日期：2014-03-01 00:00:00

abstract：:We previously reported that various gastric irritants induced both apoptosis and necrosis in cultured gastric mucosal cells. In a continuation of this work, the present study has examined the effects of prostaglandin E2 (PGE2), a cytoprotective factor for gastric mucosa in vivo, on gastric irritant-induced apoptosis a...

journal_title：Digestive diseases and sciences

authors： Hoshino T,Takano T,Tsutsumi S,Tomisato W,Tsuchiya T,Mizushima T

更新日期：2002-10-01 00:00:00

abstract：:The effects of Sulglycotide were evaluated in a pilot study of active H. pylori+ atrophic gastritis. Ten informed patients (mean age 51 +/- 13 years) entered a double-blind study. Five received Sulglycotide 400 mg three times a day for one year, the other 5, placebo. At 0, 30, 90, 270, and 360 days of treatment, patie...

journal_title：Digestive diseases and sciences

authors： Bazuro GE,Dezi A,Pallotta L,Masci P,Teodori L,Trinca ML,Koch M,Capurso L

更新日期：1996-01-01 00:00:00

abstract：:By using two-color immunofluorescence with fluorescein isothiocyanate (FITC) and phycoerythrin (PE)-labelled monoclonal antibodies and multiparameter flow cytometry, we investigated lamina propria lymphocyte subsets of patients with ulcerative colitis (UC) and Crohn's disease (CD). Leu-3/Leu-2 (CD4/CD8) ratio of lamin...

journal_title：Digestive diseases and sciences

authors： Senju M,Wu KC,Mahida YR,Jewell DP

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:The aim of this retrospective study was to evaluate the success rate and complications of three precut techniques of sphincterotomy after failure of conventional techniques of cannulation of common bile duct (CBD). PATIENTS AND METHODS:Between January 2003 and October 2011, 2,903 consecutive ERCPs were perf...

journal_title：Digestive diseases and sciences

authors： Katsinelos P,Gkagkalis S,Chatzimavroudis G,Beltsis A,Terzoudis S,Zavos C,Gatopoulou A,Lazaraki G,Vasiliadis T,Kountouras J

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:The NIH-sponsored Patient-Reported Outcomes Measurement Information System (PROMIS) Gastrointestinal (GI) Symptoms scales were developed to assess patients' GI symptoms in clinical settings. AIMS:To assess responsiveness to change and provide minimally important difference (MID) estimates for the PROMIS GI ...

journal_title：Digestive diseases and sciences

authors： Khanna D,Hays RD,Shreiner AB,Melmed GY,Chang L,Khanna PP,Bolus R,Whitman C,Paz SH,Hays T,Reise SP,Spiegel B

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Anemia is a common systemic complication of inflammatory bowel disease (IBD) and is associated with worse disease outcomes, quality of life, and higher healthcare costs. AIMS:The purpose of this study was to determine how anemia severity impacts healthcare resource utilization and if treatment of anemia was...

journal_title：Digestive diseases and sciences

authors： Blaney H,Vu P,Mathew A,Snelling R,England J,Duong C,Hammonds K,Johnson C

更新日期：2020-09-05 00:00:00

abstract：:Acute erosions of the stomach may occur in association with human spinal cord injuries. Erosion of the glandular portion of the stomach also occurs after cervical cord transection in the rat. Reports on the effects of antacids and cimetidine in the prevention of acute "stress" erosions in animals and humans have shown...

journal_title：Digestive diseases and sciences

authors： Sigman HH,Gillich A

更新日期：1982-03-01 00:00:00

abstract：:Pulmonary injury with leukocyte infiltration is a frequent occurrence in obstructive cholangitis patients. We wished to evaluate the roles of reactive oxygen species and vascular cell adhesion molecule-1 (VCAM-1) in this distant organ failure. Wild type (WT) and transgenic (SODtg) mice overexpressing superoxide dismut...

journal_title：Digestive diseases and sciences

authors： Morise Z,Ueda M,Kitajima M,Epstein CJ,Granger DN,Grisham MB

更新日期：2002-03-01 00:00:00

abstract：:The role of HBV precore mutations in the spontaneous reactivation of chronic hepatitis B (CHB) is currently unknown. We studied 10 patients with CHB; five were HBeAg+ (group I) and five were anti-HBe+ (group II). All 10 had spontaneous reactivation of CHB as defined by the appearance of clinical symptoms along with an...

journal_title：Digestive diseases and sciences

authors： Laskus T,Rakela J,Tong MJ,Persing DH

更新日期：1994-09-01 00:00:00

abstract：:An altered adaptive response of the pancreas and small intestine to nutritional stress has an adverse impact upon nutritional status in elderly humans or senescent rats. We evaluated the effects of a pancreatic extract nutritional supplement on intestinal mucosa adaptation in LPS-treated aged rats. Endotoxemic rats we...

journal_title：Digestive diseases and sciences

authors： Farges MC,Raul F,Cezard JP,Davot P,Meunier MT,Cynober L,Vasson MP

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:We hypothesized that the severity of dextran sodium sulfate (DSS)-induced colitis could differ between DSS preparations of the same molecular weight, and that this difference may be affected by the sulfur content. To test this, we used three DSS preparations of similar molecular weights but with different su...

journal_title：Digestive diseases and sciences

authors： Bamba S,Andoh A,Ban H,Imaeda H,Aomatsu T,Kobori A,Mochizuki Y,Shioya M,Nishimura T,Inatomi O,Sasaki M,Saitoh Y,Tsujikawa T,Araki Y,Fujiyama Y

更新日期：2012-02-01 00:00:00

abstract：:Concentration and voltage dependence of Mg transport across the rat duodenum was measured in an Ussing chamber. Mucosa (m) to serosa (s) Mg flux exhibits a cellular fraction comparable to that found for Ca. Mg sm flux is purely diffusive and probably restricted to the paracellular pathway. At all concentrations betwee...

journal_title：Digestive diseases and sciences

authors： Karbach U,Schmitt A,Saner FH

更新日期：1991-11-01 00:00:00

abstract：:Both intracellular calcium ions and neural input are important in esophageal smooth muscle contraction. The aim of this study was to compare the effects of well-tolerated doses of the calcium-channel blocker, nifedipine (20 mg sublingually/buccally) with the anticholinergic, propantheline bromide (15 mg orally) and th...

journal_title：Digestive diseases and sciences

authors： Hongo M,Traube M,McCallum RW

更新日期：1984-04-01 00:00:00

abstract：:Hereditary type 2 diabetes mellitus is a risk factor for chronic liver disease, and ~30 % of patients with liver cirrhosis develop diabetes. Diabetes mellitus has been associated with cirrhotic and non-cirrhotic hepatitis C virus liver infection, can aggravate the course the liver infection, and can induce a lower sus...

journal_title：Digestive diseases and sciences

authors： García-Compeán D,González-González JA,Lavalle-González FJ,González-Moreno EI,Villarreal-Pérez JZ,Maldonado-Garza HJ

更新日期：2016-02-01 00:00:00

abstract：:Our objective was to investigate the expression of HMGA1 mRNA and protein in hepatocellular carcinoma (HCC) and the correlation between its expression and clinical pathological characteristics and prognosis. HMGA1 expression was determined at both the mRNA level and the protein level in 30 HCC tissues and their corres...

journal_title：Digestive diseases and sciences

authors： Chang ZG,Yang LY,Wang W,Peng JX,Huang GW,Tao YM,Ding X

更新日期：2005-10-01 00:00:00

abstract：:This article [1] is retracted at the request of Editor-in-Chief. ...

journal_title：Digestive diseases and sciences

authors： Zong G,Xu Z,Zhang S,Shen Y,Qiu H,Zhu G,He S,Tao T,Chen X

更新日期：2019-11-11 00:00:00

abstract：:The possibility of obtaining oral desensitization in patients with food allergy is still a matter of debate. We decided to evaluate the safety and efficacy of standardized protocols for oral desensitization with the most common food allergens. Forty-two children (ages up to 16 years) diagnosed as affected by food alle...

journal_title：Digestive diseases and sciences

authors： Patriarca G,Nucera E,Pollastrini E,Roncallo C,De Pasquale T,Lombardo C,Pedone C,Gasbarrini G,Buonomo A,Schiavino D

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Ulcerative colitis (UC) patients with progression of their disease despite optimized medical therapy may warrant "curative" proctocolectomy with end ileostomy or ileo-anal pouch (IPAA) anastomosis. The aim of our study was to assess the incidence of later recurrent ileitis that lead to altering the ...

journal_title：Digestive diseases and sciences

authors： Shamah S,Schneider J,Korelitz BI

更新日期：2018-02-01 00:00:00

abstract：:Minimal lesions of the small bowel are mucosal changes characterized by an increased number of intraepithelial lymphocytes (with or without crypt hyperplasia) and normal villous architecture. Such changes are associated with a wide spectrum of conditions, ranging from food intolerances to infections, and from drugs to...

journal_title：Digestive diseases and sciences

authors： Volta U,Caio G,Ghirardi C,Lungaro L,Mansueto P,Carroccio A,De Giorgio R

更新日期：2020-10-01 00:00:00

abstract：:The objective of this study was to determine if HCV can be transmitted from patient to patient in psychiatric institutions and to determine possible routes of infection. We did a cross-sectional survey of 196 Japanese psychiatric patients tested for HCV and HBV markers and 400 age- and sex-matched controls. Anti-HCV w...

journal_title：Digestive diseases and sciences

authors： Sawayama Y,Hayashi J,Kakuda K,Furusyo N,Ariyama I,Kawakami Y,Kinukawa N,Kashiwagi S

更新日期：2000-02-01 00:00:00

abstract：:As infection influences the pathogenesis and presentation of celiac disease, we investigated the expression of natural antibiotics in this condition. Twenty-three adults were prospectively studied: 10 controls and 13 subjects with untreated celiac disease. Distal duodenal biopsies were taken at baseline and after 6 mo...

journal_title：Digestive diseases and sciences

authors： Taha AS,Faccenda E,Angerson WJ,Balsitis M,Kelly RW

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND AND AIM:To explore the CT signs which permit estimation of clinically severe portal hypertension (PH) [≥ 12 of hepatic vein pressure gradient (HVPG)]. METHODS:One-hundred and seven consecutive patients who underwent HVPG measurement in the PH group and 52 controls were included. The diameters of main portal...

journal_title：Digestive diseases and sciences

authors： Lee JY,Kim TY,Jeong WK,Kim Y,Kim J,Kim KW,Kim YH,Sohn JH

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:In patients with chronic pancreatitis (CP), pain relief is a dilemma. Antioxidants with pregabalin therapy have been reported to be useful. Hence, this study was carried out to determine the efficacy of the combination of antioxidant and pregabalin therapy in reducing pain in patients with CP. METHODS:This ...

journal_title：Digestive diseases and sciences

authors： Sureshkumar S,Omang A,Anandhi A,Rajesh BS,Abdulbasith KM,Vijayakumar C,Palanivel C,Pazhanivel M,Kate V

更新日期：2020-11-18 00:00:00

abstract：BACKGROUND:Improved survival with chronic liver disease (CLD) and increased incidence in the older has led to a rapidly expanding population which faces similar "geriatric syndromes" as the general population. With risk factors such as autonomic dysfunction, cognitive impairment, and muscle abnormalities in CLD it is e...

journal_title：Digestive diseases and sciences

authors： Frith J,Kerr S,Robinson L,Elliott CS,Wilton K,Jones DE,Day CP,Newton JL

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Peppermint oil is well known to inhibit smooth muscle contractions, and its topical administration during colonoscopy is reported to reduce colonic spasms. AIMS:We aimed to assess whether oral administration of IBGard™, a sustained-release peppermint oil formulation, before colonoscopy reduces spasms and im...

journal_title：Digestive diseases and sciences

authors： Han JY,Moosvi Z,Duh E,Park S,Albers GC,Samarasena JB,Karnes W

更新日期：2020-06-09 00:00:00

abstract：:Cyclic vomiting syndrome is a disorder characterized by recurrent episodes of nausea and vomiting with complete resolution of symptoms between attacks. Nitric oxide plays a critical role in regulating several components of gastrointestinal mucosal defense and injury. Interleukin-6 has a wide variety of actions in the ...

journal_title：Digestive diseases and sciences

authors： Zicari A,Corrado G,Pacchiarotti C,Lucarelli S,Frediani T,Cavaliere M,Porcelli M,Cardi E

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Biliary cannulation failure is a major problem during endoscopic retrograde cholangiopancreatography. It remains unclear how duodenal papilla morphology affects biliary cannulation. Therefore, we proposed a new classification system for the duodenal papilla based on oral protrusion pattern (ratio of the leng...

journal_title：Digestive diseases and sciences

authors： Watanabe M,Okuwaki K,Kida M,Imaizumi H,Yamauchi H,Kaneko T,Iwai T,Hasegawa R,Miyata E,Masutani H,Tadehara M,Adachi K,Koizumi W

更新日期：2019-08-01 00:00:00