Attenuation of colonic inflammation by PPARgamma in intestinal epithelial cells: effect on Toll-like receptor pathway.

abstract：BACKGROUND:HAb18G/CD147 expression has been associated with many tumor invasion molecules, which play important roles in recurrence and poor differentiation of esophageal squamous cell carcinoma (ESCC). However, the clinical implications of HAb18G/CD147 in ESCC are still unclear. AIMS:In this study, we clarified the c...

journal_title：Digestive diseases and sciences

authors： Zhu S,Li Y,Mi L,Zhang Y,Zhang L,Gong L,Han X,Yao L,Lan M,Chen Z,Zhang W

更新日期：2011-12-01 00:00:00

abstract：:Modafinil may be a potentially effective treatment for primary biliary cirrhosis (PBC)-related fatigue. About 42 patients were given a 3-day trial of 100-200 mg modafinil. Response was defined as increased energy, decreased somnolence and sleep requirements, and improved daily function. Patients with positive response...

journal_title：Digestive diseases and sciences

authors： Ian Gan S,de Jongh M,Kaplan MM

更新日期：2009-10-01 00:00:00

abstract：:The protein ornithine decarboxylase antizyme (AZ) is inhibitory to both polyamine transport and synthesis. Experiments were performed to examine the distribution and regulation of AZ mRNA in cells of the small intestinal epithelium, a tissue exposed to high concentrations of extracellular polyamines and high levels of...

journal_title：Digestive diseases and sciences

authors： Gill JE,Christian JF,Seidel ER

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:Helminth infection has been proven to reduce the severity of experimental inflammatory bowel disease (IBD). The excretory-secretory proteins of helminths play an important role in the process of immunomodulation. AIMS:In the present study, we aimed to investigate the protective potential of recombinant Tric...

journal_title：Digestive diseases and sciences

authors： Du L,Tang H,Ma Z,Xu J,Gao W,Chen J,Gan W,Zhang Z,Yu X,Zhou X,Hu X

更新日期：2011-10-01 00:00:00

abstract：:To examine the differentiating parameters between cholesterol and pigment gallstones, we compared the nucleation times, concentrations of biliary lipid and protein, and the distribution of vesicular cholesterol in gallbladder bile of 16 patients with cholesterol, eight patients with black pigment gallstones, and nine ...

journal_title：Digestive diseases and sciences

authors： Chijiiwa K,Hirota I,Noshiro H

更新日期：1993-01-01 00:00:00

abstract：:Previous studies have found a widely variable prevalence of dysplasia and cancer in colonic strictures in patients with ulcerative colitis. Consequently, therapeutic recommendations are conflicting. To better assess the prevalence, we reviewed the clinical and pathological findings in all 27 patients with ulcerative c...

journal_title：Digestive diseases and sciences

authors： Lashner BA,Turner BC,Bostwick DG,Frank PH,Hanauer SB

更新日期：1990-03-01 00:00:00

abstract：:The efficacy of tiotidine, a new H2-receptor antagonist, in reducing nocturnal acid secretion of duodenal ulcer patients (N = 12, ages 21-60 years) was investigated. Different doses of tiotidine, 25, 50, 100, and 150 mg or placebo, were given as a single oral dose and acid secretion collected overnight. Tiotidine prod...

journal_title：Digestive diseases and sciences

authors： Valenzuela JE,Strecker RB,Douglas AP

更新日期：1981-05-01 00:00:00

abstract：:The gut microbiota is a vast ensemble of microorganisms inhabiting the mammalian gastrointestinal tract that can impact physiologic and pathologic processes. However, our understanding of the underlying mechanism for the dynamic interaction between host and gut microbiota is still in its infancy. The highly evolved ep...

journal_title：Digestive diseases and sciences

authors： Ye J,Wu W,Li Y,Li L

更新日期：2017-05-01 00:00:00

abstract：:Local or national policy, patients' preferences, safety and/or economic concerns, or reimbursement issues may dictate stopping drug in inflammatory bowel diseases (IBD) patients. Sustained deep remission is an important predictor of a better outcome after anti-tumor necrosis (TNF) factor therapy discontinuation, inclu...

journal_title：Digestive diseases and sciences

authors： Williet N,Paul S,Peyrin-Biroulet L,Roblin X

更新日期：2016-04-01 00:00:00

abstract：:In a retrospective study, 50 patients with obvious necrotizing pancreatitis (NP) were allocated in four groups according to the morphological aspects of the necrosis. Appearance of ascite (N1), extrapancreatic spread of necrosis towards neighboring organs (N2), a large amount of necrosis (N3), and infected necrosis (N...

journal_title：Digestive diseases and sciences

authors： Le Mée J,Janny S,Sauvanet A,Werner P,Belghiti J

更新日期：1997-08-01 00:00:00

abstract：AIM:To identify the clinical and biochemical predictors of histologic disease severity in patients with non-alcoholic steatohepatitis (NASH). METHOD:Clinical, anthropometric and biochemical data of 71 consecutive patients with a histological diagnosis of NASH were retrieved from the medical database. The histologic cr...

journal_title：Digestive diseases and sciences

authors： Singh DK,Sakhuja P,Malhotra V,Gondal R,Sarin SK

更新日期：2008-07-01 00:00:00

abstract：:The techniques commonly used to evaluate the transit of contents through the gut feature some limitations for being either inaccurate, invasive, inconvenient, or potentially dangerous for the subjects. Aim of this study was to establish a safe, noninvasive and accurate technique for the measurement of segmental oroana...

journal_title：Digestive diseases and sciences

authors： Basile M,Neri M,Carriero A,Casciardi S,Comani S,Del Gratta C,Di Donato L,Di Luzio S,Macri MA,Pasquarelli A

更新日期：1992-10-01 00:00:00

abstract：:Exposure of the stomach for 30 min to acidified sodium taurocholate (TC) (1-20 mM) or sodium salicylate (SA) (10-80 mM) caused a reduction of transmucosal PD and an increase of luminal pH in anesthetized rats, in a concentration-related manner. Acidified aspirin (ASA) (10-80 mM) reduced PD in the same manner, without ...

journal_title：Digestive diseases and sciences

authors： Takeuchi K,Ohno T,Okabe S

更新日期：1987-08-01 00:00:00

abstract：:The frequent association of stromal tumors with neurofobromatosis raises high suspicion of a possible correlation between the two entities. The aim of this study was to analyze clinicopathologic features of patients with concomitant neurofibromatosis and gastrointestinal stromal tumors and to discuss the molecular bas...

journal_title：Digestive diseases and sciences

authors： Cheng SP,Huang MJ,Yang TL,Tzen CY,Liu CL,Liu TP,Hsiao SC

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:The pentapeptide ghrelin agonist, relamorelin, accelerates colonic transit in patients with chronic constipation (CC). In a murine model, relamorelin decreased excitability of colonic circular smooth muscle cells and colonic intraluminal pressure. AIM:To determine short-term effects of relamorelin on coloni...

journal_title：Digestive diseases and sciences

authors： Acosta A,Camilleri M,Busciglio I,Boldingh A,Nelson AD,Burton D

更新日期：2016-03-01 00:00:00

abstract：:The prevalence of the recently described deamidated gliadin peptide antibodies was compared with that of the routinely used antigliadin, antiendomysial, and tissue transglutaminase antibodies in the sera of 128 untreated celiac patients and 134 controls. Sensitivity and specificity for celiac disease were 83.6 and 90....

journal_title：Digestive diseases and sciences

authors： Volta U,Granito A,Fiorini E,Parisi C,Piscaglia M,Pappas G,Muratori P,Bianchi FB

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Elderly patients with chronic hepatitis C virus (HCV) infection represent an understudied population, and little is known regarding the predictive factors for sustained virological response (SVR) to antiviral therapy in these patients. AIMS:To evaluate the efficacy of pegylated interferon (PEG-IFN) and riba...

journal_title：Digestive diseases and sciences

authors： Giannini EG,Basso M,Savarino V,Picciotto A

更新日期：2010-11-01 00:00:00

abstract：:The effects of the water-soluble and delayed-release formulations of a nonsteroidal antiinflammatory drug, diclofenac, on the healing of gastroduodenal mucosal lesions were compared in a double-blind, double cross-over, placebo-controlled endoscopic study conducted in 14 healthy volunteers. Severe endoscopic lesions (...

journal_title：Digestive diseases and sciences

authors： Stadler P,Armstrong D,Margalith D,Saraga E,Stolte M,Lualdi P,Mautone G,Blum AL

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:ESD allows higher rates of en-bloc and R0 resections, but has occasionally complications such as aspiration pneumonia. Factors associated with aspiration pneumonia are not completely understood. AIMS:To analyze the relationship between aspiration pneumonia and preoperative factors including pulmonary functi...

journal_title：Digestive diseases and sciences

authors： Matsumi A,Takenaka R,Ando C,Sato Y,Takei K,Yasutomi E,Okanoue S,Oka S,Kawai D,Kataoka J,Takemoto K,Tsugeno H,Fujiki S,Kawahara Y

更新日期：2017-11-01 00:00:00

abstract：:Intravenous administration of platelet-activating factor (PAF) induces extensive damage in rat gastric mucosa. The aim of the present study was to examine whether the presence or absence of acid in the gastric lumen could modify the PAF-induced gastric damage. The effects of inhibition of basal and pentagastrin-stimul...

journal_title：Digestive diseases and sciences

authors： Piqué JM,Pérez Ayuso RM,Bilbao J,Terés J

更新日期：1991-12-01 00:00:00

abstract：:Ascites is more difficult to detect when only a small quantity is present. The aim of this pilot study was to determine the optimal bowel sound characteristics in order to distinguish no ascites from small-volume ascites by advanced processing of bowel sound wave patterns. This analysis results in the definition of th...

journal_title：Digestive diseases and sciences

authors： Liatsos C,Hadjileontiadis LJ,Mavrogiannis C,Patch D,Panas SM,Burroughs AK

更新日期：2003-08-01 00:00:00

abstract：:The aim of this study was to clarify the pathogenesis of Helicobacter pylori-negative duodenal ulcer (DU) by investigating the meal-stimulated serum gastrin (SG) response. The subjects were 9 patients with H. pylori-negative DU, 28 H. pylori-positive DU, 11 H. pylori-positive volunteers, and 30 H. pylori-negative volu...

journal_title：Digestive diseases and sciences

authors： Kamada T,Haruma K,Kusunoki H,Miyamoto M,Ito M,Kitadai Y,Yoshihara M,Chayama K,Tahara K,Kawamura Y

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:Both 22- and 25-gauge needles are used for endoscopic ultrasound (EUS)-guided fine-needle aspiration (FNA) of lesions, yet limited data exist on whether either offers an advantage over the other in terms of specimen cellularity and quality. AIM:The aim of this study was to compare sample quality for 22- and...

journal_title：Digestive diseases and sciences

authors： Lee JH,Stewart J,Ross WA,Anandasabapathy S,Xiao L,Staerkel G

更新日期：2009-10-01 00:00:00

abstract：:The indications for surgery on cavernous hemangiomas, the most common benign tumors of the liver, remain unclear. This study reviewed 43 patients with cavernous hemangioma of the liver who underwent hepatic resection from 1984 to 2000. Patients were divided into three groups based on the reasons for surgery. Group I c...

journal_title：Digestive diseases and sciences

authors： Tsai HP,Jeng LB,Lee WC,Chen MF

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Data on ERCP nurses and associate (ERCP-NA) training and comfort are lacking. Healthcare industry representative (HCIR) influence may be greater in low-volume units (LVUs) due to decreased procedure and device familiarity. AIM:The aim of this study was to compare ERCP-NA training, safety, and HCIR relations...

journal_title：Digestive diseases and sciences

authors： Keswani RN,Malpas P,Lynch SE,Coté GA

更新日期：2016-03-01 00:00:00

abstract：:This study was undertaken to investigate the effect of ingestion of 80 g Vivonex on gallbladder volume, plasma cholecystokinin (CCK), and pancreatic polypeptide (PP) in eight healthy volunteers and to compare the results with those obtained after ingestion of 60 ml corn oil. Gallbladder volumes were measured by ultras...

journal_title：Digestive diseases and sciences

authors： Hopman WP,de Jong AJ,Rosenbusch G,Jansen JB,Lamers CB

更新日期：1987-01-01 00:00:00

abstract：AIMS:The purpose of this retrospective study was to assess clinical outcomes of endoscopic bougie dilation of esophageal strictures after radiation therapy for head and neck cancer, and to assess the risk factors which affect the treatment success. METHODS:Thirty-one patients with esophageal stricture due to radiation...

journal_title：Digestive diseases and sciences

authors： Tuna Y,Koçak E,Dinçer D,Köklü S

更新日期：2012-02-01 00:00:00

abstract：:Ehlers-Danlos syndrome (EDS) type IV is an autosomal dominant connective tissue disease caused by mutations in the type III collagen gene resulting in extreme tissue fragility. Affected individuals are at risk of dramatic and often fatal complications, mostly spontaneous arterial, uterine, or colonic ruptures. Phenoty...

journal_title：Digestive diseases and sciences

authors： Gelbmann CM,Köllinger M,Gmeinwieser J,Leser HG,Holstege A,Schölmerich J

更新日期：1997-08-01 00:00:00

abstract：:Fructose and lactose malabsorption are characterized by impaired duodenal fructose transport or by the deficiency of mucosal lactase, respectively. As a consequence, the nonabsorbed saccharides reach the colon, where they are broken down by bacteria to short fatty acids, CO2, and H2. Bloating, cramps, osmotic diarrhea...

journal_title：Digestive diseases and sciences

authors： Ledochowski M,Widner B,Sperner-Unterweger B,Propst T,Vogel W,Fuchs D

更新日期：2000-07-01 00:00:00

abstract：:Diagnosis of severe fibrosis (stages III and IV) in hepatitis C has clinical implications. Our objective was to distinguish independent predictors of severe fibrosis and use them to identify patients with severe fibrosis without a liver biopsy. One hundred ninety-nine hepatitis C patients were included in the initial ...

journal_title：Digestive diseases and sciences

authors： Metwally MA,Zein CO,Zein NN

更新日期：2007-02-01 00:00:00