Elemental diet stimulates gallbladder contraction and secretion of cholecystokinin and pancreatic polypeptide in man.

abstract：BACKGROUND:Enhanced cell expression of MAdCAM-1 is critical in tissue recruitment of lymphocytes in response to stimuli expressing the α4β7 integrin. MAdCAM-1 is well characterized in gut mucosa with emerging evidence of hepatic expression. AIMS:(i) Compare quantitative/semi-quantitatively MAdCAM-1 expression in relat...

journal_title：Digestive diseases and sciences

authors： Ala A,Brown D,Khan K,Standish R,Odin JA,Fiel MI,Schiano TD,Hillan KJ,Rahman SA,Hodgson HJ,Dhillon AP

更新日期：2013-09-01 00:00:00

abstract：:To investigate the colonic adenoma-adenocarcinoma progression sequence, DNA ploidy analysis was performed on hyperplastic polyps to adenocarcinomas. DNA ploidy data were then compared with immunocytochemical staining for proliferating cell nuclear antigen (PCNA). In hyperplastic polyps to villous adenomas, all cases w...

journal_title：Digestive diseases and sciences

authors： Tomita T

更新日期：1995-05-01 00:00:00

abstract：:Nutrients in the lumen of the small intestine may cause the release of enteric hormones which directly or indirectly stimulate intestinal mucosal growth. Male Sprague-Dawley rats with either an intact small bowel or following jejunal resection were maintained on total parenteral nutrition (TPN). C-terminal octapeptide...

journal_title：Digestive diseases and sciences

authors： Weser E,Bell D,Tawil T

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND AND AIM:Simultaneous dilatation of the common bile duct and pancreatic duct, "double-duct sign" (DDS), is an ominous finding concerning for pancreaticobiliary malignancy. Little evidence exists to guide the initial evaluation and subsequent follow-up for patients with DDS in the absence of jaundice or focal ...

journal_title：Digestive diseases and sciences

authors： Cohen J,Sawhney MS,Pleskow DK,Chuttani R,Patel NJ,Sheridan J,Berzin TM

更新日期：2014-09-01 00:00:00

abstract：:Segments of rat ileum and colon were infused in vivo to test if 0.1 M lactate, 10(-4) M H+, or both altered mucosal structure and function. In the first series of experiments, lactate concentration was kept at 0.1 M while H+ was varied from 10(-4) to 10(-7) M. Lactate and 10(-4) M H+ in the colon, and lactate and 10(-...

journal_title：Digestive diseases and sciences

authors： Saunders DR,Sillery J

更新日期：1982-01-01 00:00:00

abstract：:The pathophysiology of constipation after rectopexy remains unclear: acquired anorectal dysfunction or preoperative colonic state are, by turns, the supposed culprit. The aim of this prospective study was to characterize the colorectal motility abnormalities encountered after such a surgical procedure. Twelve patients...

journal_title：Digestive diseases and sciences

authors： Siproudhis L,Ropert A,Gosselin A,Bretagne JF,Heresbach D,Raoul JL,Gosselin M

更新日期：1993-10-01 00:00:00

abstract：:In the pathogenesis of gastroesophageal reflux disease (GERD), gastric acid is considered to be one of the most important factors, but little is known about the degree of gastric acid secretion in GERD patients. In this study, we evaluated it in GERD patients and control subjects by 24-h intragastric pH, and serologic...

journal_title：Digestive diseases and sciences

authors： Shimatani T,Inoue M,Harada N,Horikawa Y,Nakamura M,Tazuma S

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Current genetic research of nonalcoholic steatohepatitis (NASH) cirrhosis is limited by our ability to accurately identify cases on a large scale. Our objective was to develop and validate an electronic health record (EHR) algorithm to accurately identify cases of NASH cirrhosis in the EHR. METHODS...

journal_title：Digestive diseases and sciences

authors： Danford CJ,Lee JY,Strohbehn IA,Corey KE,Lai M

更新日期：2020-06-13 00:00:00

abstract：:Four patients with cold urticaria and six control subjects were studied. Gastric acid output was measured for 1 hr before and 1 hr after the immersion of both hands in ice cold water. The mean acid output fell in the control group by 16.3%. Acid output in the cold urticaria patients rose in each case following the col...

journal_title：Digestive diseases and sciences

authors： Lass N,Doron O,Gilat T

更新日期：1980-07-01 00:00:00

abstract：BACKGROUND:Restoring normal fecal flora through intestinal microbiota transplantation (IMT) was successful in curing recurrent Clostridium difficile infection (CDI). However, only a few cases have been reported of IMT being utilized for the treatment of severe or fulminant CDI. AIM:Is IMT a simple and effective treatm...

journal_title：Digestive diseases and sciences

authors： Zainah H,Hassan M,Shiekh-Sroujieh L,Hassan S,Alangaden G,Ramesh M

更新日期：2015-01-01 00:00:00

abstract：:There is a growing body of experimental and clinical evidence to suggest that oral or rectal administration of 5-ASA or 5-ASA conjugates is associated with significant adverse side effects including pancreatitis, hepatitis, and renal toxicity. The objective of this study was to assess the ability of 5-ASA to interact ...

journal_title：Digestive diseases and sciences

authors： Grisham MB,Ware K,Marshall S,Yamada T,Sandhu IS

更新日期：1992-09-01 00:00:00

abstract：:Patients with gallstone disease have impaired gallbladder motility. Prostaglandins are thought to be important mediators of gallbladder hypomotility. We assessed the effect of aspirin, a prostaglandin inhibitor on gallbladder resting volume and ejection fraction according to a double-blind study protocol in 20 healthy...

journal_title：Digestive diseases and sciences

authors： Das A,Baijal SS,Saraswat VA

更新日期：1995-08-01 00:00:00

abstract：:If an effective hepatic assist system existed, it could serve as a bridge to transplantation. Most of the patients waiting for liver transplantation have chronic liver insufficiency but are not in hepatic coma. Various hepatic assist systems have been used to salvage patients with acute liver insufficiency. Most attem...

journal_title：Digestive diseases and sciences

authors： Takahashi T,Malchesky PS,Nosé Y

更新日期：1991-09-01 00:00:00

abstract：OBJECTIVE:The regulation of apoptosis of intestinal mucosal cells is important in maintenance of normal intestinal physiology. SUMMARY:Sphingosine-1-phosphate (S1P) has been shown to play a critical role in cellular protection to otherwise lethal stimuli in several nonintestinal tissues. METHODS:The current study det...

journal_title：Digestive diseases and sciences

authors： Greenspon J,Li R,Xiao L,Rao JN,Marasa BS,Strauch ED,Wang JY,Turner DJ

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Ulcerative colitis (UC) is a chronic condition and the most common form of inflammatory bowel disease. The goal of standard treatment is mainly to induce and maintain remission with anti-inflammatory, immunosuppressive agents, and/or colectomy. Fecal microbiota transplantation (FMT) has been used successfull...

journal_title：Digestive diseases and sciences

authors： Tian Z,Liu J,Liao M,Li W,Zou J,Han X,Kuang M,Shen W,Li H

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:S-isomer (S) pantoprazole is known to be more effective and less dependent on cytochrome 2C19 than R-isomer (R)-pantoprazole. AIM:The purpose of this study was to compare the efficacy and safety of S-pantoprazole 20 mg versus pantoprazole 40 mg for treatment of reflux esophagitis. METHODS:This multi-center...

journal_title：Digestive diseases and sciences

authors： Cho YK,Choi MG,Bak YT,Rhee PL,Kim SG,Jung HY,Seol SY

更新日期：2012-12-01 00:00:00

abstract：:Sodium butyrate is a well-recognized differentiating agent inducing alkaline phosphatase activity, one of the epithelial differentiation markers. When IEC6 cells, a nontransformed, small intestinal epithelial cell line, were cultured with butyrate, this substrate induced alkaline phosphate activity in a time- and dose...

journal_title：Digestive diseases and sciences

authors： Fukushima K,Sasaki I,Hasegawa H,Takahashi K,Naito H,Funayama Y,Matsuno S

更新日期：1998-05-01 00:00:00

abstract：:In some patients, proton pump inhibitors do not abolish nocturnal gastric acidity and additional evening antisecretory medication may be required. In 16 subjects with chronic heartburn, 24-hr gastric and esophageal pH were measured at baseline and again after six days of 20 mg omeprazole alone at 08:00 hr followed by ...

journal_title：Digestive diseases and sciences

authors： Robinson M,Rodriguez-Stanley S,Ciociola AA,Filinto J,Zubaidi S,Miner PB Jr,Gardner JD

更新日期：2002-02-01 00:00:00

abstract：:Chemiluminescence (CL) analysis of monocytes and polymorphonuclear cells (PMNs) was performed on 13 patients with Crohn's disease (CD) and 10 healthy volunteers. The percentages of monocyte populations in mononuclear cells obtained from the patients with CD were greater than those from the healthy volunteers, but the ...

journal_title：Digestive diseases and sciences

authors： Kitahora T,Suzuki K,Asakura H,Yoshida T,Suematsu M,Watanabe M,Aiso S,Tsuchiya M

更新日期：1988-08-01 00:00:00

abstract：:Intestinal injury 4-48 hr after cytotoxic therapy (etoposide phosphate, 100 mg/kg body weight [bw], intravenously [i.v.]) was studied in rats using ligated intestinal loops. Chromium-51 ethylenediaminetetraacetic acid ((51)Cr-EDTA) and rubidium-86 chloride ((86)RbCl) were deposited intraluminally to determine the exte...

journal_title：Digestive diseases and sciences

authors： Abel E,Ekman T,Warnhammar E,Hultborn R,Jennische E,Lange S

更新日期：2005-09-01 00:00:00

abstract：:Among 56 cases who presented to Kanto-Teishin Hospital complaining of bloody diarrhea or considerable hematochezia of acute onset, 8 cases (14.3%) were considered due to colitis associated with oral ampicillin therapy. The bloody diarrhea, often with abdominal cramps, began 2-7 days after starting the treatment. The d...

journal_title：Digestive diseases and sciences

authors： Sakurai Y,Tsuchiya H,Ikegami F,Funatomi T,Takasu S,Uchikoshi T

更新日期：1979-12-01 00:00:00

abstract：:The role of nitric oxide in intestinal fluid and electrolyte secretion depends upon whether the conditions under study are physiological or pathophysiological. In physiological conditions, endogenous nitric oxide seems to be a proabsorptive molecule, based on the findings that nitric oxide synthase inhibitors reverse ...

journal_title：Digestive diseases and sciences

authors： Izzo AA,Mascolo N,Capasso F

更新日期：1998-08-01 00:00:00

abstract：:Mutations in the gene encoding the CYP2C-19 enzyme for PPI metabolism have been shown to enhance the chance for a cure in a H. pylori-positive patients using a two-week dual-therapy regimen involving omeprazole and amoxicillin. However, the impact of CYP2C-19 genetic polymorphism on eradication rates of a one-week tri...

journal_title：Digestive diseases and sciences

authors： Miwa H,Misawa H,Yamada T,Nagahara A,Ohtaka K,Sato N

更新日期：2001-11-01 00:00:00

abstract：:The interaction of [35S]methionine with hepatic tRNA in normal, carcinogen-treated, and partially hepatectomized rats was studied. tRNA was preferentially labeled following [35S]methionine (1.6 mCi, 25 mg/kg body wt) administration by intraperitoneal injection. The extent of [35S]methionine-tRNA interaction was impair...

journal_title：Digestive diseases and sciences

authors： Kanduc D,Quagliariello E

更新日期：1991-07-01 00:00:00

abstract：:The effects of cisapride on upper gut motility were studied in seven healthy volunteers by means of a novel intraluminal electromyographic technique in a placebo-controlled study. In the interdigestive state, cisapride (10 mg intravenous bolus injection) markedly increased the number of spike bursts. The most obvious ...

journal_title：Digestive diseases and sciences

authors： Coremans G,Janssens J,Vantrappen G,Chaussade S,Ceccatelli P

更新日期：1988-12-01 00:00:00

abstract：:The effect of nutrients on small intestinal motility is controversial. Our aim was to analyze the effect of intraduodenal infusion of mixtures of nutrients of increasing caloric load, on intestinal motility. Studies were performed in dogs with a duodenal cannula. Isosmolar infusions of saline, 0.5, 2, and 4 kcal/min w...

journal_title：Digestive diseases and sciences

authors： Defilippi C

更新日期：2003-08-01 00:00:00

abstract：:Gastric emptying scintigraphy (GES) is usually performed for up to 2 hr to measure the gastric emptying (GE) of solids. Symptomatic patients, however, may have borderline results at 2 hr, making it difficult to determine whether a gastric motor disorder is present. The aim of this study was to assess whether extending...

journal_title：Digestive diseases and sciences

authors： Guo JP,Maurer AH,Fisher RS,Parkman HP

更新日期：2001-01-01 00:00:00

abstract：:Our aim was to investigate whether there are changes in permeability to sucrose in asymptomatic Helicobacter pylori gastritis. Nineteen asymptomatic subjects with Helicobacter pylori-associated gastritis with no or mild mucosal atrophy and 19 age- and sex-matched normal controls were studied by peroral load of sucrose...

journal_title：Digestive diseases and sciences

authors： Borch K,Sjöstedt C,Hannestad U,Söderholm JD,Franzén L,Mårdh S

更新日期：1998-04-01 00:00:00

abstract：:We have previously reported impressive results in using a gonadotropin-releasing hormone analog, leuprolide acetate (Lupron), in the treatment of moderate to severe symptoms (especially abdominal pain and nausea) in patients with functional bowel disease (FBD). Pain is the hallmark of patients with FBD, and there is n...

journal_title：Digestive diseases and sciences

authors： Mathias JR,Clench MH,Abell TL,Koch KL,Lehman G,Robinson M,Rothstein R,Snape WJ

更新日期：1998-06-01 00:00:00

abstract：:Minimal hepatic encephalopathy (MHE) describes patients with chronic liver disease or cirrhosis who have no clinical symptoms of brain dysfunction but perform worse on psychometric tests compared with healthy subjects. The pathogenesis of hepatic encephalopathy is controversial although ammonia has been found to induc...

journal_title：Digestive diseases and sciences

authors： Malaguarnera M,Greco F,Barone G,Gargante MP,Malaguarnera M,Toscano MA

更新日期：2007-11-01 00:00:00