The serotonin transporter polymorphism rs25531 is associated with irritable bowel syndrome.

abstract：:Nine patients with concurrent myelodysplastic syndrome (MDS) and inflammatory bowel disease (IBD) were examined. Median age at diagnosis of these patients was similar to the usual age of patients at diagnosis of IBD only. There was a strong predominance of Crohn's disease (seven of nine cases), with an unusually high ...

journal_title：Digestive diseases and sciences

authors： Wang Z,Zhou Y,Liu Y

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Eradication therapies for Helicobacter pylori infection are advancing as new acid inhibitory reagents approved. The aim of this study was to assess the efficacy and safety of vonoprazan-based triple treatment. MATERIALS AND METHODS:Triple therapy with vonoprazan and two antibiotics (amoxicillin and clarithr...

journal_title：Digestive diseases and sciences

authors： Tanabe H,Ando K,Sato K,Ito T,Goto M,Sato T,Fujinaga A,Kawamoto T,Utsumi T,Yanagawa N,Ichiishi E,Otake T,Kohgo Y,Nomura Y,Ueno N,Sugano H,Kashima S,Moriichi K,Fujiya M,Okumura T

更新日期：2017-11-01 00:00:00

abstract：:Transverse myelitis (TM) as a manifestation of an autoimmune disorder is relatively rare. In Sjogren's syndrome (SS), the occurrence of TM is remarkably uncommon. Only three cases have been reported associated with primary biliary cirrhosis (PBC). Here we report the fourth case of TM occurring in association with SS a...

journal_title：Digestive diseases and sciences

authors： Anantharaju A,Baluch M,Van Thiel DH

更新日期：2003-04-01 00:00:00

abstract：:The aim of the study was to determine inter- and intrapatient variation of Helicobacter pylori strains based on genomic fingerprinting and cagA (cytotoxin-associated gene A) status. Ten bacterial colonies from each of 10 patients with gastric cancer (GC), 10 with duodenal ulcer (DU), and 10 with gastritis (GI) were us...

journal_title：Digestive diseases and sciences

authors： Enroth H,Nyrén O,Engstrand L

更新日期：1999-01-01 00:00:00

abstract：:As chronic liver disease progresses, an imbalance occurs between synthesis and breakdown of extracellular matrix (ECM). Matrix metalloproteinases (MMPs) are involved in degrading ECM while tissue inhibitors of metalloproteinases (TIMPs) prevent their fibrolytic action. We determined if plasma levels of MMP-2, TIMP-1 a...

journal_title：Digestive diseases and sciences

authors： Walsh KM,Timms P,Campbell S,MacSween RN,Morris AJ

更新日期：1999-03-01 00:00:00

abstract：:The preoperative determination of the localization of a small insulinoma is sometimes difficult using routine imaging techniques. We have used the selective arterial calcium injection (SACI) test to determine the location of the tumor preoperatively. The pathophysiologic basis of the SACI test is based on the responsi...

journal_title：Digestive diseases and sciences

authors： Kato M,Doi R,Imamura M,Okada N,Shimada Y,Hosotani R,Miyazaki JI

更新日期：1998-11-01 00:00:00

abstract：:Suspected risk factors for adenocarcinoma of the small bowel in Crohn's disease include surgically excluded small bowel loops, chronic fistulous disease, and male sex. Review of all seven University of Chicago cases failed to confirm any suspected risk factor. A case-control study was performed to identify possible al...

journal_title：Digestive diseases and sciences

authors： Lashner BA

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Tyrosine phosphorylation and dephosphorylation by protein tyrosine kinases and phosphatases (PTPs), respectively, play crucial roles in cellular signal transduction. Protein phosphatase non-receptor type 11 (PTPN11) is a positive signaling PTP that activates RAS and ERK signaling. Also, the PTPN11 binds with...

journal_title：Digestive diseases and sciences

authors： Kim JS,Shin OR,Kim HK,Cho YS,An CH,Lim KW,Kim SS

更新日期：2010-06-01 00:00:00

abstract：:Published clinical trials (N = 56) of antisecretory drugs in the treatment of benign gastric ulcer were reviewed. Composite healing rates for various drug regimens were calculated using a method previously described for duodenal ulcer. Healing rates were compared with data on suppression of intragastric acidity to see...

journal_title：Digestive diseases and sciences

authors： Howden CW,Jones DB,Peace KE,Burget DW,Hunt RH

更新日期：1988-05-01 00:00:00

abstract：:Leptin is a 16-kDa nonglycosylated protein primarily secreted from the adipocytes of white fat; minor levels of regulated leptin expression also occurs at other sites such as placenta, skeletal muscle, the stomach fundus, and culture-activated hepatic stellate cells (HSCs). Leptin is primarily involved in the regulati...

journal_title：Digestive diseases and sciences

authors： Bethanis SK,Theocharis SE

更新日期：2006-10-01 00:00:00

abstract：:The treatment options for palliating malignant gastroduodenal obstruction include open gastrojejunostomy (OGJ), laparoscopic gastrojejunostomy (LGJ), and endoscopic stenting (ES). The aim of this study was to compare the clinical outcomes and costs among ES, OGJ, and LGJ in patients who present with gastroduodenal obs...

journal_title：Digestive diseases and sciences

authors： Siddiqui A,Spechler SJ,Huerta S

更新日期：2007-01-01 00:00:00

abstract：AIMS:To determine whether temporary fecal diversion for refractory colonic and/or perianal Crohn's disease can lead to clinical remission and restoration of intestinal continuity after optimization of medical therapy. METHODS:We retrospectively reviewed our prospectively maintained database of patients treated at the ...

journal_title：Digestive diseases and sciences

authors： Bafford AC,Latushko A,Hansraj N,Jambaulikar G,Ghazi LJ

更新日期：2017-08-01 00:00:00

abstract：:In vitro and in vivo experiments were carried out with medium-chain glycerides. In vitro, cholesterol gallstones were rapidly dissolved by medium-chain glycerides; control experiments with saline solution failed to modify the size of the stones. In vivo, medium-chain glycerides were instilled through an intraductal tu...

journal_title：Digestive diseases and sciences

authors： Uribe M,Uscanga L,Farca S,Sanjurjo JL,LaGarriga J,Ortíz JH

更新日期：1981-07-01 00:00:00

abstract：BACKGROUND:While the short-term benefits of exclusive enteral nutrition (EEN) for induction of remission in children with Crohn's disease (CD) are well documented, the longer-term outcomes are less clear. AIM:This retrospective study aimed to ascertain the outcomes for up to 24 months following EEN in a group of child...

journal_title：Digestive diseases and sciences

authors： Lambert B,Lemberg DA,Leach ST,Day AS

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:No previous studies have compared cytology obtained under endoscopic transpapillary gallbladder drainage (ETGD) and EUS-guided fine needle aspiration (EUS-FNA) for thick-walled gallbladders. AIM:The present study investigated the diagnostic yield of bile cytology under ETGD and EUS-FNA for gallbladder tumor...

journal_title：Digestive diseases and sciences

authors： Ogura T,Kurisu Y,Masuda D,Imoto A,Onda S,Kamiyama R,Hayashi M,Mohamed M,Uchiyama K,Higuchi K

更新日期：2014-08-01 00:00:00

abstract：:Minimal lesions of the small bowel are mucosal changes characterized by an increased number of intraepithelial lymphocytes (with or without crypt hyperplasia) and normal villous architecture. Such changes are associated with a wide spectrum of conditions, ranging from food intolerances to infections, and from drugs to...

journal_title：Digestive diseases and sciences

authors： Volta U,Caio G,Ghirardi C,Lungaro L,Mansueto P,Carroccio A,De Giorgio R

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND AND STUDY AIMS:Bowel-cleansing studies are frequently underpowered, poorly designed, and with subjective assessments. Consensus on tolerability of the bowel-cleansing agents is thus lacking. This study developed and validated a bowel-preparation tolerability questionnaire and used it to assess the tolerabili...

journal_title：Digestive diseases and sciences

authors： Lawrance IC,Willert RP,Murray K

更新日期：2013-04-01 00:00:00

abstract：:In this study, we examined the effect of rebamipide, a mucoprotective drug, on gastric ulcer healing in Mongolian gerbils infected with H. pylori. Male Mongolian gerbils were inoculated with H. pylori or vehicle alone 12 hr after the production of an acetic acid-induced gastric ulcer. On day 5, the gerbils inoculated ...

journal_title：Digestive diseases and sciences

authors： Watanabe T,Higuchi K,Hamaguchi M,Tanigawa T,Wada R,Tominaga K,Fujiwara Y,Arakawa T

更新日期：2002-07-01 00:00:00

abstract：:The effect of ischemia-reperfusion and 48-hr fasting on apoptosis was characterized in rat gastric mucosa and compared to small intestinal mucosa. Under halothane anesthesia, the celiac artery or superior mesenteric artery in the rat was occluded for 60 min followed by reperfusion. Occlusion of the celiac artery reduc...

journal_title：Digestive diseases and sciences

authors： Fukuyama K,Iwakiri R,Noda T,Kojima M,Utsumi H,Tsunada S,Sakata H,Ootani A,Fujimoto K

更新日期：2001-03-01 00:00:00

abstract：:Concordance between gram-negative enteric and other toxin-producing bacteria in blood and stool culture, endotoxin (lipopolysaccharide), and interleukin-6 (IL-6) was measured in 60 preterm infants (600-1600 g) as a clinical index in neonatal necrotizing enterocolitis (NEC). E. coli, Klebsiella, Enterobacter, and Clost...

journal_title：Digestive diseases and sciences

authors： Duffy LC,Zielezny MA,Carrion V,Griffiths E,Dryja D,Hilty M,Rook C,Morin F 3rd

更新日期：1997-02-01 00:00:00

abstract：:The synthetic substrate cholyl-PABA, developed by conjugating cholic acid with paraaminobenzoic acid, is hydrolyzed by the bacterial enzyme cholyl hydrolase to release free PABA. This study aimed to evaluate whether quantitating urinary excretion of PABA after oral administration of cholyl-PABA can detect small intest...

journal_title：Digestive diseases and sciences

authors： Bardhan PK,Feger A,Kogon M,Muller J,Gillessen D,Beglinger C,Gyr N

更新日期：2000-03-01 00:00:00

abstract：:The question of whether alcohol drinking is a risk factor for fatty liver as shown by ultrasonography was investigated by both cross-sectional and longitudinal approaches in Japanese undergoing a health checkup. In this cross-sectional study, 32,438 males (49.0 +/- 11.9 years old) and 31,009 females (48.2 +/- 11.6 yea...

journal_title：Digestive diseases and sciences

authors： Yamada T,Fukatsu M,Suzuki S,Yoshida T,Tokudome S,Joh T

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Approximately 233,898 individuals in the Veterans Affairs healthcare network are hepatitis C virus (HCV)-infected, making the Veterans Affairs the single largest provider of HCV care in the USA. Direct-acting antiviral treatment regimens for HCV offer high cure rates. However, these medications pose an enorm...

journal_title：Digestive diseases and sciences

authors： Maier MM,Zhou XH,Chapko M,Leipertz SL,Wang X,Beste LA

更新日期：2018-06-01 00:00:00

abstract：:Somatostatin inhibits colonic ion secretion in animal models and cultured intestinal cell lines via somatostatin receptor subtype 2 and subtype 1, respectively. In a recent in vitro ion transport study of the human colon, somatostatin was shown to stimulate short-circuit current, a measure of electrogenic ion transpor...

journal_title：Digestive diseases and sciences

authors： Hope N,Butt G,Ross I,Warhurst G,Arn M,Grigor M,Lubcke R,Barbezat GO

更新日期：2001-11-01 00:00:00

abstract：:Alcoholic liver disease (ALD) is characterized by elevated serum IgA concentrations, the presence of circulating immune complexes containing IgA, and IgA deposits along sinusoids in the liver. When combined with the presupposed IgA-clearance function of the liver, a causal association between IgA abnormalities and the...

journal_title：Digestive diseases and sciences

authors： van de Wiel A,Valentijn RM,Schuurman HJ,Daha MR,Hené RJ,Kater L

更新日期：1988-06-01 00:00:00

abstract：:In a retrospective study, 50 patients with obvious necrotizing pancreatitis (NP) were allocated in four groups according to the morphological aspects of the necrosis. Appearance of ascite (N1), extrapancreatic spread of necrosis towards neighboring organs (N2), a large amount of necrosis (N3), and infected necrosis (N...

journal_title：Digestive diseases and sciences

authors： Le Mée J,Janny S,Sauvanet A,Werner P,Belghiti J

更新日期：1997-08-01 00:00:00

abstract：:Technological developments have greatly promoted interest in the use of computer systems for recording findings and images at endoscopy and creating databases. The aim of this study was to develop a comprehensive WHO-approved code system for gastrointestinal endoscopic terminology. The International Classification of ...

journal_title：Digestive diseases and sciences

authors： Groenen MJ,Hirs W,Becker H,Kuipers EJ,Van Berge Henegouwen GP,Fockens P,Ouwendijk RJ

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Proton pump inhibitors (PPIs) may reduce the risk of esophageal adenocarcinoma (EAC) in patients with Barrett's esophagus. PPIs are prescribed for virtually all patients with Barrett's esophagus, irrespective of the presence of reflux symptoms, and represent a de facto chemopreventive agent in this populatio...

journal_title：Digestive diseases and sciences

authors： Sharaiha RZ,Freedberg DE,Abrams JA,Wang YC

更新日期：2014-06-01 00:00:00

abstract：:Neurotensin-like immunoreactivity (NTLI) is released into the circulation following a meal. However, the factors influencing its degradation and metabolism are uncertain, but it is presumed that the kidneys and liver are involved. This study has determined the release of NTLI after a liquid fat meal (200 ml 20% Intral...

journal_title：Digestive diseases and sciences

authors： Eaves ER,Hansky J

更新日期：1987-01-01 00:00:00

abstract：:Intestinal mast cells are thought to contribute to the mucosal inflammation in ulcerative colitis and Crohn's disease through release of inflammatory mediators. Since sulfasalazine and its metabolite 5-aminosalicylic acid are effective therapeutic agents in inflammatory bowel disease and have been shown to inhibit gen...

journal_title：Digestive diseases and sciences

authors： Fox CC,Moore WC,Lichtenstein LM

更新日期：1991-02-01 00:00:00