Abstract：
BACKGROUND:No previous studies have compared cytology obtained under endoscopic transpapillary gallbladder drainage (ETGD) and EUS-guided fine needle aspiration (EUS-FNA) for thick-walled gallbladders. AIM:The present study investigated the diagnostic yield of bile cytology under ETGD and EUS-FNA for gallbladder tumors. METHODS:A total of 69 patients were diagnosed as having gallbladder wall thickening. Among these patients, 28 patients were diagnosed by clinical follow-up, solely by imaging such as computed tomography or by histological examination of surgical specimens. The remaining 41 patients underwent ETGD and/or EUS-FNA. In these 41 patients, the clinical data collected included gender, age, diameter of gallbladder wall, site of gallbladder wall thickening, final diagnosis, adverse events, and diagnostic yield of ETGD and EUS-FNA. RESULTS:Cyto-histological diagnosis with EUS-FNA was higher than that with ETGD, with a sensitivity of 100 versus 71%, specificity of 100 versus 94%, and accuracy of 100 versus 88%, respectively, in the two groups. In addition, the sampling adequacy of EUS-FNA was 100%. Adverse events were seen in five patients in the ETGD group (mild pancreatitis), although no adverse events were seen in the EUS-FNA group (P = 0.08). CONCLUSION:Our results suggest that EUS-FNA can be safely performed for the diagnosis of gallbladder lesions. Further, this procedure may be the diagnostic method of choice over cytology of bile juice obtained via ETGD to obtain histological evidence of gallbladder cancer.
journal_name
Dig Dis Scijournal_title
Digestive diseases and sciencesauthors
Ogura T,Kurisu Y,Masuda D,Imoto A,Onda S,Kamiyama R,Hayashi M,Mohamed M,Uchiyama K,Higuchi Kdoi
10.1007/s10620-014-3100-zsubject
Has Abstractpub_date
2014-08-01 00:00:00pages
1917-24issue
8eissn
0163-2116issn
1573-2568journal_volume
59pub_type
临床试验,杂志文章abstract：:The possibility of obtaining oral desensitization in patients with food allergy is still a matter of debate. We decided to evaluate the safety and efficacy of standardized protocols for oral desensitization with the most common food allergens. Forty-two children (ages up to 16 years) diagnosed as affected by food alle...
journal_title：Digestive diseases and sciences
pub_type： 临床试验,杂志文章
doi：10.1007/s10620-006-9245-7
更新日期：2007-07-01 00:00:00
abstract：BACKGROUND AND AIM:Second harmonic generation (SHG) is a novel imaging technology that could provide optical biopsy during endoscopy with advantages over current technology. SHG has the unique ability to evaluate the amount of extracellular matrix collagen protein and its alignment. METHODS:Hematoxylin- and eosin-stai...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-014-3121-7
更新日期：2014-07-01 00:00:00
abstract：BACKGROUND:The risk of pancreatic cancer is elevated among people with new-onset diabetes (NOD). Based on Rochester Epidemiology Project Data, the Enriching New-Onset Diabetes for Pancreatic Cancer (END-PAC) model was developed and validated. AIMS:We validated the END-PAC model in a cohort of patients with NOD using r...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-020-06139-z
更新日期：2021-01-01 00:00:00
abstract：:The original version of the article unfortunately contained an error in the unit used for 'Distance of propagation'. The distance of propagation should be in the unit 'cm' rather than 'mm' throughout the manuscript. ...
journal_title：Digestive diseases and sciences
pub_type： 已发布勘误
doi：10.1007/s10620-020-06524-8
更新日期：2020-08-08 00:00:00
abstract：:Suspected risk factors for adenocarcinoma of the small bowel in Crohn's disease include surgically excluded small bowel loops, chronic fistulous disease, and male sex. Review of all seven University of Chicago cases failed to confirm any suspected risk factor. A case-control study was performed to identify possible al...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01296557
更新日期：1992-08-01 00:00:00
abstract：:A classification of gastrointestinal motility disorders is offered based upon the type of disorder in transit (delay or acceleration), and the region of the gastrointestinal tract affected. Specific abnormalities of myoelectrical patterns are identified when possible and related to disturbances in transit in the stoma...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章,评审
doi：10.1007/BF01295987
更新日期：1986-09-01 00:00:00
abstract：:On the basis of previous studies in our laboratory we postulated that the ethanol-induced alteration in jejunal morphology was the result of its effect on the microcirculation. The present study was undertaken to examine the validity of this hypothesis. Accordingly, the effects of intraluminal ethanol perfusion (3.0 a...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01311730
更新日期：1983-11-01 00:00:00
abstract：BACKGROUND:Computed tomography (CT) and magnetic resonance (MR) enterography are now widely used to diagnose and monitor Crohn's disease. AIM:We sought to assess the use of enterography for management of inflammatory bowel disease (IBD) in our medical center. METHODS:We performed a retrospective review of all patient...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-013-2964-7
更新日期：2014-04-01 00:00:00
abstract：:Up to 60% of patients with IBS have lowered perception thresholds in the rectum to balloon distension. The current study sought to test the hypothesis that IBS patients with normal perception thresholds in the rectum show hypersensitivity of afferent pathways in the sigmoid colon. Eleven healthy normal subjects and ei...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1018817132213
更新日期：1997-06-01 00:00:00
abstract：:In this study, two antiallergic compounds, betamethasone and disodium cromoglycate were tested in an animal model of intestinal anaphylaxis. Rats, immunized with Nippostrongylus brasiliensis, were challenged intravenously with whole worm antigen or saline. Antigen challenge resulted in significant abnormalities: epith...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01299863
更新日期：1992-11-01 00:00:00
abstract：:Biliary mucin was isolated from human hepatic bile, and its induced effects on the appearance time of cholesterol monohydrate crystals (nucleation time) and on the precipitation of calcium carbonate were studied in vitro to examine the possible significance of mucin for ductular gallstone formation. Mucin was isolated...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01295919
更新日期：1993-05-01 00:00:00
abstract：:We conducted a double-blind, placebo-controlled study to evaluate the effects of ranitidine on intragastric pH and upper gastrointestinal tract bleeding in severe head injury patients. Within 24 hr of the precipitating trauma, 34 adults with Glasgow coma scale scores < or = 10 were randomized to a 6.25 mg/hr ranitidin...
journal_title：Digestive diseases and sciences
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF02064385
更新日期：1995-03-01 00:00:00
abstract：:Obesity and diet affect the incidence and severity of various types of cancer, including colon cancer. It is not known whether obesity, independent of diet, is a risk factor for colon adenocarcinoma. We used azoxymethane (AOM) to induce colon cancer in mature genetically obese male Zucker rats (fa/fa) on low-fat crude...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1005560621722
更新日期：2000-05-01 00:00:00
abstract：:Several plant-derived polysaccharides have been shown to have anti-inflammatory activity in animal models. Ambrotose complex and Advanced Ambrotose are dietary supplements that include aloe vera gel, arabinogalactan, fucoidan, and rice starch, all of which have shown such activity. This study was designed to evaluate ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-009-0848-7
更新日期：2010-05-01 00:00:00
abstract：:The peroxisome proliferator-activated receptor gamma (PPARgamma) is a nuclear receptor highly expressed in the colon and playing an anti-inflammatory role through inhibition of the NF-kappaB pathway. Toll-like receptor 4 (TLR4) has been known to mediate LPS-induced cellular signaling through activation of NF-kappaB pa...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-006-3193-0
更新日期：2006-04-01 00:00:00
abstract：:Helicobacter pylori infection has been linked with gastric carcinoma. Epithelial cell proliferation is an indicator of cancer risk. The aim of this study was to assess gastric epithelial cell proliferation before and after eradication therapy and to assess the efficacy of treatment of H. pylori infection using lanzopr...
journal_title：Digestive diseases and sciences
pub_type： 临床试验,杂志文章
doi：10.1007/BF02212681
更新日期：1995-08-01 00:00:00
abstract：:To test the role of immune reactivity in the pathogenesis of hepatitis C, serum soluble immune factors were measured in a cohort of 57 patients with chronic hepatitis C, and in 20 healthy subjects. Levels of interleukin-1 beta, granulocyte-macrophage colony-stimulating factor, tumor necrosis factor-alpha, and interleu...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF02087671
更新日期：1994-11-01 00:00:00
abstract：BACKGROUND:Assessment and quantification of actual liver function is crucial in patients with chronic liver disease to monitor disease progression and predict individual prognosis. Mathematical models, such as model for end-stage liver disease, are used for risk stratification of patients with chronic liver disease but...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-014-3250-z
更新日期：2014-12-01 00:00:00
abstract：:Solitary rectal ulcer syndrome (SRUS) is sufficiently uncommon that the clinician or general pathologist may lack familiarity with the disorder and may confuse it with other inflammatory bowel diseases. To evaluate the role of collagen staining in facilitating the differential diagnosis of SRUS, an initial open review...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01536986
更新日期：1988-11-01 00:00:00
abstract：:The gold standard for measuring gastric emptying is scintigraphy, either with digestible solids or liquids. Unfortunately, this method is expensive and of limited availability. An alternative could be to use radiopaque markers (ROMs). Our aim was to compare these two tests in healthy volunteers and in patients to see ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1026609808495
更新日期：1999-04-01 00:00:00
abstract：AIM:Several models of experimental ulcerative colitis have been previously reported. To date, only one model of Crohn's colitis that was induced by trinitrobenzene sulfonic acid has been described. MATERIALS AND METHODS:Twenty-one male albino rats were divided into three groups: group I: sham control group (n = 7), gr...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-011-1697-8
更新日期：2011-10-01 00:00:00
abstract：BACKGROUND AND AIMS:The present study aimed to identify the differential expressed genes that are related to acute pancreatitis. METHODS:Microarray datasets GSE109227 and GSE3644 were downloaded from the public database and analyzed to screen the genes. Afterward, integrated analysis of these genes were performed, inc...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-019-05928-5
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:Obesity and metabolic syndrome are risk factors for colorectal neoplasia (CRN). However, the association between metabolically healthy obese (MHO) or metabolically unhealthy non-obese (MUNO) status and the risk of CRN remains unclear. AIMS:We aimed to elucidate the association between MHO or MUNO status and...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-018-5239-5
更新日期：2018-11-01 00:00:00
abstract：:These studies were done to determine the effects of fluoride (F) on the structure and function of the canine gastric mucosa and the possible protective effects of 16,16-dimethyl-prostaglandin E2 (dmPGE2). A portion of the stomach with its vascular supply intact was mounted in a two-compartment chamber, one side of whi...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1018895207333
更新日期：1997-10-01 00:00:00
abstract：:The mechanism by which alcohol causes pancreatic damage is still largely unknown. One important contributory factor may be the endothelins, potent vasoconstricting endothelial-derived peptides. The aim of this study was to examine in vivo endothelin release from the pancreatic vascular endothelium after alcohol ingest...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1018845710446
更新日期：1998-05-01 00:00:00
abstract：UNLABELLED:The purpose of this study was to investigate and compare the specificity, sensitivity, and area under curve (AUC) of the lactulose/mannitol ratio, lactulose/creatinine ratio, and lactulose recovery and their diagnostic value for intestinal permeability assessment within the absorption lactulose/mannitol (L/M...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-007-0184-8
更新日期：2008-10-01 00:00:00
abstract：BACKGROUND:Interferon regulatory factor 9 (IRF9) acts as a negative regulator of sirtuin-1 (SIRT1) to participate in many diseases. However, the role of SIRT1 and IRF9 in hyperlipidemia acute pancreatitis associated with kidney injury is unclear. AIMS:To explore the function of SIRT1 and IRF9 in hyperlipidemia acute p...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-020-06331-1
更新日期：2020-05-28 00:00:00
abstract：:Tacrolimus, a relatively new therapeutic option for patients with corticosteroid-refractory Crohn's disease or ulcerative colitis, is a substrate for the apically directed efflux transporter P-glycoprotein (P-gp). Duodenal biopsy specimens obtained from a patient with corticosteroid-refractory Crohn's disease and with...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-005-3053-3
更新日期：2005-12-01 00:00:00
abstract：:Growing evidence suggests that complex gene and environment interactions underlie a number of diseases including chronic inflammatory diseases of the digestive system. The rapid advances in information and technology provide opportunities to discover the risks or etiology for a variety of disorders within individual p...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章,评审
doi：10.1007/s10620-005-3033-7
更新日期：2005-12-01 00:00:00
abstract：:Patients with previous gastric surgery for benign conditions are thought to be at increased risk for gastric cancer based on studies from Europe. Recommendations have been made to screen these patients repeatedly in order to detect early gastric cancers. We conducted a case-control study to estimate the risk in the Un...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01312941
更新日期：1984-08-01 00:00:00
