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Stevens-Johnson Syndrome and cholestatic hepatitis.

Abstract：

:Stevens-Johnson Syndrome (SJS) is a rare but severe dermatological condition that typically occurs after the ingestion of medications such as nonsteroidal drugs, antibiotics, and anticonvulsants. Extracutaneous manifestations of the syndrome can occur and may involve the conjunctiva, trachea, buccal mucosa, gastrointestinal tract, and genitourinary tract. Cholestatic liver disease, which may precede the skin manifestations of SJS, has been reported to occur in SJS, but the medical literature has only 10 case reports describing this phenomenon (1-9). We report the case of a 19-year-old female with SJS and cholestatic liver disease. A discussion of the underlying pathophysiology of SJS and its treatment follows.

journal_name

Dig Dis Sci

journal_title

Digestive diseases and sciences

authors

Morelli MS,O'Brien FX

doi

10.1023/a:1012351231143

subject

Has Abstract

pub_date

2001-11-01 00:00:00

pages

2385-8

issue

11

eissn

0163-2116

issn

1573-2568

journal_volume

46

pub_type

杂志文章,评审

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