What does pain or discomfort in irritable bowel syndrome mean?

abstract：:The distribution of tissue kallikrein (TK) and its plasma inhibitor, kallistatin in plasma and intestinal tissue, was studied in patients with active ulcerative colitis (UC) and Crohn's disease (CD). TK was localized to goblet cells and kallistatin to epithelial cells of normal human intestine. Both proteins are visua...

journal_title：Digestive diseases and sciences

authors： Stadnicki A,Mazurek U,Gonciarz M,Plewka D,Nowaczyk G,Orchel J,Pastucha E,Plewka A,Wilczok T,Colman RW

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Percutaneous endoscopic gastrostomy (PEG) is a commonly performed procedure for patients with severe dysphagia leading to malnutrition. Improved knowledge of risk factors for PEG-related complications might decrease patient discomfort and healthcare costs. AIM:The aim of the present study was to investigate...

journal_title：Digestive diseases and sciences

authors： Lee SP,Lee KN,Lee OY,Lee HL,Jun DW,Yoon BC,Choi HS,Kim SH

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Nonalcoholic fatty liver disease (NAFLD) is the number one cause of liver disease in the United States. The prevalence rates in African Americans (AA), while significantly lower than other ethnic groups with similar known risk factors, have been quoted as high as 24 %. We aim to determine if the pre...

journal_title：Digestive diseases and sciences

authors： Foster T,Anania FA,Li D,Katz R,Budoff M

更新日期：2013-08-01 00:00:00

abstract：:We evaluated the contribution of alcohol abuse to liver failure among patients undergoing liver transplantation by reviewing their records for alcohol consumption, hepatitis serology, and outcome. Anti-HCV was present in the serum of 42 patients (39%), while 35 had consumed more than 80 g/day of alcohol for at least 1...

journal_title：Digestive diseases and sciences

authors： Dhar S,Omran L,Bacon BR,Solomon H,Di Bisceglie AM

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND/AIMS:The purpose of this study is to explore the inhibition or activation effects of microRNA-146 B on the expression of PTP1B in gastric cancer cells. METHODS:The expressions of PTP1B and miR-146b in gastric cancer were detected by RT-qPCR. The effects of miR-146b on cell apoptosis and proliferation of gas...

journal_title：Digestive diseases and sciences

authors： Xu J,Zhang Z,Chen Q,Yang L,Yin J

更新日期：2020-02-01 00:00:00

abstract：:Under physiological conditions, the human gut adapts intestinal gas propulsion and evacuation to prevent intestinal gaseous complaints In this study we aimed to determine influences of the jejunum versus ileum on intestinal gas dynamics during a balanced meal. Paired studies were randomly performed with seven women an...

journal_title：Digestive diseases and sciences

authors： Harder H,Hernando-Harder AC,Franke A,Krammer HJ,Singer MV

更新日期：2006-05-01 00:00:00

abstract：:The results of 88 consecutive small-bowel enemas were compared retrospectively with the results of 52 routine small-bowel series and 50 barium enemas done in the same patients. Ninety-six percent of the diagnoses made by small-bowel enema were correct, as compared to only 65% made by routine small-bowel series. The in...

journal_title：Digestive diseases and sciences

authors： Gurian L,Jendrzejewski J,Katon R,Bilbao M,Cope R,Melnyk C

更新日期：1982-12-01 00:00:00

abstract：:Sirtuins (SIRT), first described as nicotinamide adenine dinucleotide (NAD+)-dependent type III histone deacetylases, are produced by cells to support in the defense against chronic stress conditions such as metabolic syndromes, neurodegeneration, and cancer. SIRT-3 is one of the most studied members of the mitochondr...

journal_title：Digestive diseases and sciences

authors： De Matteis S,Granato AM,Napolitano R,Molinari C,Valgiusti M,Santini D,Foschi FG,Ercolani G,Vespasiani Gentilucci U,Faloppi L,Scartozzi M,Frassineti GL,Casadei Gardini A

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:There is increased awareness about risks and benefits of using domperidone to treat gastroparesis. AIM:To describe the outcome of treating patients with refractory gastroparesis symptoms with domperidone. METHODS:Domperidone 10 mg QID or TID was prescribed to patients with refractory gastroparesis symptoms...

journal_title：Digestive diseases and sciences

authors： Schey R,Saadi M,Midani D,Roberts AC,Parupalli R,Parkman HP

更新日期：2016-12-01 00:00:00

abstract：:The aim of this study was to clarify the pathogenesis of Helicobacter pylori-negative duodenal ulcer (DU) by investigating the meal-stimulated serum gastrin (SG) response. The subjects were 9 patients with H. pylori-negative DU, 28 H. pylori-positive DU, 11 H. pylori-positive volunteers, and 30 H. pylori-negative volu...

journal_title：Digestive diseases and sciences

authors： Kamada T,Haruma K,Kusunoki H,Miyamoto M,Ito M,Kitadai Y,Yoshihara M,Chayama K,Tahara K,Kawamura Y

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:We hypothesized that the severity of dextran sodium sulfate (DSS)-induced colitis could differ between DSS preparations of the same molecular weight, and that this difference may be affected by the sulfur content. To test this, we used three DSS preparations of similar molecular weights but with different su...

journal_title：Digestive diseases and sciences

authors： Bamba S,Andoh A,Ban H,Imaeda H,Aomatsu T,Kobori A,Mochizuki Y,Shioya M,Nishimura T,Inatomi O,Sasaki M,Saitoh Y,Tsujikawa T,Araki Y,Fujiyama Y

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Transenteral (TE) administration of a bowel cleanser prior to colonoscopy avoids the discomfort associated with drinking a large volume of unpalatable cleanser. AIM:To explore patient comfort, preference for future colonoscopy, the efficacy and adverse events associated with TE bowel preparation. METHODS:B...

journal_title：Digestive diseases and sciences

authors： Jung SW,Jung DH,Shin YC,Moh IH,Yoo H,Jang SI,Shin SR,Kim JB,Park SH,Lee MS

更新日期：2015-01-01 00:00:00

abstract：:Free radical damage in reflux esophagitis of rats induced by 24-hr duodenojejunal ligation was studied. Oxygen free radicals were selectively blocked. Groups were: sham operation, reflux, reflux + superoxide dismutase (SOD), catalase, dimethylthiourea, allopurinol, and inactivated SOD or inactivated catalase alone or ...

journal_title：Digestive diseases and sciences

authors： Wetscher GJ,Hinder PR,Bagchi D,Perdikis G,Redmond EJ,Glaser K,Adrian TE,Hinder RA

更新日期：1995-06-01 00:00:00

abstract：:Using northern blot analysis and immunohistochemistry, we assessed the expression and distribution of human epidermal growth factor receptor-1 (HER-1), HER-2, and HER-3 in pancreatic tissues obtained from patients with acute pancreatitis (AP). Overall, HER-1, HER-2, and HER-3 mRNA levels were similar in the normal pan...

journal_title：Digestive diseases and sciences

authors： Ebert M,Friess H,Büchler MW,Korc M

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Biliary complications (BCs) occur in up to 40% of living donor liver transplant (LDLT) recipients. The aim of this study was to evaluate the efficacy of endoscopic therapy in the management of LDLT-related BCs. METHODS:A retrospective study of 100 LDLT recipients at a single transplant center over ...

journal_title：Digestive diseases and sciences

authors： Elwir S,Thompson J,Amateau SK,Trikudanathan G,Attam R,Hassan M,Kandaswamy R,Pruett T,Lake J,Chinnakotla S,Freeman ML,Arain MA

更新日期：2017-01-01 00:00:00

abstract：:Development of type 1 insulin-dependent diabetes mellitus has been recently reported in patients who underwent interferon-alpha (IFN-alpha) therapy because of chronic viral hepatitis. Furthermore IFN-alpha seems to be involved in the immunological events that lead to beta-cell destruction and development of type 1 dia...

journal_title：Digestive diseases and sciences

authors： di Cesare E,Previti M,Russo F,Brancatelli S,Ingemi MC,Scoglio R,Mazzù N,Cucinotta D,Raimondo G

更新日期：1996-08-01 00:00:00

abstract：:A comparative study of three different high-dose regimens of interferon-alpha-2b (IFN) was conducted in patients with chronic hepatitis C to determine which was better at obtaining a sustained remission. A total of 126 patients were assigned randomly to one of three groups: group A was given 10 million international u...

journal_title：Digestive diseases and sciences

authors： Iino S,Hino K,Kuroki T,Suzuki H,Yamamoto S

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND AND AIMS:The Gastroenterology Core Curriculum requires training in women's digestive disorders; however, requirements do not necessarily produce knowledge and competence. Our study goals were: (1) to compare perceptions of education, fellow-reported levels of competence, and attitudes towards training in wom...

journal_title：Digestive diseases and sciences

authors： Saha S,Roberson E,Richie K,Lindstrom MJ,Esposti SD,Wald A

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:The high mobility group protein A2 (HMGA2) is an architectural transcription factor that plays an important role in the development and progression of many malignant neoplasms. High expression of HMGA2 in gastric cancer correlates with invasiveness of cancer and is an independent prognostic factor. The reaso...

journal_title：Digestive diseases and sciences

authors： Zha L,Zhang J,Tang W,Zhang N,He M,Guo Y,Wang Z

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Minimal hepatic encephalopathy is the mildest form of the spectrum of hepatic encephalopathy (HE) that impairs health-related quality of life. We assessed (1) the usefulness of psychometric hepatic encephalopathy score and critical flicker frequency for the diagnosis of minimal hepatic encephalopath...

journal_title：Digestive diseases and sciences

authors： Dhiman RK,Kurmi R,Thumburu KK,Venkataramarao SH,Agarwal R,Duseja A,Chawla Y

更新日期：2010-08-01 00:00:00

abstract：:Gastroenterologists are in a unique position to assist women with chronic gastrointestinal disorders in order to optimize their health prior to pregnancy. Women, whether with chronic conditions or not, and their infants are more likely to be healthy when pregnancies are planned. Achieving a planned pregnancy at the id...

journal_title：Digestive diseases and sciences

authors： Sridhar A,Cwiak CA,Kaunitz AM,Allen RH

更新日期：2017-01-01 00:00:00

abstract：:We reviewed the discharge records of all diabetic ketoacidosis hospitalizations over 30 months for the presence of clinically significant upper gastrointestinal hemorrhage. Of 284 hospitalizations in 193 patients, hemorrhage occurred in 26 hospitalizations (9%) in 25 patients (13%). None required invasive therapy to a...

journal_title：Digestive diseases and sciences

authors： Faigel DO,Metz DC

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:The arrival of tacrolimus has drastically improved AALDLT recipients' survival. However, little data of tacrolimus have been reported concerning its effects on lipid metabolism for AALDLT recipients. AIM:Out aim was to investigate the relationship between tacrolimus blood concentration and lipid metabolism ...

journal_title：Digestive diseases and sciences

authors： Li HY,Li B,Wei YG,Yan LN,Wen TF,Zhao JC,Xu MQ,Wang WT,Ma YK,Yang JY

更新日期：2012-01-01 00:00:00

abstract：:We examined the role of capsaicin-sensitive afferent neurons in pH-dependent gastrin secretion in the rat stomach. The change in serum gastrin levels relative to changes in luminal pH (using omeprazole for luminal alkalization or 0.1 N HCl for luminal acidification) was studied after oral administration of 4% lidocain...

journal_title：Digestive diseases and sciences

authors： Nojima K,Sumii K,Sumii M,Okahara S,Haruma K,Yoshihara M,Kajiyama G

更新日期：2000-06-01 00:00:00

abstract：:There is growing recognition of the importance of assessing patient perceptions of treatment, especially patient satisfaction. The Gastroesophageal Reflux Disease (GERD) Treatment Satisfaction Questionnaire (GTSQ) was developed to assess satisfaction with GERD medication. A web-based survey, which included the GTSQ an...

journal_title：Digestive diseases and sciences

authors： Shikiar R,Flood E,Siddique R,Howell J,Dodd SL

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Previous studies have demonstrated the value of systematic feedback in enhancing endoscopic procedure performance. It remains unknown whether feedback may play a role in modifying physician performance in outpatient practice. This study aimed to assess the impact of systematic feedback on duration o...

journal_title：Digestive diseases and sciences

authors： Harewood GC

更新日期：2011-10-01 00:00:00

abstract：:The objective of this study was to test the feasibility of a screening strategy for IgG antibodies against Helicobacter pylori in patients presenting with upper abdominal complaints. Biopsy specimens were taken for histological and microbiological investigations from consecutive patients undergoing upper gastrointesti...

journal_title：Digestive diseases and sciences

authors： Werdmuller BF,V\/der Putten AB,Veenendaal RA,Lamers CB,Loffeld RJ

更新日期：1998-10-01 00:00:00

abstract：:Duodenal resistance to gastric outflow is known to participate in the regulation of gastric emptying of liquids in animals, but the role of this mechanism in humans has not been extensively investigated. In this work we studied the gastric emptying of liquids in patients with megaduodenum, who putatively have increase...

journal_title：Digestive diseases and sciences

authors： Troncon LE,Aprile LR,Oliveira RB,Iazigi N

更新日期：2000-11-01 00:00:00

abstract：:The study aimed to examine the serum serological response among H. pylori-infected patients with various upper gastrointestinal diagnoses; to ascertain whether it could be predictive to the diagnostic outcome of dyspepsia. One hundred seventy H. pylori-infected patients with dyspeptic symptoms but without previous tre...

journal_title：Digestive diseases and sciences

authors： Shiesh SC,Sheu BS,Yang HB,Tsao HJ,Lin XZ

更新日期：2000-04-01 00:00:00

abstract：:Insulinlike growth factor-1 (IGF-1) is an anabolic hormone synthesized by the liver upon stimulation by growth hormone (GH). IGF-1 exerts important effects on renal hemodynamics and renal sodium handling. The bioactivity of this hormone is influenced by its binding proteins (BP) of which IGF-BP3 favors retention in th...

journal_title：Digestive diseases and sciences

authors： Fernández-Rodriguez CM,Prada I,Andrade A,Moreiras M,Guitián R,Aller R,Lledó JL,Cacho G,Quiroga J,Prieto J

更新日期：2001-06-01 00:00:00