Risk factors for complications of percutaneous endoscopic gastrostomy.

Abstract:

BACKGROUND:Percutaneous endoscopic gastrostomy (PEG) is a commonly performed procedure for patients with severe dysphagia leading to malnutrition. Improved knowledge of risk factors for PEG-related complications might decrease patient discomfort and healthcare costs. AIM:The aim of the present study was to investigate factors associated with complications after PEG. METHODS:A retrospective review was performed for all patients referred for PEG placement from December 2002 to December 2012 in single-tertiary care center. PEG-related complications and risk factors were evaluated through chart reviews, endoscopic reports, and endoscopic and radiologic images. RESULTS:Among a total of 245 consecutive individuals (146 male, mean age 59.2 ± 12.6 years) enrolled, 43 major complications had developed. Multivariate analysis revealed that patients with an internal bolster of a PEG tube in the upper body of stomach were at significant risk for early [OR 6.127 (95 % CI 1.447-26.046)] and late complications [OR 6.710 (95 % CI 1.692-26.603)]. Abnormal leukocyte counts [OR 3.198 (95 % CI 1.174-8.716)], stroke as an indication for PEG [OR 3.047 (95 % CI 1.174-8.882)], and PEG tube placement by an inexperienced endoscopist [OR 3.401 (95 % CI 1.073-10.779)] were significantly associated with early complications. CONCLUSIONS:A PEG tube should not be inserted into the upper body of stomach to reduce complication risk, and PEG procedures should be performed by skilled endoscopists to prevent early complications. An abnormal leukocyte count can be a predictor of early complication, and care is needed when PEG is performed for patients with stroke.

journal_name

Dig Dis Sci

authors

Lee SP,Lee KN,Lee OY,Lee HL,Jun DW,Yoon BC,Choi HS,Kim SH

doi

10.1007/s10620-013-2891-7

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

117-25

issue

1

eissn

0163-2116

issn

1573-2568

journal_volume

59

pub_type

杂志文章
  • Interferon inhibits progression of liver fibrosis and reduces the risk of hepatocarcinogenesis in patients with chronic hepatitis C: a retrospective multicenter analysis of 652 patients.

    abstract::A retrospective multicenter analysis of 652 patients with chronic hepatitis C who have been treated with interferon (IFN) was performed to assess the effects of IFN on the clinical course and development of HCC. During a mean follow-up of 54.8 months, hepatocellular carcinoma (HCC) developed in 7.0% of the patients. T...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,多中心研究

    doi:10.1023/a:1013244326874

    authors: Takimoto M,Ohkoshi S,Ichida T,Takeda Y,Nomoto M,Asakura H,Naito A,Mori S,Hata K,Igarashi K,Hara H,Ohta H,Soga K,Watanabe T,Kamimura T

    更新日期:2002-01-01 00:00:00

  • Asymptomatic Helicobacter pylori gastritis is associated with increased sucrose permeability.

    abstract::Our aim was to investigate whether there are changes in permeability to sucrose in asymptomatic Helicobacter pylori gastritis. Nineteen asymptomatic subjects with Helicobacter pylori-associated gastritis with no or mild mucosal atrophy and 19 age- and sex-matched normal controls were studied by peroral load of sucrose...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1023/a:1018809913230

    authors: Borch K,Sjöstedt C,Hannestad U,Söderholm JD,Franzén L,Mårdh S

    更新日期:1998-04-01 00:00:00

  • Signet ring carcinoma of the pancreas, a rare variant with very high CEA values. Immunohistologic comparison with adenocarcinoma.

    abstract::Signet ring carcinoma of the pancreas is rare. We report a case which was remarkable for (1) diffuse, infiltrating growth which suggested chronic pancreatitis at laparotomy, and (2) an associated very high circulating carcinoembryonic antigen (CEA) level of 6400 ng/ml. The case report and autopsy are presented. Twelve...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01296277

    authors: Tracey KJ,O'Brien MJ,Williams LF,Klibaner M,George PK,Saravis CA,Zamcheck N

    更新日期:1984-06-01 00:00:00

  • Health-related quality of life in patients with Crohn's disease: influence of surgical operation--a prospective trial.

    abstract::Improvement of health-related quality of life (HRQOL) is a major determinant in decision-making for surgery in patients with Crohn's disease (CD). This study was designed to investigate the short- and long-term effect of surgical resection for CD on HRQOL. Sixteen patients were investigated within one week before surg...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1023/a:1026600428484

    authors: Tillinger W,Mittermaier C,Lochs H,Moser G

    更新日期:1999-05-01 00:00:00

  • Effects of stimulation and inhibition of acid secretion on gastric damage induced by platelet-activating factor.

    abstract::Intravenous administration of platelet-activating factor (PAF) induces extensive damage in rat gastric mucosa. The aim of the present study was to examine whether the presence or absence of acid in the gastric lumen could modify the PAF-induced gastric damage. The effects of inhibition of basal and pentagastrin-stimul...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01296615

    authors: Piqué JM,Pérez Ayuso RM,Bilbao J,Terés J

    更新日期:1991-12-01 00:00:00

  • Pseudotumorous chronic pancreatitis associated with inflammatory bowel disease.

    abstract::Chronic pancreatitis associated with inflammatory bowel disease is now considered as extraintestinal manifestation of that disease. The clinical and radiological features of the new entity are markedly different from those of chronic calcifying pancreatitis. We report the case of a 68-year-old man presenting with a ps...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1023/a:1010733308228

    authors: Grandval P,Barthet M,Desjeux A,Garcia S,Boustiere C,Poilroux B,Grimaud JC

    更新日期:2001-04-01 00:00:00

  • New enema treatments for inflammatory bowel disease.

    abstract::Two new preparations are under clinical trial for use in the treatment of ulcerative proctitis and left-sided colitis. One is 5-aminosalicylate, a component of sulfasalazine. This substance has virtually no immunomodulating capabilities. Evidence for efficacy equal to that of sulfasalazine in acute colitis has been ob...

    journal_title:Digestive diseases and sciences

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF01538136

    authors: Karp LC,Targan SR

    更新日期:1988-03-01 00:00:00

  • Diagnostic value of "bread-barium" swallow in patients with esophageal symptoms.

    abstract::The value of a "bread-barium" swallow for diagnosis of disordered esophageal motility was examined in 53 patients, 20 of whom complained of dysphagia, 20 retrosternal chest pain, and 13 heartburn; a further 19 subjects served as controls. Esophageal manometry in the patients with dysphagia and chest pain revealed majo...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01295808

    authors: Davies HA,Evans KT,Butler F,McKirdy H,Williams GT,Rhodes J

    更新日期:1983-12-01 00:00:00

  • Endoscopic Management of Biliary Leaks and Strictures After Living Donor Liver Transplantation: Optimizing Techniques for Successful Management.

    abstract:BACKGROUND AND AIMS:Biliary complications (BCs) occur in up to 40% of living donor liver transplant (LDLT) recipients. The aim of this study was to evaluate the efficacy of endoscopic therapy in the management of LDLT-related BCs. METHODS:A retrospective study of 100 LDLT recipients at a single transplant center over ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-016-4367-z

    authors: Elwir S,Thompson J,Amateau SK,Trikudanathan G,Attam R,Hassan M,Kandaswamy R,Pruett T,Lake J,Chinnakotla S,Freeman ML,Arain MA

    更新日期:2017-01-01 00:00:00

  • Interferon as treatment for acute hepatitis C. A meta-analysis.

    abstract::The efficacy of short-course (three months), low-dose (3 million units three times a week) interferon as treatment for acute hepatitis C was evaluated in a meta-analysis of controlled trials. Nine studies (five randomized and four nonrandomized) found by MEDLINE search were eligible for analysis. The outcomes assessed...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,meta分析

    doi:10.1007/BF02088245

    authors: Cammà C,Almasio P,Craxì A

    更新日期:1996-06-01 00:00:00

  • Acute liver failure due to lymphoma. A diagnostic concern when considering liver transplantation.

    abstract::Lymphomatous involvement of the liver may present as acute liver failure but is an absolute contraindication for liver transplantation. Therefore it is imperative to diagnose such patients since survival in this group is poor and recurrence is high. We describe two patients with acute liver failure referred for liver ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,评审

    doi:10.1007/BF02093804

    authors: Woolf GM,Petrovic LM,Rojter SE,Villamil FG,Makowka L,Podesta LG,Sher LS,Memsic L,Vierling JM

    更新日期:1994-06-01 00:00:00

  • Efficacy of new playback functions at reducing small-bowel wireless capsule endoscopy reading times.

    abstract:INTRODUCTION:Interpretation of video capsule data is time-consuming. Olympus capsule endoscopy (CE) software systems are equipped with auto-speed-adjusted and express-selected playback modes and overview function in an effort to reduce reading times. The clinical efficacy of these new playback features is unknown. Our ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-012-2074-y

    authors: Subramanian V,Mannath J,Telakis E,Ragunath K,Hawkey CJ

    更新日期:2012-06-01 00:00:00

  • The questionable efficacy of topical pharyngeal anesthesia in combination with propofol sedation in gastroscopy.

    abstract:BACKGROUND:Topical pharyngeal anesthesia as an adjunct to intravenous sedation to facilitate gastroscopy has been widely acknowledged; however, its efficacy has not been established when it is used in patients under deep sedation with propofol. AIMS:To demonstrate the limited value of topical pharyngeal anesthesia in ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s10620-012-2206-4

    authors: Tsai HI,Tsai YF,Liou SC,Su MY,Lin CC,Chang CJ,Yu HP

    更新日期:2012-10-01 00:00:00

  • Digital ambulatory manometry of the small intestine in healthy adults. Estimates of variation within and between individuals and statistical management of incomplete MMC periods.

    abstract::A new technique for ambulatory manometry of the small intestine with digital storage of signals is presented. Postprandial motility after a 1700-kJ meal and nighttime fasting motility were recorded in 19 healthy young adults. A comprehensive statistical approach was worked out to illuminate the statistical properties ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01537575

    authors: Husebye E,Skar V,Aalen OO,Osnes M

    更新日期:1990-09-01 00:00:00

  • Production of ectopic gastric intrinsic factor in gastric mucosa of humans with chronic gastritis.

    abstract:BACKGROUND:Ectopic expression of gastric intrinsic factor (IF) has been described in rodent models of chronic gastritis. AIMS:The current study undertook to determine if ectopic IF was also present in chronic gastritis in humans and might identify the process of ectopic protein expression as part of the response to ch...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-011-1738-3

    authors: Shao JS,Carmel R,Alpers DH

    更新日期:2011-11-01 00:00:00

  • Cost-effectiveness of chemoprevention with proton pump inhibitors in Barrett's esophagus.

    abstract:BACKGROUND:Proton pump inhibitors (PPIs) may reduce the risk of esophageal adenocarcinoma (EAC) in patients with Barrett's esophagus. PPIs are prescribed for virtually all patients with Barrett's esophagus, irrespective of the presence of reflux symptoms, and represent a de facto chemopreventive agent in this populatio...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-014-3186-3

    authors: Sharaiha RZ,Freedberg DE,Abrams JA,Wang YC

    更新日期:2014-06-01 00:00:00

  • Gut bacterial translocation contributes to microinflammation in experimental uremia.

    abstract:BACKGROUND:Microinflammation frequently develops in chronic uremia with pathological intestinal changes. However, the relationship between gut bacterial translocation and microinflammation in uremia has not been widely investigated. AIM:This study aimed to investigate whether gut microbiome dysbiosis and translocation...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-012-2242-0

    authors: Wang F,Zhang P,Jiang H,Cheng S

    更新日期:2012-11-01 00:00:00

  • Gastric bilirubin monitoring to assess duodenogastric reflux.

    abstract::Duodenogastric reflux (DGR) was assessed with 24-hour gastric bilirubin monitoring in 345 patients (219 men; 49 +/- 13 years) with foregut symptoms and 41 healthy subjects (24 men, 28 +/- 5 years). Bilirubin exposure was measured as percent time above absorbance level 0.25 and excessive DGR was defined above the 95th ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1023/a:1021069508731

    authors: Fein M,Freys SM,Sailer M,Maroske J,Tigges H,Fuchs KH

    更新日期:2002-12-01 00:00:00

  • Predicting short-term mortality and long-term survival for hospitalized US patients with alcoholic hepatitis.

    abstract:BACKGROUND:No study has evaluated current scoring systems for their accuracy in predicting short and long-term outcome of alcoholic hepatitis in a US population. METHODS:We reviewed electronic records for patients with alcoholic liver disease (ALD) admitted to Parkland Memorial Hospital between January 2002 and August...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-013-3020-3

    authors: Cuthbert JA,Arslanlar S,Yepuri J,Montrose M,Ahn CW,Shah JP

    更新日期:2014-07-01 00:00:00

  • Distribution and properties of neutral ceramidase activity in rat intestinal tract.

    abstract::Ceramide plays an important role in regulating cell proliferation and apoptosis. Recent studies indicate that generation of ceramide in the intestine from sphingomyelin hydrolysis may be implicated in colon cancer development. The enzymes that catalyze the further hydrolysis of ceramide in the intestine have, however,...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1023/a:1010792031910

    authors: Lundgren P,Nilsson A,Duan RD

    更新日期:2001-04-01 00:00:00

  • Effect of lactate and H+ on structure and function of rat intestine.

    abstract::Segments of rat ileum and colon were infused in vivo to test if 0.1 M lactate, 10(-4) M H+, or both altered mucosal structure and function. In the first series of experiments, lactate concentration was kept at 0.1 M while H+ was varied from 10(-4) to 10(-7) M. Lactate and 10(-4) M H+ in the colon, and lactate and 10(-...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01308119

    authors: Saunders DR,Sillery J

    更新日期:1982-01-01 00:00:00

  • Morphological aspects of necrosis as a guideline for treatment of necrotizing pancreatitis. A brief report about 50 patients.

    abstract::In a retrospective study, 50 patients with obvious necrotizing pancreatitis (NP) were allocated in four groups according to the morphological aspects of the necrosis. Appearance of ascite (N1), extrapancreatic spread of necrosis towards neighboring organs (N2), a large amount of necrosis (N3), and infected necrosis (N...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1023/a:1018890221620

    authors: Le Mée J,Janny S,Sauvanet A,Werner P,Belghiti J

    更新日期:1997-08-01 00:00:00

  • Production of a polar metabolite of 1,25-dihydroxyvitamin D3 in a rat liver perfusion system.

    abstract::When radiolabeled 1,25-dihydroxyvitamin D3 is added to the perfusion medium of a rat liver perfusion system, a polar metabolite of 1,25-dihydroxyvitamin D3 is formed in the liver and excreted in the bile. Addition of radiolabeled 1,25-dihydroxyvitamin D3 to the perfusion medium without a liver in the circuit results i...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01391637

    authors: Kumar R,Nagubandi S,Londowski JM

    更新日期:1981-03-01 00:00:00

  • Simultaneous endoluminal sonography and manometry to assess anal sphincter complex in normal subjects.

    abstract::The purpose of this study was to use simultaneous anal manometry and high-frequency endoluminal ultrasonography (EUS) to determine the relationship between resting anal pressure and cross-sectional area of the internal and external anal sphincters. Eleven normal subjects underwent simultaneous anal EUS and manometry u...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1023/a:1026605409557

    authors: Wong RF,Bonapace ES Jr,Chung CY,Liu JB,Parkman HP,Miller LS

    更新日期:1998-11-01 00:00:00

  • Is there a relation between irritable Bowel syndrome and urinary stone disease?

    abstract::Our aim was to investigate the role of renal colic, a clinical condition characterized by excruciating pain, in the etiopathogenesis of irritable bowel syndrome (IBS). Two groups of patients were enrolled in the study. Group I consisted of 59 patients (33 male and 26 female) with a median age of 41.9 (18 to 58) years....

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-005-2482-3

    authors: Erdem E,Akbay E,Sezgin O,Doruk E,Canpolat B,Cayan S

    更新日期:2005-03-01 00:00:00

  • Hepatitis A, hepatitis B, and combination hepatitis vaccines for immunoprophylaxis: an update.

    abstract::Since the publication of the last extensive review of hepatitis vaccines, use of inactivated hepatitis A vaccines has been extended to high-risk regions of the United States and specific patient groups, such as those with chronic liver disease, and use of the recombinant hepatitis B vaccines has been recommended for o...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,评审

    doi:10.1023/a:1015397807278

    authors: Koff RS

    更新日期:2002-06-01 00:00:00

  • Effect of tramadol and morphine on pain and gastrointestinal motor function in patients with chronic pancreatitis.

    abstract::Tramadol and morphine were compared for treatment of severe chronic pancreatitis pain and their interaction with gut motor function. Oral tramadol or morphine doses were titrated double-blinded and randomized for five days in 25 patients and pain, side effects, bowel function, orocecal and colonic transit, anal restin...

    journal_title:Digestive diseases and sciences

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1023/a:1026607703352

    authors: Wilder-Smith CH,Hill L,Osler W,O'Keefe S

    更新日期:1999-06-01 00:00:00

  • Effect of various prokinetic agents on post Roux-en-Y gastric emptying. Experimental and clinical observations.

    abstract::The effect of various prokinetic drugs was assessed in animals with Roux-en-Y gastrojejunostomy. The agents tested were (1) bethanechol 2.5 mg subcutaneously at 0 min and 30 min postprandially (pp); (2) metoclopramide 20 mg intravenous bolus at 0 min pp; (3) a combination of 1 and 2; (4) oxytocin 5 mg intramuscularly ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01536681

    authors: Hocking MP,Brunson ME,Vogel SB

    更新日期:1988-10-01 00:00:00

  • Biliary and pancreatic duct pressures measured by ERCP manometry in patients with suspected papillary stenosis.

    abstract::Papillary stenosis is an imprecisely defined clinical syndrome which eludes definitive diagnosis. In this study we evaluated 26 patients with suspected papillary stenosis by manometric examination of the sphincter of Oddi done during ERCP examination. Basal pressure in the sphincter of Oddi was elevated in 14 of the p...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01308431

    authors: Bar-Meir S,Geenen JE,Hogan WJ,Dodds WJ,Stewart ET,Arndorfer RC

    更新日期:1979-03-01 00:00:00

  • Overlap syndromes of autoimmune hepatitis: an open question.

    abstract::The headword "overlap syndromes" of liver diseases includes the coexistence of autoimmune hepatitis, primary biliary cirrhosis, and primary sclerosing cholangitis. These syndromes often represent a diagnostic and therapeutic challenge for hepatologists; it remains unclear whether these overlap syndromes form distinct ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,评审

    doi:10.1007/s10620-012-2378-y

    authors: Durazzo M,Premoli A,Paschetta E,Belci P,Spandre M,Bo S

    更新日期:2013-02-01 00:00:00