Mechanisms for contractile effect of Dai-kenchu-to in isolated guinea pig ileum.

abstract：:Forty-nine Japanese patients were enrolled in a randomized, placebo-controlled, double-blind trial of alpha-interferon for chronic non-A, non-B hepatitis: 24 patients received 3 million units of recombinant human alpha alpha-interferon (alpha-2a) thrice weekly for eight weeks, and 25 patients received placebo in a sim...

journal_title：Digestive diseases and sciences

authors： Omata M,Ito Y,Yokosuka O,Imazeki F,Tagawa M,Takano S,Hosoda K,Tada M,Ohto M,Ito K

更新日期：1991-09-01 00:00:00

abstract：:In this study, two antiallergic compounds, betamethasone and disodium cromoglycate were tested in an animal model of intestinal anaphylaxis. Rats, immunized with Nippostrongylus brasiliensis, were challenged intravenously with whole worm antigen or saline. Antigen challenge resulted in significant abnormalities: epith...

journal_title：Digestive diseases and sciences

authors： D'Incà R,Hunt RH,Perdue MH

更新日期：1992-11-01 00:00:00

abstract：:Orlistat (tetrahydrolipstatin) is a potent inhibitor of gastric and pancreatic lipase activity causing a diminution of free fatty acids in the intestinal lumen. The release of cholecystokinin (CCK) critically depends on the presence of free fatty acids in the small intestine. Postprandial CCK release and gallbladder c...

journal_title：Digestive diseases and sciences

authors： Froehlich F,Hartmann D,Guezelhan C,Gonvers JJ,Jansen JB,Fried M

更新日期：1996-12-01 00:00:00

abstract：:Biliary mucin was regarded as a major contributing factor in formation of pigment stones as well as cholesterol ones. The aim of this study was to elucidate the mechanism of biliary mucin secretion in canine gallbladder epithelial (CGBE) cells treated by lipopolysaccharides (LPS) with special reference to cyclooxygena...

journal_title：Digestive diseases and sciences

authors： Kim HJ,Lee SK,Kim MH,Seo DW,Min YI

更新日期：2003-04-01 00:00:00

abstract：:Duodenogastric reflux (DGR) was assessed with 24-hour gastric bilirubin monitoring in 345 patients (219 men; 49 +/- 13 years) with foregut symptoms and 41 healthy subjects (24 men, 28 +/- 5 years). Bilirubin exposure was measured as percent time above absorbance level 0.25 and excessive DGR was defined above the 95th ...

journal_title：Digestive diseases and sciences

authors： Fein M,Freys SM,Sailer M,Maroske J,Tigges H,Fuchs KH

更新日期：2002-12-01 00:00:00

abstract：:Although systemic steroids remain as the gold standard for the treatment of acute moderate to severe active ulcerative colitis (UC), 15-57% of patients do not achieve clinical remission. We sought to identify clinical, biological, or radiologic predictive factors of response to steroid treatment in acute UC attacks. T...

journal_title：Digestive diseases and sciences

authors： Bernal I,Mañosa M,Domènech E,Garcia-Planella E,Navarro M,Lorenzo-Zúñiga V,Cabré E,Gassull MA

更新日期：2006-08-01 00:00:00

abstract：:In addition to cholecystokinin, other hormones have been suggested to be involved in regulation of postprandial gallbladder contraction. We aimed to evaluate effects of growth hormone (GH) on gallbladder contractility and cholecystokinin release. Gallbladder and gastric emptying (by ultrasound) and cholecystokinin rel...

journal_title：Digestive diseases and sciences

authors： Moschetta A,Twickler TB,Rehfeld JF,van Ooteghem NA,Cabezas MC,Portincasa P,van Berge-Henegouwen GP,van Erpecum KJ

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Preclinical data demonstrate that activation of the renin-angiotensin system (RAS) contributes to mucosal inflammation, and RAS inhibition by angiotensin-converting-enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARB) improves colitis in animal models. Less is known regarding the effects of RAS i...

journal_title：Digestive diseases and sciences

authors： Jacobs JD,Wagner T,Gulotta G,Liao C,Li YC,Bissonnette M,Pekow J

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Corticosteroids and pentoxifylline reduce short-term mortality in severe alcoholic hepatitis (SAH), but not to the extent desired. Combining both drugs may lead to better survival, but has not yet been studied. AIM:To compare the efficacy of corticosteroids plus pentoxifylline with that of corticosteroids a...

journal_title：Digestive diseases and sciences

authors： Sidhu SS,Goyal O,Singla P,Gupta D,Sood A,Chhina RS,Soni RK

更新日期：2012-06-01 00:00:00

abstract：:If an effective hepatic assist system existed, it could serve as a bridge to transplantation. Most of the patients waiting for liver transplantation have chronic liver insufficiency but are not in hepatic coma. Various hepatic assist systems have been used to salvage patients with acute liver insufficiency. Most attem...

journal_title：Digestive diseases and sciences

authors： Takahashi T,Malchesky PS,Nosé Y

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Vitamin D deficiency is common in patients with inflammatory bowel diseases. The vitamin D receptor (VDR) is a nuclear hormone receptor mediating the activity of vitamin D hormone. Our previous studies showed that intestinal epithelial VDR signaling inhibits colitis by protecting the mucosal epithelial barri...

journal_title：Digestive diseases and sciences

authors： Golan MA,Liu W,Shi Y,Chen L,Wang J,Liu T,Li YC

更新日期：2015-07-01 00:00:00

abstract：:To examine the differentiating parameters between cholesterol and pigment gallstones, we compared the nucleation times, concentrations of biliary lipid and protein, and the distribution of vesicular cholesterol in gallbladder bile of 16 patients with cholesterol, eight patients with black pigment gallstones, and nine ...

journal_title：Digestive diseases and sciences

authors： Chijiiwa K,Hirota I,Noshiro H

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:DNA methylation mainly affects tumor suppressor genes in the development of hepatocellular carcinoma (HCC). However, sera methylation of specific genes in hepatitis B virus (HBV)-related HCC remains unknown. AIMS:The purpose of this study was to identify methylation frequencies of sera E-cadherin (CDH1), DN...

journal_title：Digestive diseases and sciences

authors： Dou CY,Fan YC,Cao CJ,Yang Y,Wang K

更新日期：2016-04-01 00:00:00

abstract：:In enriched canine parietal cell preparations, misoprostol, an analog of prostaglandin E1 methyl ester, was rapidly deesterified to misoprostol free acid. Under this circumstance, misoprostol and misoprostol free acid exhibited equal antisecretory potency against histamine-stimulated acid secretion and bound equally w...

journal_title：Digestive diseases and sciences

authors： Tsai BS,Kessler LK,Stolzenbach J,Schoenhard G,Bauer RF

更新日期：1991-05-01 00:00:00

abstract：:Salmonella species have recently been shown to involve the colon in a diffuse fashion resembling ulcerative colitis by radiographic and endoscopic appearance. We describe a case of Salmonella colitis in which the radiographic and colonoscopic features were focal ulcerations, mucosal edema, friability, and a loss of no...

journal_title：Digestive diseases and sciences

authors： Vender RJ,Marignani P

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Fatigue significantly impacts the quality of life of patients with inflammatory bowel disease (IBD). This study aimed to assess the effect of a personalized, intensive exercise program on fatigue, health-related quality of life (HRQoL), and cardiorespiratory fitness in patients with quiescent IBD an...

journal_title：Digestive diseases and sciences

authors： van Erp LW,Roosenboom B,Komdeur P,Dijkstra-Heida W,Wisse J,Horjus Talabur Horje CS,Liem CS,van Cingel REH,Wahab PJ,Groenen MJM

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Optical frequency domain imaging (OFDI) is a second-generation form of optical coherence tomography (OCT) providing comprehensive cross-sectional views of the distal esophagus at a resolution of ~7 μm. AIM:Using validated OCT criteria for squamous mucosa, gastric cardia mucosa, and Barrett's esophagus (BE),...

journal_title：Digestive diseases and sciences

authors： Sauk J,Coron E,Kava L,Suter M,Gora M,Gallagher K,Rosenberg M,Ananthakrishnan A,Nishioka N,Lauwers G,Woods K,Brugge W,Forcione D,Bouma BE,Tearney G

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND AND AIM:Atelectasis is one of the pulmonary complications associated with anesthesia. Little is known about atelectasis following endoscopic procedures under deep sedation. This study evaluated the frequency, risk factors, and clinical course of atelectasis after endoscopic resection. METHODS:A total of 349...

journal_title：Digestive diseases and sciences

authors： Choe JW,Jung SW,Song JK,Shim E,Choo JY,Kim SY,Hyun JJ,Koo JS,Yim HJ,Lee SW

更新日期：2016-01-01 00:00:00

abstract：:Gastric emptying of a solid meal and of 10 indigestible radiopaque solids was measured with scintigraphic and radiological techniques in 50 healthy volunteers (controls), 41 patients with insulin-dependent diabetes mellitus, and 50 patients with functional dyspepsia. Gastroparesis was found in 51% of our diabetic pati...

journal_title：Digestive diseases and sciences

authors： Caballero-Plasencia AM,Muros-Navarro MC,Martin-Ruiz JL,Valenzuela-Barranco M,de los Reyes-Garcia MC,Vilchez-Joya R,Casado-Caballero FJ,Gil-Extremera B

更新日期：1994-07-01 00:00:00

abstract：:To study the efficacy of standard blood tests of liver function (LFTs) and technetium-99m liver scan followed by laparoscopy in the diagnosis of solid malignant tumors of the liver, 100 consecutive patients were evaluated who had these tests because of clinical suspicion of liver neoplasm. Malignant liver tumors were ...

journal_title：Digestive diseases and sciences

authors： Lightdale CJ,Winawer SJ,Kurtz RC,Knapper WH

更新日期：1979-08-01 00:00:00

abstract：:Calcitonin gene-related peptide (CGRP) is thought to be involved in the regulation of gastric and mesenteric blood flow, in the control of gastric acid secretion and in the modulation of intestinal motility, yet the precise physiological roles of CGRP remain to be elucidated. To further examine the role(s) of CGRP in ...

journal_title：Digestive diseases and sciences

authors： Thompson BJ,Washington MK,Kurre U,Singh M,Rula EY,Emeson RB

更新日期：2008-01-01 00:00:00

abstract：:There is a growing body of experimental and clinical evidence to suggest that oral or rectal administration of 5-ASA or 5-ASA conjugates is associated with significant adverse side effects including pancreatitis, hepatitis, and renal toxicity. The objective of this study was to assess the ability of 5-ASA to interact ...

journal_title：Digestive diseases and sciences

authors： Grisham MB,Ware K,Marshall S,Yamada T,Sandhu IS

更新日期：1992-09-01 00:00:00

abstract：:Our purpose was to evaluate the relationship between the clinical and histological features in a cohort of patients who had gastroesophageal reflux-related lesions diagnosed after upper digestive endoscopy. In all, 589 patients scheduled for elective endoscopy in a multicentric prospective study were evaluated. Multip...

journal_title：Digestive diseases and sciences

authors： Aste H,Bonelli L,Ferraris R,Conio M,Lapertosa G

更新日期：1999-12-01 00:00:00

abstract：:Vagal control of pyloric resistance was evaluated in anesthetised pigs by recording gastropyloroduodenal motility and transpyloric flow during emptying of a liquid nonnutrient meal. Vagotomy did not modify pyloric resistance or the characteristics of the flow pulses. Electrical stimulation of the distal stumps of cerv...

journal_title：Digestive diseases and sciences

authors： Malbert CH,Mathis C,Laplace JP

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Patients with inflammatory bowel disease (IBD) are often immunosuppressed, and those patients receiving anti-tumor necrosis factor α (TNF) therapy can have lower antibody responses to vaccines. Pertussis cases are at their highest levels in the post-vaccine era. There is little data regarding responses to th...

journal_title：Digestive diseases and sciences

authors： Caldera F,Saha S,Wald A,Garmoe CA,McCrone S,Megna B,Ley D,Reichelderfer M,Hayney MS

更新日期：2018-06-01 00:00:00

abstract：:The present study aimed to investigate the role of nitric oxide on the oxidative damage in isolated rabbit gastric cells exposed to hypoxia-reoxygenation. Nitric oxide synthesis modulators such as L-arginine and NG-nitro-L-arginine methyl ester, a nitric oxide donor, sodium nitroprusside, and superoxide dismutase were...

journal_title：Digestive diseases and sciences

authors： Kim H,Kim KH

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:The impact of prior anti-TNF use on "real-life" outcomes of adalimumab therapy in ulcerative colitis (UC) is not well known. AIM:To compare the influence of prior anti-TNF use on the outcomes of adalimumab maintenance treatment in UC patients. We also assessed the effectiveness of adalimumab dose escalation...

journal_title：Digestive diseases and sciences

authors： Taxonera C,Iglesias E,Muñoz F,Calvo M,Barreiro-de Acosta M,Busquets D,Calvet X,Rodríguez A,Pajares R,Gisbert JP,López-Serrano P,Pérez-Calle JL,Ponferrada Á,De la Coba C,Bermejo F,Chaparro M,Olivares D,Alba C,Fernández

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Approximately 10% of children with celiac disease (CD) have ultra-short celiac disease (USCD), where histological abnormalities are limited to the duodenal bulb. The aim of our retrospective study was to identify clinical and serological characteristics at baseline and at follow-up of children with ...

journal_title：Digestive diseases and sciences

authors： Doyev R,Cohen S,Ben-Tov A,Weintraub Y,Amir A,Galai T,Moran-Lev H,Yerushalmy-Feler A

更新日期：2019-01-01 00:00:00

abstract：:Methionine (Meth) is an essential amino acid involved in DNA methylation and glutathione biosynthesis. We examined the effect of Meth on the development of steatohepatitis. Rats were fed (five weeks) amino acid-based Meth-choline-sufficient (A-MCS) or total deficient (MCD) diets and gavaged daily (two weeks) with vehi...

journal_title：Digestive diseases and sciences

authors： Oz HS,Chen TS,Neuman M

更新日期：2008-03-01 00:00:00

abstract：:Plasma lipids, apoprotein A-I and B in serum and in lipoprotein fractions (VLDL + LDL, HDL2, and HDL3) obtained by preparative ultracentrifugation, as well as postheparin lipoprotein lipase activity (H-TGL and LPL) were evaluated in 17 subjects with primary biliary cirrhosis (stage II and III) subdivided into two grou...

journal_title：Digestive diseases and sciences

authors： Baldo-Enzi G,Baiocchi MR,Grotto M,Floreani AR,Zagolin M,Chiaramonte M,Cera F,Fellin R

更新日期：1988-10-01 00:00:00