Protective effects of black cumin (Nigella sativa) oil on TNBS-induced experimental colitis in rats.

abstract：:The effects on the sphincter of Oddi of intravenous administration of dipyrone, 2.5 g; tramadol, 50 mg; indomethacin, 75 mg; N-butylscopolamine, 20 mg; and nitroglycerin, 1 mg, in comparison to physiological saline were assessed in a single-blind study in 36 patients hospitalized with upper abdominal pain. Basal sphin...

journal_title：Digestive diseases and sciences

authors： Brandstätter G,Schinzel S,Wurzer H

更新日期：1996-09-01 00:00:00

abstract：INTRODUCTION:The C-31G polymorphism in the survivin promoter could de-repress the cell-cycle-dependent transcription of the human survivin gene, resulting in overexpression of survivin. This survivin mutation has only been studied on cervical carcinoma. However, no study has ever been conducted to evaluate the effect o...

journal_title：Digestive diseases and sciences

authors： Yang L,Zhu H,Zhou B,Gu H,Yan H,Tang N,Dong H,Sun Q,Cong R,Chen G,Wang B

更新日期：2009-05-01 00:00:00

abstract：:Consumption of high-fiber diets has been recommended prior to fecal blood testing to increase bleeding from polyps, cancer, and other lesions associated with mucosal erosion in the gastrointestinal tract. The effect of a high-fiber diet on fecal hemoglobin loss was examined in 17 healthy subjects during two dietary pe...

journal_title：Digestive diseases and sciences

authors： Slavin JL,Melcher EA,Sundeen M,Schwartz S

更新日期：1991-07-01 00:00:00

abstract：:Response to interferon (IFN) therapy for chronic hepatitis C has been determined by the alteration of serum alanine aminotransferase (ALT) values. However, eradication of hepatitis C virus (HCV) could be another aim of the therapy. Thus, we serially measured serum HCV RNA levels during therapy and for at least 12 mont...

journal_title：Digestive diseases and sciences

authors： Aiyama T,Yoshioka K,Hirofuji H,Kusakabe A,Yamada M,Tanaka K,Kakumu S

更新日期：1994-10-01 00:00:00

abstract：:To investigate the colonic adenoma-adenocarcinoma progression sequence, DNA ploidy analysis was performed on hyperplastic polyps to adenocarcinomas. DNA ploidy data were then compared with immunocytochemical staining for proliferating cell nuclear antigen (PCNA). In hyperplastic polyps to villous adenomas, all cases w...

journal_title：Digestive diseases and sciences

authors： Tomita T

更新日期：1995-05-01 00:00:00

abstract：:Patients with previous gastric surgery for benign conditions are thought to be at increased risk for gastric cancer based on studies from Europe. Recommendations have been made to screen these patients repeatedly in order to detect early gastric cancers. We conducted a case-control study to estimate the risk in the Un...

journal_title：Digestive diseases and sciences

authors： Sandler RS,Johnson MD,Holland KL

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Endoscopic treatment is effective in the treatment of patients with bile duct injury after cholecystectomy. We aimed to investigate the long-term results of endoscopic treatment, factors predicting the recurrence of the stricture, and to determine the optimal endoscopic treatment. METHODS:The study...

journal_title：Digestive diseases and sciences

authors： Parlak E,Dişibeyaz S,Ödemiş B,Köksal AŞ,Küçükay F,Şaşmaz N,Şahin B

更新日期：2015-06-01 00:00:00

abstract：:We previously reported that various gastric irritants induced both apoptosis and necrosis in cultured gastric mucosal cells. In a continuation of this work, the present study has examined the effects of prostaglandin E2 (PGE2), a cytoprotective factor for gastric mucosa in vivo, on gastric irritant-induced apoptosis a...

journal_title：Digestive diseases and sciences

authors： Hoshino T,Takano T,Tsutsumi S,Tomisato W,Tsuchiya T,Mizushima T

更新日期：2002-10-01 00:00:00

abstract：:In the United States, more women than men seek health-care services for symptoms of irritable bowel syndrome (IBS). A number of explanations are given for this gender difference including the higher rates of somatic non-gastrointestinal symptoms and increased psychological distress reported by women with IBS. However,...

journal_title：Digestive diseases and sciences

authors： Cain KC,Jarrett ME,Burr RL,Rosen S,Hertig VL,Heitkemper MM

更新日期：2009-07-01 00:00:00

abstract：:Probiotic bacteria exhibit a variety of properties, which are unique to a particular strain. Lactobacillus acidophilus-SDC 2012, 2013 are new strains isolated from Korean infants' feces. The potential utility of Lactobacillus acidophilus-SDC 2012, 2013 in irritable bowel syndrome (IBS) was studied. Forty IBS patients ...

journal_title：Digestive diseases and sciences

authors： Sinn DH,Song JH,Kim HJ,Lee JH,Son HJ,Chang DK,Kim YH,Kim JJ,Rhee JC,Rhee PL

更新日期：2008-10-01 00:00:00

abstract：:Among the multifactorial causes of undernutrition in old age, gastrointestinal mucosa altered function and resulting specific malabsorption are the most relevant. Despite numerous studies that have dealt with the effects of aging on the digestive tract of mammals, results showed discrepancies in terms of proliferation...

journal_title：Digestive diseases and sciences

authors： Foligne B,Sénégas-Balas F,Antoine JM,Cayuela C,Rolf-Pedersen N,Balas D

更新日期：2004-08-01 00:00:00

abstract：:Radionuclide gastric solid-phase emptying was studied in 10 subjects with diabetic gastroparesis comparing the acute intravenous administration of cisapride (2.5, 5, 10 mg), placebo, and metoclopramide (10 mg). No hemodynamic or electrocardiographic changes were noted. While both cisapride and metoclopramide normalize...

journal_title：Digestive diseases and sciences

authors： McHugh S,Lico S,Diamant NE

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Sorafenib, a drug that inhibits Raf serine/threonine kinases mediating cell proliferation and receptor tyrosine kinases involved in angiogenesis, is approved for treatment of advanced hepatocellular carcinoma. AIMS:To explore the efficacy and safety of sorafenib for treating advanced HCC, and to identify cl...

journal_title：Digestive diseases and sciences

authors： Xie B,Wang DH,Spechler SJ

更新日期：2012-05-01 00:00:00

abstract：:Intravenous lidocaine was infused at 0.82 ml/min in a concentration of 1.2 mg/ml (2.3 mg/kg) for 120 min in awake chair-restrained baboons (Papio anubis), and measurements of esophageal peristalsis and LES pressure were compared before and after lidocaine or control infusions. Lidocaine produced a progressive and sign...

journal_title：Digestive diseases and sciences

authors： Sinar DR,Carey LC,Cordova C,Fletcher JR,Castell DO

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:Determining the risk stratification of nonvariceal upper gastrointestinal bleeding (NVUGIB) plays a vital role in treating upper gastrointestinal bleeding (UGIB). Traditional scores like Glasgow-Blatchford score (GBS), Rockall score (RS), and AIMS65 score have been widely utilized in UGIB practice, however e...

journal_title：Digestive diseases and sciences

authors： Yue W,Liu Y,Jiang W,Huang J,Liu J

更新日期：2020-06-24 00:00:00

abstract：:Many studies have indicated changes in neuropeptides in inflammatory bowel disease (IBD), but with contradictory results. Nerve growth factor also has a potential role in the maintenance of enteric nerves and may be associated with IBD. A quantitative immunohistochemical method was used to measure area density of immu...

journal_title：Digestive diseases and sciences

authors： Lee CM,Kumar RK,Lubowski DZ,Burcher E

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND/AIMS:Studies have shown that celiac disease can affect individuals in all age groups. However, few studies have described the disease in the elderly. The goal of this study is to characterize celiac disease in the elderly by comparing to a population of young adults with celiac disease. METHODS:Review of a ...

journal_title：Digestive diseases and sciences

authors： Mukherjee R,Egbuna I,Brar P,Hernandez L,McMahon DJ,Shane EJ,Bhagat G,Green PH

更新日期：2010-11-01 00:00:00

abstract：:Apoptosis is an important process in a wide variety of different biological systems. In addition to caspases, recently, calpains, another family of proteases, have been found to be involved in apoptosis of many cell systems. This study is designed with the aims to evaluate the possible effect of Z-LLY-FMK (a calpain i...

journal_title：Digestive diseases and sciences

authors： Sheen-Chen SM,Ho HT,Eng HL

更新日期：2009-11-01 00:00:00

abstract：:The bile acids in brown pigment stones and gallbladder bile were fractionated into free acids, glycine and taurine conjugates, and sulfates using diethylaminohydroxypropyl Sephadex LH-20 (DEAP-LH-20) column chromatography and were quantitated by gas chromatography. Twenty-eight cases of brown pigment stones were studi...

journal_title：Digestive diseases and sciences

authors： Akiyoshi T,Nakayama F

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Capsule endoscopy (CE) has the problem that lumen visualization is impaired by bubbles, bile, and debris. The benefits of bowel preparation are still controversial and the best method remains to be determined. The objective of this study was to evaluate the effect of the method of bowel preparation ...

journal_title：Digestive diseases and sciences

authors： Park SC,Keum B,Seo YS,Kim YS,Jeen YT,Chun HJ,Um SH,Kim CD,Ryu HS

更新日期：2011-06-01 00:00:00

abstract：:Data on performance characteristics of flexible sigmoidoscopy (FS) between age groups are limited. This study evaluates screening FS in subjects > or = 75 years of age (elderly) compared with ages 50-74 years (general screening population). Data were collected on patient characteristics, insertion depth, procedural di...

journal_title：Digestive diseases and sciences

authors： Pabby A,Suneja A,Heeren T,Farraye FA

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Heat shock protein 70-2 (HSP70-2) has a cytoprotective role in various conditions and also protects the gastric mucosa. Recently, polymorphism of HSP70-2 at position 1267 was suggested to be associated with carcinogenesis. We investigated the association of this polymorphism with the risk of gastric cancer i...

journal_title：Digestive diseases and sciences

authors： Shibata T,Arisawa T,Tahara T,Yoshioka D,Maruyama N,Fujita H,Kamiya Y,Nakamura M,Nagasaka M,Iwata M,Takahama K,Watanabe M,Hirata I,Nakano H

更新日期：2009-01-01 00:00:00

abstract：:Depletion of granulocytes and monocytes (GM) by selective apheresis (GMA) with an Adacolumn exerts an anti-inflammatory effect in patients with ulcerative colitis (UC) or rheumatoid arthritis. However, the mechanism of the anti-inflammatory effect of GMA is not fully understood yet. We investigated the effect of GMA o...

journal_title：Digestive diseases and sciences

authors： Sakimura K,Omori T,Iwashita E,Yoshida T,Tsuzuki Y,Fujimori K,Konishi F,Yoshida Y,Anzai H,Suzuki H,Sugawara S,Takeda Y,Hiraishi K,Saniabadi AR,Ide T,Miura S,Ota S

更新日期：2006-09-01 00:00:00

abstract：:NSAID use and Helicobacter pylori both cause damage to the gastric mucosa and can cause peptic ulcers. Our aim was to test the relationship between gastric mucosal polymorphonuclear leukocyte (PMN) infiltration and the severity of NSAID-induced gastric injury. H. pylori density, mucosal interleukin-8 (IL-8), and nitri...

journal_title：Digestive diseases and sciences

authors： Shiotani A,Yamaoka Y,El-Zimaity HM,Saeed MA,Qureshi WA,Graham DY

更新日期：2002-01-01 00:00:00

abstract：:Previous studies showed that bile salts had a promoting effect on colon cancer development and this effect was inhibited by ursodeoxycholate (UDC). We recently found that both human colorectal adenomas and carcinomas were associated with a specific decrease in alkaline sphingomyelinase activity. In this work, we compa...

journal_title：Digestive diseases and sciences

authors： Duan RD,Cheng Y,Tauschel HD,Nilsson A

更新日期：1998-01-01 00:00:00

abstract：:Idiopathic chronic constipation has been correlated to neural abnormalities that consist of a reduced number of myenteric plexus neurons and a decreased concentration of VIP-positive nerve fibers within the circular muscle. Recent studies hypothesized the involvement of nitric oxide in motility disorders of the human ...

journal_title：Digestive diseases and sciences

authors： Cortesini C,Cianchi F,Infantino A,Lise M

更新日期：1995-11-01 00:00:00

abstract：:A 70-year-old woman with secretory diarrhea was studied with a novel technique of recording small intestinal myoelectrical activity which allowed us to obtain long, uninterrupted records of slow waves and spikes at eight or more different intestinal levels simultaneously. Typical migrating action potential complexes (...

journal_title：Digestive diseases and sciences

authors： Coremans G,Janssens J,Vantrappen G,Chaussade S,Ceccatelli P

更新日期：1987-10-01 00:00:00

abstract：:The morphine-Prostigmin test (MPT) has been advocated as a diagnostic test for identifying patients with papillary stenosis. We studied 14 patients referred for possible papillary stenosis with the MPT and ERCP sphincter of Oddi manometry. The response to the MPT (symptoms, serum amylase/lipase values) was evaluated b...

journal_title：Digestive diseases and sciences

authors： LoGiudice JA,Geenen JE,Hogan WJ,Dodds WJ

更新日期：1979-06-01 00:00:00

abstract：BACKGROUND:HIV progression is characterized by immune activation and microbial translocation from the gut. Short-chain fatty acids (SCFAs) are essential for gut homeostasis. Decreased intestinal SCFAs play a role in rapid HIV progression. AIMS:To compare the SCFA profile, intestinal microbiome, and intestinal mucosal ...

journal_title：Digestive diseases and sciences

authors： Qing Y,Xie H,Su C,Wang Y,Yu Q,Pang Q,Cui F

更新日期：2019-07-01 00:00:00

abstract：:Experimental graft-versus-host disease (GVHD) causes immune-mediated intestinal injury. The adhesion molecule lymphocyte function associated antigen-1 (LFA-1) is involved in leukocyte homing to areas of inflammatory injury. Our hypothesis was that LFA-1 is increased in the GVHD injured small bowel and colon. We found ...

journal_title：Digestive diseases and sciences

authors： Poritz LS,Olt GJ,Ruggiero FM,Colony P,Tilberg AF,Koltun WA

更新日期：1998-02-01 00:00:00