Gut Microbiome, Short-Chain Fatty Acids, and Mucosa Injury in Young Adults with Human Immunodeficiency Virus Infection.

abstract：BACKGROUND:The pentapeptide ghrelin agonist, relamorelin, accelerates colonic transit in patients with chronic constipation (CC). In a murine model, relamorelin decreased excitability of colonic circular smooth muscle cells and colonic intraluminal pressure. AIM:To determine short-term effects of relamorelin on coloni...

journal_title：Digestive diseases and sciences

authors： Acosta A,Camilleri M,Busciglio I,Boldingh A,Nelson AD,Burton D

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND AND AIM:Previous studies evaluating the safety of endoscopic retrograde cholangiopancreatography (ERCP) in patients with end-stage renal disease (ESRD) undergoing hemodialysis reported an increased risk of post-procedural bleeding. We investigated the safety and efficacy of ERCP for the treatment of choledoc...

journal_title：Digestive diseases and sciences

authors： Kim SB,Kim KH,Kim TN

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND AND AIMS:The impact of obesity on survival following liver transplantation is unclear, and existing studies report conflicting results. Our current study aims to further delineate the impact of obesity using population-based registry data from the USA. METHODS:All US adult liver transplant recipients from 2...

journal_title：Digestive diseases and sciences

authors： Wong RJ,Cheung R,Perumpail RB,Holt EW,Ahmed A

更新日期：2015-04-01 00:00:00

abstract：:The aim of this study was to assess the potential of leflunomide, an immunosuppressant in rheumatoid arthritis, as a second-line immunosuppression treatment of patients with Crohn's disease refractory or intolerant to azathioprine. The study cohort consisted of 24 patients. The primary end point was steroid-free remis...

journal_title：Digestive diseases and sciences

authors： Holtmann MH,Gerts AL,Weinman A,Galle PR,Neurath MF

更新日期：2008-04-01 00:00:00

abstract：:Musashi-1 (Msi-1), a mammalian neural RNA-binding protein, has been found to play important roles in the maintenance of stem cell states and differentiation in neural stem cells and mouse intestinal cells. We explored Msi-1 expression and its potential implications in the human stomach. Reverse transcription-PCR revea...

journal_title：Digestive diseases and sciences

authors： Murata H,Tsuji S,Tsujii M,Nakamura T,Fu HY,Eguchi H,Asahi K,Okano H,Kawano S,Hayashi N

更新日期：2008-02-01 00:00:00

abstract：:Clinical observations reveal that alcohol intake is associated with an increase in upper gastrointestinal hemorrhage requiring hospitalization and that nitroglycerin or long-acting nitrates lower this risk. Nitroglycerin, a gastric vasodilator that can increase gastric fluid volume, protects the rodent stomach against...

journal_title：Digestive diseases and sciences

authors： Leung FW,Chan CC

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND AND AIMS:The present study aimed to identify the differential expressed genes that are related to acute pancreatitis. METHODS:Microarray datasets GSE109227 and GSE3644 were downloaded from the public database and analyzed to screen the genes. Afterward, integrated analysis of these genes were performed, inc...

journal_title：Digestive diseases and sciences

authors： Fan L,Hui X,Mao Y,Zhou J

更新日期：2020-06-01 00:00:00

abstract：:Colonic diverticula have been generally accepted as a source of massive hemorrhaging. Little is known, however, about fecal occult blood loss from colonic diverticula and diverticulosis. We retrospectively investigated the possibility of minor bleeding in 737 diverticula cases diagnosed from April 1989 to May 1994. Th...

journal_title：Digestive diseases and sciences

authors： Ohyama T,Sakurai Y,Ito M,Sezai S,Kamisaka K,Abe T,Ikegami F,Kobayashi Y

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:SEL1L gene product is implicated in the endoplasmic reticulum (ER)-associated protein degradation and Unfolded Protein Response pathways. This gene and associated miRNAs have been indicated as predictive and prognostic markers of pancreatic cancer. AIM:Explore the role of SEL1L in colorectal cancer (CRC) pr...

journal_title：Digestive diseases and sciences

authors： Ashktorab H,Green W,Finzi G,Sessa F,Nouraie M,Lee EL,Morgano A,Moschetta A,Cattaneo M,Mariani-Costantini R,Brim H,Biunno I

更新日期：2012-04-01 00:00:00

abstract：:The purpose of the present study is to show anomalies of the plasma cAMP response of patients with hepatic disorders to a single injection of a low dose of glucagon (1 microgram/kg body wt). The response was markedly blunted in patients with liver cirrhosis and potentiated in patients with acute or chronic hepatitis. ...

journal_title：Digestive diseases and sciences

authors： Maekubo H,Matsushima T,Okada F,Honma M,Ui M

更新日期：1980-09-01 00:00:00

abstract：:After gastrectomy, Roux-Y limb reconstruction leads to duodenojejunal motor disturbances. Because motilin and pancreatic polypeptide (PP) play a role in the regulation of digestive motility, their plasma concentrations were determined in rats after Roux-Y gastrectomy. Three months after a distal Roux-Y gastrectomy, co...

journal_title：Digestive diseases and sciences

authors： Le Blanc-Louvry I,Ducrotte P,Chayvialle JA,Coquerel A,Michot F,Ténière P

更新日期：2000-08-01 00:00:00

abstract：:Gastroesophageal reflux disease (GERD) is present in up to 75% of patients with chronic refractory ear, nose, and throat (ENT) symptoms, and proton pump inhibitor (PPI) therapy induces symptom relief in the majority of these patients. It has been suggested that endoscopic findings and quantification of esophageal acid...

journal_title：Digestive diseases and sciences

authors： Poelmans J,Feenstra L,Tack J

更新日期：2006-02-01 00:00:00

abstract：:Data about colonic mucosa transport of short-chain fatty acids in cirrhotic patients are still lacking. The aim of the present study was to compare the rectal mucosa transport of n-butyrate and its effect on transport of other electrolytes and endoluminal pH in normal subjects and in cirrhotic patients by using a rect...

journal_title：Digestive diseases and sciences

authors： Onori L,Pimpo MT,Palumbo GC,Gili L,Marchetti G,Saltarelli P,Aggio A,Frieri G

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Diabetic gastroparesis is a common complication of diabetes mellitus, which mainly affects women. Previous studies have demonstrated that oxidative stress is involved in its onset and development. AIMS:This study evaluated the role of vitamin C on diabetes-associated gastric dysmotility. METHODS:Female rat...

journal_title：Digestive diseases and sciences

authors： Da Silva LM,da Silva RCMVAF,Maria-Ferreira D,Beltrame OC,da Silva-Santos JE,Werner MFP

更新日期：2017-09-01 00:00:00

abstract：:The potential effect of recombinant human interleukin-11 (rhIL-11) on trinitrobenzene sulfonic acid (TNB)-induced colitis was investigated in rats. Intrarectal TNB (40 mg in 0.25 ml 40% ethanol) produced significant ulcerative colitis. The lesions were most severe at three days after TNB instillation, and then decline...

journal_title：Digestive diseases and sciences

authors： Qiu BS,Pfeiffer CJ,Keith JC Jr

更新日期：1996-08-01 00:00:00

abstract：PURPOSE:In previous studies the NFKBIA 3'UTR (untranslated region) AA genotype was associated with Crohn's disease (CD), while the NFKB1-94ins/delATTG mutation increased the risk for ulcerative colitis (UC). The aim of our study was to investigate these two polymorphisms and patients' response to medical therapy and/or...

journal_title：Digestive diseases and sciences

authors： Szamosi T,Lakatos PL,Hungarian IBD Study Group.,Szilvasi A,Lakatos L,Kovacs A,Molnar T,Altorjay I,Papp M,Szabo O,Satori A,Tulassay Z,Miheller P,Horvath HC,Papp J,Tordai A,Andrikovics H

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND AND AIM:Vascularity is a critical feature in the evaluation of pancreatic neuroendocrine tumor (PNET). When done by EUS, contrast agents are recommended. However, vascular architecture (VA) can also be evaluated by routine Doppler flow in EUS without contrast agents. Our aim was to provide a simple VA classi...

journal_title：Digestive diseases and sciences

authors： Chen K,Zhang W,Zhang Z,He Y,Liu Y,Yang X

更新日期：2018-11-01 00:00:00

abstract：:Papillary stenosis is an imprecisely defined clinical syndrome which eludes definitive diagnosis. In this study we evaluated 26 patients with suspected papillary stenosis by manometric examination of the sphincter of Oddi done during ERCP examination. Basal pressure in the sphincter of Oddi was elevated in 14 of the p...

journal_title：Digestive diseases and sciences

authors： Bar-Meir S,Geenen JE,Hogan WJ,Dodds WJ,Stewart ET,Arndorfer RC

更新日期：1979-03-01 00:00:00

abstract：BACKGROUND:Partially covered metal stents (PCMS) have been increasingly used for both malignant and benign biliary indications. This study reports their complications and subsequent management. METHODS:Over 5 years, all patients receiving biliary PCMS were followed prospectively until stent-related dysfunction or deat...

journal_title：Digestive diseases and sciences

authors： Ho H,Mahajan A,Gosain S,Jain A,Brock A,Rehan ME,Ellen K,Shami VM,Kahaleh M

更新日期：2010-02-01 00:00:00

abstract：:During topical dissolution of gallstones, solvent can escape to the duodenum causing toxic effects that have not yet been adequately quantified. We compared the local intestinal cytotoxic and systemic hepatotoxic effects of two gallstone solvents, methyl tert-butyl ether and ethyl propionate, on the rabbit's duodenum....

journal_title：Digestive diseases and sciences

authors： Clerici C,Gentili G,Zakko SF,Balò S,Miglietti M,Giansanti M,Modesto R,Guttermuth CF,Morelli A

更新日期：1997-03-01 00:00:00

abstract：:Cholestasis, which affects phospholipid trafficking, therefore would be expected to alter canalicular membrane phospholipid composition and fluidity, as well as fatty acid composition of membrane phospholipid. These alterations may affect transcytotic vesicle fusion and would be expected to cause variety of cholestati...

journal_title：Digestive diseases and sciences

authors： Hyogo H,Tazuma S,Kajiyama G

更新日期：1999-08-01 00:00:00

abstract：:Nonalcoholic steatohepatitis is the fastest-growing indication for the liver transplant and a leading cause of hepatocellular carcinoma among patients listed for liver transplantation in the USA. Post-transplant nonalcoholic hepatic steatosis and steatohepatitis are frequent complications of liver transplantation. Non...

journal_title：Digestive diseases and sciences

authors： Samji NS,Verma R,Keri KC,Singal AK,Ahmed A,Rinella M,Bernstein D,Abdelmalek MF,Satapathy SK

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Human hepatocellular carcinoma (HCC) is one of the most common fatal cancers and an important health problem worldwide, but its mechanism is still unclear. Microtubule (MT) kinesin motor proteins orchestrate a variety of cellular processes (e.g. mitosis, motility and organelle transportation) and have been i...

journal_title：Digestive diseases and sciences

authors： Huang X,Liu F,Zhu C,Cai J,Wang H,Wang X,He S,Liu C,Yao L,Ding Z,Zhang Y,Zhang T

更新日期：2014-04-01 00:00:00

abstract：:There are no requirements concerning the amplitude of simultaneous contractions among the present criteria for the manometric diagnosis of diffuse esophageal spasm. The purpose of this investigation was to determine whether the current criteria effectively identify an appropriately homogenous patient population. Sixty...

journal_title：Digestive diseases and sciences

authors： Allen ML,DiMarino AJ Jr

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Patients with diarrhea-predominant irritable bowel syndrome (IBS-D) appear to have increased intestinal permeability; it has been suggested that activation of protease-activated receptor-2 (PAR-2) receptors is responsible for this alteration. The aims of this study are to evaluate (1) if rectal (lar...

journal_title：Digestive diseases and sciences

authors： Lee JW,Park JH,Park DI,Park JH,Kim HJ,Cho YK,Sohn CI,Jeon WK,Kim BI

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Recent data suggest the involvement of both the adaptive and the innate immune system in celiac disease (CD). However, little is known about the immune phenotype of children with CD and its alteration upon dietary intervention. AIMS:We characterized the prevalence of major interacting members of the adaptiv...

journal_title：Digestive diseases and sciences

authors： Cseh Á,Vásárhelyi B,Szalay B,Molnár K,Nagy-Szakál D,Treszl A,Vannay Á,Arató A,Tulassay T,Veres G

更新日期：2011-03-01 00:00:00

abstract：:Over a one-year period, 95 children and adolescents presenting with epigastric pain and/or vomiting, and without associated risk factors for development of peptide disease, underwent endoscopic antral biopsies for pathologic diagnosis and to detect presence of Campylobacter ss. pylori (C. pylori). Additional biopsies ...

journal_title：Digestive diseases and sciences

authors： Glassman MS,Schwarz SM,Medow MS,Beneck D,Halata M,Berezin S,Newman LJ

更新日期：1989-10-01 00:00:00

abstract：:The specificity of polymerase chain reaction monoclonality in the diagnosis of gastric lymphoma was prospectively evaluated. Gastric mucosal tissue from normal gastric mucosa (N = 13), benign gastric ulcers (N = 3), chronic Helicobacter pylori gastritis (N = 3), gastric mucosa-associated lymphoid tissue (N = 16), and ...

journal_title：Digestive diseases and sciences

authors： Weston AP,Banerjee SK,Horvat RT,Cherian R,Campbell DR,Zoubine MN

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND AND AIM:Aberrant methylation of specific genes is frequent event in hepatocellular carcinoma (HCC). Our present study aims to explore the methylation levels of acid phosphatase locus 1 (ACP1), bone morphogenetic protein 4 (BMP4), and testis-specific protein, Y-encoded-like 5 (TSPYL5) and their potential clin...

journal_title：Digestive diseases and sciences

authors： Qiu X,Hu B,Huang Y,Deng Y,Wang X,Zheng F

更新日期：2016-01-01 00:00:00

abstract：:Duodenogastric reflux (DGR) was assessed with 24-hour gastric bilirubin monitoring in 345 patients (219 men; 49 +/- 13 years) with foregut symptoms and 41 healthy subjects (24 men, 28 +/- 5 years). Bilirubin exposure was measured as percent time above absorbance level 0.25 and excessive DGR was defined above the 95th ...

journal_title：Digestive diseases and sciences

authors： Fein M,Freys SM,Sailer M,Maroske J,Tigges H,Fuchs KH

更新日期：2002-12-01 00:00:00