Effects of prostaglandin E2 on gastric irritant-induced apoptosis.

abstract：:Modern methods of diagnosing diarrhea-predominant irritable bowel syndrome (D-IBS) require a "diagnosis of exclusion" approach. In this study we aim to test the diagnostic ability of using the fluctuation of frequency and consistency of bowel patterns in IBS to discriminate it from other causes of diarrhea. Eligible s...

journal_title：Digestive diseases and sciences

authors： Pimentel M,Hwang L,Melmed GY,Low K,Vasiliauskas E,Ippoliti A,Yang J,Lezcano S,Conklin JL,Sahakian A

更新日期：2010-01-01 00:00:00

abstract：:Our aim was to compare standard liver function tests (serum bilirubin, serum albumin and prothrombin concentration), with lidocaine and monoethylglycinexylidide pharmacokinetic parameters, after oral lidocaine administration, to assess hepatic function of cirrhotic individuals. Twenty-one consecutive cirrhotic patient...

journal_title：Digestive diseases and sciences

authors： Muñoz AE,Miguez C,Rubio M,Bartellini M,Levi D,Podestá A,Niselman V,Terg R

更新日期：1999-04-01 00:00:00

abstract：:Gastritis, an inflammatory state in gastric mucosa, can be induced experimentally in various ways. The present study considered the iodoacetamide model (Iodo). Omega-3 fatty acids (fish oil), black seed oil, and curcuminoids (natural products) in addition to omeprazole (synthetic proton-pump inhibitor) were tested. Su...

journal_title：Digestive diseases and sciences

authors： Elseweidy MM,Younis NN,Amin RS,Abdallah FR,Fathy AM,Yousif ZA

更新日期：2008-07-01 00:00:00

abstract：:The aim of the present study was to evaluate the influence of the exogenous nitric oxide donor glyceryl trinitrate on cerulein-induced gallbladder contraction in patients with acalculous biliary pain. Quantitative hepatobiliary scintigraphy was performed on 33 patients. From the 60th min cerulein (1 ng/kg body wt/min ...

journal_title：Digestive diseases and sciences

authors： Madácsy L,Velosy B,Szepes A,Szilvássy Z,Pávics L,Csernay L,Lonovics J

更新日期：2002-09-01 00:00:00

abstract：PURPOSE:The purpose of this study was to assess safety, efficacy, and clinical outcomes following transcatheter arterial embolization (TAE) of acute gastrointestinal (GI) bleeding. MATERIALS AND METHODS:Ninety-five patients (male:female ratio = 53:42, mean age 62 years) that underwent 95 TAEs for GI hemorrhage between...

journal_title：Digestive diseases and sciences

authors： Yap FY,Omene BO,Patel MN,Yohannan T,Minocha J,Knuttinen MG,Owens CA,Bui JT,Gaba RC

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Wnt ligand binding initiates the interaction between Frizzled and Dvl proteins. However, the regulation of Frizzled-Dvl proteins interaction remains largely unknown. AIMS:The present study aims to elucidate the regulation of Frizzled-Dvl interaction by WDR34. METHODS:The protein levels of WDR34 in hepatoce...

journal_title：Digestive diseases and sciences

authors： Luo X,Liu Y,Ma S,Liu L,Xie R,Wang S

更新日期：2019-09-01 00:00:00

abstract：:The 1993 Milwaukee Cryptosporidium outbreak posed several questions regarding appropriate management and prognosis of inflammatory bowel disease patients acutely infected with this organism. We prospectively identified and monitored 12 patients with stable ulcerative colitis or Crohn's disease who suffered abrupt clin...

journal_title：Digestive diseases and sciences

authors： Manthey MW,Ross AB,Soergel KH

更新日期：1997-08-01 00:00:00

abstract：:Cirrhotic patients with hepatocellular carcinoma (HCC) frequently develop hepatic encephalopathy. Metabolic etiology of encephalopathy is less often considered in these patients. Although paraneoplastic hypercalcemia may be associated with several malignant tumors, it has also been described in HCC [1-4], and may caus...

journal_title：Digestive diseases and sciences

authors： Tudela P,Soldevila B,Mòdol JM,Domènech E

更新日期：2007-11-01 00:00:00

abstract：:Clinical observations reveal that alcohol intake is associated with an increase in upper gastrointestinal hemorrhage requiring hospitalization and that nitroglycerin or long-acting nitrates lower this risk. Nitroglycerin, a gastric vasodilator that can increase gastric fluid volume, protects the rodent stomach against...

journal_title：Digestive diseases and sciences

authors： Leung FW,Chan CC

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) recurrence after liver transplantation (LT) is universal and tends to be more aggressive. Data on post-transplant HCV genotype 4 treatment is scarce. The aim of this study is to assess the safety and efficacy of pegylated interferon alpha-2a (PEG-IFN) in combination with ribavirin in ...

journal_title：Digestive diseases and sciences

authors： Al-Hamoudi W,Mohamed H,Abaalkhail F,Kamel Y,Al-Masri N,Allam N,Alqahtani S,Al-Sofayan M,Khalaf H,Al-Sebayel M,Al-Jedai A,Abdo A

更新日期：2011-06-01 00:00:00

abstract：:The original version of the article unfortunately contained an error in the surname of the second author, Dr. Ferdinando D'Amico in the author group. ...

journal_title：Digestive diseases and sciences

authors： Chateau T,D'Amico F,Zallot C,Mathieu N,Peyrin-Biroulet L

更新日期：2020-09-25 00:00:00

abstract：:Our objective was to determine whether there are dominating racial differences in patient preferences for surgery that may explain the disparities in proctocolectomy utilization between African Americans (AA) and whites. We used the time trade-off technique to measure health preferences for undergoing ileal pouch anal...

journal_title：Digestive diseases and sciences

authors： Nguyen GC,Tuskey A,Bayless TM,LaVeist TA,Brant SR

更新日期：2008-03-01 00:00:00

abstract：:Despite many studies on pain of functional gastrointestinal disorders (FGID), the pain mechanism of FGID is not well understood, and pain treatment of FGID is not established. Following our former functional dyspepsia (FD) study, we proposed two subgroups of patients with irritable bowel syndrome (IBS), pain and disco...

journal_title：Digestive diseases and sciences

authors： Handa M,Nukina H,Ando K,Kubo C

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:There are many studies on submucosal injection materials, but their clinical use is restricted for various reasons. The objective of this study was to compare the feasibility and safety of injected EndoClot®SIS polysaccharide as a submucosal injection material (SFC) in ESD in the pig stomach to that of injec...

journal_title：Digestive diseases and sciences

authors： Dai MS,Hu KW,Wu W,Yin GJ,Hu DM

更新日期：2019-10-01 00:00:00

abstract：:The time-dependent appearance of phospholipase A2 (PLA2) activity in the preservation media of ischemic rat intestinal grafts is described. In controls, Ca2+-dependent, secretory PLA2 activity accumulated rapidly during the first 6 hr of ischemia, followed by a linear increase for up to 48 hr. LDH levels, by contrast,...

journal_title：Digestive diseases and sciences

authors： Sonnino RE,Pigatt L,Schrama A,Burchett S,Franson R

更新日期：1997-05-01 00:00:00

abstract：:Idiopathic chronic constipation has been correlated to neural abnormalities that consist of a reduced number of myenteric plexus neurons and a decreased concentration of VIP-positive nerve fibers within the circular muscle. Recent studies hypothesized the involvement of nitric oxide in motility disorders of the human ...

journal_title：Digestive diseases and sciences

authors： Cortesini C,Cianchi F,Infantino A,Lise M

更新日期：1995-11-01 00:00:00

abstract：:Choledochoduodenostomy may be followed by the "sump syndrome." This previously required surgical intervention. We describe the successful application of endoscopic therapy in two patients with this syndrome. ...

journal_title：Digestive diseases and sciences

authors： Barkin JS,Silvis S,Greenwald R

更新日期：1980-08-01 00:00:00

abstract：:Two hundred one consecutive patients with gallstone disease who had undergone cholecystectomy were analyzed to determine the relative frequency of occurrence of cholesterol and pigment gallstones and to identify distinguishing features of the two stone types. Cholesterol stones (CS) formed the majority (94%) of gallst...

journal_title：Digestive diseases and sciences

authors： Sarin SK,Kapur BM,Tandon RK

更新日期：1986-10-01 00:00:00

abstract：BACKGROUND:The colon is partly controlled by myenteric and submucosal plexuses, which respond to stress and lead to some gastrointestinal disorders. These plexuses play roles in irritable bowel syndrome. Patients suffering from this syndrome can be treated with some antidepressants, including sertraline and nortriptyli...

journal_title：Digestive diseases and sciences

authors： Noorafshan A,Yousefi M,Hosseini L,Karbalay-Doust S

更新日期：2019-09-01 00:00:00

abstract：UNLABELLED:There is a wide choice of fecal occult blood tests (FOBTs) for colorectal cancer screening. GOAL:To highlight the issues applicable when choosing a FOBT, in particular which FOBT is best suited to the range of screening scenarios. Four scenarios characterize the constraints and expectations of screening pro...

journal_title：Digestive diseases and sciences

authors： Young GP,Symonds EL,Allison JE,Cole SR,Fraser CG,Halloran SP,Kuipers EJ,Seaman HE

更新日期：2015-03-01 00:00:00

abstract：:A muscarinic receptor subtype 1 (M1) antagonist, pirenzepine, recently has been shown to be relatively free of the usual anticholinergic side effects on esophageal smooth muscle and thus has been implicated for the treatment of gastroesophageal reflux disease (GERD). However, the effect of pirenzepine on GERD remains ...

journal_title：Digestive diseases and sciences

authors： Sato TL,Wu WC,Castell DO

更新日期：1992-02-01 00:00:00

abstract：:In a double-blind, randomized crossover study, the hypotheses were tested that more powerful inhibition of gastric acid secretion by adjuvant omeprazole further improves the efficacy of pancreatic enzyme replacement therapy compared to adjuvant cimetidine and that excluding the influence of pH-related factors, by virt...

journal_title：Digestive diseases and sciences

authors： Bruno MJ,Rauws EA,Hoek FJ,Tytgat GN

更新日期：1994-05-01 00:00:00

abstract：:The molecular mechanisms of Helicobacter pylori associated tumor development are poorly understood. The spectra of genetic alterations in neoplasms may provide clues to the molecular carcinogenesis of a tumor and may be relevant for the prognosis of the patients. We investigated the p53 mutation pattern and the protei...

journal_title：Digestive diseases and sciences

authors： Kubicka S,Claas C,Staab S,Kühnel F,Zender L,Trautwein C,Wagner S,Rudolph KL,Manns M

更新日期：2002-01-01 00:00:00

abstract：:A 68-year-old woman developed exfoliative dermatitis while taking cimetidine for gastritis. She had no history of previous drug reactions, allergies, or skin disorders and had taken no other medications for three months. Although cimetidine is a relatively safe drug, severe reactions such as exfoliative dermatitis can...

journal_title：Digestive diseases and sciences

authors： Yantis PL,Bridges ME,Pittman FE

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND:Ileocolic anastomosis is an essential step in the treatment to restore continuity of the gastrointestinal tract following ileocolic resection in patients with Crohn's disease (CD). However, the association between anastomotic type and surgical outcome is controversial. AIMS:The aim of this meta-analysis is ...

journal_title：Digestive diseases and sciences

authors： He X,Chen Z,Huang J,Lian L,Rouniyar S,Wu X,Lan P

更新日期：2014-07-01 00:00:00

abstract：:Turmeric is widely used in Indian cuisine. The main constituents of turmeric are curcumin and its analogues, which are well-known antioxidant compounds. In the present study, we hypothesized that turmeric in curry might increase bowel motility and activate hydrogen-producing bacterial flora in the colon, thereby incre...

journal_title：Digestive diseases and sciences

authors： Shimouchi A,Nose K,Takaoka M,Hayashi H,Kondo T

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), which are most abundant in the liver, are the main enzymes involved in ethanol and acetaldehyde metabolism. AIMS:The purpose of this study was to compare the activity of ADH isoenzymes and ALDH between liver carcinoma cells and healthy hepatocyt...

journal_title：Digestive diseases and sciences

authors： Jelski W,Zalewski B,Szmitkowski M

更新日期：2008-09-01 00:00:00

abstract：:Celiac disease (CD) is an immune-mediated enteropathy triggered by dietary ingestion of gluten in genetically susceptible patients. CD is often diagnosed by a "case-finding" approach of symptomatic patients. In recent times, the diagnostic paradigm has shifted to investigate patients who may be asymptomatic, but are a...

journal_title：Digestive diseases and sciences

authors： Kumral D,Syed S

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Determining the risk stratification of nonvariceal upper gastrointestinal bleeding (NVUGIB) plays a vital role in treating upper gastrointestinal bleeding (UGIB). Traditional scores like Glasgow-Blatchford score (GBS), Rockall score (RS), and AIMS65 score have been widely utilized in UGIB practice, however e...

journal_title：Digestive diseases and sciences

authors： Yue W,Liu Y,Jiang W,Huang J,Liu J

更新日期：2020-06-24 00:00:00

abstract：BACKGROUND:Triglyceride-rich lipoproteins are important in dietary lipid absorption and subsequent energy distribution in the body. Their importance in the gut-lymph may have been overlooked in sepsis, the most common cause of critical illness, and in gut ischemia-reperfusion injury, a common feature of many critical i...

journal_title：Digestive diseases and sciences

authors： Hong J,Nachkebia S,Tun SM,Petzer A,Windsor JA,Hickey AJ,Phillips AR

更新日期：2018-12-01 00:00:00