Pathways mediating pentagastrin-induced mucosal blood flow response in rat stomachs.

abstract：:Patients with Zollinger-Ellison syndrome whose gastric acid secretion or symptoms were not controlled by cimetidine in conventional dosage were selected for studies of responsiveness of their acid secretion to increasing doses of cimetidine, used either alone or in combination with a long-acting anticholinergic agent,...

journal_title：Digestive diseases and sciences

authors： McCarthy DM,Hyman PE

更新日期：1982-04-01 00:00:00

abstract：AIM:To investigate whether a diagnostic delay is associated with a poor outcome in Crohn's disease (CD). METHODS:Medical and socioeconomic characteristics as well as medications and need for surgery of consecutive CD adults patients followed in three referral centers were prospectively recorded using an electronic dat...

journal_title：Digestive diseases and sciences

authors： Nahon S,Lahmek P,Paupard T,Lesgourgues B,Chaussade S,Peyrin-Biroulet L,Abitbol V

更新日期：2016-11-01 00:00:00

abstract：:Glutamine synthetase is responsible for the ATP-dependent amidation of glutamate to glutamine. In liver the enzyme is highly localized in perivenous hepatocytes; in brain the enzyme is localized in astrocytes. Portacaval anastomosis resulted in liver atrophy, hyperammonemia, and up to 90% loss of glutamine synthetase ...

journal_title：Digestive diseases and sciences

authors： Girard G,Butterworth RF

更新日期：1992-07-01 00:00:00

abstract：:The susceptibility to sepsis in obstructive jaundice may be related to bacterial translocation (BT) from the gastrointestinal tract. We evaluated BT to visceral organs and morphological changes of the intestinal mucosa in a rat model of obstructive jaundice. Animals were randomly divided into two groups: in group A th...

journal_title：Digestive diseases and sciences

authors： Sileri P,Morini S,Sica GS,Schena S,Rastellini C,Gaspari AL,Benedetti E,Cicalese L

更新日期：2002-04-01 00:00:00

abstract：:Sumatriptan, a 5-HT1-receptor agonist has been shown to delay gastric emptying of liquids and solids in humans. However, no data are available of the effect of sumatriptan on gastric adaptation after distension with liquids and on symptoms induced by gastric distension. In 23 normal subjects and 30 dyspeptic patients ...

journal_title：Digestive diseases and sciences

authors： Malatesta MG,Fascetti E,Ciccaglione AF,Cappello G,Grossi L,Ferri A,Marzio L

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Two of the foremost issues in screening colonoscopy involve delivering quality and maximizing adenoma detection rates (ADR). Little is known about the impact of deep sedation on ADR. This study aims to compare the detection of advanced lesions during screening colonoscopy performed with moderate con...

journal_title：Digestive diseases and sciences

authors： Wang A,Hoda KM,Holub JL,Eisen GM

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Obesity and diabetes are risk factors for advanced alcoholic liver disease, and both are components of the metabolic syndrome. We aimed to assess the prevalence of metabolic syndrome and its components in a contemporary US cohort of adults with alcoholic liver disease and compare it to a historic co...

journal_title：Digestive diseases and sciences

authors： Singh A,Amin H,Garg R,Gupta M,Lopez R,Alkhouri N,MCCullough A

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Studies examining the mortality risk of inflammatory bowel disease (IBD) have yielded conflicting results, and most do not account for recent advancements made in the treatment of Crohn's disease (CD) and ulcerative colitis (UC). We aim to assess the overall, premature, and cause-specific mortality in IBD pa...

journal_title：Digestive diseases and sciences

authors： Nocerino A,Feathers A,Ivanina E,Durbin L,Swaminath A

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:The pathogenesis and treatment of ulcerative colitis remain poorly understood. The aim of the present study is to investigate the effects of black cumin (Nigella sativa) oil on rats with colitis. METHODS:Experimental colitis was induced with 1 mL trinitrobenzene sulfonic acid (TNBS) in 40% ethanol by intrac...

journal_title：Digestive diseases and sciences

authors： Isik F,Tunali Akbay T,Yarat A,Genc Z,Pisiriciler R,Caliskan-Ak E,Cetinel S,Altıntas A,Sener G

更新日期：2011-03-01 00:00:00

abstract：:The effect of psyllium hydrophilic mucilloid (PHM) when used as a laxative and/or stool softener on serum cholesterol concentrations was examined in 176 ambulatory elderly participants attending a health screening program. The change in one-year serum cholesterol concentration in subjects using PHM was compared with t...

journal_title：Digestive diseases and sciences

authors： Stewart RB,Hale WE,Moore MT,May FE,Marks RG

更新日期：1991-03-01 00:00:00

abstract：:The liver is recognized as a sex hormone-responsive organ. Gender-specific differences in liver function are known to exist. Recently, a higher failure rate for organs transplanted in adults from female donors to male recipients has been reported. This increased failure rate of livers obtained from adult females and t...

journal_title：Digestive diseases and sciences

authors： Pillay P,Van Thiel DH,Gavaler JS,Starzl TE

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND AND AIMS:The Gastroenterology Core Curriculum requires training in women's digestive disorders; however, requirements do not necessarily produce knowledge and competence. Our study goals were: (1) to compare perceptions of education, fellow-reported levels of competence, and attitudes towards training in wom...

journal_title：Digestive diseases and sciences

authors： Saha S,Roberson E,Richie K,Lindstrom MJ,Esposti SD,Wald A

更新日期：2011-03-01 00:00:00

abstract：:The effects of deoxycholic acid (DCA) on the intestinal microbiota, bile acid (BA) metabolism, and intestinal epithelium can be influenced by various factors. Depending on the specific conditions, DCA can be "bad" (proinflammatory) or "good" (anti-inflammatory). Mouse models of colitis show an increase in conjugated B...

journal_title：Digestive diseases and sciences

authors： Sitkin S,Pokrotnieks J

更新日期：2020-10-16 00:00:00

abstract：BACKGROUND:MicroRNA is essential for the malignant progression of human gastric cancer (GC), which is a leading cause of cancer deaths. However, the mechanism is still not so clear. AIMS:In our present research, we investigated the effect of miR-9-5p in GC. METHODS:We detected miR-9-5p expression in human gastric epi...

journal_title：Digestive diseases and sciences

authors： Fan Y,Shi Y,Lin Z,Huang X,Li J,Huang W,Shen D,Zhuang G,Liu W

更新日期：2019-10-01 00:00:00

abstract：:Clinical features and liver biopsy findings were studied in six patients with nonalcoholic steatohepatitis associated with hyalin. A comparative study was made on the ultrastructure of the hyalin in one patient with nonalcoholic steatohepatitis and in one patient with alcoholic hepatitis. The patients, all over 50 yea...

journal_title：Digestive diseases and sciences

authors： Itoh S,Matsuo S,Ichinoe A,Yamaba Y,Miyazawa M

更新日期：1982-04-01 00:00:00

abstract：:The oral intake of food is important for the observed compensatory hyperplasia in the remnant small intestine after resection but the molecular events governing this response are not known. Peptides, of molecular weight 4500 and 1000 daltons, present in the the proximal intestine for 96 hr after resection and mitogeni...

journal_title：Digestive diseases and sciences

authors： Grey VL,Morin CL

更新日期：1988-01-01 00:00:00

abstract：:Both increased duodenogastric reflux and chronic aspirin ingestion are associated with the development of gastric ulcers in man. Animal studies suggest aspirin increases duodenogastric reflux. Prostaglandin E2 protects gastric mucosa from the effects of many injurious agents and inhibits gastric motility, but its effe...

journal_title：Digestive diseases and sciences

authors： Dooley CP,Mello WD,Valenzuela JE

更新日期：1985-06-01 00:00:00

abstract：:Breath methane was studied in 394 subjects. Among 152 controls, 50.0% produced methane--42.1% of males and 57.9% of females. One hundred sixteen patients with gastrointestinal diseases were studied. Among 32 with Crohn's disease, only 2 (6.1%) produced methane, as well as 16 of 51 ulcerative colitis patients (31.4%) a...

journal_title：Digestive diseases and sciences

authors： Peled Y,Weinberg D,Hallak A,Gilat T

更新日期：1987-03-01 00:00:00

abstract：:Cytomegalovirus (CMV) inclusions were found at colonic perforation sites in three patients with clinical settings suggesting a compromised immunologic status. This could be interpreted as: (1) CMV was an etiologic agent in these perforations; or (2) CMV was an opportunistic superinfection in areas of preexisting infla...

journal_title：Digestive diseases and sciences

authors： Goodman ZD,Boitnott JK,Yardley JH

更新日期：1979-05-01 00:00:00

abstract：BACKGROUND AND AIM:Self-expandable metal stents (SEMSs) have been a good treatment option for malignant intestinal obstruction. However, stent placement with a gastroscope can be technically difficult for the distal duodenum obstruction. A side-viewing duodenoscope may be helpful for these patients. We report our exper...

journal_title：Digestive diseases and sciences

authors： Park JM,Min BH,Lee SH,Chung KH,Lee JM,Song BJ,Lee JK,Ryu JK,Kim YT

更新日期：2015-02-01 00:00:00

abstract：:Azithromycin (Zithromax), an erythromycin derivative that belongs to a subgroup of the macrolides known as azolides, has generally been considered to be a very safe medication. Hepatic side effects are uncommon but may include jaundice, fever, and right upper quadrant pain. Herein we describe a patient who developed a...

journal_title：Digestive diseases and sciences

authors： Chandrupatla S,Demetris AJ,Rabinovitz M

更新日期：2002-10-01 00:00:00

abstract：:We have previously shown that methane on lactulose breath test (LBT) is highly associated with constipation in IBS and that methane gas itself slows small bowel transit in dogs. Previous studies suggest that serotonin may have a role in the control of transit in IBS. In this study, we aim to evaluate the role of serot...

journal_title：Digestive diseases and sciences

authors： Pimentel M,Kong Y,Park S

更新日期：2004-01-01 00:00:00

abstract：:The aim of this study was to examine the effect of the antithrombotic drugs aspirin and enoxaparin on fibrosis progression and regenerative activity in a rat model of liver cirrhosis and to determine if these two drugs are beneficial in animals with advanced fibrosis or with established cirrhosis undergoing partial he...

journal_title：Digestive diseases and sciences

authors： Assy N,Hussein O,Khalil A,Luder A,Szvalb S,Paizi M,Spira G

更新日期：2007-05-01 00:00:00

abstract：:Squamous cell carcinoma represents the most common primary malignant lesion of the esophagus (1). The initial manifestation of lymphosarcoma infrequently occurs in the gastrointestinal tract, and in one large series, there were no lymphosarcomas presenting in the esophagus (2). In the case described below, a primary h...

journal_title：Digestive diseases and sciences

authors： Berman MD,Falchuk KR,Trey C,Gramm HF

更新日期：1979-11-01 00:00:00

abstract：:Twelve partially gastrectomized subjects who have consecutively undergone total biliary diversion for severe bilious vomiting were studied before and after operation in order to assess the effects of surgery on gastric histology and enterogastric reflux. Before and six months after operation, the following protocol wa...

journal_title：Digestive diseases and sciences

authors： Bechi P,Amorosi A,Mazzanti R,Buccarelli A,Pantalone D,Cortesini C

更新日期：1988-10-01 00:00:00

abstract：:The objective of this study was to determine if HCV can be transmitted from patient to patient in psychiatric institutions and to determine possible routes of infection. We did a cross-sectional survey of 196 Japanese psychiatric patients tested for HCV and HBV markers and 400 age- and sex-matched controls. Anti-HCV w...

journal_title：Digestive diseases and sciences

authors： Sawayama Y,Hayashi J,Kakuda K,Furusyo N,Ariyama I,Kawakami Y,Kinukawa N,Kashiwagi S

更新日期：2000-02-01 00:00:00

abstract：:As chronic liver disease progresses, an imbalance occurs between synthesis and breakdown of extracellular matrix (ECM). Matrix metalloproteinases (MMPs) are involved in degrading ECM while tissue inhibitors of metalloproteinases (TIMPs) prevent their fibrolytic action. We determined if plasma levels of MMP-2, TIMP-1 a...

journal_title：Digestive diseases and sciences

authors： Walsh KM,Timms P,Campbell S,MacSween RN,Morris AJ

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Esophageal stricture is one of the serious adverse events following endoscopic submucosal dissection (ESD). However, optimum preventive techniques are still lacking. AIMS:Our primary objective was to evaluate the incidence of post-ESD esophageal stricture with the application of carboxymethyl cellulose (CMC...

journal_title：Digestive diseases and sciences

authors： Lua GW,Tang J,Liu F,Li ZS

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Double-balloon enteroscopy (DBE) is a safe and useful procedure for managing small bowel bleeding. However, there are limited studies regarding the preferable timing of DBE and its impact on long-term outcomes. AIM:We aimed to evaluate the association between the timing of DBE and the long-term outcomes of ...

journal_title：Digestive diseases and sciences

authors： Hashimoto R,Nakahori M,Matsuda T

更新日期：2019-10-01 00:00:00

abstract：:Translocation of bacteria and endotoxtin has long been documented in obstructive jaundice, and altered intestinal barrier function is considered to be one of the important mechanisms for this phenomenon. The regulation of gastrointestinal mucosal response to injury is thus of important clinical as well as biological r...

journal_title：Digestive diseases and sciences

authors： Sheen-Chen SM,Chen HS,Ho HT,Sheen CC,Chen WJ,Eng HL

更新日期：2003-06-01 00:00:00