Chronic intestinal pseudoobstruction with myopathy and ophthalmoplegia. A muscular biochemical study of a mitochondrial disorder.

Abstract:

:The association of chronic intestinal pseudoobstruction with ophthalmoplegia has been reported previously in visceral myopathies. We report a case of this association in which muscle mitochondria had a crystalline appearance, a dense core, and decreased cytochrome c oxidase and succinate cytochrome c reductase activities. The absence of evident mitochondrial DNA deletion in the skeletal muscle of this patient does not exclude the possibility of localized deletion or mutation of mitochondrial DNA in digestive muscle.

journal_name

Dig Dis Sci

authors

Li V,Hostein J,Romero NB,Marsac C,Mezin P,Bost R,Degoul F,Fardeau M,Fournet J

doi

10.1007/BF01307743

subject

Has Abstract

pub_date

1992-03-01 00:00:00

pages

456-63

issue

3

eissn

0163-2116

issn

1573-2568

journal_volume

37

pub_type

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