Abstract:
:Studies have shown a promoting effect of food on small intestinal absorption. Casein hydrolysate seems be more effective in increasing of D-xylose absorption in dogs than the whole protein and lactulose. The purpose this study was to analyze the effect of groups of peptides derived from casein hydrolysate on the absorption of D-Xylose and intestinal transit time in normal subjects. Seven normal volunteers participated in the study. Three peptide fractions were isolated from casein enzymatic hydrolysate by means of a preparative HPLC silica column. On separate days subjects drank test solutions containing lactulose, D-xylose, and D-xylose with one of three peptide groups. The hydrogen breath test was used to indirectly estimate D-xylose absorption and orocecal transit time. Two peptide fractions when added to D-xylose were followed by an increased absorption characterized by decreased H2 production. A nonstatistically significant increase of orocecal transit time was observed with these peptides.
journal_name
Dig Dis Scijournal_title
Digestive diseases and sciencesauthors
Defilippi C,Madrid AM,Salas K,Michea L,Lagos Ndoi
10.1023/a:1005439525762subject
Has Abstractpub_date
2000-04-01 00:00:00pages
705-9issue
4eissn
0163-2116issn
1573-2568journal_volume
45pub_type
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