Zika virus research models.

abstract：:At present there is much interest in the cell tropism and host range of influenza viruses, especially those of the H5N1 subtype. We wished to develop a method that would enable investigation of attachment of infectious virus through the interaction of the hemagglutinin molecule and live mammalian and avian cells and t...

journal_title：Virus research

authors： Rimmelzwaan GF,Nieuwkoop NJ,de Mutsert G,Boon AC,Kuiken T,Fouchier RA,Osterhaus AD

更新日期：2007-11-01 00:00:00

abstract：:Three dendrimeric peptides were synthesized in order to evaluate their immunogenicity and their potential protection against classical swine fever virus (CSFV) in domestic pigs. Construct 1, an optimized version of a previously used dendrimer, had four copies of a B-cell epitope derived from CSFV E2 glycoprotein conne...

journal_title：Virus research

authors： Bohórquez JA,Defaus S,Muñoz-González S,Perez-Simó M,Rosell R,Fraile L,Sobrino F,Andreu D,Ganges L

更新日期：2017-06-15 00:00:00

abstract：:In present study, we report the first complete genomic sequence of pig bovine viral diarrhea (BVD) virus, that of strain ZM-95, which is 12,220 nucleotides long and contains short 5' and 3' non-coding regions and one open reading frame encoding a large polyprotein with 28 potential N-glycosylation sites (Asn-X-Ser or ...

journal_title：Virus research

authors： Xu X,Zhang Q,Yu X,Liang L,Xiao C,Xiang H,Tu C

更新日期：2006-12-01 00:00:00

abstract：:MicroRNAs (miRNAs) play important roles in viral infections, especially by modulating the expression of cellular factors essential to viral replication or the host innate immune response to infection. To identify host miRNAs important to controlling porcine reproductive and respiratory syndrome virus (PRRSV) infection...

journal_title：Virus research

authors： Li L,Wei Z,Zhou Y,Gao F,Jiang Y,Yu L,Zheng H,Tong W,Yang S,Zheng H,Shan T,Liu F,Xia T,Tong G

更新日期：2015-01-02 00:00:00

abstract：:Polyomavirus VP1 has been shown to be modified by phosphorylation, sulfation, acetylation and hydroxylation. The major capsid protein VP1 is now shown to be modified by methylation. Addition of cycloheximide to infected cultures followed by addition of [3H-methyl]-L-methionine and subsequent immunoprecipitation, SDS-P...

journal_title：Virus research

authors： Burton KS,Consigli RA

更新日期：1996-02-01 00:00:00

abstract：:While large-scale dog vaccination campaigns have significantly reduced urban rabies throughout Mexico, reports of sylvatic rabies, including cases of spill-over of bat strains into livestock and humans, are increasing. To improve knowledge of these epidemiological trends, 64 Mexican rabies virus isolates from various ...

journal_title：Virus research

authors： Nadin-Davis SA,Loza-Rubio E

更新日期：2006-05-01 00:00:00

abstract：:Raccoons (Procyon lotor), which are not native to Japan, have been suspected to transmit various pathogens by frequent intrusion into agricultural and residential areas. To determine influenza A virus seropositivity in raccoons in Japan, we examined a total of 634 raccoons captured in 19 towns (A-S) from 2009 to 2012....

journal_title：Virus research

authors： Yamaguchi E,Sashika M,Fujii K,Kobayashi K,Bui VN,Ogawa H,Imai K

更新日期：2014-08-30 00:00:00

abstract：:The genomic RNA of vitiviruses contains 5 open reading frames (ORF). ORF3 encodes a protein to which the function of a movement protein (MP) was assigned, based on sequence homology with other viral proteins. The aim of the research described in this paper was to gain further insight in distribution profile of the ORF...

journal_title：Virus research

authors： Haviv S,Moskovitz Y,Mawassi M

更新日期：2012-01-01 00:00:00

abstract：:Porcine reproductive and respiratory syndrome virus (PRRSV) induces apoptosis in cultured cells and in infected tissues of pig, and the GP5 protein was reported to be responsible. To study the role of apoptosis during PRRSV infection, we established a subline of HeLa cells stably expressing the PRRSV GP5 protein under...

journal_title：Virus research

authors： Lee C,Rogan D,Erickson L,Zhang J,Yoo D

更新日期：2004-08-01 00:00:00

abstract：:In this study, we tried to identify dengue virus-specific CD4(+) T-cell epitopes, which can induce PBMC (peripheral blood mononuclear cells) isolated from DF convalescent patients (dengue virus type 1 infection) to secrete IFN-gamma. PBMC of DF convalescent patients were stimulated in vitro with dengue virus-derived p...

journal_title：Virus research

authors： Wen JS,Jiang LF,Zhou JM,Yan HJ,Fang DY

更新日期：2008-03-01 00:00:00

abstract：:We have found that an HIV-1 accessory gene product Vpr enhanced HIV-1 reproduction in U1 cells chiefly by the induction of TNF, a proinflammatory cytokine, which was also known to be an activator of HIV-1 reproduction. We have generated the functional HIV-1 accessory gene product Vpr in bacterial cells. Vpr was genera...

journal_title：Virus research

authors： Nakamura T,Suzuki H,Okamoto T,Kotani S,Atsuji Y,Tanaka T,Ito Y

更新日期：2002-12-01 00:00:00

abstract：:The nature of the interaction between papillomaviruses (PV) and their infected host has led to the identification of ways in which the viral oncoproteins can transform the infected host cells into cancer cells. As viral persistence is required for malignancy, and persistence requires avoidance of immune attack by the ...

journal_title：Virus research

authors： O'Brien PM,Saveria Campo M

更新日期：2002-09-01 00:00:00

abstract：:The paramyxo- and pneumoviruses are members of the order Mononegavirales, a group of viruses with non-segmented, negative strand RNA genomes. The polymerases of these viruses are multi-functional complexes, capable of transcribing subgenomic capped and polyadenylated mRNAs and replicating the genome. Although there is...

journal_title：Virus research

authors： Fearns R,Plemper RK

更新日期：2017-04-15 00:00:00

abstract：:The K1L protein of vaccinia virus is required for its growth in certain cell lines (RK-13 and human). The cowpox host-range protein CP77 has been shown to complement K1L function in RK-13 cells, despite a lack of homology between the two proteins except for ankyrin repeats. We investigated the role of ankyrin repeats ...

journal_title：Virus research

authors： Bradley RR,Terajima M

更新日期：2005-12-01 00:00:00

abstract：:Since February 2013, H7N9 influenza virus, causing human infections with high mortality in China, has been a potential pandemic threat. The H7N9 viruses are found to diverge into distinct genotypes as other influenza viruses; thus a vaccine that can provide sufficient cross-protection against different genotypes of H7...

journal_title：Virus research

authors： Wang Y,Zhang Y,Wu J,Lin Y,Wu Z,Wei Y,Wei X,Qin J,Xue C,Liu GD,Cao Y

更新日期：2017-10-15 00:00:00

abstract：:Enterovirus 71 (EV71) is a single-stranded RNA virus that belongs to Picornaviridae family. It causes the hand-foot-and-mouth disease and fatal neurological diseases in young children and infants. The mechanism of EV71 pathogenesis remains obscure. The intestinal tract is the initial site of EV71 replication, but no o...

journal_title：Virus research

authors： Chi C,Sun Q,Wang S,Zhang Z,Li X,Cardona CJ,Jin Y,Xing Z

更新日期：2013-09-01 00:00:00

abstract：:Influenza A virus replication and packaging is mediated by cis-acting signals, which are located at the 3' and the 5' end of the viral segments. The terminal residues can be divided into conserved and nonconserved residues. We have constructed a mutant influenza A/WSN/33 virus, which contains multiple mutations in the...

journal_title：Virus research

authors： Bergmann M,Muster T

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:HTLV-2 infections are almost always asymptomatic, and diseases associated with the infection are rarely reported. Little information is available on the relationship between HTLV-2 proviral load and gender or expression of disease, especially among patients with HIV-1 co-infection. METHODS:We studied 77 HTL...

journal_title：Virus research

authors： Montanheiro P,Olah I,Fukumori LM,Smid J,Oliveira AC,Kanzaki LI,Fonseca LA,Duarte AJ,Casseb J

更新日期：2008-07-01 00:00:00

abstract：:An account is given of progress during the last 30 years in knowledge of the epidemiology of diseases caused by aphid-borne viruses in seed potato production areas of northern Europe. During this period, Potato leafroll virus (PLRV) and strains of Potato virus Y (PVY(O), PVY(N)) were consistently the most prevalent an...

journal_title：Virus research

authors： Robert Y,Woodford JA,Ducray-Bourdin DG

更新日期：2000-11-01 00:00:00

abstract：:Marek's disease virus (MDV) is a lymphotropic alphaherpesvirus and causes Marek's disease (MD) in chickens. RLORF4 is an MDV-specific gene located in the repeat long (RL) regions of the genome and is directly involved in attenuation. In this report, we generated recombinant (r)MDVs in which eGFP or mRFP was inserted i...

journal_title：Virus research

authors： Jarosinski KW,Donovan KM,Du G

更新日期：2015-04-02 00:00:00

abstract：:Despite the fact that cells infected with wild type vaccinia virus synthesize viral DNA and assemble progeny virus particles within the cytoplasm, the host cell nucleus is required for a productive infection. Recent evidence suggests that vaccinia virus selectively recruits components from the host cell nucleus into t...

journal_title：Virus research

authors： Moyer RW

更新日期：1987-09-01 00:00:00

abstract：:Fifteen stable mouse spleen cell myeloma hybrids (hybridomas) producing monoclonal antibodies to rinderpest virus proteins were produced. The specificity of these monoclonal antibodies was established by radioimmunoprecipitation followed by polyacrylamide gel analysis and immunofluorescence. Nine antibodies were speci...

journal_title：Virus research

authors： Bhavani K,Karande AA,Shaila MS

更新日期：1989-04-01 00:00:00

abstract：:A cell-free system was developed to study the replication of simian rotavirus SA11. The components of the system included (i) subviral particles prepared from infected cells to template the synthesis of viral RNA and (ii) an mRNA-dependent rabbit reticulocyte lysate to support protein synthesis. Based upon nuclease-se...

journal_title：Virus research

authors： Patton JT

更新日期：1986-12-01 00:00:00

abstract：:The fidelity of poliovirus RNA-dependent RNA polymerase (3D(pol)) was determined using a system based on the fidelity of synthesis of the alpha-lac gene which codes for a subunit of beta-galactosidase. Synthesis products are screened for mutations by an alpha-complementation assay, in which the protein product from al...

journal_title：Virus research

authors： Wells VR,Plotch SJ,DeStefano JJ

更新日期：2001-04-01 00:00:00

abstract：:The nucleotide sequence of the matrix gene (M) of a recently identified morbillivirus, phocid distemper virus (PDV), was determined and the amino acid composition deduced. The M gene of PDV shared many characteristics with the corresponding gene in other morbilliviruses. The nucleotide homology with the closely relate...

journal_title：Virus research

authors： Sharma B,Norrby E,Blixenkrone-Möller M,Kövamees J

更新日期：1992-04-01 00:00:00

abstract：:Hand, foot and mouth disease (HFMD) in humans is caused mainly by Enterovirus 71(EV71) and Coxsackievirus A16 (CVA16). EV71 is associated with severe HFMD cases but not CVA16. Use of IgM-capture enzyme-linked immunosorbent assay (ELISA) is important for the early diagnosis of EV71 infection, but cross-reactivity of th...

journal_title：Virus research

authors： Wang C,You A,Tian X,Zhao M,Chen Y,Lin T,Zheng J,Xiao M,Zhang Y,Kuang L,Zhou Z,Zhu B

更新日期：2013-09-01 00:00:00

abstract：:Atlantic salmon paramyxovirus (ASPV) was isolated in 1995 from gills of farmed Atlantic salmon suffering from proliferative gill inflammation. The complete genome sequence of ASPV was determined, revealing a genome 16,968 nucleotides in length consisting of six non-overlapping genes coding for the nucleo- (N), phospho...

journal_title：Virus research

authors： Falk K,Batts WN,Kvellestad A,Kurath G,Wiik-Nielsen J,Winton JR

更新日期：2008-05-01 00:00:00

abstract：:RNA species of plant tripartite RNA viruses show distinct translational activities in vitro when the viral RNA concentration is high. However, it is not known what causes the differential translation of virion RNAs. Using an in vitro wheat germ translation system, we investigated the translation efficiencies and compe...

journal_title：Virus research

authors： Kwon CS,Chung WI

更新日期：2000-02-01 00:00:00

abstract：:Recombinant clones containing all or portions of the bovine papillomavirus (BPV) upstream regulatory region (URR) were constructed. When analyzed by polyacrylamide gel electrophoresis, the cloned URR sequences exhibited electrophoretic properties characteristic of DNA containing bend sites. Two distinct bend centers w...

journal_title：Virus research

authors： Wilson VG

更新日期：1989-05-01 00:00:00

abstract：:Porcine reproductive and respiratory syndrome (PRRS) is a major disease affecting pigs worldwide and resulting in considerable economic losses. While PRRS is a global phenomenon, the causative viruses PRRSV-1 (first detected in Europe) and PRRSV-2 (isolated in North America) are genetically and biologically distinct. ...

journal_title：Virus research

authors： Salguero FJ,Frossard JP,Rebel JM,Stadejek T,Morgan SB,Graham SP,Steinbach F

更新日期：2015-04-16 00:00:00