Abstract：
:Polyomavirus VP1 has been shown to be modified by phosphorylation, sulfation, acetylation and hydroxylation. The major capsid protein VP1 is now shown to be modified by methylation. Addition of cycloheximide to infected cultures followed by addition of [3H-methyl]-L-methionine and subsequent immunoprecipitation, SDS-PAGE and fluorography revealed methylation occurring on VP1. Amino acid analysis of [3H-methyl]-L-methionine-labelled polyomavirus VP1 by two-dimensional paper chromatography and HPLC of the acid-hydrolyzed protein revealed the presence of 3H-labelled trimethyllysine and monomethylarginine.
journal_name
Virus Resjournal_title
Virus researchauthors
Burton KS,Consigli RAdoi
10.1016/0168-1702(95)01266-4subject
Has Abstractpub_date
1996-02-01 00:00:00pages
141-7issue
2eissn
0168-1702issn
1872-7492pii
0168170295012664journal_volume
40pub_type
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