Effect of Peripheral μ-, δ-, and κ-Opioid Ligands on the Development of Tolerance to Ethanol-Induced Analgesia.

abstract：:We studied the correlation between the rank and age of baboons (n=12) with their cognitive abilities. A positive correlation was found between performances of different tests by male. The ability to solve the tests related to bait placement depended on the age of the males and age-related hierarchical status. Four-yea...

journal_title：Bulletin of experimental biology and medicine

authors： Anikaev AE,Chalyan VG,Meishvili NV

更新日期：2018-08-01 00:00:00

abstract：:The hypolipidemic effect of Kwai, a preparation based on garlic powder (Allium sativum), depended on the initial content of cholesterol and/or triglycerides. This effect was most pronounced in patients with coronary heart disease with initial cholesterol >7.0 mmol/liter and triglyceride >1.92 mmol/liter. After treatme...

journal_title：Bulletin of experimental biology and medicine

authors： Chernyad'eva IF,Shil'nikova SV,Rogoza AN,Kukharchuk VV

更新日期：2003-05-01 00:00:00

abstract：:We measured activity of angiotensin-converting enzyme in plasma and tissue of NISAG and normotensive WAG rats. In different organs of NISAG rats, activity of this enzyme did not differ from the corresponding values of WAG rats, although enzyme activity in the plasma of NISAG rats was significantly lower than that of W...

journal_title：Bulletin of experimental biology and medicine

authors： Cherkasova OP,Fedorov VI,Markel AL

更新日期：2005-10-01 00:00:00

abstract：:We studied the effects of cholesterol, its oxidized derivatives mevalonate, and nuclear receptor agonists LXR, RXR, and FXR on the production of transforming growth factor-beta1 (TGF- beta1) by macrophages. After recruiting of macrophage monocytes into the focus of inflammation, the production of TGF-beta1 increased b...

journal_title：Bulletin of experimental biology and medicine

authors： Schwartz YSh,Khoshchenko OM,Dushkin MI,Feofanova NA

更新日期：2009-09-01 00:00:00

abstract：:The effects of norepinephrine on the heart rate were studied in 1-, 3-, 6-, and 20-week-old rats before and after blockade of hyperpolarization-activated currents (I f , I h ). In animals with mature sympathetic regulation of cardiac activity (6- and 20-week-old animals), I f blockage decreased the severity of norepin...

journal_title：Bulletin of experimental biology and medicine

authors： Ziyatdinova NI,Dement'eva RE,Khisamieva LI,Zefirov TL

更新日期：2013-11-01 00:00:00

abstract：:We studied the mechanisms of induction of recombinase activity in peripheral T cells of patients with autoimmune type 1 diabetes mellitus. It was shown that the presence of CD40 on T cell membrane (not typical of these cells) is crucial for this process: expression of recombinase RAG-1 in diabetic patients was detecte...

journal_title：Bulletin of experimental biology and medicine

authors： Kuklina EM,Gorbunova OL,Smirnova EN

更新日期：2012-01-01 00:00:00

abstract：:Dihydroquercetin (flavonoid of plant origin) immobilized with an amino acid in lecithin nanoparticles promotes reduction of inflammatory reactions in the wound after thermal burn. The use of a liposomal complex in burn injury stabilizes endogenous antioxidant system and limits the secondary necrotic zone in the wounds...

journal_title：Bulletin of experimental biology and medicine

authors： Naumov AA,Shatalin YV,Potselueva MM

更新日期：2010-07-01 00:00:00

abstract：:In patients with viral and bacterial infectious mononucleosis during the acute period of disease and clinical convalescence blood content of CD72(+)and CD16(+)lymphocytes increased compared to normal. The count of CD8(+)cells increased in viral mononucleosis during convalescence and these changes persist in delayed pe...

journal_title：Bulletin of experimental biology and medicine

authors： Novitskii VV,Urazova OI,Naslednikova IO,Pomogaeva AP,Syusina LV

更新日期：2002-07-01 00:00:00

abstract：:Preliminary injection of succinic semialdehyde into animals in experiments with hypoxia led to a lower concentration of free ammonia in their brain tissues than in control experiments in which the compound was not given. The enzyme system of the liver tissue catalyzes the oxidation of NAD-H-2 by succinic semialdeyde a...

journal_title：Bulletin of experimental biology and medicine

authors： Zubovskaya AM,Ostrovskaya RU,Tsybina NM

更新日期：1975-01-01 00:00:00

abstract：:Activation of lysosomal proteolysis and increased coenzyme Q10 level were revealed in the liver and brain of rats with individual typological features under conditions of food deprivation. Changes in cathepsin B activity in these tissues were different in behaviorally active and passive animals. We observed indirect m...

journal_title：Bulletin of experimental biology and medicine

authors： Kirbaeva NV,Sharanova NE,Zhminchenko VM,Vasil'ev AV

更新日期：2018-07-01 00:00:00

abstract：:We studied properties of bacterial biofilms during long-term culturing. The biofilms were preserved for more than 90 days under the chosen conditions. At the same time, amounts of matrix and cells underwent periodic changes. The biomass of the biofilms decreased approximately every 7 days and then returned to the prev...

journal_title：Bulletin of experimental biology and medicine

authors： Tetz GV,Artemenko NK,Zaslavskaya NV,Tetz VV

更新日期：2013-08-01 00:00:00

abstract：:The morphology of neural and glial cells in different cerebral areas and in various experimental models was quantitatively studied by methods of computer morphometry combined with video image analysis systems. The following parameters were obtained: density of neurons and glial cells per 1 mm(2), number of satellite p...

journal_title：Bulletin of experimental biology and medicine

authors： Khudoerkov RM,Voronkov DN

更新日期：2010-07-01 00:00:00

abstract：:Nanocrystalline particles of chitin in the form of hydrosol in a concentration of 0.63 mg/ml have no effect on aggregation of human platelets and clotting time of platelet-poor plasma in coagulation tests. ADP-induced aggregation of human platelets was inhibited by these nanoparticles in concentrations of 0.63 and 1.0...

journal_title：Bulletin of experimental biology and medicine

authors： Drozd NN,Torlopov MA,Udoratina EV,Logvinova YS

更新日期：2018-04-01 00:00:00

abstract：:We studied competitive activities of 16 alpha,17 alpha-cyclohexano-5 alpha- and 5 beta-dihydroprogesterone in replacing(3)H-progesterone and(3)H-16 alpha,17 alpha-cyclohexano-6 alpha-methylprogesterone from protein complexes. Direct binding of(3)H-5-reduced derivatives with proteins of soluble fractions from rat and r...

journal_title：Bulletin of experimental biology and medicine

authors： Smirnov AN,Pokrovskaya EV,Levina IS,Kulikova LE,Kamernitskii AV,Shevchenko VP

更新日期：2001-03-01 00:00:00

abstract：:Comparative analysis of the efficiency of PCR and microbiological methods for deciphering of the etiological structure of non-nosocomial pneumonias demonstrated the diagnostic significance of detecting Streptococcus pneumoniae DNA in the blood, but not sputum. Mechanisms of penetration of S. pneumoniae into the blood ...

journal_title：Bulletin of experimental biology and medicine

authors： Artemova LV,Beskhlebnaya VA,Ezhova LG,Kirillov MY,Kravtsov EG,Dalin MV

更新日期：2003-10-01 00:00:00

abstract：:JAK/STAT signaling pathway was examined comparatively during realization of growth potential of mesenchymal progenitor cells stimulated with diterpene alkaloid songorine or fibroblast growth factor. The stimulating role of JAKs and STAT3 on the mitotic activity and differentiation of progenitor cells cultured with son...

journal_title：Bulletin of experimental biology and medicine

authors： Zyuz'kov GN,Udut EV,Miroshnichenko LA,Polyakova TY,Simanina EV,Stavrova LA,Prosekin GA,Zhdanov VV,Udut VV

更新日期：2018-09-01 00:00:00

abstract：:Data are presented on chemical study of flavonoid glycosides in some botanical subjects using matrix-assisted laser desorption ionization, compared to HPLC. The method of matrix-assisted laser desorption ionization (MALDI) allows characterizing the composition of anthocyanin and flavonoid mixture without preliminary s...

journal_title：Bulletin of experimental biology and medicine

authors： Novikov OO,Pisarev DI,Zhilyakova ET,Novikova MY,Pisareva NA,Voronkova OS,Bezmenova MD

更新日期：2013-01-01 00:00:00

abstract：:We studied the effect of 10-week treatment with intranasal insulin (0.5 IU/day) on glucose tolerance, glucose utilization, lipid metabolism, functions of pancreatic β cells, and insulin system in the liver of rats with cafeteria diet-induced metabolic syndrome. The therapy reduced body weight and blood levels of insul...

journal_title：Bulletin of experimental biology and medicine

authors： Derkach KV,Ivantsov AO,Chistyakova OV,Sukhov IB,Buzanakov DM,Kulikova AA,Shpakov AO

更新日期：2017-06-01 00:00:00

abstract：:Experiments on the model of thermal skin burn in rats showed that the use of wound dressing based on collagen-chitosan complex Kollakhit-Bol in local treatment of grade IIIb skin burns increased healing rate by accelerating the formation of granulation and fibrous connective tissues and reducing crust thickness in com...

journal_title：Bulletin of experimental biology and medicine

authors： Kirichenko AK,Bolshakov IN,Ali-Riza AE,Vlasov AA

更新日期：2013-03-01 00:00:00

abstract：:Infection of surfagon (gonadotropin-releasing hormone analog) in a dose of 0.1 microg/kg to male CBA mice stimulated lymphocyte migration from splenic B zones, caused moderate thinning of the thymic cortex, thickening of the zona fasciculata of the adrenal cortex with signs of corticocyte activation. After administrat...

journal_title：Bulletin of experimental biology and medicine

authors： Bobyntsev II,Dolzhikov AA,Severyanova LA

更新日期：2005-01-01 00:00:00

abstract：:Model experiments on biomicroscopy of mesenteric microvessels in laboratory rats were performed to evaluate the effect of natural metabolites (e.g., amino acid glycine) on the microcirculation. The effect of glycine was determined from a change in the diameter of arterioles. Application of glycine (0.1 ml, 1 M) to the...

journal_title：Bulletin of experimental biology and medicine

authors： Podoprigora GI,Nartsissov YR

更新日期：2009-03-01 00:00:00

abstract：:The cell composition of leukocyte infiltrates in the endometrium, myometrium, and vaginal walls was studied in Wistar rats with modeled chronic endomyometritis after administration of IFNγ (0.1 μg/100 g body weight) in different daily regimens (10.00 or 20.00). Morning injections of this cytokine ameliorated inflammat...

journal_title：Bulletin of experimental biology and medicine

authors： Dergacheva TI,Shurlygina AV,Abdalova AM,Klimontov VV,Trufakin VA,Letyagin AY

更新日期：2020-08-01 00:00:00

abstract：:Morphological changes in the thymus of female Wistar rats with experimental mammary gland carcinomas were studied. After adjuvant therapy, the area of the cortical matter and density of parenchymal cells in the thymus decreased, while areas of the medulla, connective tissue, and content of immunoblasts and macrophages...

journal_title：Bulletin of experimental biology and medicine

authors： Kazakov OV,Kabakov AV,Poveshchenko AF,Ishchenko IY,Poveshchenko OV,Strunkin DN,Raiter TV,Michurina SV,Konenkov VI

更新日期：2017-03-01 00:00:00

abstract：:We studied the effect of allopregnanolone on stress-induced anxiety caused by intranasal administration of corticoliberin to male Wistar rats. Active and passive rats were selected by their T-maze behavior and then were tested in elevated plus maze for initial anxiety level. Basing on test results, the animals were di...

journal_title：Bulletin of experimental biology and medicine

authors： Semenova OG,Rakitskaya VV

更新日期：2014-04-01 00:00:00

abstract：:Age-associated changes in the concentrations of glucose, insulin, and DHEAS in peripheral blood plasma of female rhesus macaques were studied in intact animals and in response to a standard dose of glucose and insulin. Basal levels of insulin and glucose increased, insulin sensitivity and glucose tolerance decreased, ...

journal_title：Bulletin of experimental biology and medicine

authors： Goncharova ND,Vengerin AA,Oganyan TE,Lapin BA

更新日期：2004-03-01 00:00:00

abstract：:Prostatotropic activity of (3,5-dimethyl-4-hydroxy)benzyl thiododecane (T-DD) was evaluated on a model of benign prostatic hyperplasia induced in Wistar rats by chronic (2 months) intraperitoneal administration of sulpiride (40 mg/kg). Morphometric analysis of the dorsolateral lobe of the prostate showed that after th...

journal_title：Bulletin of experimental biology and medicine

authors： Nizomov SA,Sorokina IV,Zhukova NA,Tolstikova TG,Semenov DE,Prosenko AE

更新日期：2019-10-01 00:00:00

abstract：:We studied the role of ryanodine receptors in the effects of hydrogen sulfide on transmitter release from frog motor nerve ending. Sodium hydrosulfide (300 μM), a donor of hydrogen sulfide, reversibly increased the frequency of miniature endplate current without changes in its amplitude-time parameters. These effects ...

journal_title：Bulletin of experimental biology and medicine

authors： Gerasimova EV,Yakovleva OV,Zefirov AL,Sitdikova GF

更新日期：2013-05-01 00:00:00

abstract：:An integrative systemic model of pharmacological reaction to a phytopreparation was created as a result of conceptual structurization of facts and formalization of causal relations. The use of the new methodological approach to the choice, primary screening, and profound studies of plants for prospective addition ther...

journal_title：Bulletin of experimental biology and medicine

authors： Mitrofanova IY,Yanitskaya AV,Butenko DV

更新日期：2013-09-01 00:00:00

abstract：:A stable preparation of agaricinic acid nanoparticles was obtained. The mean hydrodynamic size of nanoparticles according to photon correlation spectroscopy was 200 nm and zeta potential was -57 mV. Cytotoxic activity of agaricinic acid nanoparticles against human HepG2 hepatoma cells was evaluated. Nanoparticles with...

journal_title：Bulletin of experimental biology and medicine

authors： Gudkova OI,Demchenko AG,Shvets AV,Kuryakov VN,Sedyakina NE,Lyundup AV,Feldman NB,Gromovykh TI,Lutsenko SV

更新日期：2020-08-01 00:00:00

abstract：:Morphofunctional evaluation of the effect of biological dressing with collagen-1 on healing of 3A degree burn wound in outbred and mutant Hr(hr)/Hr(hr)(hairless) mice was carried out by the histological method and optic radioautography. A pronounced stimulatory effect of the dressing on skin regeneration in mice was d...

journal_title：Bulletin of experimental biology and medicine

authors： Kolokolchikova EG,Zhirkova EA,Golovatenko-Abramov PK,Platonov ES,Botcharova VS,Khvatov VB

更新日期：2010-07-01 00:00:00