Formation of GABAA receptor complexes containing α1 and α5 subunits is paralleling a multiple T-maze learning task in mice.

abstract：:The cerebellum receives sensory signals from spinocerebellar (lower limbs) and dorsal column nuclei (upper limbs) mossy fibers. In the cerebellum, mossy fibers terminate in bands that are topographically aligned with stripes of Purkinje cells. While much is known about the molecular heterogeneity of Purkinje cell stri...

journal_title：Brain structure & function

authors： Gebre SA,Reeber SL,Sillitoe RV

更新日期：2012-04-01 00:00:00

abstract：:Very preterm infants (≤ 31 weeks gestational age) are at high risk for brain injury and delayed development. Applying functional connectivity and graph theory methods to resting state MRI data (fcMRI), we tested the hypothesis that preterm infants would demonstrate alterations in connectivity measures both globally an...

journal_title：Brain structure & function

authors： Gozdas E,Parikh NA,Merhar SL,Tkach JA,He L,Holland SK

更新日期：2018-11-01 00:00:00

abstract：:Selective attention to features of interest facilitates object processing in a cluttered and dynamic environment. Previous research found that distinct networks of regions across cortex are activated depending on the attended feature. These networks typically consist of posterior feature-preferring regions and anterio...

journal_title：Brain structure & function

authors： Mayer KM,Vuong QC

更新日期：2014-11-01 00:00:00

abstract：:Brain pathology in Friedreich ataxia is characterized by progressive degeneration of nervous tissue in the brainstem, cerebellum and cerebellar peduncles. Evidence of cerebral involvement is however equivocal. This brain imaging study investigates cerebello-cerebral white matter connectivity in Friedreich ataxia with ...

journal_title：Brain structure & function

authors： Zalesky A,Akhlaghi H,Corben LA,Bradshaw JL,Delatycki MB,Storey E,Georgiou-Karistianis N,Egan GF

更新日期：2014-05-01 00:00:00

abstract：:Neocortical layer VI is critically involved in thalamocortical activity changes during the sleep/wake cycle. It receives dense projections from thalamic nuclei sensitive to the wake-promoting neuropeptides orexins, and its deepest part, layer VIb, is the only cortical lamina reactive to orexins. This convergence of wa...

journal_title：Brain structure & function

authors： Hay YA,Andjelic S,Badr S,Lambolez B

更新日期：2015-11-01 00:00:00

abstract：:Previous work in the precocious rodent Octodon degus has shown that exposure to early life stress (ELS) (induced by repeated parental separation) results in changes of excitatory, inhibitory and modulatory transmitter systems in prefrontal and limbic regions of the male brain. The aim of this study was to test the hyp...

journal_title：Brain structure & function

authors： Kunzler J,Braun K,Bock J

更新日期：2015-03-01 00:00:00

abstract：:Distribution of bromodeoxyuridine immunoreactive (BrdU-IR) cell nuclei was analyzed at proximal and remote cortical sites in adult Cebus apella monkeys after a programmed surgical lesion placed either in the prefrontal or in the striate cerebral cortex. Increased GFAP-IR and vimentin-IR astrocytes, as well as Isolecti...

journal_title：Brain structure & function

authors： Lanosa XA,Yáñez A,Alzugaray S,Colombo JA

更新日期：2012-04-01 00:00:00

abstract：:Emergence of advanced network analysis techniques utilizing resting-state functional magnetic resonance imaging (R-fMRI) has enabled a more comprehensive understanding of neurological disorders at a whole-brain level. However, inferring brain connectivity from R-fMRI is a challenging task, particularly when the ultima...

journal_title：Brain structure & function

authors： Wee CY,Yap PT,Zhang D,Wang L,Shen D

更新日期：2014-03-01 00:00:00

abstract：:The anatomic gene expression atlas (AGEA) of the adult mouse brain of the Allen Institute for Brain Science is a transcriptome-based atlas of the adult C57Bl/6 J mouse brain, based on the extensive in situ hybridization dataset of the Institute. This spatial mapping of the gene expression levels of mice under baseline...

journal_title：Brain structure & function

authors： Kalafatakis I,Kalafatakis K,Tsimpolis A,Giannakeas N,Tsipouras M,Tzallas A,Karagogeos D

更新日期：2020-09-01 00:00:00

abstract：:The ventral striatum (VS) is of particular interest in the study of neuropsychiatric disorders. In this study, performed on non-human primates, we associated local perturbation with monosynaptic axonal tracer injection into medial, central and lateral VS to characterize anatomo-functional circuits underlying the respe...

journal_title：Brain structure & function

authors： Sgambato-Faure V,Worbe Y,Epinat J,Féger J,Tremblay L

更新日期：2016-01-01 00:00:00

abstract：:Using T 1-weighted MRI at two different magnetic field strengths, the enhanced longitudinal relaxivity due to paramagnetic manganese ions in mouse brain in vivo is shown to reflect reduced intracellular mobility. One day after systemic administration of manganese chloride, increases of the longitudinal relaxation rate...

journal_title：Brain structure & function

authors： Watanabe T,Frahm J,Michaelis T

更新日期：2015-01-01 00:00:00

abstract：:Inputs to apical dendritic tufts have been considered to be crucial for associative learning, attention and similar ''feedback'' interactions and are located in neocortical layer Ia. Excitatory thalamic projections to apical tufts in layer Ia have been well characterized and their role in the cortical circuit has been...

journal_title：Brain structure & function

authors： Ramos-Moreno T,Clascá F

更新日期：2014-09-01 00:00:00

abstract：:The medial prefrontal cortex (mPFC) has been associated with diverse functions including attentional processes, visceromotor activity, decision making, goal directed behavior, and working memory. Using retrograde tracing techniques, we examined, compared, and contrasted afferent projections to the four divisions of th...

journal_title：Brain structure & function

authors： Hoover WB,Vertes RP

更新日期：2007-09-01 00:00:00

abstract：:Early-life sleep deprivation (ESD) is a serious condition with severe metabolic sequelae. The pineal hormone melatonin plays an important role in homeostatic regulation of metabolic function. Considering norepinephrine-mediated Ca(2+) influx and subsequent protein kinase A (PKA) activation is responsible for downstrea...

journal_title：Brain structure & function

authors： Chen LY,Tiong C,Tsai CH,Liao WC,Yang SF,Youn SC,Mai FD,Chang HM

更新日期：2015-03-01 00:00:00

abstract：:Several studies have begun to demonstrate that contextual memories constitute an important mechanism to guide our attention. Although there is general consensus that the hippocampus is involved in the encoding of contextual memories, it is controversial whether this structure can support implicit forms of contextual m...

journal_title：Brain structure & function

authors： Rosero MA,Winkelmann T,Pohlack S,Cavalli J,Nees F,Flor H

更新日期：2019-07-01 00:00:00

abstract：:The fornix is the primary efferent pathway of the hippocampus and plays a central role in memory circuitry. Diffusion tensor imaging has shown changes in the fornix with typical development and aging. Here, the fornix was investigated in 903 healthy young adult participants aged 22-36 years old from the high-spatial r...

journal_title：Brain structure & function

authors： Cahn AJ,Little G,Beaulieu C,Tétreault P

更新日期：2021-01-02 00:00:00

abstract：:Oscillation activities are the feature of neural network and correlated to different physiological states. The theta (θ) oscillation (2-7 Hz) has been reported in the basal ganglia, and the intrinsic resonance properties of individual neurons have provided a basis for this network oscillation. The basal ganglia neuron...

journal_title：Brain structure & function

authors： Xue WN,Wang Y,He SM,Wang XL,Zhu JL,Gao GD

更新日期：2012-04-01 00:00:00

abstract：:Recently, there have been great interests for computer-aided diagnosis of Alzheimer's disease (AD) and its prodromal stage, mild cognitive impairment (MCI). Unlike the previous methods that considered simple low-level features such as gray matter tissue volumes from MRI, and mean signal intensities from PET, in this p...

journal_title：Brain structure & function

authors： Suk HI,Lee SW,Shen D,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2015-03-01 00:00:00

abstract：:The variety of different causal theories together with inconsistencies about the anatomical brain markers emphasize the heterogeneity of developmental dyslexia. Attempts were made to test on a behavioral level the existence of subtypes of dyslexia showing distinguishable cognitive deficits. Importantly, no research wa...

journal_title：Brain structure & function

authors： Jednoróg K,Gawron N,Marchewka A,Heim S,Grabowska A

更新日期：2014-09-01 00:00:00

abstract：:The developing cerebellum is extremely vulnerable to hypoxia which can damage the Purkinje neurons. We hypothesized that this might be mediated by tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) derived from activated microglia as in other brain areas. One-day-old rats were subjected to hypoxia following, w...

journal_title：Brain structure & function

authors： Kaur C,Sivakumar V,Zou Z,Ling EA

更新日期：2014-01-01 00:00:00

abstract：:Network-level analysis based on anatomical, pairwise similarities (e.g., cortical thickness) has been gaining increasing attention recently. However, there has not been a systematic study of the impact of spatial scale and edge definitions on predictive performance, which is necessary to obtain a clear understanding o...

journal_title：Brain structure & function

authors： Raamana PR,Strother SC,Australian Imaging Biomarkers, Lifestyle flagship study of ageing, for The Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2020-11-01 00:00:00

abstract：:The adult dentate gyrus produces new neurons that morphologically and functionally integrate into the hippocampal network. In the adult brain, most excitatory synapses are ensheathed by astrocytic perisynaptic processes that regulate synaptic structure and function. However, these processes are formed during embryonic...

journal_title：Brain structure & function

authors： Krzisch M,Temprana SG,Mongiat LA,Armida J,Schmutz V,Virtanen MA,Kocher-Braissant J,Kraftsik R,Vutskits L,Conzelmann KK,Bergami M,Gage FH,Schinder AF,Toni N

更新日期：2015-07-01 00:00:00

abstract：:Glucose metabolism produces, by oxidative phosphorylation, more than 15 times the amount of energy generated by aerobic glycolysis. Nonetheless, aerobic glycolysis remains a prevalent metabolic pathway in the brain. Here we review evidence suggesting that this pathway contributes essential molecules to the biomass of ...

journal_title：Brain structure & function

authors： Bauernfeind AL,Barks SK,Duka T,Grossman LI,Hof PR,Sherwood CC

更新日期：2014-07-01 00:00:00

abstract：:Rapid behavioral responses to unexpected events in the acoustic environment are critical for survival. Stimulus-specific adaptation (SSA) is the process whereby some auditory neurons respond better to rare stimuli than to repetitive stimuli. Most experiments on SSA have been performed under anesthesia, and it is unkno...

journal_title：Brain structure & function

authors： Duque D,Malmierca MS

更新日期：2015-11-01 00:00:00

abstract：:Identifying cerebral vulnerability in late life is of paramount importance to prevent pathological trajectories of aging before the onset of symptoms. Considerable evidence suggests that impaired antioxidant mechanisms are a fingerprint of aging-related conditions, but there is a lack of human research linking total a...

journal_title：Brain structure & function

authors： Palomar-Bonet M,Atienza M,Cantero JL

更新日期：2020-03-01 00:00:00

abstract：:World-wide methamphetamine (meth) use is increasing at a rapid rate; therefore, it has become increasingly important to understand the synaptic changes and neural mechanisms affected by drug exposure. In rodents, 6-h access to contingent meth results in an escalation of drug intake and impaired cognitive sequelae typi...

journal_title：Brain structure & function

authors： Mishra D,Pena-Bravo JI,Leong KC,Lavin A,Reichel CM

更新日期：2017-07-01 00:00:00

abstract：:Understanding the human brain is the ultimate goal in neuroscience, but this is extremely challenging in part due to the fact that brain tissue obtained from autopsy is practically the only source of normal brain tissue and also since changes at different levels of biological organization (genetic, molecular, biochemi...

journal_title：Brain structure & function

authors： Gonzalez-Riano C,Tapia-González S,García A,Muñoz A,DeFelipe J,Barbas C

更新日期：2017-08-01 00:00:00

abstract：:A recent virtual-lesion study using inhibitory repetitive transcranial magnetic stimulation (rTMS) confirmed the causal behavioral relevance of the precuneus in the evaluation of one's own memory performance (aka mnemonic metacognition). This study's goal is to elucidate how these TMS-induced neuromodulatory effects m...

journal_title：Brain structure & function

authors： Ye Q,Zou F,Dayan M,Lau H,Hu Y,Kwok SC

更新日期：2019-09-01 00:00:00

abstract：:Stress impacts differently in distinct brain regions. However, so far few studies have focused on the differential responses triggered by stressful stimuli on the intrinsic functional heterogeneity of the hippocampal axis. In this study, we assessed the functional and structural alterations caused by exposure to a chr...

journal_title：Brain structure & function

authors： Pinto V,Costa JC,Morgado P,Mota C,Miranda A,Bravo FV,Oliveira TG,Cerqueira JJ,Sousa N

更新日期：2015-03-01 00:00:00

abstract：:Recent advances in diffusion-weighted MRI (dMRI) and tractography have enabled identification of major long-range white matter tracts in the human brain. Yet, our understanding of shorter tracts, such as those within the parietal lobe, remains limited. Over a century ago, a tract connecting the superior and inferior p...

journal_title：Brain structure & function

authors： Uesaki M,Takemura H,Ashida H

更新日期：2018-01-01 00:00:00