Diffusion properties of the fornix assessed by deterministic tractography shows age, sex, volume, cognitive, hemispheric, and twin relationships in young adults from the Human Connectome Project.

abstract：:To establish the link between structure and function of any large area of the neocortex, it is helpful to identify its principles of organisation. One way to establish such principles is to investigate how differences in whole-brain connectivity are structured across the area. Here, we use Laplacian eigenmaps on diffu...

journal_title：Brain structure & function

authors： Blazquez Freches G,Haak KV,Bryant KL,Schurz M,Beckmann CF,Mars RB

更新日期：2020-05-01 00:00:00

abstract：:The striosome (or patch) was first identified with anatomical techniques as neurons organized in a three-dimensional labyrinth inserted in and interdigitating the rest of neostriatum: the matrix. Striosome and matrix rapidly became known as two neuronal compartments expressing different biochemical markers, embryonic ...

journal_title：Brain structure & function

authors： Lopez-Huerta VG,Nakano Y,Bausenwein J,Jaidar O,Lazarus M,Cherassse Y,Garcia-Munoz M,Arbuthnott G

更新日期：2016-04-01 00:00:00

abstract：:Evidence suggests that extracellular matrix molecules of perivascular basal laminae help orchestrate the molecular assemblies at the gliovascular interface. Specifically, laminin and agrin are thought to tether the dystrophin-associated protein (DAP) complex to the astrocytic basal lamina. This complex includes α-synt...

journal_title：Brain structure & function

authors： Hoddevik EH,Rao SB,Zahl S,Boldt HB,Ottersen OP,Amiry-Moghaddam M

更新日期：2020-03-01 00:00:00

abstract：:Diffusion-weighted magnetic resonance spectroscopy of brain metabolites offers unique access to compartment-specific microstructural information on neural tissue. Here, we investigated in detail the diffusion characteristics of the neuronal/axonal markers N-acetylaspartate + N-acetyl aspartyl glutamate (tNAA) in a sma...

journal_title：Brain structure & function

authors： Ronen I,Budde M,Ercan E,Annese J,Techawiboonwong A,Webb A

更新日期：2014-09-01 00:00:00

abstract：:The basal ganglia of the laboratory rat consist of a few core regions that are specifically interconnected by efferents and afferents of the central nervous system. In nearly 800 reports of tract-tracing investigations the connectivity of the basal ganglia is documented. The readout of connectivity data and the collat...

journal_title：Brain structure & function

authors： Schmitt O,Eipert P,Kettlitz R,Leßmann F,Wree A

更新日期：2016-03-01 00:00:00

abstract：:This study investigates the mechanism of action of spadin, a putative fast-acting peptidic antidepressant (AD) and a functional blocker of the K(+) TREK-1 channel, in relation with the medial prefrontal cortex (mPFC)-dorsal raphé (DRN) serotonergic (5-HT) neurons connectivity. Spadin increased 5-HT neuron firing rate ...

journal_title：Brain structure & function

authors： Moha ou Maati H,Bourcier-Lucas C,Veyssiere J,Kanzari A,Heurteaux C,Borsotto M,Haddjeri N,Lucas G

更新日期：2016-01-01 00:00:00

abstract：:Perineuronal nets (PNNs) are aggregates of extracellular matrix molecules surrounding several types of neurons in the adult CNS, which contribute to stabilising neuronal connections. Interestingly, a reduction of PNN number and staining intensity has been observed in conditions associated with plasticity in the adult ...

journal_title：Brain structure & function

authors： Faralli A,Dagna F,Albera A,Bekku Y,Oohashi T,Albera R,Rossi F,Carulli D

更新日期：2016-07-01 00:00:00

abstract：:The hypoglossal motor nucleus is one of the efferent components of the neural network underlying the tongue prehension behavior of Ranid frogs. Although the appropriate pattern of the motor activity is determined by motor pattern generators, sensory inputs can modify the ongoing motor execution. Combination of fluores...

journal_title：Brain structure & function

authors： Kecskes S,Matesz C,Gaál B,Birinyi A

更新日期：2016-04-01 00:00:00

abstract：:The architecture of the neocortex classically consists of six layers, based on cytological criteria and on the layout of intra/interlaminar connections. Yet, the comparison of cortical cytoarchitectonic features across different species proves overwhelmingly difficult, due to the lack of a reliable model to analyze th...

journal_title：Brain structure & function

authors： Cozzi B,De Giorgio A,Peruffo A,Montelli S,Panin M,Bombardi C,Grandis A,Pirone A,Zambenedetti P,Corain L,Granato A

更新日期：2017-08-01 00:00:00

abstract：:An account of work performed at the UNA laboratories since 1992 on the detection and description of interlaminar glial processes, is presented. The incidental observation (serendipity) of longer than expected glial processes in the superficial layers of the cerebral cortex in hemiparkinsonian Cebus apella monkeys, was...

journal_title：Brain structure & function

authors： Colombo JA

更新日期：2017-04-01 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease of motor neurons (MNs). The molecular pathogenesis of ALS is not understood, thus effective therapies for this disease are lacking. Some forms of ALS are inherited by mutations in the superoxide dismutase-1 (SOD1) gene. Transgenic mice expressing...

journal_title：Brain structure & function

authors： Chen K,Northington FJ,Martin LJ

更新日期：2010-03-01 00:00:00

abstract：:The inner ear is a morphologically complex sensory structure with auditory and vestibular functions. The developing otic epithelium gives rise to neurosensory and non-sensory elements of the adult membranous labyrinth. Extrinsic and intrinsic signals manage the patterning and cell specification of the developing otic ...

journal_title：Brain structure & function

authors： Olaya-Sánchez D,Sánchez-Guardado LÓ,Ohta S,Chapman SC,Schoenwolf GC,Puelles L,Hidalgo-Sánchez M

更新日期：2017-01-01 00:00:00

abstract：:Serotonin neurons arise from the brainstem raphe nuclei and send their projections throughout the brain to release 5-HT which acts as a modulator of several neuronal populations. Previous electron microscopy studies in rats have morphologically determined the distribution of 5-HT release sites (boutons) in certain bra...

journal_title：Brain structure & function

authors： Belmer A,Klenowski PM,Patkar OL,Bartlett SE

更新日期：2017-04-01 00:00:00

abstract：:Adult hippocampal neural stem cells (NSC) are an intriguing source for cell replacement or could serve as delivery vehicles for therapeutic genes. We recently reported selective transduction of adult mouse NSC in the DG by in vivo injection of GFP encoding adenoviral (Ad) vectors engineered to bind NSC-specific peptid...

journal_title：Brain structure & function

authors： Hildebrandt S,Schmidt A,Stoll A,Schmitt O,Köhling R,Wree A,Haas SJ,Pützer BM

更新日期：2010-08-01 00:00:00

abstract：:The transcription factor Pax6 has been reported to specify neural progenitor cell fates during development and maintain neuronal commitments in the adult. The spatiotemporal patterns of Pax6 expression were examined in sagittal and horizontal sections of the embryonic, postnatal, and adult brains using immunohistochem...

journal_title：Brain structure & function

authors： Duan D,Fu Y,Paxinos G,Watson C

更新日期：2013-03-01 00:00:00

abstract：:Dopaminergic neuromodulation is critically important for brain and cognitive integrity. The DRD2/ANKK1 Taq1A polymorphism is associated with striatal dopamine (DA) D2 receptor availability. Some previous studies have found that the A allele of the Taq1A polymorphism influences brain structure, but the results are inco...

journal_title：Brain structure & function

authors： Li X,Papenberg G,Kalpouzos G,Bäckman L,Persson J

更新日期：2018-07-01 00:00:00

abstract：:Detailed information about the excitatory and inhibitory synapses on the hypoglossal motoneurons may help understand the neural mechanism for control of the hypoglossal motoneuron excitability and hence the precise and coordinated movements of the tongue during chewing, swallowing and licking. For this, we investigate...

journal_title：Brain structure & function

authors： Paik SK,Yoo HI,Choi SK,Bae JY,Park SK,Bae YC

更新日期：2019-06-01 00:00:00

abstract：:Recently, there have been great interests for computer-aided diagnosis of Alzheimer's disease (AD) and its prodromal stage, mild cognitive impairment (MCI). Unlike the previous methods that considered simple low-level features such as gray matter tissue volumes from MRI, and mean signal intensities from PET, in this p...

journal_title：Brain structure & function

authors： Suk HI,Lee SW,Shen D,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2015-03-01 00:00:00

abstract：:Functional connectivity (FC) reflects the coherence of spontaneous, low-frequency fluctuations in functional magnetic resonance imaging (fMRI) data. We report a behavior-based connectivity analysis method, in which whole-brain data are used to identify behaviorally relevant, intrinsic FC networks. Nineteen younger adu...

journal_title：Brain structure & function

authors： Chen NK,Chou YH,Song AW,Madden DJ

更新日期：2009-10-01 00:00:00

abstract：:The neural underpinnings of human emotional expression are thought to be unevenly distributed among the two brain hemispheres. However, little is known on the anatomy supporting this claim, particularly in the cerebral white matter. Here, we explored the relationship between hemi-face dominance in emotional expression...

journal_title：Brain structure & function

authors： Ioannucci S,George N,Friedrich P,Cerliani L,Thiebaut de Schotten M

更新日期：2020-05-01 00:00:00

abstract：:One of the major challenges of functional magnetic resonance imaging (fMRI) data analysis is to develop simple and reliable methods to correlate brain regions with functionality. In this paper, we employ a detrending-based fractal method, called detrended fluctuation analysis (DFA), to identify brain activity from fMR...

journal_title：Brain structure & function

authors： Hu J,Lee JM,Gao J,White KD,Crosson B

更新日期：2008-02-01 00:00:00

abstract：:Very preterm infants (≤ 31 weeks gestational age) are at high risk for brain injury and delayed development. Applying functional connectivity and graph theory methods to resting state MRI data (fcMRI), we tested the hypothesis that preterm infants would demonstrate alterations in connectivity measures both globally an...

journal_title：Brain structure & function

authors： Gozdas E,Parikh NA,Merhar SL,Tkach JA,He L,Holland SK

更新日期：2018-11-01 00:00:00

abstract：:We analyzed the developmental history of the subplate and related cellular compartments of the prenatal and early postnatal human cerebrum by combining postmortem histological analysis with in vivo MRI. Histological analysis was performed on 21 postmortem brains (age range: 26 postconceptional weeks to 6.5 years) usin...

journal_title：Brain structure & function

authors： Kostović I,Jovanov-Milošević N,Radoš M,Sedmak G,Benjak V,Kostović-Srzentić M,Vasung L,Čuljat M,Radoš M,Hüppi P,Judaš M

更新日期：2014-01-01 00:00:00

abstract：:The mesocorticolimbic system contains dopamine (DA)-producing neurons in the ventral tegmental area (VTA) and their projection targets, including the medial prefrontal cortex (mPFC), amygdala (AMY) and nucleus accumbens (NAc). Disruption of this system might attribute to mental illnesses. In the present study, we adop...

journal_title：Brain structure & function

authors： Wang YC,Ho UC,Ko MC,Liao CC,Lee LJ

更新日期：2012-04-01 00:00:00

abstract：:Several studies have begun to demonstrate that contextual memories constitute an important mechanism to guide our attention. Although there is general consensus that the hippocampus is involved in the encoding of contextual memories, it is controversial whether this structure can support implicit forms of contextual m...

journal_title：Brain structure & function

authors： Rosero MA,Winkelmann T,Pohlack S,Cavalli J,Nees F,Flor H

更新日期：2019-07-01 00:00:00

abstract：:Patients with Parkinson's disease have difficulties with self-initiating a task and maintaining a steady task performance. We hypothesized that these difficulties relate to reorganization in the sensorimotor execution, cingulo-opercular task-set maintenance, and frontoparietal adaptive control networks. We tested this...

journal_title：Brain structure & function

authors： Tinaz S,Lauro P,Hallett M,Horovitz SG

更新日期：2016-04-01 00:00:00

abstract：:Neuronatomical and pharmacological studies have established GABA-mediated inhibition of the HPA axis at the level of the PVN. The origin of this innervation is a series of local hypothalamic and adjacent forebrain regions that project to stress-integrative hypophysiotropic CRH neurons. While a role in tonic inhibition...

journal_title：Brain structure & function

authors： Cullinan WE,Ziegler DR,Herman JP

更新日期：2008-09-01 00:00:00

abstract：:The frontal cortico-basal ganglia network plays a central role in action selection, associative learning, and motivation, processes requiring the integration of information from functionally distinct cortical regions. The cortico-striatal projection is a likely substrate of information integration, as terminal fields ...

journal_title：Brain structure & function

authors： Heilbronner SR,Meyer MAA,Choi EY,Haber SN

更新日期：2018-07-01 00:00:00

abstract：:Three populations of neurons expressing the vesicular glutamate transporter 2 (Vglut2) were recently described in the A10 area of the mouse midbrain, of which two populations were shown to express the gene encoding, the rate-limiting enzyme for catecholamine synthesis, tyrosine hydroxylase (TH).One of these population...

journal_title：Brain structure & function

authors： Nordenankar K,Smith-Anttila CJ,Schweizer N,Viereckel T,Birgner C,Mejia-Toiber J,Morales M,Leao RN,Wallén-Mackenzie Å

更新日期：2015-07-01 00:00:00

abstract：:The telencephalic subpallium is the source of various GABAergic interneuron cohorts that invade the pallium via tangential migration. Based on genoarchitectonic studies, the subpallium has been subdivided into four major domains: striatum, pallidum, diagonal area and preoptic area (Puelles et al. 2013; Allen Developin...

journal_title：Brain structure & function

authors： Puelles L,Morales-Delgado N,Merchán P,Castro-Robles B,Martínez-de-la-Torre M,Díaz C,Ferran JL

更新日期：2016-07-01 00:00:00