Microglia-derived proinflammatory cytokines tumor necrosis factor-alpha and interleukin-1beta induce Purkinje neuronal apoptosis via their receptors in hypoxic neonatal rat brain.

abstract：:The dorsal part of the developing telencephalon is one of the brain areas that has suffered most drastic changes throughout vertebrate evolution. Its evolutionary increase in complexity was thought to be partly achieved by the appearance of a new neurogenic niche in the embryonic subventricular zone (SVZ). Here, a new...

journal_title：Brain structure & function

authors： Docampo-Seara A,Lagadec R,Mazan S,Rodríguez MA,Quintana-Urzainqui I,Candal E

更新日期：2018-11-01 00:00:00

abstract：:Although several novel approaches for hippocampal subregion delineation have been developed, they need to be applied prospectively and may be limited by long scan times, the use of high field (>3T) imaging systems, and limited reliability metrics. Moreover, the majority of MR imaging data collected to date has employe...

journal_title：Brain structure & function

authors： Rhindress K,Ikuta T,Wellington R,Malhotra AK,Szeszko PR

更新日期：2015-11-01 00:00:00

abstract：:Normally, we are aware that our arms and legs belong to us and not to someone else. However, some stroke patients with hemiparesis/-plegia after right-sided stroke show a disturbed sensation of limb ownership and a disturbed self-awareness of actions and such patients with anosognosia for hemiparesis/plegia typically ...

journal_title：Brain structure & function

authors： Karnath HO,Baier B

更新日期：2010-06-01 00:00:00

abstract：:Selective attention to features of interest facilitates object processing in a cluttered and dynamic environment. Previous research found that distinct networks of regions across cortex are activated depending on the attended feature. These networks typically consist of posterior feature-preferring regions and anterio...

journal_title：Brain structure & function

authors： Mayer KM,Vuong QC

更新日期：2014-11-01 00:00:00

abstract：:The frontal pole corresponds to Brodmann area (BA) 10, the largest single architectonic area in the human frontal lobe. Generally, BA10 is thought to contain two or three subregions that subserve broad functions such as multitasking, social cognition, attention, and episodic memory. However, there is a substantial deb...

journal_title：Brain structure & function

authors： Moayedi M,Salomons TV,Dunlop KA,Downar J,Davis KD

更新日期：2015-09-01 00:00:00

abstract：:The hippocampal formation is important for higher brain functions such as spatial navigation and the consolidation of memory, and it contributes to abilities thought to be uniquely human, yet little is known about how the human hippocampal formation compares to that of our closest living relatives, the chimpanzees. To...

journal_title：Brain structure & function

authors： Rogers Flattery CN,Rosen RF,Farberg AS,Dooyema JM,Hof PR,Sherwood CC,Walker LC,Preuss TM

更新日期：2020-11-01 00:00:00

abstract：:In recent years, the demonstration that structural changes can occur in the human brain beyond those associated with development, ageing and neuropathology has revealed a new approach to studying the neural basis of behaviour. In this review paper, we focus on structural imaging studies of language that have utilised ...

journal_title：Brain structure & function

authors： Richardson FM,Price CJ

更新日期：2009-10-01 00:00:00

abstract：:Neuroimaging studies have demonstrated that mental imagery and perception share similar neural substrates, however, there are still ambiguities according to different auditory imagery content. In addition, there is still a lack of information regarding the underlying neural correlation between the two modalities. In t...

journal_title：Brain structure & function

authors： Gu J,Zhang H,Liu B,Li X,Wang P,Wang B

更新日期：2019-11-01 00:00:00

abstract：:It is well established that environmental influences play a key role in sculpting neuronal connectivity in the brain. One example is the olfactory sensory map of topographic axonal connectivity. While intrinsic odorant receptor signaling in olfactory sensory neurons (OSN) determines anterior-posterior counter gradient...

journal_title：Brain structure & function

authors： Login H,Butowt R,Bohm S

更新日期：2015-07-01 00:00:00

abstract：:The adult dentate gyrus produces new neurons that morphologically and functionally integrate into the hippocampal network. In the adult brain, most excitatory synapses are ensheathed by astrocytic perisynaptic processes that regulate synaptic structure and function. However, these processes are formed during embryonic...

journal_title：Brain structure & function

authors： Krzisch M,Temprana SG,Mongiat LA,Armida J,Schmutz V,Virtanen MA,Kocher-Braissant J,Kraftsik R,Vutskits L,Conzelmann KK,Bergami M,Gage FH,Schinder AF,Toni N

更新日期：2015-07-01 00:00:00

abstract：:The vestibulo-ocular reflex (VOR) adaptation is an ideal model for investigating how the neurosteroid 17 beta-estradiol (E2) contributes to the modification of behavior by regulating synaptic activities. We hypothesized that E2 impacts VOR adaptation by affecting cerebellar synaptic plasticity at the parallel fiber-Pu...

journal_title：Brain structure & function

authors： Dieni CV,Ferraresi A,Sullivan JA,Grassi S,Pettorossi VE,Panichi R

更新日期：2018-03-01 00:00:00

abstract：:Exercise (physical activity) has been proposed as a treatment for drug addiction. In rodents, voluntary wheel running reduces cocaine and nicotine seeking during extinction, and reinstatement of cocaine seeking triggered by drug-cues. The purpose of this study was to examine the effects of chronic wheel running during...

journal_title：Brain structure & function

authors： Sobieraj JC,Kim A,Fannon MJ,Mandyam CD

更新日期：2016-01-01 00:00:00

abstract：:Distribution of bromodeoxyuridine immunoreactive (BrdU-IR) cell nuclei was analyzed at proximal and remote cortical sites in adult Cebus apella monkeys after a programmed surgical lesion placed either in the prefrontal or in the striate cerebral cortex. Increased GFAP-IR and vimentin-IR astrocytes, as well as Isolecti...

journal_title：Brain structure & function

authors： Lanosa XA,Yáñez A,Alzugaray S,Colombo JA

更新日期：2012-04-01 00:00:00

abstract：:One of the major challenges of functional magnetic resonance imaging (fMRI) data analysis is to develop simple and reliable methods to correlate brain regions with functionality. In this paper, we employ a detrending-based fractal method, called detrended fluctuation analysis (DFA), to identify brain activity from fMR...

journal_title：Brain structure & function

authors： Hu J,Lee JM,Gao J,White KD,Crosson B

更新日期：2008-02-01 00:00:00

abstract：:The ventral striatum (VS) is of particular interest in the study of neuropsychiatric disorders. In this study, performed on non-human primates, we associated local perturbation with monosynaptic axonal tracer injection into medial, central and lateral VS to characterize anatomo-functional circuits underlying the respe...

journal_title：Brain structure & function

authors： Sgambato-Faure V,Worbe Y,Epinat J,Féger J,Tremblay L

更新日期：2016-01-01 00:00:00

abstract：:Hyperpolarization-activated cyclic nucleotide-gated cation (HCN) channels have important functions in controlling neuronal excitability and generating rhythmic oscillatory activity. The role of tetratricopeptide repeat-containing Rab8b-interacting protein (TRIP8b) in regulation of hyperpolarization-activated inward cu...

journal_title：Brain structure & function

authors： Zobeiri M,Chaudhary R,Datunashvili M,Heuermann RJ,Lüttjohann A,Narayanan V,Balfanz S,Meuth P,Chetkovich DM,Pape HC,Baumann A,van Luijtelaar G,Budde T

更新日期：2018-04-01 00:00:00

abstract：:Electrical stimulation of the dorsolateral periaqueductal gray (dlPAG) in rats has been shown to elicit panic-like behaviour and can be a useful as an unconditioned stimulus for modelling anticipatory fear and agoraphobia in a contextual fear conditioning paradigm. In this study, we further analysed our previous data ...

journal_title：Brain structure & function

authors： Tan SZK,Temel Y,Chan AY,Mok ATC,Perucho JAU,Blokland A,Aquili L,Lim WL,Lim LW

更新日期：2020-09-01 00:00:00

abstract：:Similar to memory formation, memory extinction is also a new learning process that requires synaptic plasticity. Actin rearrangement is fundamental for synaptic plasticity, however, whether actin rearrangement in the infralimbic cortex (IL) plays a role in memory extinction, as well as the mechanisms underlying it, re...

journal_title：Brain structure & function

authors： Bi AL,Wang Y,Zhang S,Li BQ,Sun ZP,Bi HS,Chen ZY

更新日期：2015-03-01 00:00:00

abstract：:The inner ear is a morphologically complex sensory structure with auditory and vestibular functions. The developing otic epithelium gives rise to neurosensory and non-sensory elements of the adult membranous labyrinth. Extrinsic and intrinsic signals manage the patterning and cell specification of the developing otic ...

journal_title：Brain structure & function

authors： Olaya-Sánchez D,Sánchez-Guardado LÓ,Ohta S,Chapman SC,Schoenwolf GC,Puelles L,Hidalgo-Sánchez M

更新日期：2017-01-01 00:00:00

abstract：:Finding the neuroanatomical correlates of prematurity is vital to understanding which structures are affected, and to designing efficient prevention and treatment strategies. Converging results reveal that thalamic abnormalities are important indicators of prematurity. However, little is known about the localization o...

journal_title：Brain structure & function

authors： Lao Y,Wang Y,Shi J,Ceschin R,Nelson MD,Panigrahy A,Leporé N

更新日期：2016-01-01 00:00:00

abstract：:This study investigates the mechanism of action of spadin, a putative fast-acting peptidic antidepressant (AD) and a functional blocker of the K(+) TREK-1 channel, in relation with the medial prefrontal cortex (mPFC)-dorsal raphé (DRN) serotonergic (5-HT) neurons connectivity. Spadin increased 5-HT neuron firing rate ...

journal_title：Brain structure & function

authors： Moha ou Maati H,Bourcier-Lucas C,Veyssiere J,Kanzari A,Heurteaux C,Borsotto M,Haddjeri N,Lucas G

更新日期：2016-01-01 00:00:00

abstract：:A loss-of-function polymorphism in the α5 nicotinic acetylcholine receptor (nAChR) subunit gene has been linked to both drug abuse and schizophrenia. The α5 nAChR subunit is strategically positioned in the prefrontal cortex (PFC), where a loss-of-function in this subunit may contribute to cognitive disruptions in both...

journal_title：Brain structure & function

authors： Howe WM,Brooks JL,Tierney PL,Pang J,Rossi A,Young D,Dlugolenski K,Guillmette E,Roy M,Hales K,Kozak R

更新日期：2018-03-01 00:00:00

abstract：:The medial prefrontal cortex (mPFC) has been associated with diverse functions including attentional processes, visceromotor activity, decision making, goal directed behavior, and working memory. Using retrograde tracing techniques, we examined, compared, and contrasted afferent projections to the four divisions of th...

journal_title：Brain structure & function

authors： Hoover WB,Vertes RP

更新日期：2007-09-01 00:00:00

abstract：:The basal ganglia of the laboratory rat consist of a few core regions that are specifically interconnected by efferents and afferents of the central nervous system. In nearly 800 reports of tract-tracing investigations the connectivity of the basal ganglia is documented. The readout of connectivity data and the collat...

journal_title：Brain structure & function

authors： Schmitt O,Eipert P,Kettlitz R,Leßmann F,Wree A

更新日期：2016-03-01 00:00:00

abstract：:Retinoic acid, the active form of the nutrient vitamin A, regulates several facets of neuronal plasticity in the hippocampus, including neurogenesis and synaptic strength, acting via specific retinoic acid receptors (RARs). Essential for conversion of vitamin A to retinoic acid is the enzyme retinaldehyde dehydrogenas...

journal_title：Brain structure & function

authors： Fragoso YD,Shearer KD,Sementilli A,de Carvalho LV,McCaffery PJ

更新日期：2012-04-01 00:00:00

abstract：:Olfaction is one of the major sensory modalities that regulates food consumption and is in turn regulated by the feeding state. Given that the olfactory bulb has been shown to be a metabolic sensor, we explored whether the anterior piriform cortex (aPCtx)-a higher olfactory cortical processing area-had the same capaci...

journal_title：Brain structure & function

authors： Al Koborssy D,Palouzier-Paulignan B,Canova V,Thevenet M,Fadool DA,Julliard AK

更新日期：2019-01-01 00:00:00

abstract：:The human visual system is capable of processing visual information from fovea to the far peripheral visual field. Recent fMRI studies have shown a full and detailed retinotopic map in area prostriata, located ventro-dorsally and anterior to the calcarine sulcus along the parieto-occipital sulcus with strong preferenc...

journal_title：Brain structure & function

authors： Kurzawski JW,Mikellidou K,Morrone MC,Pestilli F

更新日期：2020-07-01 00:00:00

abstract：:Recent views of information processing in the (human) brain emphasize the hierarchical structure of the central nervous system, which is assumed to form the basis of a functional hierarchy. Hierarchical predictive processing refers to the notion that higher levels try to predict activity in lower areas, while lower le...

journal_title：Brain structure & function

authors： Kellermann T,Scholle R,Schneider F,Habel U

更新日期：2017-03-01 00:00:00

abstract：:Proprioceptive signals from body muscles have historically been considered to project to the rostrodorsal shell of the ventrobasal thalamic complex [the ventral posterolateral nucleus (VPL) and ventral posteromedial nucleus (VPM)]. However, we have recently found that proprioception from rat jaw-closing muscle spindle...

journal_title：Brain structure & function

authors： Uemura Y,Haque T,Sato F,Tsutsumi Y,Ohara H,Oka A,Furuta T,Bae YC,Yamashiro T,Tachibana Y,Yoshida A

更新日期：2020-09-01 00:00:00

abstract：:The anorexigenic neuropeptide NEFA/nucleobindin 2 (NUCB2)/nesfatin-1-containing neurons are distributed in the brain regions involved in feeding regulation, including the hypothalamic paraventricular nucleus (PVN). Functionally, NUCB2/nesfatin-1 neurons in the PVN regulate feeding through the hypothalamus and brain st...

journal_title：Brain structure & function

authors： Maejima Y,Kumamoto K,Takenoshita S,Shimomura K

更新日期：2016-12-01 00:00:00