Differential impact of chronic stress along the hippocampal dorsal-ventral axis.

abstract：:Evidence suggests that extracellular matrix molecules of perivascular basal laminae help orchestrate the molecular assemblies at the gliovascular interface. Specifically, laminin and agrin are thought to tether the dystrophin-associated protein (DAP) complex to the astrocytic basal lamina. This complex includes α-synt...

journal_title：Brain structure & function

authors： Hoddevik EH,Rao SB,Zahl S,Boldt HB,Ottersen OP,Amiry-Moghaddam M

更新日期：2020-03-01 00:00:00

abstract：:Dopaminergic (DA) inputs to the basolateral nuclear complex of the amygdala (BLC) are critical for several important functions, including reward-related learning, drug-stimulus learning, and fear conditioning. Despite the importance of the DA projection to the BLC, very little is known about which neuronal subpopulati...

journal_title：Brain structure & function

authors： Muller JF,Mascagni F,McDonald AJ

更新日期：2009-02-01 00:00:00

abstract：:Interaction between the hippocampus and the medial prefrontal cortex (mPFC) has been identified as a key target in several neuropsychiatric disorders. However, the hippocampus-mPFC (H-PFC) pathway has not been outlined in mice, which are increasingly the leading choice for new animal models for neurological disorders....

journal_title：Brain structure & function

authors： Tripathi A,Schenker E,Spedding M,Jay TM

更新日期：2016-05-01 00:00:00

abstract：:Melatonin, through its different receptors, has pleiotropic functions in mammalian brain. Melatonin is secreted mainly by the pineal gland and exerts its effects via receptor-mediated and non-receptor-mediated actions. With recent advancement in neuroanatomical mapping, we may now understand better the localizations o...

journal_title：Brain structure & function

authors： Ng KY,Leong MK,Liang H,Paxinos G

更新日期：2017-09-01 00:00:00

abstract：:Inputs to apical dendritic tufts have been considered to be crucial for associative learning, attention and similar ''feedback'' interactions and are located in neocortical layer Ia. Excitatory thalamic projections to apical tufts in layer Ia have been well characterized and their role in the cortical circuit has been...

journal_title：Brain structure & function

authors： Ramos-Moreno T,Clascá F

更新日期：2014-09-01 00:00:00

abstract：:Projections from the prefrontal cortex (PFC) to the amygdala (AMG) regulate affective behaviors in a manner that is modulated by dopamine (DA). Although PFC and DA inputs overlap within the basolateral nucleus (BLA) and intercalated cell masses (ICMs), the spatial relationship between these afferents has not been inve...

journal_title：Brain structure & function

authors： Pinto A,Sesack SR

更新日期：2008-09-01 00:00:00

abstract：:The ventral striatum (VS) is of particular interest in the study of neuropsychiatric disorders. In this study, performed on non-human primates, we associated local perturbation with monosynaptic axonal tracer injection into medial, central and lateral VS to characterize anatomo-functional circuits underlying the respe...

journal_title：Brain structure & function

authors： Sgambato-Faure V,Worbe Y,Epinat J,Féger J,Tremblay L

更新日期：2016-01-01 00:00:00

abstract：:The organization of the serotonergic system, one of the most important neurotransmitter systems in the brain, has been carefully analyzed in most vertebrate groups, and major shared characteristics have been described, although traits particular to each vertebrate class have also been found. The present study is the f...

journal_title：Brain structure & function

authors： López JM,González A

更新日期：2015-01-01 00:00:00

abstract：:The anatomic gene expression atlas (AGEA) of the adult mouse brain of the Allen Institute for Brain Science is a transcriptome-based atlas of the adult C57Bl/6 J mouse brain, based on the extensive in situ hybridization dataset of the Institute. This spatial mapping of the gene expression levels of mice under baseline...

journal_title：Brain structure & function

authors： Kalafatakis I,Kalafatakis K,Tsimpolis A,Giannakeas N,Tsipouras M,Tzallas A,Karagogeos D

更新日期：2020-09-01 00:00:00

abstract：:Rho-associated protein kinases (ROCK) 1 and 2 are attractive drug targets for a range of neurologic disorders; however, a critical barrier to ROCK-based therapeutics is ambiguity over whether there are isoform-specific roles for ROCKs in neuronal structural plasticity. Here, we used a genetics approach to address this...

journal_title：Brain structure & function

authors： Greathouse KM,Boros BD,Deslauriers JF,Henderson BW,Curtis KA,Gentry EG,Herskowitz JH

更新日期：2018-12-01 00:00:00

abstract：:Accumulating evidence suggests that besides its function in early facial feature processing, the role of the right occipital face area (rOFA) extends to higher level, image-independent processing. Recent studies hint at the possibility that the activity of this region can be modulated by semantic information as well. ...

journal_title：Brain structure & function

authors： Ambrus GG,Amado C,Krohn L,Kovács G

更新日期：2019-01-01 00:00:00

abstract：:Understanding the human brain is the ultimate goal in neuroscience, but this is extremely challenging in part due to the fact that brain tissue obtained from autopsy is practically the only source of normal brain tissue and also since changes at different levels of biological organization (genetic, molecular, biochemi...

journal_title：Brain structure & function

authors： Gonzalez-Riano C,Tapia-González S,García A,Muñoz A,DeFelipe J,Barbas C

更新日期：2017-08-01 00:00:00

abstract：:Growing evidence indicates that physical exercise increases hippocampal volume. This has consistently been shown in mice and men using magnetic resonance imaging. On the other hand, histological studies have reported profound alterations on a cellular level including increased adult hippocampal neurogenesis after exer...

journal_title：Brain structure & function

authors： Biedermann SV,Fuss J,Steinle J,Auer MK,Dormann C,Falfán-Melgoza C,Ende G,Gass P,Weber-Fahr W

更新日期：2016-04-01 00:00:00

abstract：:We investigated whether pre-operative MRI measures of focal brain atrophy could predict cognitive decline occurring after deep brain stimulation (DBS) of the subthalamic nucleus (STN) in patients with Parkinson's disease (PD). For that purpose, we prospectively collected data of 42 consecutive patients with PD who und...

journal_title：Brain structure & function

authors： Planche V,Munsch F,Pereira B,de Schlichting E,Vidal T,Coste J,Morand D,de Chazeron I,Derost P,Debilly B,Llorca PM,Lemaire JJ,Marques A,Durif F

更新日期：2018-09-01 00:00:00

abstract：:Recent studies of the neurobiology of the dorsal frontal cortex (FC) of the ferret have illuminated its key role in the attention network, top-down cognitive control of sensory processing, and goal directed behavior. To elucidate the neuroanatomical regions of the dorsal FC, and delineate the boundary between premotor...

journal_title：Brain structure & function

authors： Radtke-Schuller S,Town SM,Yin P,Elgueda D,Schuller G,Bizley JK,Shamma SA,Fritz JB

更新日期：2020-06-01 00:00:00

abstract：:The paraventricular nucleus of the thalamus (PVT) is part of a group of midline and intralaminar thalamic nuclei implicated in arousal and attention. Recent research points to anatomical and functional differences between the anterior (aPVT) and posterior PVT (pPVT). The present study re-examines the main sources of b...

journal_title：Brain structure & function

authors： Li S,Kirouac GJ

更新日期：2012-04-01 00:00:00

abstract：:A loss-of-function polymorphism in the α5 nicotinic acetylcholine receptor (nAChR) subunit gene has been linked to both drug abuse and schizophrenia. The α5 nAChR subunit is strategically positioned in the prefrontal cortex (PFC), where a loss-of-function in this subunit may contribute to cognitive disruptions in both...

journal_title：Brain structure & function

authors： Howe WM,Brooks JL,Tierney PL,Pang J,Rossi A,Young D,Dlugolenski K,Guillmette E,Roy M,Hales K,Kozak R

更新日期：2018-03-01 00:00:00

abstract：:The fornix is the primary efferent pathway of the hippocampus and plays a central role in memory circuitry. Diffusion tensor imaging has shown changes in the fornix with typical development and aging. Here, the fornix was investigated in 903 healthy young adult participants aged 22-36 years old from the high-spatial r...

journal_title：Brain structure & function

authors： Cahn AJ,Little G,Beaulieu C,Tétreault P

更新日期：2021-01-02 00:00:00

abstract：:The cerebellum receives sensory signals from spinocerebellar (lower limbs) and dorsal column nuclei (upper limbs) mossy fibers. In the cerebellum, mossy fibers terminate in bands that are topographically aligned with stripes of Purkinje cells. While much is known about the molecular heterogeneity of Purkinje cell stri...

journal_title：Brain structure & function

authors： Gebre SA,Reeber SL,Sillitoe RV

更新日期：2012-04-01 00:00:00

abstract：:Substance used during adolescent period increases the risk of psychiatric disorders in later life, but the underlying neural mechanisms remain unclear. We hypothesize that synaptic remodeling and changes of homeostasis in the medial prefrontal cortex (mPFC) following adolescent cocaine exposure may last for a long tim...

journal_title：Brain structure & function

authors： Zhu W,Ge X,Gao P,Li M,Guan Y,Guan X

更新日期：2018-05-01 00:00:00

abstract：:Glycoproteins are complex molecules of the cell surface and the extracellular matrix (ECM) playing a fundamental role in the migration, guidance and synapse formation of neurons. In the present study, the glycosylated protein composition and localization were investigated in the adult and developing CNS of an aquatic ...

journal_title：Brain structure & function

authors： Serfozo Z,Elekes K

更新日期：2009-12-01 00:00:00

abstract：:Chaining or cascading of different actions and responses is necessary to accomplish a goal. Yet, little is known about the functional neuroanatomical-electrophysiological mechanisms mediating these processes. Computational models suggest that medium spiny neurons (MSNs) play an important role in action cascading, but ...

journal_title：Brain structure & function

authors： Beste C,Saft C

更新日期：2015-01-01 00:00:00

abstract：:Recently, neuroimaging-based Alzheimer's disease (AD) or mild cognitive impairment (MCI) diagnosis has attracted researchers in the field, due to the increasing prevalence of the diseases. Unfortunately, the unfavorable high-dimensional nature of neuroimaging data, but a limited small number of samples available, make...

journal_title：Brain structure & function

authors： Suk HI,Lee SW,Shen D,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2016-06-01 00:00:00

abstract：:Serum response factor (SRF) is a major transcription factor that regulates the expression of several plasticity-associated genes in the brain. Although the developmental expression of SRF in excitatory neurons is crucial for establishing proper hippocampal circuitry, no substantial evidence of its role in unstimulated...

journal_title：Brain structure & function

authors： Nader K,Krysiak A,Beroun A,Pekala M,Szymanska M,Kuzniewska B,Radwanska K,Kaczmarek L,Kalita K

更新日期：2019-11-01 00:00:00

abstract：:Brain connectivity in non-human primates (NHPs) has been mainly investigated using tracer techniques and functional connectivity studies. Data on structural connections are scarce and come from diffusion tensor imaging (DTI), since gross anatomical white matter dissection studies in the NHP are lacking. The current st...

journal_title：Brain structure & function

authors： Decramer T,Swinnen S,van Loon J,Janssen P,Theys T

更新日期：2018-11-01 00:00:00

abstract：:Von Economo's neurons (VENs) are large, bipolar or corkscrew-shaped neurons located in layers III and V of the frontoinsular and the anterior cingulate cortices. VENs are reported to be altered in pathologies such as frontotemporal dementia and autism, in which the individual's self control is seriously compromised. T...

journal_title：Brain structure & function

authors： Cauda F,Torta DM,Sacco K,D'Agata F,Geda E,Duca S,Geminiani G,Vercelli A

更新日期：2013-01-01 00:00:00

abstract：:In the neocortex, large layer 5B pyramidal neurons implement a high-density firing code. In contrast, other subtypes of pyramidal neurons, including those in layer 2/3, are functionally characterized by their sparse firing rate. Here, we investigate the synaptic basis of this behavior by comparing the properties of th...

journal_title：Brain structure & function

authors： Sempere-Ferràndez A,Martínez S,Geijo-Barrientos E

更新日期：2019-05-01 00:00:00

abstract：:Achievement motivation can be defined as a recurrent need to improve one's past performance. Despite previous functional imaging studies on motivation-related functional activation, the relationship between regional gray matter (rGM) morphology and achievement motivation has never been investigated. We used voxel-base...

journal_title：Brain structure & function

authors： Takeuchi H,Taki Y,Nouchi R,Sekiguchi A,Kotozaki Y,Miyauchi CM,Yokoyama R,Iizuka K,Hashizume H,Nakagawa S,Kunitoki K,Sassa Y,Kawashima R

更新日期：2014-01-01 00:00:00

abstract：:Prolactin is fundamental for the expression of maternal behaviour. In virgin female rats, prolactin administered upon steroid hormone priming accelerates the onset of maternal care. By contrast, the role of prolactin in mice maternal behaviour remains unclear. This study aims at characterizing central prolactin activi...

journal_title：Brain structure & function

authors： Salais-López H,Lanuza E,Agustín-Pavón C,Martínez-García F

更新日期：2017-03-01 00:00:00

abstract：:The extensive and increasing use of structural neuroimaging in the neurosciences rests on the assumption of an intimate relationship between structure and function in the human brain. However, few studies have examined the relationship between advanced magnetic resonance imaging (MRI) indices of cerebral structure and...

journal_title：Brain structure & function

authors： Elvsåshagen T,Moberget T,Bøen E,Hol PK,Malt UF,Andersson S,Westlye LT

更新日期：2015-03-01 00:00:00