Distinct and complementary functions of rho kinase isoforms ROCK1 and ROCK2 in prefrontal cortex structural plasticity.

abstract：:World-wide methamphetamine (meth) use is increasing at a rapid rate; therefore, it has become increasingly important to understand the synaptic changes and neural mechanisms affected by drug exposure. In rodents, 6-h access to contingent meth results in an escalation of drug intake and impaired cognitive sequelae typi...

journal_title：Brain structure & function

authors： Mishra D,Pena-Bravo JI,Leong KC,Lavin A,Reichel CM

更新日期：2017-07-01 00:00:00

abstract：:In the superior parietal lobule (SPL), the anterior part (area PE) is known to process somatosensory information, while the caudalmost part (areas V6Av and V6) processes visual information. Here we studied the visual and somatosensory properties of the areas PEc and V6Ad located in between the somatosensory and visual...

journal_title：Brain structure & function

authors： Gamberini M,Dal Bò G,Breveglieri R,Briganti S,Passarelli L,Fattori P,Galletti C

更新日期：2018-05-01 00:00:00

abstract：:Distribution of bromodeoxyuridine immunoreactive (BrdU-IR) cell nuclei was analyzed at proximal and remote cortical sites in adult Cebus apella monkeys after a programmed surgical lesion placed either in the prefrontal or in the striate cerebral cortex. Increased GFAP-IR and vimentin-IR astrocytes, as well as Isolecti...

journal_title：Brain structure & function

authors： Lanosa XA,Yáñez A,Alzugaray S,Colombo JA

更新日期：2012-04-01 00:00:00

abstract：:Perineuronal nets (PNNs) are aggregates of extracellular matrix molecules surrounding several types of neurons in the adult CNS, which contribute to stabilising neuronal connections. Interestingly, a reduction of PNN number and staining intensity has been observed in conditions associated with plasticity in the adult ...

journal_title：Brain structure & function

authors： Faralli A,Dagna F,Albera A,Bekku Y,Oohashi T,Albera R,Rossi F,Carulli D

更新日期：2016-07-01 00:00:00

abstract：:Cerebellar volume declines with aging. Few studies have investigated age differences in regional cerebellar volume (RCV) and their association with motor and cognitive function. In 213 healthy older adults, we investigated the association of age with motor skills, cognition and RCV. Subsequently, we studied the associ...

journal_title：Brain structure & function

authors： Koppelmans V,Hoogendam YY,Hirsiger S,Mérillat S,Jäncke L,Seidler RD

更新日期：2017-05-01 00:00:00

abstract：:The primary systems framework has been used to relate behavioural performance across many different language activities to the status of core underpinning domain-general cognitive systems. This study provided the first quantitative investigation of this account at both behavioural and neural levels in a group of patie...

journal_title：Brain structure & function

authors： Woollams AM,Halai A,Lambon Ralph MA

更新日期：2018-11-01 00:00:00

abstract：:The frontal pole corresponds to Brodmann area (BA) 10, the largest single architectonic area in the human frontal lobe. Generally, BA10 is thought to contain two or three subregions that subserve broad functions such as multitasking, social cognition, attention, and episodic memory. However, there is a substantial deb...

journal_title：Brain structure & function

authors： Moayedi M,Salomons TV,Dunlop KA,Downar J,Davis KD

更新日期：2015-09-01 00:00:00

abstract：:Growing evidence indicates that physical exercise increases hippocampal volume. This has consistently been shown in mice and men using magnetic resonance imaging. On the other hand, histological studies have reported profound alterations on a cellular level including increased adult hippocampal neurogenesis after exer...

journal_title：Brain structure & function

authors： Biedermann SV,Fuss J,Steinle J,Auer MK,Dormann C,Falfán-Melgoza C,Ende G,Gass P,Weber-Fahr W

更新日期：2016-04-01 00:00:00

abstract：:Evidence suggests that extracellular matrix molecules of perivascular basal laminae help orchestrate the molecular assemblies at the gliovascular interface. Specifically, laminin and agrin are thought to tether the dystrophin-associated protein (DAP) complex to the astrocytic basal lamina. This complex includes α-synt...

journal_title：Brain structure & function

authors： Hoddevik EH,Rao SB,Zahl S,Boldt HB,Ottersen OP,Amiry-Moghaddam M

更新日期：2020-03-01 00:00:00

abstract：:Von Economo's neurons (VENs) are large, bipolar or corkscrew-shaped neurons located in layers III and V of the frontoinsular and the anterior cingulate cortices. VENs are reported to be altered in pathologies such as frontotemporal dementia and autism, in which the individual's self control is seriously compromised. T...

journal_title：Brain structure & function

authors： Cauda F,Torta DM,Sacco K,D'Agata F,Geda E,Duca S,Geminiani G,Vercelli A

更新日期：2013-01-01 00:00:00

abstract：:In recent years, the demonstration that structural changes can occur in the human brain beyond those associated with development, ageing and neuropathology has revealed a new approach to studying the neural basis of behaviour. In this review paper, we focus on structural imaging studies of language that have utilised ...

journal_title：Brain structure & function

authors： Richardson FM,Price CJ

更新日期：2009-10-01 00:00:00

abstract：:Network-level analysis based on anatomical, pairwise similarities (e.g., cortical thickness) has been gaining increasing attention recently. However, there has not been a systematic study of the impact of spatial scale and edge definitions on predictive performance, which is necessary to obtain a clear understanding o...

journal_title：Brain structure & function

authors： Raamana PR,Strother SC,Australian Imaging Biomarkers, Lifestyle flagship study of ageing, for The Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2020-11-01 00:00:00

abstract：:Sublineage diversification of specific neural cell classes occurs in complex as well as simply organized regions of the central and peripheral nervous systems; the significance of the phenomenon, however, remains insufficiently understood. The unipolar brush cells (UBCs) are glutamatergic cerebellar interneurons that ...

journal_title：Brain structure & function

authors： Sekerková G,Watanabe M,Martina M,Mugnaini E

更新日期：2014-03-01 00:00:00

abstract：:The basal ganglia of the laboratory rat consist of a few core regions that are specifically interconnected by efferents and afferents of the central nervous system. In nearly 800 reports of tract-tracing investigations the connectivity of the basal ganglia is documented. The readout of connectivity data and the collat...

journal_title：Brain structure & function

authors： Schmitt O,Eipert P,Kettlitz R,Leßmann F,Wree A

更新日期：2016-03-01 00:00:00

abstract：:A hierarchical and modular organization is a central hypothesis in the current primate model of auditory cortex (AC) but lacks validation in humans. Here we investigated whether fMRI connectivity at rest and during active tasks is informative of the functional organization of human AC. Identical pitch-varying sounds w...

journal_title：Brain structure & function

authors： Häkkinen S,Rinne T

更新日期：2018-06-01 00:00:00

abstract：:Projections from the prefrontal cortex (PFC) to the amygdala (AMG) regulate affective behaviors in a manner that is modulated by dopamine (DA). Although PFC and DA inputs overlap within the basolateral nucleus (BLA) and intercalated cell masses (ICMs), the spatial relationship between these afferents has not been inve...

journal_title：Brain structure & function

authors： Pinto A,Sesack SR

更新日期：2008-09-01 00:00:00

abstract：:The midline and intralaminar thalamic nuclei (MITN), locus coeruleus (LC) and cingulate cortex contain nociceptive neurons. The MITN that project to cingulate cortex have a prominent innervation by norepinephrinergic axons primarily originating from the LC. The hypothesis explored in this study is that MITN neurons th...

journal_title：Brain structure & function

authors： Vogt BA,Hof PR,Friedman DP,Sikes RW,Vogt LJ

更新日期：2008-08-01 00:00:00

abstract：:Melatonin, through its different receptors, has pleiotropic functions in mammalian brain. Melatonin is secreted mainly by the pineal gland and exerts its effects via receptor-mediated and non-receptor-mediated actions. With recent advancement in neuroanatomical mapping, we may now understand better the localizations o...

journal_title：Brain structure & function

authors： Ng KY,Leong MK,Liang H,Paxinos G

更新日期：2017-09-01 00:00:00

abstract：:Reduction in the amount of brain-derived neurotrophic factor (BDNF) in corticostriatal afferents is thought to contribute to the vulnerability of medium spiny striatal neurons in Huntington's disease. In young Bdnf heterozygous ((+/-)) mice, striatal medium spiny neurons (MSNs) express less preprodynorphin (PPD), prep...

journal_title：Brain structure & function

authors： Saylor AJ,McGinty JF

更新日期：2010-08-01 00:00:00

abstract：:Serotonin neurons arise from the brainstem raphe nuclei and send their projections throughout the brain to release 5-HT which acts as a modulator of several neuronal populations. Previous electron microscopy studies in rats have morphologically determined the distribution of 5-HT release sites (boutons) in certain bra...

journal_title：Brain structure & function

authors： Belmer A,Klenowski PM,Patkar OL,Bartlett SE

更新日期：2017-04-01 00:00:00

abstract：:MRI was employed to follow the neurodegenerative foci and the localization of inflammatory cells by magnetically labeled CD4+ or CD8+ lymphocytes in the ischemia/reperfusion long-lived rats (9 and 13 months after 10 min of cardiac arrest). MRI of ischemic rats showed: (1) blood-brain barrier (BBB) leakage in the area ...

journal_title：Brain structure & function

authors： Sekeljic V,Bataveljic D,Stamenkovic S,Ułamek M,Jabłoński M,Radenovic L,Pluta R,Andjus PR

更新日期：2012-04-01 00:00:00

abstract：:Despite robust sex differences in behavioral responses to drugs of abuse, relatively little is known about structural sex differences in synaptic connectivity of reward circuits such as in the nucleus accumbens (NAc). Previously, we showed that distal dendritic spine density on medium spiny neurons in the NAc is highe...

journal_title：Brain structure & function

authors： Wissman AM,May RM,Woolley CS

更新日期：2012-04-01 00:00:00

abstract：:A rapidly increasing number of studies are quantifying the system-level network architecture of the human brain based on structural-to-structural and functional-to-functional relationships. However, a largely unexplored area is the nature and existence of "cross-modal" structural-functional relationships, in which, fo...

journal_title：Brain structure & function

authors： Harms MP,Wang L,Csernansky JG,Barch DM

更新日期：2013-01-01 00:00:00

abstract：:Almost 30 years ago, the monoclonal antibody Py was developed to detect pyramidal neurons in the CA3 region of the rat hippocampus. The utility of this antibody quickly expanded when several groups discovered that it could be used to identify very specific populations of neurons in the normal, developing, and diseased...

journal_title：Brain structure & function

authors： Fuller HR,Marani L,Holt I,Woodhams PL,Webb MM,Gates MA

更新日期：2017-03-01 00:00:00

abstract：:To better understand information transfer along the hippocampal pathways and its plasticity, here we studied the antidromic responses of the dentate gyrus (DG) and CA3 to activation of the mossy fibers and Schaffer collaterals, respectively, in hippocampal slices from naïve and epileptic rats. We applied trains of 600...

journal_title：Brain structure & function

authors： Franco LM,Beltrán JQ,Tapia JA,Ortiz F,Manjarrez E,Gutiérrez R

更新日期：2016-05-01 00:00:00

abstract：:The medial prefrontal cortex (mPFC) has been associated with diverse functions including attentional processes, visceromotor activity, decision making, goal directed behavior, and working memory. Using retrograde tracing techniques, we examined, compared, and contrasted afferent projections to the four divisions of th...

journal_title：Brain structure & function

authors： Hoover WB,Vertes RP

更新日期：2007-09-01 00:00:00

abstract：:The organization of the pallial derivatives across vertebrates follows a comparable elementary arrangement, although not all of them possess a layered cortical structure as sophisticated as the cerebral cortex of mammals. However, its expansion along evolution has only been possible by the development and coevolution ...

journal_title：Brain structure & function

authors： Jiménez S,López JM,Lozano D,Morona R,González A,Moreno N

更新日期：2020-09-01 00:00:00

abstract：:Optokinetic eye movements are crucial for keeping a stable image on the retina during movements of the head. These eye movements can be differentiated into a cortically generated response (optokinetic look nystagmus) and the highly reflexive optokinetic stare nystagmus, which is controlled by circuits in the brainstem...

journal_title：Brain structure & function

authors： Ruehl RM,Hinkel C,Bauermann T,Eulenburg PZ

更新日期：2017-12-01 00:00:00

abstract：:Neonatal brain lesions cause deficits in structure and function of the cerebral cortex that sometimes are not fully expressed until adolescence. To better understand the onset and persistence of changes caused by postnatal day 7 (P7) ethanol treatment, we examined neocortical cell numbers, volume, surface area and thi...

journal_title：Brain structure & function

authors： Smiley JF,Bleiwas C,Masiello K,Petkova E,Betz J,Hui M,Wilson DA,Saito M

更新日期：2019-06-01 00:00:00

abstract：:Interest in the study of brain connectivity is growing, particularly in understanding the dynamics of the structural/functional connectivity relation. Structural and functional connectivity are most often analysed independently of each other. Track-weighted functional connectivity (TW-FC) was recently proposed as a me...

journal_title：Brain structure & function

authors： Calamante F,Smith RE,Liang X,Zalesky A,Connelly A

更新日期：2017-11-01 00:00:00