Track-weighted dynamic functional connectivity (TW-dFC): a new method to study time-resolved functional connectivity.

abstract：:Individuals with Down syndrome (DS) exhibit intellectual disability and develop Alzheimer's disease-like neuropathology during the third decade of life. The Ts65Dn mouse model of DS exhibits key features of both disorders, including impairments in learning, attention and memory, as well as atrophy of basal forebrain c...

journal_title：Brain structure & function

authors： Powers BE,Velazquez R,Kelley CM,Ash JA,Strawderman MS,Alldred MJ,Ginsberg SD,Mufson EJ,Strupp BJ

更新日期：2016-12-01 00:00:00

abstract：:Substance used during adolescent period increases the risk of psychiatric disorders in later life, but the underlying neural mechanisms remain unclear. We hypothesize that synaptic remodeling and changes of homeostasis in the medial prefrontal cortex (mPFC) following adolescent cocaine exposure may last for a long tim...

journal_title：Brain structure & function

authors： Zhu W,Ge X,Gao P,Li M,Guan Y,Guan X

更新日期：2018-05-01 00:00:00

abstract：:A hierarchical and modular organization is a central hypothesis in the current primate model of auditory cortex (AC) but lacks validation in humans. Here we investigated whether fMRI connectivity at rest and during active tasks is informative of the functional organization of human AC. Identical pitch-varying sounds w...

journal_title：Brain structure & function

authors： Häkkinen S,Rinne T

更新日期：2018-06-01 00:00:00

abstract：:The effect of intracortical microstimulation has been studied in several cortical areas from motor to sensory areas. The frontal pole has received particular attention, and several microstimulation studies have been conducted in the frontal eye field, supplementary eye field, and the premotor ear-eye field, but no mic...

journal_title：Brain structure & function

authors： Lanzilotto M,Perciavalle V,Lucchetti C

更新日期：2015-03-01 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease of motor neurons (MNs). The molecular pathogenesis of ALS is not understood, thus effective therapies for this disease are lacking. Some forms of ALS are inherited by mutations in the superoxide dismutase-1 (SOD1) gene. Transgenic mice expressing...

journal_title：Brain structure & function

authors： Chen K,Northington FJ,Martin LJ

更新日期：2010-03-01 00:00:00

abstract：:Identifying cerebral vulnerability in late life is of paramount importance to prevent pathological trajectories of aging before the onset of symptoms. Considerable evidence suggests that impaired antioxidant mechanisms are a fingerprint of aging-related conditions, but there is a lack of human research linking total a...

journal_title：Brain structure & function

authors： Palomar-Bonet M,Atienza M,Cantero JL

更新日期：2020-03-01 00:00:00

abstract：:Coordinated modulation of sympathetic and parasympathetic nervous activity is required for physiological regulation of tissue function. Anatomically, whilst the peripheral sympathetic and parasympathetic pathways are separate, the distribution of premotor neurons in higher brain regions often overlaps. This co-distrib...

journal_title：Brain structure & function

authors： Hettigoda NS,Fong AY,Badoer E,McKinley MJ,Oldfield BJ,Allen AM

更新日期：2015-07-01 00:00:00

abstract：:The telencephalic subpallium is the source of various GABAergic interneuron cohorts that invade the pallium via tangential migration. Based on genoarchitectonic studies, the subpallium has been subdivided into four major domains: striatum, pallidum, diagonal area and preoptic area (Puelles et al. 2013; Allen Developin...

journal_title：Brain structure & function

authors： Puelles L,Morales-Delgado N,Merchán P,Castro-Robles B,Martínez-de-la-Torre M,Díaz C,Ferran JL

更新日期：2016-07-01 00:00:00

abstract：:The extensive and increasing use of structural neuroimaging in the neurosciences rests on the assumption of an intimate relationship between structure and function in the human brain. However, few studies have examined the relationship between advanced magnetic resonance imaging (MRI) indices of cerebral structure and...

journal_title：Brain structure & function

authors： Elvsåshagen T,Moberget T,Bøen E,Hol PK,Malt UF,Andersson S,Westlye LT

更新日期：2015-03-01 00:00:00

abstract：:The variety of different causal theories together with inconsistencies about the anatomical brain markers emphasize the heterogeneity of developmental dyslexia. Attempts were made to test on a behavioral level the existence of subtypes of dyslexia showing distinguishable cognitive deficits. Importantly, no research wa...

journal_title：Brain structure & function

authors： Jednoróg K,Gawron N,Marchewka A,Heim S,Grabowska A

更新日期：2014-09-01 00:00:00

abstract：:The characterization of neuronal properties is a necessary first step toward understanding how the ventrolateral preoptic nucleus (VLPO) neuronal network regulates slow-wave sleep (SWS). Indeed, the electrophysiological heterogeneity of VLPO neurons suggests the existence of subtypes that could differently contribute ...

journal_title：Brain structure & function

authors： Dubourget R,Sangare A,Geoffroy H,Gallopin T,Rancillac A

更新日期：2017-04-01 00:00:00

abstract：:Multisensory integration does not only recruit higher-level association cortex, but also low-level and even primary sensory cortices. Here, we will describe and quantify two types of anatomical pathways, a thalamocortical and a corticocortical that possibly underlie short-latency multisensory integration processes in ...

journal_title：Brain structure & function

authors： Henschke JU,Noesselt T,Scheich H,Budinger E

更新日期：2015-03-01 00:00:00

abstract：:It is well established that environmental influences play a key role in sculpting neuronal connectivity in the brain. One example is the olfactory sensory map of topographic axonal connectivity. While intrinsic odorant receptor signaling in olfactory sensory neurons (OSN) determines anterior-posterior counter gradient...

journal_title：Brain structure & function

authors： Login H,Butowt R,Bohm S

更新日期：2015-07-01 00:00:00

abstract：:Nitric oxide (NO) is well demonstrated to act as a neuronal messenger in neurotransmission in vertebrate animals. We are for the first time reporting nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d) and neuronal nitric oxide synthase (nNOS) in the Mauthner cells (MC) of the carp, Labeo rohita brain dur...

journal_title：Brain structure & function

authors： Palande NV,Biswas S,Jadhao AG

更新日期：2011-03-01 00:00:00

abstract：:The architecture of the neocortex classically consists of six layers, based on cytological criteria and on the layout of intra/interlaminar connections. Yet, the comparison of cortical cytoarchitectonic features across different species proves overwhelmingly difficult, due to the lack of a reliable model to analyze th...

journal_title：Brain structure & function

authors： Cozzi B,De Giorgio A,Peruffo A,Montelli S,Panin M,Bombardi C,Grandis A,Pirone A,Zambenedetti P,Corain L,Granato A

更新日期：2017-08-01 00:00:00

abstract：:Neuroimaging studies have demonstrated that mental imagery and perception share similar neural substrates, however, there are still ambiguities according to different auditory imagery content. In addition, there is still a lack of information regarding the underlying neural correlation between the two modalities. In t...

journal_title：Brain structure & function

authors： Gu J,Zhang H,Liu B,Li X,Wang P,Wang B

更新日期：2019-11-01 00:00:00

abstract：:The Ly-6 superfamily of proteins, which affects diverse processes in the immune system, has attracted renewed attention due to the ability of some Ly-6 proteins to bind to and modulate the function of neuronal nicotinic acetylcholine receptors (nAChRs). However, there is a scarcity of knowledge regarding the distribut...

journal_title：Brain structure & function

authors： Thomsen MS,Cinar B,Jensen MM,Lyukmanova EN,Shulepko MA,Tsetlin V,Klein AB,Mikkelsen JD

更新日期：2014-11-01 00:00:00

abstract：:This study investigates the mechanism of action of spadin, a putative fast-acting peptidic antidepressant (AD) and a functional blocker of the K(+) TREK-1 channel, in relation with the medial prefrontal cortex (mPFC)-dorsal raphé (DRN) serotonergic (5-HT) neurons connectivity. Spadin increased 5-HT neuron firing rate ...

journal_title：Brain structure & function

authors： Moha ou Maati H,Bourcier-Lucas C,Veyssiere J,Kanzari A,Heurteaux C,Borsotto M,Haddjeri N,Lucas G

更新日期：2016-01-01 00:00:00

abstract：:Rho-associated protein kinases (ROCK) 1 and 2 are attractive drug targets for a range of neurologic disorders; however, a critical barrier to ROCK-based therapeutics is ambiguity over whether there are isoform-specific roles for ROCKs in neuronal structural plasticity. Here, we used a genetics approach to address this...

journal_title：Brain structure & function

authors： Greathouse KM,Boros BD,Deslauriers JF,Henderson BW,Curtis KA,Gentry EG,Herskowitz JH

更新日期：2018-12-01 00:00:00

abstract：:Retinoic acid, the active form of the nutrient vitamin A, regulates several facets of neuronal plasticity in the hippocampus, including neurogenesis and synaptic strength, acting via specific retinoic acid receptors (RARs). Essential for conversion of vitamin A to retinoic acid is the enzyme retinaldehyde dehydrogenas...

journal_title：Brain structure & function

authors： Fragoso YD,Shearer KD,Sementilli A,de Carvalho LV,McCaffery PJ

更新日期：2012-04-01 00:00:00

abstract：:The descending corticospinal (CS) projection has been considered a key element for motor control, which results from direct and indirect modulation of spinal cord pre-motor interneurons in the intermediate gray matter of the spinal cord, which, in turn, influences motoneurons in the ventral horn. The CS tract (CST) is...

journal_title：Brain structure & function

authors： Olivares-Moreno R,Moreno-Lopez Y,Concha L,Martínez-Lorenzana G,Condés-Lara M,Cordero-Erausquin M,Rojas-Piloni G

更新日期：2017-12-01 00:00:00

abstract：:Previous work in the precocious rodent Octodon degus has shown that exposure to early life stress (ELS) (induced by repeated parental separation) results in changes of excitatory, inhibitory and modulatory transmitter systems in prefrontal and limbic regions of the male brain. The aim of this study was to test the hyp...

journal_title：Brain structure & function

authors： Kunzler J,Braun K,Bock J

更新日期：2015-03-01 00:00:00

abstract：:Understanding the human brain is the ultimate goal in neuroscience, but this is extremely challenging in part due to the fact that brain tissue obtained from autopsy is practically the only source of normal brain tissue and also since changes at different levels of biological organization (genetic, molecular, biochemi...

journal_title：Brain structure & function

authors： Gonzalez-Riano C,Tapia-González S,García A,Muñoz A,DeFelipe J,Barbas C

更新日期：2017-08-01 00:00:00

abstract：:Forebrain serotonin relevant for many psychological disorders arises in the hindbrain, primarily within the dorsal and median raphe nuclei (DR and MR). These nuclei are heterogeneous, containing several distinct groups of serotonin neurons. Here, new insight into the afferent and efferent connectivity of these areas i...

journal_title：Brain structure & function

authors： Commons KG

更新日期：2016-09-01 00:00:00

abstract：:Diffusion tensor imaging (DTI) has become a valuable tool to investigate white matter integrity in the brain. DTI also gives contrast in gray matter, which has been relatively little explored in studies assessing post-injury structural abnormalities. The present study was designed to compare white and gray matter reor...

journal_title：Brain structure & function

authors： Sierra A,Laitinen T,Gröhn O,Pitkänen A

更新日期：2015-03-01 00:00:00

abstract：:The pedunculopontine nucleus (PPN), a cholinergic nucleus of the reticular activating system, is known to be involved in the regulation of sleep and wakefulness. Endogenous and exogenous cannabinoids, by systemic or local administration to the pedunculopontine nucleus, can both influence sleep. We previously demonstra...

journal_title：Brain structure & function

authors： Kovács A,Bordás C,Bíró T,Hegyi Z,Antal M,Szücs P,Pál B

更新日期：2017-01-01 00:00:00

abstract：:We investigated whether pre-operative MRI measures of focal brain atrophy could predict cognitive decline occurring after deep brain stimulation (DBS) of the subthalamic nucleus (STN) in patients with Parkinson's disease (PD). For that purpose, we prospectively collected data of 42 consecutive patients with PD who und...

journal_title：Brain structure & function

authors： Planche V,Munsch F,Pereira B,de Schlichting E,Vidal T,Coste J,Morand D,de Chazeron I,Derost P,Debilly B,Llorca PM,Lemaire JJ,Marques A,Durif F

更新日期：2018-09-01 00:00:00

abstract：:The inner ear is a morphologically complex sensory structure with auditory and vestibular functions. The developing otic epithelium gives rise to neurosensory and non-sensory elements of the adult membranous labyrinth. Extrinsic and intrinsic signals manage the patterning and cell specification of the developing otic ...

journal_title：Brain structure & function

authors： Olaya-Sánchez D,Sánchez-Guardado LÓ,Ohta S,Chapman SC,Schoenwolf GC,Puelles L,Hidalgo-Sánchez M

更新日期：2017-01-01 00:00:00

abstract：:Using sinusoidal oscillations of linear acceleration along both the horizontal and vertical planes to stimulate otolith organs in the inner ear, we charted the postnatal time at which responsive neurons in the rat inferior olive (IO) first showed Fos expression, an indicator of neuronal recruitment into the otolith ci...

journal_title：Brain structure & function

authors： Li C,Han L,Ma CW,Lai SK,Lai CH,Shum DK,Chan YS

更新日期：2013-07-01 00:00:00

abstract：:Prolactin is fundamental for the expression of maternal behaviour. In virgin female rats, prolactin administered upon steroid hormone priming accelerates the onset of maternal care. By contrast, the role of prolactin in mice maternal behaviour remains unclear. This study aims at characterizing central prolactin activi...

journal_title：Brain structure & function

authors： Salais-López H,Lanuza E,Agustín-Pavón C,Martínez-García F

更新日期：2017-03-01 00:00:00