Adolescent cocaine exposure induces prolonged synaptic modifications in medial prefrontal cortex of adult rats.

abstract：:What changes in cortical organisation characterise global and localised variation between humans and chimpanzees remains a topic of considerable interest in evolutionary neuroscience. Here, we examined regional variation in cortical thickness, gyrification and white matter in samples of human and chimpanzee brains. Bo...

journal_title：Brain structure & function

authors： Hopkins WD,Li X,Crow T,Roberts N

更新日期：2017-01-01 00:00:00

abstract：:The purpose of this study was to measure the average corpus callosum volume of normal Koreans (aged in their 20s or 40s) and to analyze the effects of gender, age, and body parameters, such as height and weight on corpus callosum size. Magnetic resonance brain images were recorded for 68 people in their 20s (29 men, 3...

journal_title：Brain structure & function

authors： Lee BY,Sohn JH,Choi MH,Lee SJ,Kim HS,Yang JW,Choi JS,Kim HS,Yi JH,Tack GR,Chung SC

更新日期：2009-09-01 00:00:00

abstract：:Projections from the prefrontal cortex (PFC) to the amygdala (AMG) regulate affective behaviors in a manner that is modulated by dopamine (DA). Although PFC and DA inputs overlap within the basolateral nucleus (BLA) and intercalated cell masses (ICMs), the spatial relationship between these afferents has not been inve...

journal_title：Brain structure & function

authors： Pinto A,Sesack SR

更新日期：2008-09-01 00:00:00

abstract：:Diffusion tensor imaging (DTI) has become a valuable tool to investigate white matter integrity in the brain. DTI also gives contrast in gray matter, which has been relatively little explored in studies assessing post-injury structural abnormalities. The present study was designed to compare white and gray matter reor...

journal_title：Brain structure & function

authors： Sierra A,Laitinen T,Gröhn O,Pitkänen A

更新日期：2015-03-01 00:00:00

abstract：:Striatal fast-spiking interneurons (FSIs) potently inhibit the output neurons of the striatum and, as such, powerfully modulate action learning. Through electrical synaptic coupling, FSIs are theorized to temporally coordinate their activity. This has important implications for their ability to temporally summate inhi...

journal_title：Brain structure & function

authors： Roberts BM,White MG,Patton MH,Chen R,Mathur BN

更新日期：2019-09-01 00:00:00

abstract：:Evidence suggests that extracellular matrix molecules of perivascular basal laminae help orchestrate the molecular assemblies at the gliovascular interface. Specifically, laminin and agrin are thought to tether the dystrophin-associated protein (DAP) complex to the astrocytic basal lamina. This complex includes α-synt...

journal_title：Brain structure & function

authors： Hoddevik EH,Rao SB,Zahl S,Boldt HB,Ottersen OP,Amiry-Moghaddam M

更新日期：2020-03-01 00:00:00

abstract：:We investigated whether pre-operative MRI measures of focal brain atrophy could predict cognitive decline occurring after deep brain stimulation (DBS) of the subthalamic nucleus (STN) in patients with Parkinson's disease (PD). For that purpose, we prospectively collected data of 42 consecutive patients with PD who und...

journal_title：Brain structure & function

authors： Planche V,Munsch F,Pereira B,de Schlichting E,Vidal T,Coste J,Morand D,de Chazeron I,Derost P,Debilly B,Llorca PM,Lemaire JJ,Marques A,Durif F

更新日期：2018-09-01 00:00:00

abstract：:A hierarchical and modular organization is a central hypothesis in the current primate model of auditory cortex (AC) but lacks validation in humans. Here we investigated whether fMRI connectivity at rest and during active tasks is informative of the functional organization of human AC. Identical pitch-varying sounds w...

journal_title：Brain structure & function

authors： Häkkinen S,Rinne T

更新日期：2018-06-01 00:00:00

abstract：:Recently, neuroimaging-based Alzheimer's disease (AD) or mild cognitive impairment (MCI) diagnosis has attracted researchers in the field, due to the increasing prevalence of the diseases. Unfortunately, the unfavorable high-dimensional nature of neuroimaging data, but a limited small number of samples available, make...

journal_title：Brain structure & function

authors： Suk HI,Lee SW,Shen D,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2016-06-01 00:00:00

abstract：:Goal-directed behavior has been shown to be affected by consciously and subliminally induced conflicts. Both types of conflict conjointly modulate behavioral performance, but the underlying neuronal mechanisms have remained unclear. While cognitive control is linked to oscillations in the theta frequency band, there a...

journal_title：Brain structure & function

authors： Bensmann W,Zink N,Mückschel M,Beste C,Stock AK

更新日期：2019-06-01 00:00:00

abstract：:The human visual system is capable of processing visual information from fovea to the far peripheral visual field. Recent fMRI studies have shown a full and detailed retinotopic map in area prostriata, located ventro-dorsally and anterior to the calcarine sulcus along the parieto-occipital sulcus with strong preferenc...

journal_title：Brain structure & function

authors： Kurzawski JW,Mikellidou K,Morrone MC,Pestilli F

更新日期：2020-07-01 00:00:00

abstract：:Recent advances in diffusion-weighted MRI (dMRI) and tractography have enabled identification of major long-range white matter tracts in the human brain. Yet, our understanding of shorter tracts, such as those within the parietal lobe, remains limited. Over a century ago, a tract connecting the superior and inferior p...

journal_title：Brain structure & function

authors： Uesaki M,Takemura H,Ashida H

更新日期：2018-01-01 00:00:00

abstract：:Neuroimaging studies have demonstrated that mental imagery and perception share similar neural substrates, however, there are still ambiguities according to different auditory imagery content. In addition, there is still a lack of information regarding the underlying neural correlation between the two modalities. In t...

journal_title：Brain structure & function

authors： Gu J,Zhang H,Liu B,Li X,Wang P,Wang B

更新日期：2019-11-01 00:00:00

abstract：:Diverse stress stimuli induce long-lasting cognitive deficits, but the underlying molecular mechanisms are still incompletely understood. Here, we report three different stress models demonstrating that stress-inducible increases in microRNA-132 (miR-132) and consequent decreases in its acetylcholinesterase (AChE) tar...

journal_title：Brain structure & function

authors： Shaltiel G,Hanan M,Wolf Y,Barbash S,Kovalev E,Shoham S,Soreq H

更新日期：2013-01-01 00:00:00

abstract：:The default mode network (DMN) in humans has been extensively studied using seed-based correlation analysis (SCA) and independent component analysis (ICA). While DMN has been observed in monkeys as well, there are conflicting reports on whether they exist in rodents. Dogs are higher mammals than rodents, but cognitive...

journal_title：Brain structure & function

authors： Kyathanahally SP,Jia H,Pustovyy OM,Waggoner P,Beyers R,Schumacher J,Barrett J,Morrison EE,Salibi N,Denney TS,Vodyanoy VJ,Deshpande G

更新日期：2015-03-01 00:00:00

abstract：:The frontal cortico-basal ganglia network plays a central role in action selection, associative learning, and motivation, processes requiring the integration of information from functionally distinct cortical regions. The cortico-striatal projection is a likely substrate of information integration, as terminal fields ...

journal_title：Brain structure & function

authors： Heilbronner SR,Meyer MAA,Choi EY,Haber SN

更新日期：2018-07-01 00:00:00

abstract：:The pedunculopontine nucleus (PPN) is composed of neurons with different connectivity patterns that express different neurochemical markers, display distinct firing characteristics and are topographically organized in functional domains across its rostro-caudal axis. Previous reports have shown that the caudal region ...

journal_title：Brain structure & function

authors： Martinez-Gonzalez C,van Andel J,Bolam JP,Mena-Segovia J

更新日期：2014-07-01 00:00:00

abstract：:Understanding the intricate three-dimensional relationship between fiber bundles and subcortical nuclei is not a simple task. It is of paramount importance in neurosciences, especially in the field of functional neurosurgery. The current methods for in vivo and post mortem fiber tract visualization have shortcomings a...

journal_title：Brain structure & function

authors： Alho EJL,Fonoff ET,Di Lorenzo Alho AT,Nagy J,Heinsen H

更新日期：2021-01-03 00:00:00

abstract：:Hippocampal atrophy and neuron loss are commonly found in Alzheimer's disease (AD). However, the underlying molecular mechanisms and the fate in the AD hippocampus of subpopulations of interneurons that express the calcium-binding proteins parvalbumin (PV) and calretinin (CR) has not yet been properly assessed. Using ...

journal_title：Brain structure & function

authors： Takahashi H,Brasnjevic I,Rutten BP,Van Der Kolk N,Perl DP,Bouras C,Steinbusch HW,Schmitz C,Hof PR,Dickstein DL

更新日期：2010-03-01 00:00:00

abstract：:Coordinated modulation of sympathetic and parasympathetic nervous activity is required for physiological regulation of tissue function. Anatomically, whilst the peripheral sympathetic and parasympathetic pathways are separate, the distribution of premotor neurons in higher brain regions often overlaps. This co-distrib...

journal_title：Brain structure & function

authors： Hettigoda NS,Fong AY,Badoer E,McKinley MJ,Oldfield BJ,Allen AM

更新日期：2015-07-01 00:00:00

abstract：:Despite robust sex differences in behavioral responses to drugs of abuse, relatively little is known about structural sex differences in synaptic connectivity of reward circuits such as in the nucleus accumbens (NAc). Previously, we showed that distal dendritic spine density on medium spiny neurons in the NAc is highe...

journal_title：Brain structure & function

authors： Wissman AM,May RM,Woolley CS

更新日期：2012-04-01 00:00:00

abstract：:Cytoarchitectonic characterization of borders is necessary for stereological studies (e.g., total cell number estimation), in which particular cortical areas have to be defined. In this study, cytoarchitectonic characteristics are described and illustrated for the rat ventral or orbital frontal cortical areas, i.e., t...

journal_title：Brain structure & function

authors： Van De Werd HJ,Uylings HB

更新日期：2008-02-01 00:00:00

abstract：:Individuals with Down syndrome (DS) exhibit intellectual disability and develop Alzheimer's disease-like neuropathology during the third decade of life. The Ts65Dn mouse model of DS exhibits key features of both disorders, including impairments in learning, attention and memory, as well as atrophy of basal forebrain c...

journal_title：Brain structure & function

authors： Powers BE,Velazquez R,Kelley CM,Ash JA,Strawderman MS,Alldred MJ,Ginsberg SD,Mufson EJ,Strupp BJ

更新日期：2016-12-01 00:00:00

abstract：:Chemically mediated synaptic transmission results from fusion of synaptic vesicles with the presynaptic plasma membrane, subsequent release of the vesicular content into the cleft and binding to postsynaptic receptors. Previous modelling studies of excitatory neurotransmitter glutamate were based on simplified geometr...

journal_title：Brain structure & function

authors： Boucher J,Kröger H,Sík A

更新日期：2010-07-01 00:00:00

abstract：:Brain pathology in Friedreich ataxia is characterized by progressive degeneration of nervous tissue in the brainstem, cerebellum and cerebellar peduncles. Evidence of cerebral involvement is however equivocal. This brain imaging study investigates cerebello-cerebral white matter connectivity in Friedreich ataxia with ...

journal_title：Brain structure & function

authors： Zalesky A,Akhlaghi H,Corben LA,Bradshaw JL,Delatycki MB,Storey E,Georgiou-Karistianis N,Egan GF

更新日期：2014-05-01 00:00:00

abstract：:The hippocampal formation is important for higher brain functions such as spatial navigation and the consolidation of memory, and it contributes to abilities thought to be uniquely human, yet little is known about how the human hippocampal formation compares to that of our closest living relatives, the chimpanzees. To...

journal_title：Brain structure & function

authors： Rogers Flattery CN,Rosen RF,Farberg AS,Dooyema JM,Hof PR,Sherwood CC,Walker LC,Preuss TM

更新日期：2020-11-01 00:00:00

abstract：:The present study documents the morphology of neurons in several regions of the neocortex from the bottlenose dolphin (Tursiops truncatus), the North Atlantic minke whale (Balaenoptera acutorostrata), and the humpback whale (Megaptera novaeangliae). Golgi-stained neurons (n = 210) were analyzed in the frontal and temp...

journal_title：Brain structure & function

authors： Butti C,Janeway CM,Townshend C,Wicinski BA,Reidenberg JS,Ridgway SH,Sherwood CC,Hof PR,Jacobs B

更新日期：2015-11-01 00:00:00

abstract：:Network-level analysis based on anatomical, pairwise similarities (e.g., cortical thickness) has been gaining increasing attention recently. However, there has not been a systematic study of the impact of spatial scale and edge definitions on predictive performance, which is necessary to obtain a clear understanding o...

journal_title：Brain structure & function

authors： Raamana PR,Strother SC,Australian Imaging Biomarkers, Lifestyle flagship study of ageing, for The Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2020-11-01 00:00:00

abstract：:Serum response factor (SRF) is a major transcription factor that regulates the expression of several plasticity-associated genes in the brain. Although the developmental expression of SRF in excitatory neurons is crucial for establishing proper hippocampal circuitry, no substantial evidence of its role in unstimulated...

journal_title：Brain structure & function

authors： Nader K,Krysiak A,Beroun A,Pekala M,Szymanska M,Kuzniewska B,Radwanska K,Kaczmarek L,Kalita K

更新日期：2019-11-01 00:00:00

abstract：:Glutamatergic afferents from the cerebral cortex are the main excitatory drive of striatal projection neurons. The metabotropic glutamate receptor 4 (mGluR4) presynaptically modulates transmission at corticostriatal synapses, and is considered as a potent drug target for Parkinson's disease and other brain disorders. ...

journal_title：Brain structure & function

authors： Iskhakova L,Smith Y

更新日期：2016-12-01 00:00:00