Neuronal networks underlying the conjoint modulation of response selection by subliminal and consciously induced cognitive conflicts.

Abstract:

:Goal-directed behavior has been shown to be affected by consciously and subliminally induced conflicts. Both types of conflict conjointly modulate behavioral performance, but the underlying neuronal mechanisms have remained unclear. While cognitive control is linked to oscillations in the theta frequency band, there are several mechanisms via which theta oscillations may enable cognitive control: via the coordination and synchronization of a large and complex neuronal network and/or via local processes within the medial frontal cortex. We, therefore, investigated this issue with a focus on theta oscillations and the underlying neuronal networks. For this purpose, n = 40 healthy young participants performed a conflict paradigm that combines conscious and subliminal distractors while an EEG was recorded. The data show that separate processes modulate the theta-based activation and organization of cognitive control networks: EEG beamforming analyses showed that variations in theta band power generated in the supplementary motor area reflected the need for control and task-relevant goal shielding, as both conflicts as well as their conjoint effect on behavior increased theta power. Yet, large networks were not modulated by this and graph theoretical analyses of the efficiency (i.e. small worldness) of theta-driven networks did not reflect the need for control. Instead, theta network efficiency was decreased by subliminal conflicts only. This dissociation suggests that while both kinds of conflict require control and goal shielding, which are induced by an increase in theta band power and modulate processes in the medial frontal cortex, only non-conscious conflicts diminish the efficiency of theta-driven large-scale networks.

journal_name

Brain Struct Funct

authors

Bensmann W,Zink N,Mückschel M,Beste C,Stock AK

doi

10.1007/s00429-019-01866-0

subject

Has Abstract

pub_date

2019-06-01 00:00:00

pages

1697-1709

issue

5

eissn

1863-2653

issn

1863-2661

pii

10.1007/s00429-019-01866-0

journal_volume

224

pub_type

杂志文章
  • Hippocampal signatures of awake targeted memory reactivation.

    abstract::Dominant theories of episodic memory propose that a key mechanism of memory consolidation is replay-a process, whereby neural patterns of activation during learning are reinstated during offline post-learning periods. Here, we tested whether key signatures of replay defined by studies in rodents, such as recapitulatio...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-018-1790-2

    authors: Alm KH,Ngo CT,Olson IR

    更新日期:2019-03-01 00:00:00

  • Saliency, switching, attention and control: a network model of insula function.

    abstract::The insula is a brain structure implicated in disparate cognitive, affective, and regulatory functions, including interoceptive awareness, emotional responses, and empathic processes. While classically considered a limbic region, recent evidence from network analysis suggests a critical role for the insula, particular...

    journal_title:Brain structure & function

    pub_type: 杂志文章,评审

    doi:10.1007/s00429-010-0262-0

    authors: Menon V,Uddin LQ

    更新日期:2010-06-01 00:00:00

  • Formation of GABAA receptor complexes containing α1 and α5 subunits is paralleling a multiple T-maze learning task in mice.

    abstract::There is limited information on the role of GABA type A receptors (GABAARs) containing α1, α5 and γ2 subunits in learning and memory. Here, we assessed the possible role of such receptors in spatial learning using the multiple T-maze (MTM) paradigm. C57BL/6J mice were trained in the MTM which induced elevated levels o...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-016-1233-x

    authors: Ghafari M,Falsafi SK,Szodorai E,Kim EJ,Li L,Höger H,Berger J,Fuchs K,Sieghart W,Lubec G

    更新日期:2017-01-01 00:00:00

  • SK- and h-current contribute to the generation of theta-like resonance of rat substantia nigra pars compacta dopaminergic neurons at hyperpolarized membrane potentials.

    abstract::Oscillation activities are the feature of neural network and correlated to different physiological states. The theta (θ) oscillation (2-7 Hz) has been reported in the basal ganglia, and the intrinsic resonance properties of individual neurons have provided a basis for this network oscillation. The basal ganglia neuron...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-011-0361-6

    authors: Xue WN,Wang Y,He SM,Wang XL,Zhu JL,Gao GD

    更新日期:2012-04-01 00:00:00

  • Decreasing predictability of visual motion enhances feed-forward processing in visual cortex when stimuli are behaviorally relevant.

    abstract::Recent views of information processing in the (human) brain emphasize the hierarchical structure of the central nervous system, which is assumed to form the basis of a functional hierarchy. Hierarchical predictive processing refers to the notion that higher levels try to predict activity in lower areas, while lower le...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-016-1251-8

    authors: Kellermann T,Scholle R,Schneider F,Habel U

    更新日期:2017-03-01 00:00:00

  • Anatomical analysis of afferent projections to the medial prefrontal cortex in the rat.

    abstract::The medial prefrontal cortex (mPFC) has been associated with diverse functions including attentional processes, visceromotor activity, decision making, goal directed behavior, and working memory. Using retrograde tracing techniques, we examined, compared, and contrasted afferent projections to the four divisions of th...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-007-0150-4

    authors: Hoover WB,Vertes RP

    更新日期:2007-09-01 00:00:00

  • Anterior-posterior dissociation of the default mode network in dogs.

    abstract::The default mode network (DMN) in humans has been extensively studied using seed-based correlation analysis (SCA) and independent component analysis (ICA). While DMN has been observed in monkeys as well, there are conflicting reports on whether they exist in rodents. Dogs are higher mammals than rodents, but cognitive...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-013-0700-x

    authors: Kyathanahally SP,Jia H,Pustovyy OM,Waggoner P,Beyers R,Schumacher J,Barrett J,Morrison EE,Salibi N,Denney TS,Vodyanoy VJ,Deshpande G

    更新日期:2015-03-01 00:00:00

  • Absolute and relative pitch processing in the human brain: neural and behavioral evidence.

    abstract::Pitch is a primary perceptual dimension of sounds and is crucial in music and speech perception. When listening to melodies, most humans encode the relations between pitches into memory using an ability called relative pitch (RP). A small subpopulation, almost exclusively musicians, preferentially encode pitches using...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-019-01872-2

    authors: Leipold S,Brauchli C,Greber M,Jäncke L

    更新日期:2019-06-01 00:00:00

  • α5 nAChR modulation of the prefrontal cortex makes attention resilient.

    abstract::A loss-of-function polymorphism in the α5 nicotinic acetylcholine receptor (nAChR) subunit gene has been linked to both drug abuse and schizophrenia. The α5 nAChR subunit is strategically positioned in the prefrontal cortex (PFC), where a loss-of-function in this subunit may contribute to cognitive disruptions in both...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-017-1601-1

    authors: Howe WM,Brooks JL,Tierney PL,Pang J,Rossi A,Young D,Dlugolenski K,Guillmette E,Roy M,Hales K,Kozak R

    更新日期:2018-03-01 00:00:00

  • Immunohistochemical and biochemical evidence for the presence of serotonin-containing neurons and nerve fibers in the octopus arm.

    abstract::The octopus arm contains a tridimensional array of muscles with a massive sensory-motor system. We herein provide the first evidence for the existence of serotonin (5-HT) in the octopus arm nervous system and investigated its distribution using immunohistochemistry. 5-HT-like immunoreactive (5-HT-lir) nerve cell bodie...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-017-1385-3

    authors: Bellier JP,Xie Y,Farouk SM,Sakaue Y,Tooyama I,Kimura H

    更新日期:2017-09-01 00:00:00

  • Sucrose-induced plasticity in the basolateral amygdala in a 'comfort' feeding paradigm.

    abstract::A history of intermittent, limited sucrose intake (LSI) attenuates the hypothalamic-pituitary-adrenocortical (HPA) axis stress response, and neuronal activity in the basolateral amygdala (BLA) is necessary for this HPA-dampening. LSI increases the expression of plasticity-associated genes in the BLA; however, the natu...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-017-1454-7

    authors: Packard AEB,Di S,Egan AE,Fourman SM,Tasker JG,Ulrich-Lai YM

    更新日期:2017-12-01 00:00:00

  • Differential neuronal changes in medial prefrontal cortex, basolateral amygdala and nucleus accumbens after postweaning social isolation.

    abstract::The mesocorticolimbic system contains dopamine (DA)-producing neurons in the ventral tegmental area (VTA) and their projection targets, including the medial prefrontal cortex (mPFC), amygdala (AMY) and nucleus accumbens (NAc). Disruption of this system might attribute to mental illnesses. In the present study, we adop...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-011-0355-4

    authors: Wang YC,Ho UC,Ko MC,Liao CC,Lee LJ

    更新日期:2012-04-01 00:00:00

  • Differential impact of chronic stress along the hippocampal dorsal-ventral axis.

    abstract::Stress impacts differently in distinct brain regions. However, so far few studies have focused on the differential responses triggered by stressful stimuli on the intrinsic functional heterogeneity of the hippocampal axis. In this study, we assessed the functional and structural alterations caused by exposure to a chr...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-014-0713-0

    authors: Pinto V,Costa JC,Morgado P,Mota C,Miranda A,Bravo FV,Oliveira TG,Cerqueira JJ,Sousa N

    更新日期:2015-03-01 00:00:00

  • Neurochemically distinct circuitry regulates locus coeruleus activity during female social stress depending on coping style.

    abstract::Stress-related psychiatric diseases are nearly twice as prevalent in women compared to men. We recently showed in male rats that the resident-intruder model of social stress differentially engages stress-related circuitry that regulates norepinephrine-containing neurons of the locus coeruleus (LC) depending on coping ...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-019-01837-5

    authors: Reyes BAS,Zhang XY,Dufourt EC,Bhatnagar S,Valentino RJ,Van Bockstaele EJ

    更新日期:2019-05-01 00:00:00

  • Orienting movements in area 9 identified by long-train ICMS.

    abstract::The effect of intracortical microstimulation has been studied in several cortical areas from motor to sensory areas. The frontal pole has received particular attention, and several microstimulation studies have been conducted in the frontal eye field, supplementary eye field, and the premotor ear-eye field, but no mic...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-013-0682-8

    authors: Lanzilotto M,Perciavalle V,Lucchetti C

    更新日期:2015-03-01 00:00:00

  • Increased hippocampal excitability and impaired spatial memory function in mice lacking VGLUT2 selectively in neurons defined by tyrosine hydroxylase promoter activity.

    abstract::Three populations of neurons expressing the vesicular glutamate transporter 2 (Vglut2) were recently described in the A10 area of the mouse midbrain, of which two populations were shown to express the gene encoding, the rate-limiting enzyme for catecholamine synthesis, tyrosine hydroxylase (TH).One of these population...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-014-0778-9

    authors: Nordenankar K,Smith-Anttila CJ,Schweizer N,Viereckel T,Birgner C,Mejia-Toiber J,Morales M,Leao RN,Wallén-Mackenzie Å

    更新日期:2015-07-01 00:00:00

  • Cognitive subtypes of dyslexia are characterized by distinct patterns of grey matter volume.

    abstract::The variety of different causal theories together with inconsistencies about the anatomical brain markers emphasize the heterogeneity of developmental dyslexia. Attempts were made to test on a behavioral level the existence of subtypes of dyslexia showing distinguishable cognitive deficits. Importantly, no research wa...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-013-0595-6

    authors: Jednoróg K,Gawron N,Marchewka A,Heim S,Grabowska A

    更新日期:2014-09-01 00:00:00

  • Detection of cannabinoid receptors CB1 and CB2 within basal ganglia output neurons in macaques: changes following experimental parkinsonism.

    abstract::Although type 1 cannabinoid receptors (CB1Rs) are expressed abundantly throughout the brain, the presence of type 2 cannabinoid receptors (CB2Rs) in neurons is still somewhat controversial. Taking advantage of newly designed CB1R and CB2R mRNA riboprobes, we demonstrate by PCR and in situ hybridization that transcript...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-014-0823-8

    authors: Sierra S,Luquin N,Rico AJ,Gómez-Bautista V,Roda E,Dopeso-Reyes IG,Vázquez A,Martínez-Pinilla E,Labandeira-García JL,Franco R,Lanciego JL

    更新日期:2015-09-01 00:00:00

  • Quantification of neurons in the hippocampal formation of chimpanzees: comparison to rhesus monkeys and humans.

    abstract::The hippocampal formation is important for higher brain functions such as spatial navigation and the consolidation of memory, and it contributes to abilities thought to be uniquely human, yet little is known about how the human hippocampal formation compares to that of our closest living relatives, the chimpanzees. To...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-020-02139-x

    authors: Rogers Flattery CN,Rosen RF,Farberg AS,Dooyema JM,Hof PR,Sherwood CC,Walker LC,Preuss TM

    更新日期:2020-11-01 00:00:00

  • Right insula for our sense of limb ownership and self-awareness of actions.

    abstract::Normally, we are aware that our arms and legs belong to us and not to someone else. However, some stroke patients with hemiparesis/-plegia after right-sided stroke show a disturbed sensation of limb ownership and a disturbed self-awareness of actions and such patients with anosognosia for hemiparesis/plegia typically ...

    journal_title:Brain structure & function

    pub_type: 杂志文章,评审

    doi:10.1007/s00429-010-0250-4

    authors: Karnath HO,Baier B

    更新日期:2010-06-01 00:00:00

  • The neostriatum: two entities, one structure?

    abstract::The striosome (or patch) was first identified with anatomical techniques as neurons organized in a three-dimensional labyrinth inserted in and interdigitating the rest of neostriatum: the matrix. Striosome and matrix rapidly became known as two neuronal compartments expressing different biochemical markers, embryonic ...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-015-1000-4

    authors: Lopez-Huerta VG,Nakano Y,Bausenwein J,Jaidar O,Lazarus M,Cherassse Y,Garcia-Munoz M,Arbuthnott G

    更新日期:2016-04-01 00:00:00

  • Ultrastructural analysis of prefrontal cortical inputs to the rat amygdala: spatial relationships to presumed dopamine axons and D1 and D2 receptors.

    abstract::Projections from the prefrontal cortex (PFC) to the amygdala (AMG) regulate affective behaviors in a manner that is modulated by dopamine (DA). Although PFC and DA inputs overlap within the basolateral nucleus (BLA) and intercalated cell masses (ICMs), the spatial relationship between these afferents has not been inve...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-008-0180-6

    authors: Pinto A,Sesack SR

    更新日期:2008-09-01 00:00:00

  • Structural MRI studies of language function in the undamaged brain.

    abstract::In recent years, the demonstration that structural changes can occur in the human brain beyond those associated with development, ageing and neuropathology has revealed a new approach to studying the neural basis of behaviour. In this review paper, we focus on structural imaging studies of language that have utilised ...

    journal_title:Brain structure & function

    pub_type: 杂志文章,评审

    doi:10.1007/s00429-009-0211-y

    authors: Richardson FM,Price CJ

    更新日期:2009-10-01 00:00:00

  • Quantitative mapping of the local and extrinsic sources of GABA and Reelin to the layer Ia neuropil in the adult rat neocortex.

    abstract::Inputs to apical dendritic tufts have been considered to be crucial for associative learning, attention and similar ''feedback'' interactions and are located in neocortical layer Ia. Excitatory thalamic projections to apical tufts in layer Ia have been well characterized and their role in the cortical circuit has been...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-013-0591-x

    authors: Ramos-Moreno T,Clascá F

    更新日期:2014-09-01 00:00:00

  • Ghrelin receptor signaling targets segregated clusters of neurons within the nucleus of the solitary tract.

    abstract::Ghrelin is a stomach-derived hormone that regulates a variety of biological functions such as food intake, gastrointestinal function and blood glucose metabolism, among others. Ghrelin acts via the growth hormone secretagogue receptor (GHSR), a G-protein-coupled receptor located in key brain areas that mediate specifi...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-018-1682-5

    authors: Cornejo MP,De Francesco PN,García Romero G,Portiansky EL,Zigman JM,Reynaldo M,Perello M

    更新日期:2018-09-01 00:00:00

  • Interactions of genetic variants reveal inverse modulation patterns of dopamine system on brain gray matter volume and resting-state functional connectivity in healthy young adults.

    abstract::Different genotypic combinations of COMT and DRD2 can generate multiple subgroups with different levels of dopamine signaling. Its modulations on brain properties can be investigated by analyzing the combined gene effects of COMT and DRD2. However, the inherent association between modulation patterns of the dopamine s...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-015-1134-4

    authors: Xu J,Qin W,Liu B,Jiang T,Yu C

    更新日期:2016-11-01 00:00:00

  • A 3-dimensional digital atlas of the ascending sensory and the descending motor systems in the pigeon brain.

    abstract::Pigeons are classic animal models for learning, memory, and cognition. The majority of the current understanding about avian neurobiology outside of the domain of the song system has been established using pigeons. Since MRI represents an increasingly relevant tool for comparative neuroscience, a 3-dimensional MRI-bas...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-012-0400-y

    authors: Güntürkün O,Verhoye M,De Groof G,Van der Linden A

    更新日期:2013-01-01 00:00:00

  • Use of computational fluid dynamics for 3D fiber tract visualization on human high-thickness histological slices: histological mesh tractography.

    abstract::Understanding the intricate three-dimensional relationship between fiber bundles and subcortical nuclei is not a simple task. It is of paramount importance in neurosciences, especially in the field of functional neurosurgery. The current methods for in vivo and post mortem fiber tract visualization have shortcomings a...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-020-02187-3

    authors: Alho EJL,Fonoff ET,Di Lorenzo Alho AT,Nagy J,Heinsen H

    更新日期:2021-01-03 00:00:00

  • Activity-dependent and graded BACE1 expression in the olfactory epithelium is mediated by the retinoic acid metabolizing enzyme CYP26B1.

    abstract::It is well established that environmental influences play a key role in sculpting neuronal connectivity in the brain. One example is the olfactory sensory map of topographic axonal connectivity. While intrinsic odorant receptor signaling in olfactory sensory neurons (OSN) determines anterior-posterior counter gradient...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-014-0783-z

    authors: Login H,Butowt R,Bohm S

    更新日期:2015-07-01 00:00:00

  • Synaptic mechanisms underlying the intense firing of neocortical layer 5B pyramidal neurons in response to cortico-cortical inputs.

    abstract::In the neocortex, large layer 5B pyramidal neurons implement a high-density firing code. In contrast, other subtypes of pyramidal neurons, including those in layer 2/3, are functionally characterized by their sparse firing rate. Here, we investigate the synaptic basis of this behavior by comparing the properties of th...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-019-01842-8

    authors: Sempere-Ferràndez A,Martínez S,Geijo-Barrientos E

    更新日期:2019-05-01 00:00:00