Hippocampal interneuron loss in an APP/PS1 double mutant mouse and in Alzheimer's disease.

abstract：:A recent virtual-lesion study using inhibitory repetitive transcranial magnetic stimulation (rTMS) confirmed the causal behavioral relevance of the precuneus in the evaluation of one's own memory performance (aka mnemonic metacognition). This study's goal is to elucidate how these TMS-induced neuromodulatory effects m...

journal_title：Brain structure & function

authors： Ye Q,Zou F,Dayan M,Lau H,Hu Y,Kwok SC

更新日期：2019-09-01 00:00:00

abstract：:Retinoic acid, the active form of the nutrient vitamin A, regulates several facets of neuronal plasticity in the hippocampus, including neurogenesis and synaptic strength, acting via specific retinoic acid receptors (RARs). Essential for conversion of vitamin A to retinoic acid is the enzyme retinaldehyde dehydrogenas...

journal_title：Brain structure & function

authors： Fragoso YD,Shearer KD,Sementilli A,de Carvalho LV,McCaffery PJ

更新日期：2012-04-01 00:00:00

abstract：:A history of intermittent, limited sucrose intake (LSI) attenuates the hypothalamic-pituitary-adrenocortical (HPA) axis stress response, and neuronal activity in the basolateral amygdala (BLA) is necessary for this HPA-dampening. LSI increases the expression of plasticity-associated genes in the BLA; however, the natu...

journal_title：Brain structure & function

authors： Packard AEB,Di S,Egan AE,Fourman SM,Tasker JG,Ulrich-Lai YM

更新日期：2017-12-01 00:00:00

abstract：:Childhood is defined by the development of cognitive abilities as well as brain growth and function. While prior neuroimaging studies have investigated early development fragmentally, we studied the typical development of functional network connectivity continuously from infancy to childhood (average of 24 months) in ...

journal_title：Brain structure & function

authors： Bruchhage MMK,Ngo GC,Schneider N,D'Sa V,Deoni SCL

更新日期：2020-03-01 00:00:00

abstract：:Manual volumetric measurement of the brain's frontal lobe and its subregions from magnetic resonance images (MRIs) is an established method for researching neural correlates of clinical disorders or cognitive functions. However, there is no consensus between methods used to identify relevant boundaries of a given regi...

journal_title：Brain structure & function

authors： Cox SR,Ferguson KJ,Royle NA,Shenkin SD,MacPherson SE,MacLullich AM,Deary IJ,Wardlaw JM

更新日期：2014-01-01 00:00:00

abstract：:Interest in the study of brain connectivity is growing, particularly in understanding the dynamics of the structural/functional connectivity relation. Structural and functional connectivity are most often analysed independently of each other. Track-weighted functional connectivity (TW-FC) was recently proposed as a me...

journal_title：Brain structure & function

authors： Calamante F,Smith RE,Liang X,Zalesky A,Connelly A

更新日期：2017-11-01 00:00:00

abstract：:The primary systems framework has been used to relate behavioural performance across many different language activities to the status of core underpinning domain-general cognitive systems. This study provided the first quantitative investigation of this account at both behavioural and neural levels in a group of patie...

journal_title：Brain structure & function

authors： Woollams AM,Halai A,Lambon Ralph MA

更新日期：2018-11-01 00:00:00

abstract：:The fornix is the primary efferent pathway of the hippocampus and plays a central role in memory circuitry. Diffusion tensor imaging has shown changes in the fornix with typical development and aging. Here, the fornix was investigated in 903 healthy young adult participants aged 22-36 years old from the high-spatial r...

journal_title：Brain structure & function

authors： Cahn AJ,Little G,Beaulieu C,Tétreault P

更新日期：2021-01-02 00:00:00

abstract：:The rostral nucleus of the solitary tract (rNST) receives gustatory input via chorda tympani (CT) afferents from the anterior two-thirds of the tongue and transmits it to higher brain regions. To help understand how the gustatory information is processed at the 1st relay nucleus of the brain stem, we investigated the ...

journal_title：Brain structure & function

authors： Park SK,Lee DS,Bae JY,Bae YC

更新日期：2016-03-01 00:00:00

abstract：:The functional specificity of brain areas is diminished with age and accompanied by the recruitment of additional brain regions in healthy older adults. This process has repeatedly been demonstrated within distinct functional domains, in particular the visual system. However, it is yet unclear, whether this phenomenon...

journal_title：Brain structure & function

authors： Roski C,Caspers S,Lux S,Hoffstaedter F,Bergs R,Amunts K,Eickhoff SB

更新日期：2014-03-01 00:00:00

abstract：:Proprioceptive signals from body muscles have historically been considered to project to the rostrodorsal shell of the ventrobasal thalamic complex [the ventral posterolateral nucleus (VPL) and ventral posteromedial nucleus (VPM)]. However, we have recently found that proprioception from rat jaw-closing muscle spindle...

journal_title：Brain structure & function

authors： Uemura Y,Haque T,Sato F,Tsutsumi Y,Ohara H,Oka A,Furuta T,Bae YC,Yamashiro T,Tachibana Y,Yoshida A

更新日期：2020-09-01 00:00:00

abstract：:Neocortical layer VI is critically involved in thalamocortical activity changes during the sleep/wake cycle. It receives dense projections from thalamic nuclei sensitive to the wake-promoting neuropeptides orexins, and its deepest part, layer VIb, is the only cortical lamina reactive to orexins. This convergence of wa...

journal_title：Brain structure & function

authors： Hay YA,Andjelic S,Badr S,Lambolez B

更新日期：2015-11-01 00:00:00

abstract：:The neural underpinnings of human emotional expression are thought to be unevenly distributed among the two brain hemispheres. However, little is known on the anatomy supporting this claim, particularly in the cerebral white matter. Here, we explored the relationship between hemi-face dominance in emotional expression...

journal_title：Brain structure & function

authors： Ioannucci S,George N,Friedrich P,Cerliani L,Thiebaut de Schotten M

更新日期：2020-05-01 00:00:00

abstract：:Recent advances in diffusion-weighted MRI (dMRI) and tractography have enabled identification of major long-range white matter tracts in the human brain. Yet, our understanding of shorter tracts, such as those within the parietal lobe, remains limited. Over a century ago, a tract connecting the superior and inferior p...

journal_title：Brain structure & function

authors： Uesaki M,Takemura H,Ashida H

更新日期：2018-01-01 00:00:00

abstract：:Similar to memory formation, memory extinction is also a new learning process that requires synaptic plasticity. Actin rearrangement is fundamental for synaptic plasticity, however, whether actin rearrangement in the infralimbic cortex (IL) plays a role in memory extinction, as well as the mechanisms underlying it, re...

journal_title：Brain structure & function

authors： Bi AL,Wang Y,Zhang S,Li BQ,Sun ZP,Bi HS,Chen ZY

更新日期：2015-03-01 00:00:00

abstract：:Growing evidence indicates that physical exercise increases hippocampal volume. This has consistently been shown in mice and men using magnetic resonance imaging. On the other hand, histological studies have reported profound alterations on a cellular level including increased adult hippocampal neurogenesis after exer...

journal_title：Brain structure & function

authors： Biedermann SV,Fuss J,Steinle J,Auer MK,Dormann C,Falfán-Melgoza C,Ende G,Gass P,Weber-Fahr W

更新日期：2016-04-01 00:00:00

abstract：:The frontotemporal cortical network is associated with behaviours such as impulsivity and aggression. The health of the uncinate fasciculus (UF) that connects the orbitofrontal cortex (OFC) with the anterior temporal lobe (ATL) may be a crucial determinant of behavioural regulation. Behavioural changes can emerge afte...

journal_title：Brain structure & function

authors： Goswami R,Dufort P,Tartaglia MC,Green RE,Crawley A,Tator CH,Wennberg R,Mikulis DJ,Keightley M,Davis KD

更新日期：2016-05-01 00:00:00

abstract：:The acoustic radiation is a compact bundle of fibers conveying auditory information from the medial geniculate nucleus of the thalamus to the auditory cortex. Topographical knowledge of this bundle in primates is scarce and in vivo diffusion-based tractography reconstructions in humans remains challenging, especially ...

journal_title：Brain structure & function

authors： Maffei C,Jovicich J,De Benedictis A,Corsini F,Barbareschi M,Chioffi F,Sarubbo S

更新日期：2018-01-01 00:00:00

abstract：:Chemically mediated synaptic transmission results from fusion of synaptic vesicles with the presynaptic plasma membrane, subsequent release of the vesicular content into the cleft and binding to postsynaptic receptors. Previous modelling studies of excitatory neurotransmitter glutamate were based on simplified geometr...

journal_title：Brain structure & function

authors： Boucher J,Kröger H,Sík A

更新日期：2010-07-01 00:00:00

abstract：:Recent studies of the neurobiology of the dorsal frontal cortex (FC) of the ferret have illuminated its key role in the attention network, top-down cognitive control of sensory processing, and goal directed behavior. To elucidate the neuroanatomical regions of the dorsal FC, and delineate the boundary between premotor...

journal_title：Brain structure & function

authors： Radtke-Schuller S,Town SM,Yin P,Elgueda D,Schuller G,Bizley JK,Shamma SA,Fritz JB

更新日期：2020-06-01 00:00:00

abstract：:Striatal fast-spiking interneurons (FSIs) potently inhibit the output neurons of the striatum and, as such, powerfully modulate action learning. Through electrical synaptic coupling, FSIs are theorized to temporally coordinate their activity. This has important implications for their ability to temporally summate inhi...

journal_title：Brain structure & function

authors： Roberts BM,White MG,Patton MH,Chen R,Mathur BN

更新日期：2019-09-01 00:00:00

abstract：:MRI was employed to follow the neurodegenerative foci and the localization of inflammatory cells by magnetically labeled CD4+ or CD8+ lymphocytes in the ischemia/reperfusion long-lived rats (9 and 13 months after 10 min of cardiac arrest). MRI of ischemic rats showed: (1) blood-brain barrier (BBB) leakage in the area ...

journal_title：Brain structure & function

authors： Sekeljic V,Bataveljic D,Stamenkovic S,Ułamek M,Jabłoński M,Radenovic L,Pluta R,Andjus PR

更新日期：2012-04-01 00:00:00

abstract：:Pigeons are classic animal models for learning, memory, and cognition. The majority of the current understanding about avian neurobiology outside of the domain of the song system has been established using pigeons. Since MRI represents an increasingly relevant tool for comparative neuroscience, a 3-dimensional MRI-bas...

journal_title：Brain structure & function

authors： Güntürkün O,Verhoye M,De Groof G,Van der Linden A

更新日期：2013-01-01 00:00:00

abstract：:Cerebellar volume declines with aging. Few studies have investigated age differences in regional cerebellar volume (RCV) and their association with motor and cognitive function. In 213 healthy older adults, we investigated the association of age with motor skills, cognition and RCV. Subsequently, we studied the associ...

journal_title：Brain structure & function

authors： Koppelmans V,Hoogendam YY,Hirsiger S,Mérillat S,Jäncke L,Seidler RD

更新日期：2017-05-01 00:00:00

abstract：:Agenesis of the corpus callosum (AgCC) is a congenital condition associated with wide-ranging emotional and social impairments often overlapping with the diagnostic criteria for autism. Mapping functional connectivity in the acallosal brain can help identify neural correlates of the deficits associated with this condi...

journal_title：Brain structure & function

authors： Sforazzini F,Bertero A,Dodero L,David G,Galbusera A,Scattoni ML,Pasqualetti M,Gozzi A

更新日期：2016-03-01 00:00:00

abstract：:Prolactin is fundamental for the expression of maternal behaviour. In virgin female rats, prolactin administered upon steroid hormone priming accelerates the onset of maternal care. By contrast, the role of prolactin in mice maternal behaviour remains unclear. This study aims at characterizing central prolactin activi...

journal_title：Brain structure & function

authors： Salais-López H,Lanuza E,Agustín-Pavón C,Martínez-García F

更新日期：2017-03-01 00:00:00

abstract：:Matrix metalloproteinases (MMPs) are Zn(2+)-dependent endopeptidases considered to be essential for normal brain development and neuroplasticity by modulating extracellular matrix proteins, receptors, adhesion molecules, growth factors and cytoskeletal proteins. Specifically, MMP-3 has recently been implicated in syna...

journal_title：Brain structure & function

authors： Aerts J,Nys J,Moons L,Hu TT,Arckens L

更新日期：2015-09-01 00:00:00

abstract：:Regulator of G protein signaling 14 (RGS14) is a multifunctional signaling protein primarily expressed in mouse pyramidal neurons of hippocampal area CA2 where it regulates synaptic plasticity important for learning and memory. However, very little is known about RGS14 protein expression in the primate brain. Here, we...

journal_title：Brain structure & function

authors： Squires KE,Gerber KJ,Pare JF,Branch MR,Smith Y,Hepler JR

更新日期：2018-01-01 00:00:00

abstract：:Previous diffusion tensor imaging (DTI) studies have shown that various factors can affect white matter (WM) tract diffusivity. The aim of the present study was to investigate the effects of childhood adversity (CA), age and gender on WM diffusivity in tracts that are thought to be involved in emotional regulation in ...

journal_title：Brain structure & function

authors： Ugwu ID,Amico F,Carballedo A,Fagan AJ,Frodl T

更新日期：2015-07-01 00:00:00

abstract：:Sensory neurons of the jugular vagal ganglia innervate the respiratory tract and project to the poorly studied medullary paratrigeminal nucleus. In the present study, we used neuroanatomical tracing, pharmacology and physiology in guinea pig to investigate the paratrigeminal neural circuits mediating jugular ganglia-e...

journal_title：Brain structure & function

authors： Driessen AK,Farrell MJ,Dutschmann M,Stanic D,McGovern AE,Mazzone SB

更新日期：2018-12-01 00:00:00