Abstract:
:Recent studies of the neurobiology of the dorsal frontal cortex (FC) of the ferret have illuminated its key role in the attention network, top-down cognitive control of sensory processing, and goal directed behavior. To elucidate the neuroanatomical regions of the dorsal FC, and delineate the boundary between premotor cortex (PMC) and dorsal prefrontal cortex (dPFC), we placed retrograde tracers in adult ferret dorsal FC anterior to primary motor cortex and analyzed thalamo-cortical connectivity. Cyto- and myeloarchitectural differences across dorsal FC and the distinctive projection patterns from thalamic nuclei, especially from the subnuclei of the medial dorsal (MD) nucleus and the ventral thalamic nuclear group, make it possible to clearly differentiate three separate dorsal FC fields anterior to primary motor cortex: polar dPFC (dPFCpol), dPFC, and PMC. Based on the thalamic connectivity, there is a striking similarity of the ferret's dorsal FC fields with other species. This possible homology opens up new questions for future comparative neuroanatomical and functional studies.
journal_name
Brain Struct Functjournal_title
Brain structure & functionauthors
Radtke-Schuller S,Town SM,Yin P,Elgueda D,Schuller G,Bizley JK,Shamma SA,Fritz JBdoi
10.1007/s00429-020-02086-7subject
Has Abstractpub_date
2020-06-01 00:00:00pages
1643-1667issue
5eissn
1863-2653issn
1863-2661pii
10.1007/s00429-020-02086-7journal_volume
225pub_type
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