Cerebello-cerebral connectivity deficits in Friedreich ataxia.

abstract：:Brain connectivity in non-human primates (NHPs) has been mainly investigated using tracer techniques and functional connectivity studies. Data on structural connections are scarce and come from diffusion tensor imaging (DTI), since gross anatomical white matter dissection studies in the NHP are lacking. The current st...

journal_title：Brain structure & function

authors： Decramer T,Swinnen S,van Loon J,Janssen P,Theys T

更新日期：2018-11-01 00:00:00

abstract：:The hippocampal formation is important for higher brain functions such as spatial navigation and the consolidation of memory, and it contributes to abilities thought to be uniquely human, yet little is known about how the human hippocampal formation compares to that of our closest living relatives, the chimpanzees. To...

journal_title：Brain structure & function

authors： Rogers Flattery CN,Rosen RF,Farberg AS,Dooyema JM,Hof PR,Sherwood CC,Walker LC,Preuss TM

更新日期：2020-11-01 00:00:00

abstract：:The organization of the serotonergic system, one of the most important neurotransmitter systems in the brain, has been carefully analyzed in most vertebrate groups, and major shared characteristics have been described, although traits particular to each vertebrate class have also been found. The present study is the f...

journal_title：Brain structure & function

authors： López JM,González A

更新日期：2015-01-01 00:00:00

abstract：:Recently, neuroimaging-based Alzheimer's disease (AD) or mild cognitive impairment (MCI) diagnosis has attracted researchers in the field, due to the increasing prevalence of the diseases. Unfortunately, the unfavorable high-dimensional nature of neuroimaging data, but a limited small number of samples available, make...

journal_title：Brain structure & function

authors： Suk HI,Lee SW,Shen D,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2016-06-01 00:00:00

abstract：:Neonatal brain lesions cause deficits in structure and function of the cerebral cortex that sometimes are not fully expressed until adolescence. To better understand the onset and persistence of changes caused by postnatal day 7 (P7) ethanol treatment, we examined neocortical cell numbers, volume, surface area and thi...

journal_title：Brain structure & function

authors： Smiley JF,Bleiwas C,Masiello K,Petkova E,Betz J,Hui M,Wilson DA,Saito M

更新日期：2019-06-01 00:00:00

abstract：:One of the major challenges of functional magnetic resonance imaging (fMRI) data analysis is to develop simple and reliable methods to correlate brain regions with functionality. In this paper, we employ a detrending-based fractal method, called detrended fluctuation analysis (DFA), to identify brain activity from fMR...

journal_title：Brain structure & function

authors： Hu J,Lee JM,Gao J,White KD,Crosson B

更新日期：2008-02-01 00:00:00

abstract：:Matrix metalloproteinases (MMPs) are Zn(2+)-dependent endopeptidases considered to be essential for normal brain development and neuroplasticity by modulating extracellular matrix proteins, receptors, adhesion molecules, growth factors and cytoskeletal proteins. Specifically, MMP-3 has recently been implicated in syna...

journal_title：Brain structure & function

authors： Aerts J,Nys J,Moons L,Hu TT,Arckens L

更新日期：2015-09-01 00:00:00

abstract：:The cerebellum receives sensory signals from spinocerebellar (lower limbs) and dorsal column nuclei (upper limbs) mossy fibers. In the cerebellum, mossy fibers terminate in bands that are topographically aligned with stripes of Purkinje cells. While much is known about the molecular heterogeneity of Purkinje cell stri...

journal_title：Brain structure & function

authors： Gebre SA,Reeber SL,Sillitoe RV

更新日期：2012-04-01 00:00:00

abstract：:Despite robust sex differences in behavioral responses to drugs of abuse, relatively little is known about structural sex differences in synaptic connectivity of reward circuits such as in the nucleus accumbens (NAc). Previously, we showed that distal dendritic spine density on medium spiny neurons in the NAc is highe...

journal_title：Brain structure & function

authors： Wissman AM,May RM,Woolley CS

更新日期：2012-04-01 00:00:00

abstract：:The auditory midbrain (inferior colliculus, IC) plays an important role in sound processing, acting as hub for acoustic information extraction and for the implementation of fast audio-motor behaviors. IC neurons are topographically organized according to their sound frequency preference: dorsal IC regions encode low f...

journal_title：Brain structure & function

authors： González-Palomares E,López-Jury L,García-Rosales F,Hechavarria JC

更新日期：2021-01-01 00:00:00

abstract：:World-wide methamphetamine (meth) use is increasing at a rapid rate; therefore, it has become increasingly important to understand the synaptic changes and neural mechanisms affected by drug exposure. In rodents, 6-h access to contingent meth results in an escalation of drug intake and impaired cognitive sequelae typi...

journal_title：Brain structure & function

authors： Mishra D,Pena-Bravo JI,Leong KC,Lavin A,Reichel CM

更新日期：2017-07-01 00:00:00

abstract：:Glycoproteins are complex molecules of the cell surface and the extracellular matrix (ECM) playing a fundamental role in the migration, guidance and synapse formation of neurons. In the present study, the glycosylated protein composition and localization were investigated in the adult and developing CNS of an aquatic ...

journal_title：Brain structure & function

authors： Serfozo Z,Elekes K

更新日期：2009-12-01 00:00:00

abstract：:The extensive and increasing use of structural neuroimaging in the neurosciences rests on the assumption of an intimate relationship between structure and function in the human brain. However, few studies have examined the relationship between advanced magnetic resonance imaging (MRI) indices of cerebral structure and...

journal_title：Brain structure & function

authors： Elvsåshagen T,Moberget T,Bøen E,Hol PK,Malt UF,Andersson S,Westlye LT

更新日期：2015-03-01 00:00:00

abstract：:Diffusion tensor histology holds great promise for quantitative characterization of structural connectivity in mouse models of neurological and psychiatric conditions. There has been extensive study in both the clinical and preclinical domains on the complex tradeoffs between the spatial resolution, the number of samp...

journal_title：Brain structure & function

authors： Wang N,Anderson RJ,Badea A,Cofer G,Dibb R,Qi Y,Johnson GA

更新日期：2018-12-01 00:00:00

abstract：:Some of the known sex differences in white matter emerge during adolescence. Here, we replicate and extend our previous findings of sex differences in the structure of the corticospinal tract (Perrin et al. 2009; Hervé et al. 2009). In a large normative sample of adolescents, we observed age × sex interactions in the ...

journal_title：Brain structure & function

authors： Pangelinan MM,Leonard G,Perron M,Pike GB,Richer L,Veillette S,Pausova Z,Paus T

更新日期：2016-03-01 00:00:00

abstract：:The rostral nucleus of the solitary tract (rNST) receives gustatory input via chorda tympani (CT) afferents from the anterior two-thirds of the tongue and transmits it to higher brain regions. To help understand how the gustatory information is processed at the 1st relay nucleus of the brain stem, we investigated the ...

journal_title：Brain structure & function

authors： Park SK,Lee DS,Bae JY,Bae YC

更新日期：2016-03-01 00:00:00

abstract：:The cerebral cortex conveys major input to the granule cell layer of the cerebellar hemispheres by way of the pontine nuclei. Cerebrocortical projections terminate in multiple, widely distributed clusters in the pontine nuclei. This clustered organization is thought to provide the transition between the different orga...

journal_title：Brain structure & function

authors： Bolstad I,Leergaard TB,Bjaalie JG

更新日期：2007-07-01 00:00:00

abstract：:In the embryonic head of vertebrates, neurogenic and non-neurogenic ectodermal placodes arise from the panplacodal primordium. Whether and how growth processes of the ectodermal layer, changes in the transcriptional precursor cell profile, or positional changes among precursor cells contribute to interplacodal boundar...

journal_title：Brain structure & function

authors： Washausen S,Knabe W

更新日期：2013-05-01 00:00:00

abstract：:Exercise (physical activity) has been proposed as a treatment for drug addiction. In rodents, voluntary wheel running reduces cocaine and nicotine seeking during extinction, and reinstatement of cocaine seeking triggered by drug-cues. The purpose of this study was to examine the effects of chronic wheel running during...

journal_title：Brain structure & function

authors： Sobieraj JC,Kim A,Fannon MJ,Mandyam CD

更新日期：2016-01-01 00:00:00

abstract：:MRI was employed to follow the neurodegenerative foci and the localization of inflammatory cells by magnetically labeled CD4+ or CD8+ lymphocytes in the ischemia/reperfusion long-lived rats (9 and 13 months after 10 min of cardiac arrest). MRI of ischemic rats showed: (1) blood-brain barrier (BBB) leakage in the area ...

journal_title：Brain structure & function

authors： Sekeljic V,Bataveljic D,Stamenkovic S,Ułamek M,Jabłoński M,Radenovic L,Pluta R,Andjus PR

更新日期：2012-04-01 00:00:00

abstract：:Children born very preterm (VPT) at less than 32 weeks' gestational age (GA) are prone to disrupted white matter maturation and impaired cognitive development. The aims of the present study were to identify differences in white matter microstructure and connectivity of children born VPT compared to term-born children,...

journal_title：Brain structure & function

authors： Young JM,Vandewouw MM,Morgan BR,Smith ML,Sled JG,Taylor MJ

更新日期：2018-06-01 00:00:00

abstract：:Nitric oxide (NO) is well demonstrated to act as a neuronal messenger in neurotransmission in vertebrate animals. We are for the first time reporting nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d) and neuronal nitric oxide synthase (nNOS) in the Mauthner cells (MC) of the carp, Labeo rohita brain dur...

journal_title：Brain structure & function

authors： Palande NV,Biswas S,Jadhao AG

更新日期：2011-03-01 00:00:00

abstract：:Hippocampal atrophy and neuron loss are commonly found in Alzheimer's disease (AD). However, the underlying molecular mechanisms and the fate in the AD hippocampus of subpopulations of interneurons that express the calcium-binding proteins parvalbumin (PV) and calretinin (CR) has not yet been properly assessed. Using ...

journal_title：Brain structure & function

authors： Takahashi H,Brasnjevic I,Rutten BP,Van Der Kolk N,Perl DP,Bouras C,Steinbusch HW,Schmitz C,Hof PR,Dickstein DL

更新日期：2010-03-01 00:00:00

abstract：:The fornix is the primary efferent pathway of the hippocampus and plays a central role in memory circuitry. Diffusion tensor imaging has shown changes in the fornix with typical development and aging. Here, the fornix was investigated in 903 healthy young adult participants aged 22-36 years old from the high-spatial r...

journal_title：Brain structure & function

authors： Cahn AJ,Little G,Beaulieu C,Tétreault P

更新日期：2021-01-02 00:00:00

abstract：:Hox proteins are key regulators of animal development, providing positional identity and patterning information to cells along the rostrocaudal axis of the embryo. Although their embryonic expression and function are well characterized, their presence and biological importance in adulthood remains poorly investigated....

journal_title：Brain structure & function

authors： Hutlet B,Theys N,Coste C,Ahn MT,Doshishti-Agolli K,Lizen B,Gofflot F

更新日期：2016-04-01 00:00:00

abstract：:Sex differences are widespread across vertebrate nervous systems. Such differences are sometimes reflected in the neural substrate via neuroanatomical differences in brain region volume. One brain region that displays sex differences in its associated functions and pathologies is the striatum, including the caudate-pu...

journal_title：Brain structure & function

authors： Wong JE,Cao J,Dorris DM,Meitzen J

更新日期：2016-11-01 00:00:00

abstract：:Achievement motivation can be defined as a recurrent need to improve one's past performance. Despite previous functional imaging studies on motivation-related functional activation, the relationship between regional gray matter (rGM) morphology and achievement motivation has never been investigated. We used voxel-base...

journal_title：Brain structure & function

authors： Takeuchi H,Taki Y,Nouchi R,Sekiguchi A,Kotozaki Y,Miyauchi CM,Yokoyama R,Iizuka K,Hashizume H,Nakagawa S,Kunitoki K,Sassa Y,Kawashima R

更新日期：2014-01-01 00:00:00

abstract：:The developing cerebellum is extremely vulnerable to hypoxia which can damage the Purkinje neurons. We hypothesized that this might be mediated by tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) derived from activated microglia as in other brain areas. One-day-old rats were subjected to hypoxia following, w...

journal_title：Brain structure & function

authors： Kaur C,Sivakumar V,Zou Z,Ling EA

更新日期：2014-01-01 00:00:00

abstract：:The primary systems framework has been used to relate behavioural performance across many different language activities to the status of core underpinning domain-general cognitive systems. This study provided the first quantitative investigation of this account at both behavioural and neural levels in a group of patie...

journal_title：Brain structure & function

authors： Woollams AM,Halai A,Lambon Ralph MA

更新日期：2018-11-01 00:00:00

abstract：:Evidence suggests that extracellular matrix molecules of perivascular basal laminae help orchestrate the molecular assemblies at the gliovascular interface. Specifically, laminin and agrin are thought to tether the dystrophin-associated protein (DAP) complex to the astrocytic basal lamina. This complex includes α-synt...

journal_title：Brain structure & function

authors： Hoddevik EH,Rao SB,Zahl S,Boldt HB,Ottersen OP,Amiry-Moghaddam M

更新日期：2020-03-01 00:00:00