Systematic expression analysis of Hox genes at adulthood reveals novel patterns in the central nervous system.

abstract：:Children born very preterm (VPT) at less than 32 weeks' gestational age (GA) are prone to disrupted white matter maturation and impaired cognitive development. The aims of the present study were to identify differences in white matter microstructure and connectivity of children born VPT compared to term-born children,...

journal_title：Brain structure & function

authors： Young JM,Vandewouw MM,Morgan BR,Smith ML,Sled JG,Taylor MJ

更新日期：2018-06-01 00:00:00

abstract：:Rho-associated protein kinases (ROCK) 1 and 2 are attractive drug targets for a range of neurologic disorders; however, a critical barrier to ROCK-based therapeutics is ambiguity over whether there are isoform-specific roles for ROCKs in neuronal structural plasticity. Here, we used a genetics approach to address this...

journal_title：Brain structure & function

authors： Greathouse KM,Boros BD,Deslauriers JF,Henderson BW,Curtis KA,Gentry EG,Herskowitz JH

更新日期：2018-12-01 00:00:00

abstract：:Accumulating evidence suggests that besides its function in early facial feature processing, the role of the right occipital face area (rOFA) extends to higher level, image-independent processing. Recent studies hint at the possibility that the activity of this region can be modulated by semantic information as well. ...

journal_title：Brain structure & function

authors： Ambrus GG,Amado C,Krohn L,Kovács G

更新日期：2019-01-01 00:00:00

abstract：:In recent years, the demonstration that structural changes can occur in the human brain beyond those associated with development, ageing and neuropathology has revealed a new approach to studying the neural basis of behaviour. In this review paper, we focus on structural imaging studies of language that have utilised ...

journal_title：Brain structure & function

authors： Richardson FM,Price CJ

更新日期：2009-10-01 00:00:00

abstract：:Sex differences are widespread across vertebrate nervous systems. Such differences are sometimes reflected in the neural substrate via neuroanatomical differences in brain region volume. One brain region that displays sex differences in its associated functions and pathologies is the striatum, including the caudate-pu...

journal_title：Brain structure & function

authors： Wong JE,Cao J,Dorris DM,Meitzen J

更新日期：2016-11-01 00:00:00

abstract：:How can the components of visual comprehension be characterized as brain activity? Making sense of a dynamic visual world involves perceiving streams of activity as discrete units such as eating breakfast or walking the dog. In order to parse activity into distinct events, the brain relies on both the perceptual (bott...

journal_title：Brain structure & function

authors： Hanson SJ,Hanson C,Halchenko Y,Matsuka T,Zaimi A

更新日期：2007-12-01 00:00:00

abstract：:The ventral striatum (VS) is of particular interest in the study of neuropsychiatric disorders. In this study, performed on non-human primates, we associated local perturbation with monosynaptic axonal tracer injection into medial, central and lateral VS to characterize anatomo-functional circuits underlying the respe...

journal_title：Brain structure & function

authors： Sgambato-Faure V,Worbe Y,Epinat J,Féger J,Tremblay L

更新日期：2016-01-01 00:00:00

abstract：:To better understand information transfer along the hippocampal pathways and its plasticity, here we studied the antidromic responses of the dentate gyrus (DG) and CA3 to activation of the mossy fibers and Schaffer collaterals, respectively, in hippocampal slices from naïve and epileptic rats. We applied trains of 600...

journal_title：Brain structure & function

authors： Franco LM,Beltrán JQ,Tapia JA,Ortiz F,Manjarrez E,Gutiérrez R

更新日期：2016-05-01 00:00:00

abstract：:The interthalamic adhesion (ITA) is an understudied neuroanatomical structure that forms a bridge of tissue connecting the thalamus of each hemisphere across the midline whose functional significance remains largely unknown. The likelihood of ITA absence has been reported in some studies to be increased in males, but ...

journal_title：Brain structure & function

authors： Damle NR,Ikuta T,John M,Peters BD,DeRosse P,Malhotra AK,Szeszko PR

更新日期：2017-07-01 00:00:00

abstract：:Anterior cingulate cortex (ACC) input to the claustrum is required for top-down cognitive control of action. By virtue of its widespread cortical connectivity, the claustrum is anatomically situated to process and broadcast top-down signals from ACC to downstream cortices. To gain a deeper understanding of claustrum p...

journal_title：Brain structure & function

authors： White MG,Mathur BN

更新日期：2018-12-01 00:00:00

abstract：:The insula is a brain structure implicated in disparate cognitive, affective, and regulatory functions, including interoceptive awareness, emotional responses, and empathic processes. While classically considered a limbic region, recent evidence from network analysis suggests a critical role for the insula, particular...

journal_title：Brain structure & function

authors： Menon V,Uddin LQ

更新日期：2010-06-01 00:00:00

abstract：:Hippocampal atrophy and neuron loss are commonly found in Alzheimer's disease (AD). However, the underlying molecular mechanisms and the fate in the AD hippocampus of subpopulations of interneurons that express the calcium-binding proteins parvalbumin (PV) and calretinin (CR) has not yet been properly assessed. Using ...

journal_title：Brain structure & function

authors： Takahashi H,Brasnjevic I,Rutten BP,Van Der Kolk N,Perl DP,Bouras C,Steinbusch HW,Schmitz C,Hof PR,Dickstein DL

更新日期：2010-03-01 00:00:00

abstract：:Recent research has shown that at least two tryptophan hydroxylase (Tph) genes are present in gnathostome vertebrates, but it is not known when the duplication of the ancestral Tph gene took place during evolution. By their position as an out-group of gnathostomes, lampreys (agnathans) are key models to understand mo...

journal_title：Brain structure & function

authors： Cornide-Petronio ME,Anadón R,Rodicio MC,Barreiro-Iglesias A

更新日期：2013-03-01 00:00:00

abstract：:Glucose metabolism produces, by oxidative phosphorylation, more than 15 times the amount of energy generated by aerobic glycolysis. Nonetheless, aerobic glycolysis remains a prevalent metabolic pathway in the brain. Here we review evidence suggesting that this pathway contributes essential molecules to the biomass of ...

journal_title：Brain structure & function

authors： Bauernfeind AL,Barks SK,Duka T,Grossman LI,Hof PR,Sherwood CC

更新日期：2014-07-01 00:00:00

abstract：:The acoustic radiation is a compact bundle of fibers conveying auditory information from the medial geniculate nucleus of the thalamus to the auditory cortex. Topographical knowledge of this bundle in primates is scarce and in vivo diffusion-based tractography reconstructions in humans remains challenging, especially ...

journal_title：Brain structure & function

authors： Maffei C,Jovicich J,De Benedictis A,Corsini F,Barbareschi M,Chioffi F,Sarubbo S

更新日期：2018-01-01 00:00:00

abstract：:The 30-amino acid peptide Y-P30, generated from the N-terminus of the human dermcidin precursor protein, has been found to promote neuronal survival, cell migration and neurite outgrowth by enhancing the interaction of pleiotrophin and syndecan-3. We now show that Y-P30 activates Src kinase and extracellular signal-re...

journal_title：Brain structure & function

authors： Neumann JR,Dash-Wagh S,Jüngling K,Tsai T,Meschkat M,Räk A,Schönfelder S,Riedel C,Hamad MI,Wiese S,Pape HC,Gottmann K,Kreutz MR,Wahle P

更新日期：2015-07-01 00:00:00

abstract：:Several studies have begun to demonstrate that contextual memories constitute an important mechanism to guide our attention. Although there is general consensus that the hippocampus is involved in the encoding of contextual memories, it is controversial whether this structure can support implicit forms of contextual m...

journal_title：Brain structure & function

authors： Rosero MA,Winkelmann T,Pohlack S,Cavalli J,Nees F,Flor H

更新日期：2019-07-01 00:00:00

abstract：:The functional specificity of brain areas is diminished with age and accompanied by the recruitment of additional brain regions in healthy older adults. This process has repeatedly been demonstrated within distinct functional domains, in particular the visual system. However, it is yet unclear, whether this phenomenon...

journal_title：Brain structure & function

authors： Roski C,Caspers S,Lux S,Hoffstaedter F,Bergs R,Amunts K,Eickhoff SB

更新日期：2014-03-01 00:00:00

abstract：:The human visual system is capable of processing visual information from fovea to the far peripheral visual field. Recent fMRI studies have shown a full and detailed retinotopic map in area prostriata, located ventro-dorsally and anterior to the calcarine sulcus along the parieto-occipital sulcus with strong preferenc...

journal_title：Brain structure & function

authors： Kurzawski JW,Mikellidou K,Morrone MC,Pestilli F

更新日期：2020-07-01 00:00:00

abstract：:In the mammalian auditory system, the medial nucleus of the trapezoid body and the lateral superior olive (MNTB-LSO system) contribute to binaural intensity processing and lateralization. Localization precision varies with the sound frequencies. As recency of common ancestry with human beings increases, primates have ...

journal_title：Brain structure & function

authors： Hilbig H,Beil B,Hilbig H,Call J,Bidmon HJ

更新日期：2009-09-01 00:00:00

abstract：:The characterization of neuronal properties is a necessary first step toward understanding how the ventrolateral preoptic nucleus (VLPO) neuronal network regulates slow-wave sleep (SWS). Indeed, the electrophysiological heterogeneity of VLPO neurons suggests the existence of subtypes that could differently contribute ...

journal_title：Brain structure & function

authors： Dubourget R,Sangare A,Geoffroy H,Gallopin T,Rancillac A

更新日期：2017-04-01 00:00:00

abstract：:To establish the link between structure and function of any large area of the neocortex, it is helpful to identify its principles of organisation. One way to establish such principles is to investigate how differences in whole-brain connectivity are structured across the area. Here, we use Laplacian eigenmaps on diffu...

journal_title：Brain structure & function

authors： Blazquez Freches G,Haak KV,Bryant KL,Schurz M,Beckmann CF,Mars RB

更新日期：2020-05-01 00:00:00

abstract：:Higher cognitive processes and emotional regulation depend on densely interconnected telencephalic and limbic areas. Central structures of this cortico-limbic network are ventral hippocampus (vHC), medial prefrontal cortex (PFC), basolateral amygdala (BLA) and nucleus accumbens (NAC). Human and animal studies have rev...

journal_title：Brain structure & function

authors： Khastkhodaei Z,Muthuraman M,Yang JW,Groppa S,Luhmann HJ

更新日期：2021-01-13 00:00:00

abstract：:Hyperpolarization-activated cyclic nucleotide-gated cation (HCN) channels have important functions in controlling neuronal excitability and generating rhythmic oscillatory activity. The role of tetratricopeptide repeat-containing Rab8b-interacting protein (TRIP8b) in regulation of hyperpolarization-activated inward cu...

journal_title：Brain structure & function

authors： Zobeiri M,Chaudhary R,Datunashvili M,Heuermann RJ,Lüttjohann A,Narayanan V,Balfanz S,Meuth P,Chetkovich DM,Pape HC,Baumann A,van Luijtelaar G,Budde T

更新日期：2018-04-01 00:00:00

abstract：:Forebrain serotonin relevant for many psychological disorders arises in the hindbrain, primarily within the dorsal and median raphe nuclei (DR and MR). These nuclei are heterogeneous, containing several distinct groups of serotonin neurons. Here, new insight into the afferent and efferent connectivity of these areas i...

journal_title：Brain structure & function

authors： Commons KG

更新日期：2016-09-01 00:00:00

abstract：:The medial septum and diagonal band of Broca (MSDB) influence hippocampal function through cholinergic, GABAergic, and glutamatergic septohippocampal neurons. Non-selective damage of the MSDB or intraseptal scopolamine impairs classical conditioning of the eyeblink response (CCER). Scopolamine preferentially inhibits ...

journal_title：Brain structure & function

authors： Roland JJ,Janke KL,Servatius RJ,Pang KC

更新日期：2014-07-01 00:00:00

abstract：:The tegmental pedunculopontine nucleus (PPN) is a basal ganglia-related structure that has recently gained renewed interest as a potential surgical target for the treatment of several aspects of Parkinson's disease. However, the underlying anatomical substrates sustaining the choice of the PPN nucleus as a surgical ca...

journal_title：Brain structure & function

authors： Barroso-Chinea P,Rico AJ,Conte-Perales L,Gómez-Bautista V,Luquin N,Sierra S,Roda E,Lanciego JL

更新日期：2011-11-01 00:00:00

abstract：:AMIGO2, or amphoterin-induced gene and ORF (open reading frame) 2, belongs to the leucine-rich repeats and immunoglobulin superfamilies. The protein is a downstream target of calcium-dependent survival signals and, therefore, promotes neuronal survival. Here, we describe the mRNA distribution pattern of AMIGO2 through...

journal_title：Brain structure & function

authors： Laeremans A,Nys J,Luyten W,D'Hooge R,Paulussen M,Arckens L

更新日期：2013-01-01 00:00:00

abstract：:Glycoproteins are complex molecules of the cell surface and the extracellular matrix (ECM) playing a fundamental role in the migration, guidance and synapse formation of neurons. In the present study, the glycosylated protein composition and localization were investigated in the adult and developing CNS of an aquatic ...

journal_title：Brain structure & function

authors： Serfozo Z,Elekes K

更新日期：2009-12-01 00:00:00

abstract：:Goal-directed behavior has been shown to be affected by consciously and subliminally induced conflicts. Both types of conflict conjointly modulate behavioral performance, but the underlying neuronal mechanisms have remained unclear. While cognitive control is linked to oscillations in the theta frequency band, there a...

journal_title：Brain structure & function

authors： Bensmann W,Zink N,Mückschel M,Beste C,Stock AK

更新日期：2019-06-01 00:00:00