AMIGO2 mRNA expression in hippocampal CA2 and CA3a.

Abstract:

:AMIGO2, or amphoterin-induced gene and ORF (open reading frame) 2, belongs to the leucine-rich repeats and immunoglobulin superfamilies. The protein is a downstream target of calcium-dependent survival signals and, therefore, promotes neuronal survival. Here, we describe the mRNA distribution pattern of AMIGO2 throughout the mouse brain with special emphasis on the hippocampus. In the Ammon's horn, a detailed comparison between the subregional mRNA expression patterns of AMIGO2 and Pcp4 (Purkinje cell protein 4)--a known molecular marker of hippocampal CA2 (Cornu Ammonis 2)--revealed a prominent AMIGO2 mRNA expression level in both the CA2 and the CA3a (Cornu Ammonis 3a) subregion of the dorsal and ventral hippocampus. Since this CA2/CA3a region is particularly resistant to neuronal injury and neurotoxicity [Stanfield and Cowan (Brain Res 309(2):299–307 1984); Sloviter (J Comp Neurol 280(2):183–196 1989); Leranth and Ribak (Exp Brain Res 85(1):129–136 1991); Young and Dragunow (Exp Neurol 133(2):125–137 1995); Ochiishi et al. (Neurosci 93(3):955–967 1999)], we suggest that the expression pattern of AMIGO2 indeed fits with its involvement in neuroprotection.

journal_name

Brain Struct Funct

authors

Laeremans A,Nys J,Luyten W,D'Hooge R,Paulussen M,Arckens L

doi

10.1007/s00429-012-0387-4

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

123-30

issue

1

eissn

1863-2653

issn

1863-2661

journal_volume

218

pub_type

杂志文章
  • High expression of retinoic acid receptors and synthetic enzymes in the human hippocampus.

    abstract::Retinoic acid, the active form of the nutrient vitamin A, regulates several facets of neuronal plasticity in the hippocampus, including neurogenesis and synaptic strength, acting via specific retinoic acid receptors (RARs). Essential for conversion of vitamin A to retinoic acid is the enzyme retinaldehyde dehydrogenas...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-011-0359-0

    authors: Fragoso YD,Shearer KD,Sementilli A,de Carvalho LV,McCaffery PJ

    更新日期:2012-04-01 00:00:00

  • Vertex- and atlas-based comparisons in measures of cortical thickness, gyrification and white matter volume between humans and chimpanzees.

    abstract::What changes in cortical organisation characterise global and localised variation between humans and chimpanzees remains a topic of considerable interest in evolutionary neuroscience. Here, we examined regional variation in cortical thickness, gyrification and white matter in samples of human and chimpanzee brains. Bo...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-016-1213-1

    authors: Hopkins WD,Li X,Crow T,Roberts N

    更新日期:2017-01-01 00:00:00

  • Deep sparse multi-task learning for feature selection in Alzheimer's disease diagnosis.

    abstract::Recently, neuroimaging-based Alzheimer's disease (AD) or mild cognitive impairment (MCI) diagnosis has attracted researchers in the field, due to the increasing prevalence of the diseases. Unfortunately, the unfavorable high-dimensional nature of neuroimaging data, but a limited small number of samples available, make...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-015-1059-y

    authors: Suk HI,Lee SW,Shen D,Alzheimer’s Disease Neuroimaging Initiative.

    更新日期:2016-06-01 00:00:00

  • Rapid immunostaining method for three-dimensional volume imaging of biological tissues by magnetic force-induced focusing of the electric field.

    abstract::Recent surges in tissue clearing technology have greatly advanced 3-dimensional (3D) volume imaging. Cleared tissues need to be stained with fluorescence probes for imaging but the current staining methods are too laborious and inefficient for thick 3D samples, which impedes the broad application of clearing technolog...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-020-02160-0

    authors: Na M,Kim K,Lim HR,Ha CM,Chang S

    更新日期:2021-01-01 00:00:00

  • Orienting movements in area 9 identified by long-train ICMS.

    abstract::The effect of intracortical microstimulation has been studied in several cortical areas from motor to sensory areas. The frontal pole has received particular attention, and several microstimulation studies have been conducted in the frontal eye field, supplementary eye field, and the premotor ear-eye field, but no mic...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-013-0682-8

    authors: Lanzilotto M,Perciavalle V,Lucchetti C

    更新日期:2015-03-01 00:00:00

  • The surface area of early visual cortex predicts the amplitude of the visual evoked potential.

    abstract::The extensive and increasing use of structural neuroimaging in the neurosciences rests on the assumption of an intimate relationship between structure and function in the human brain. However, few studies have examined the relationship between advanced magnetic resonance imaging (MRI) indices of cerebral structure and...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-013-0703-7

    authors: Elvsåshagen T,Moberget T,Bøen E,Hol PK,Malt UF,Andersson S,Westlye LT

    更新日期:2015-03-01 00:00:00

  • Vesicular glutamate transporter 1 (VGLUT1)- and VGLUT2-immunopositive axon terminals on the rat jaw-closing and jaw-opening motoneurons.

    abstract::To provide information on the glutamatergic synapses on the trigeminal motoneurons, which may be important for understanding the mechanism of control of jaw movements, we investigated the distribution of vesicular glutamate transporter (VGLUT)1-immunopositive (+) and VGLUT2 + axon terminals (boutons) on the rat jaw-cl...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-018-1636-y

    authors: Park SK,Ko SJ,Paik SK,Rah JC,Lee KJ,Bae YC

    更新日期:2018-06-01 00:00:00

  • Topography of the human acoustic radiation as revealed by ex vivo fibers micro-dissection and in vivo diffusion-based tractography.

    abstract::The acoustic radiation is a compact bundle of fibers conveying auditory information from the medial geniculate nucleus of the thalamus to the auditory cortex. Topographical knowledge of this bundle in primates is scarce and in vivo diffusion-based tractography reconstructions in humans remains challenging, especially ...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-017-1471-6

    authors: Maffei C,Jovicich J,De Benedictis A,Corsini F,Barbareschi M,Chioffi F,Sarubbo S

    更新日期:2018-01-01 00:00:00

  • Comparative analysis of the serotonergic systems in the CNS of two lungfishes, Protopterus dolloi and Neoceratodus forsteri.

    abstract::The organization of the serotonergic system, one of the most important neurotransmitter systems in the brain, has been carefully analyzed in most vertebrate groups, and major shared characteristics have been described, although traits particular to each vertebrate class have also been found. The present study is the f...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-013-0661-0

    authors: López JM,González A

    更新日期:2015-01-01 00:00:00

  • Early-life sleep deprivation persistently depresses melatonin production and bio-energetics of the pineal gland: potential implications for the development of metabolic deficiency.

    abstract::Early-life sleep deprivation (ESD) is a serious condition with severe metabolic sequelae. The pineal hormone melatonin plays an important role in homeostatic regulation of metabolic function. Considering norepinephrine-mediated Ca(2+) influx and subsequent protein kinase A (PKA) activation is responsible for downstrea...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-014-0716-x

    authors: Chen LY,Tiong C,Tsai CH,Liao WC,Yang SF,Youn SC,Mai FD,Chang HM

    更新日期:2015-03-01 00:00:00

  • Blood total antioxidant status is associated with cortical glucose uptake and factors related to accelerated aging.

    abstract::Identifying cerebral vulnerability in late life is of paramount importance to prevent pathological trajectories of aging before the onset of symptoms. Considerable evidence suggests that impaired antioxidant mechanisms are a fingerprint of aging-related conditions, but there is a lack of human research linking total a...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-020-02039-0

    authors: Palomar-Bonet M,Atienza M,Cantero JL

    更新日期:2020-03-01 00:00:00

  • The ontogeny of Mauthner cells in the brain of Labeo rohita as revealed by NADPH-d and nNOS immunohistochemistry.

    abstract::Nitric oxide (NO) is well demonstrated to act as a neuronal messenger in neurotransmission in vertebrate animals. We are for the first time reporting nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d) and neuronal nitric oxide synthase (nNOS) in the Mauthner cells (MC) of the carp, Labeo rohita brain dur...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-010-0292-7

    authors: Palande NV,Biswas S,Jadhao AG

    更新日期:2011-03-01 00:00:00

  • Branching of individual somatosensory cerebropontine axons in rat: evidence of divergence.

    abstract::The cerebral cortex conveys major input to the granule cell layer of the cerebellar hemispheres by way of the pontine nuclei. Cerebrocortical projections terminate in multiple, widely distributed clusters in the pontine nuclei. This clustered organization is thought to provide the transition between the different orga...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-007-0145-1

    authors: Bolstad I,Leergaard TB,Bjaalie JG

    更新日期:2007-07-01 00:00:00

  • Effects of neonatal ethanol on cerebral cortex development through adolescence.

    abstract::Neonatal brain lesions cause deficits in structure and function of the cerebral cortex that sometimes are not fully expressed until adolescence. To better understand the onset and persistence of changes caused by postnatal day 7 (P7) ethanol treatment, we examined neocortical cell numbers, volume, surface area and thi...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-019-01881-1

    authors: Smiley JF,Bleiwas C,Masiello K,Petkova E,Betz J,Hui M,Wilson DA,Saito M

    更新日期:2019-06-01 00:00:00

  • Ghrelin receptor signaling targets segregated clusters of neurons within the nucleus of the solitary tract.

    abstract::Ghrelin is a stomach-derived hormone that regulates a variety of biological functions such as food intake, gastrointestinal function and blood glucose metabolism, among others. Ghrelin acts via the growth hormone secretagogue receptor (GHSR), a G-protein-coupled receptor located in key brain areas that mediate specifi...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-018-1682-5

    authors: Cornejo MP,De Francesco PN,García Romero G,Portiansky EL,Zigman JM,Reynaldo M,Perello M

    更新日期:2018-09-01 00:00:00

  • A 3-dimensional digital atlas of the ascending sensory and the descending motor systems in the pigeon brain.

    abstract::Pigeons are classic animal models for learning, memory, and cognition. The majority of the current understanding about avian neurobiology outside of the domain of the song system has been established using pigeons. Since MRI represents an increasingly relevant tool for comparative neuroscience, a 3-dimensional MRI-bas...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-012-0400-y

    authors: Güntürkün O,Verhoye M,De Groof G,Van der Linden A

    更新日期:2013-01-01 00:00:00

  • A volumetric study of the corpus callosum in 20s and 40s Korean people.

    abstract::The purpose of this study was to measure the average corpus callosum volume of normal Koreans (aged in their 20s or 40s) and to analyze the effects of gender, age, and body parameters, such as height and weight on corpus callosum size. Magnetic resonance brain images were recorded for 68 people in their 20s (29 men, 3...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-009-0209-5

    authors: Lee BY,Sohn JH,Choi MH,Lee SJ,Kim HS,Yang JW,Choi JS,Kim HS,Yi JH,Tack GR,Chung SC

    更新日期:2009-09-01 00:00:00

  • Claustrum circuit components for top-down input processing and cortical broadcast.

    abstract::Anterior cingulate cortex (ACC) input to the claustrum is required for top-down cognitive control of action. By virtue of its widespread cortical connectivity, the claustrum is anatomically situated to process and broadcast top-down signals from ACC to downstream cortices. To gain a deeper understanding of claustrum p...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-018-1731-0

    authors: White MG,Mathur BN

    更新日期:2018-12-01 00:00:00

  • Age-related differences in task goal processing strategies during action cascading.

    abstract::We are often faced with situations requiring the execution of a coordinated cascade of different actions to achieve a goal, but we can apply different strategies to do so. Until now, these different action cascading strategies have, however, not been examined with respect to possible effects of aging. We tackled this ...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-015-1071-2

    authors: Stock AK,Gohil K,Beste C

    更新日期:2016-06-01 00:00:00

  • Modifications of perineuronal nets and remodelling of excitatory and inhibitory afferents during vestibular compensation in the adult mouse.

    abstract::Perineuronal nets (PNNs) are aggregates of extracellular matrix molecules surrounding several types of neurons in the adult CNS, which contribute to stabilising neuronal connections. Interestingly, a reduction of PNN number and staining intensity has been observed in conditions associated with plasticity in the adult ...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-015-1095-7

    authors: Faralli A,Dagna F,Albera A,Bekku Y,Oohashi T,Albera R,Rossi F,Carulli D

    更新日期:2016-07-01 00:00:00

  • Decreasing predictability of visual motion enhances feed-forward processing in visual cortex when stimuli are behaviorally relevant.

    abstract::Recent views of information processing in the (human) brain emphasize the hierarchical structure of the central nervous system, which is assumed to form the basis of a functional hierarchy. Hierarchical predictive processing refers to the notion that higher levels try to predict activity in lower areas, while lower le...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-016-1251-8

    authors: Kellermann T,Scholle R,Schneider F,Habel U

    更新日期:2017-03-01 00:00:00

  • Ultrastructural analysis of sex differences in nucleus accumbens synaptic connectivity.

    abstract::Despite robust sex differences in behavioral responses to drugs of abuse, relatively little is known about structural sex differences in synaptic connectivity of reward circuits such as in the nucleus accumbens (NAc). Previously, we showed that distal dendritic spine density on medium spiny neurons in the NAc is highe...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-011-0353-6

    authors: Wissman AM,May RM,Woolley CS

    更新日期:2012-04-01 00:00:00

  • Thalamic alterations in preterm neonates and their relation to ventral striatum disturbances revealed by a combined shape and pose analysis.

    abstract::Finding the neuroanatomical correlates of prematurity is vital to understanding which structures are affected, and to designing efficient prevention and treatment strategies. Converging results reveal that thalamic abnormalities are important indicators of prematurity. However, little is known about the localization o...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-014-0921-7

    authors: Lao Y,Wang Y,Shi J,Ceschin R,Nelson MD,Panigrahy A,Leporé N

    更新日期:2016-01-01 00:00:00

  • Melatonin receptors: distribution in mammalian brain and their respective putative functions.

    abstract::Melatonin, through its different receptors, has pleiotropic functions in mammalian brain. Melatonin is secreted mainly by the pineal gland and exerts its effects via receptor-mediated and non-receptor-mediated actions. With recent advancement in neuroanatomical mapping, we may now understand better the localizations o...

    journal_title:Brain structure & function

    pub_type: 杂志文章,评审

    doi:10.1007/s00429-017-1439-6

    authors: Ng KY,Leong MK,Liang H,Paxinos G

    更新日期:2017-09-01 00:00:00

  • Synaptic mechanisms underlying the intense firing of neocortical layer 5B pyramidal neurons in response to cortico-cortical inputs.

    abstract::In the neocortex, large layer 5B pyramidal neurons implement a high-density firing code. In contrast, other subtypes of pyramidal neurons, including those in layer 2/3, are functionally characterized by their sparse firing rate. Here, we investigate the synaptic basis of this behavior by comparing the properties of th...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-019-01842-8

    authors: Sempere-Ferràndez A,Martínez S,Geijo-Barrientos E

    更新日期:2019-05-01 00:00:00

  • Genetic sex and the volumes of the caudate-putamen, nucleus accumbens core and shell: original data and a review.

    abstract::Sex differences are widespread across vertebrate nervous systems. Such differences are sometimes reflected in the neural substrate via neuroanatomical differences in brain region volume. One brain region that displays sex differences in its associated functions and pathologies is the striatum, including the caudate-pu...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-015-1158-9

    authors: Wong JE,Cao J,Dorris DM,Meitzen J

    更新日期:2016-11-01 00:00:00

  • Spatiotemporal expression patterns of Pax6 in the brain of embryonic, newborn, and adult mice.

    abstract::The transcription factor Pax6 has been reported to specify neural progenitor cell fates during development and maintain neuronal commitments in the adult. The spatiotemporal patterns of Pax6 expression were examined in sagittal and horizontal sections of the embryonic, postnatal, and adult brains using immunohistochem...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-012-0397-2

    authors: Duan D,Fu Y,Paxinos G,Watson C

    更新日期:2013-03-01 00:00:00

  • Enhanced representation of natural sound sequences in the ventral auditory midbrain.

    abstract::The auditory midbrain (inferior colliculus, IC) plays an important role in sound processing, acting as hub for acoustic information extraction and for the implementation of fast audio-motor behaviors. IC neurons are topographically organized according to their sound frequency preference: dorsal IC regions encode low f...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-020-02188-2

    authors: González-Palomares E,López-Jury L,García-Rosales F,Hechavarria JC

    更新日期:2021-01-01 00:00:00

  • Reduced resting-state functional connectivity of the basolateral amygdala to the medial prefrontal cortex in preweaning rats exposed to chronic early-life stress.

    abstract::Early-life stress (ELS) exposure has long-term consequences for both brain structure and function and impacts cognitive and emotional behavior. The basolateral amygdala (BLA) plays an important role in anxiety and fear conditioning through its extensive anatomical and functional connections, in particular to the media...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-018-1720-3

    authors: Guadagno A,Kang MS,Devenyi GA,Mathieu AP,Rosa-Neto P,Chakravarty M,Walker CD

    更新日期:2018-11-01 00:00:00

  • Quantitative mapping of the local and extrinsic sources of GABA and Reelin to the layer Ia neuropil in the adult rat neocortex.

    abstract::Inputs to apical dendritic tufts have been considered to be crucial for associative learning, attention and similar ''feedback'' interactions and are located in neocortical layer Ia. Excitatory thalamic projections to apical tufts in layer Ia have been well characterized and their role in the cortical circuit has been...

    journal_title:Brain structure & function

    pub_type: 杂志文章

    doi:10.1007/s00429-013-0591-x

    authors: Ramos-Moreno T,Clascá F

    更新日期:2014-09-01 00:00:00