Metabolomics and neuroanatomical evaluation of post-mortem changes in the hippocampus.

abstract：:The primary systems framework has been used to relate behavioural performance across many different language activities to the status of core underpinning domain-general cognitive systems. This study provided the first quantitative investigation of this account at both behavioural and neural levels in a group of patie...

journal_title：Brain structure & function

authors： Woollams AM,Halai A,Lambon Ralph MA

更新日期：2018-11-01 00:00:00

abstract：:Previous diffusion tensor imaging (DTI) studies have shown that various factors can affect white matter (WM) tract diffusivity. The aim of the present study was to investigate the effects of childhood adversity (CA), age and gender on WM diffusivity in tracts that are thought to be involved in emotional regulation in ...

journal_title：Brain structure & function

authors： Ugwu ID,Amico F,Carballedo A,Fagan AJ,Frodl T

更新日期：2015-07-01 00:00:00

abstract：:Chaining or cascading of different actions and responses is necessary to accomplish a goal. Yet, little is known about the functional neuroanatomical-electrophysiological mechanisms mediating these processes. Computational models suggest that medium spiny neurons (MSNs) play an important role in action cascading, but ...

journal_title：Brain structure & function

authors： Beste C,Saft C

更新日期：2015-01-01 00:00:00

abstract：:In the embryonic head of vertebrates, neurogenic and non-neurogenic ectodermal placodes arise from the panplacodal primordium. Whether and how growth processes of the ectodermal layer, changes in the transcriptional precursor cell profile, or positional changes among precursor cells contribute to interplacodal boundar...

journal_title：Brain structure & function

authors： Washausen S,Knabe W

更新日期：2013-05-01 00:00:00

abstract：:The structure of neurons in the central auditory system is vulnerable to various kinds of acoustic exposures during the critical postnatal developmental period. Here we explored long-term effects of exposure to an acoustically enriched environment (AEE) during the third and fourth weeks of the postnatal period in rat ...

journal_title：Brain structure & function

authors： Svobodová Burianová J,Syka J

更新日期：2020-09-01 00:00:00

abstract：:Proprioceptive signals from body muscles have historically been considered to project to the rostrodorsal shell of the ventrobasal thalamic complex [the ventral posterolateral nucleus (VPL) and ventral posteromedial nucleus (VPM)]. However, we have recently found that proprioception from rat jaw-closing muscle spindle...

journal_title：Brain structure & function

authors： Uemura Y,Haque T,Sato F,Tsutsumi Y,Ohara H,Oka A,Furuta T,Bae YC,Yamashiro T,Tachibana Y,Yoshida A

更新日期：2020-09-01 00:00:00

abstract：:Reduction in the amount of brain-derived neurotrophic factor (BDNF) in corticostriatal afferents is thought to contribute to the vulnerability of medium spiny striatal neurons in Huntington's disease. In young Bdnf heterozygous ((+/-)) mice, striatal medium spiny neurons (MSNs) express less preprodynorphin (PPD), prep...

journal_title：Brain structure & function

authors： Saylor AJ,McGinty JF

更新日期：2010-08-01 00:00:00

abstract：:The pedunculopontine nucleus (PPN) is composed of neurons with different connectivity patterns that express different neurochemical markers, display distinct firing characteristics and are topographically organized in functional domains across its rostro-caudal axis. Previous reports have shown that the caudal region ...

journal_title：Brain structure & function

authors： Martinez-Gonzalez C,van Andel J,Bolam JP,Mena-Segovia J

更新日期：2014-07-01 00:00:00

abstract：:The bulk of brain energy expenditure is allocated for maintenance of perpetual intrinsic activity of neurons and neural circuits. Long-term electrophysiological and neuroimaging studies in anesthetized and behaving animals show, however, that the great majority of nerve cells in the intact brain do not fire action pot...

journal_title：Brain structure & function

authors： Ovsepian SV

更新日期：2019-04-01 00:00:00

abstract：:During the development of the central nervous system, the immature neurons suffer different migration processes. It is well known that Nkx2.1-positive ventricular layer give rise to critical tangential migrations into different regions of the developing forebrain. Our aim was to study this phenomenon in the hypothalam...

journal_title：Brain structure & function

authors： Murcia-Ramón R,Company V,Juárez-Leal I,Andreu-Cervera A,Almagro-García F,Martínez S,Echevarría D,Puelles E

更新日期：2020-12-01 00:00:00

abstract：:There is limited information on the role of GABA type A receptors (GABAARs) containing α1, α5 and γ2 subunits in learning and memory. Here, we assessed the possible role of such receptors in spatial learning using the multiple T-maze (MTM) paradigm. C57BL/6J mice were trained in the MTM which induced elevated levels o...

journal_title：Brain structure & function

authors： Ghafari M,Falsafi SK,Szodorai E,Kim EJ,Li L,Höger H,Berger J,Fuchs K,Sieghart W,Lubec G

更新日期：2017-01-01 00:00:00

abstract：:Interest in the study of brain connectivity is growing, particularly in understanding the dynamics of the structural/functional connectivity relation. Structural and functional connectivity are most often analysed independently of each other. Track-weighted functional connectivity (TW-FC) was recently proposed as a me...

journal_title：Brain structure & function

authors： Calamante F,Smith RE,Liang X,Zalesky A,Connelly A

更新日期：2017-11-01 00:00:00

abstract：:Glutamatergic afferents from the cerebral cortex are the main excitatory drive of striatal projection neurons. The metabotropic glutamate receptor 4 (mGluR4) presynaptically modulates transmission at corticostriatal synapses, and is considered as a potent drug target for Parkinson's disease and other brain disorders. ...

journal_title：Brain structure & function

authors： Iskhakova L,Smith Y

更新日期：2016-12-01 00:00:00

abstract：:The frontal pole corresponds to Brodmann area (BA) 10, the largest single architectonic area in the human frontal lobe. Generally, BA10 is thought to contain two or three subregions that subserve broad functions such as multitasking, social cognition, attention, and episodic memory. However, there is a substantial deb...

journal_title：Brain structure & function

authors： Moayedi M,Salomons TV,Dunlop KA,Downar J,Davis KD

更新日期：2015-09-01 00:00:00

abstract：:The medial septum and diagonal band of Broca (MSDB) influence hippocampal function through cholinergic, GABAergic, and glutamatergic septohippocampal neurons. Non-selective damage of the MSDB or intraseptal scopolamine impairs classical conditioning of the eyeblink response (CCER). Scopolamine preferentially inhibits ...

journal_title：Brain structure & function

authors： Roland JJ,Janke KL,Servatius RJ,Pang KC

更新日期：2014-07-01 00:00:00

abstract：:Nitric oxide (NO) is well demonstrated to act as a neuronal messenger in neurotransmission in vertebrate animals. We are for the first time reporting nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d) and neuronal nitric oxide synthase (nNOS) in the Mauthner cells (MC) of the carp, Labeo rohita brain dur...

journal_title：Brain structure & function

authors： Palande NV,Biswas S,Jadhao AG

更新日期：2011-03-01 00:00:00

abstract：:The interthalamic adhesion (ITA) is an understudied neuroanatomical structure that forms a bridge of tissue connecting the thalamus of each hemisphere across the midline whose functional significance remains largely unknown. The likelihood of ITA absence has been reported in some studies to be increased in males, but ...

journal_title：Brain structure & function

authors： Damle NR,Ikuta T,John M,Peters BD,DeRosse P,Malhotra AK,Szeszko PR

更新日期：2017-07-01 00:00:00

abstract：:Brain pathology in Friedreich ataxia is characterized by progressive degeneration of nervous tissue in the brainstem, cerebellum and cerebellar peduncles. Evidence of cerebral involvement is however equivocal. This brain imaging study investigates cerebello-cerebral white matter connectivity in Friedreich ataxia with ...

journal_title：Brain structure & function

authors： Zalesky A,Akhlaghi H,Corben LA,Bradshaw JL,Delatycki MB,Storey E,Georgiou-Karistianis N,Egan GF

更新日期：2014-05-01 00:00:00

abstract：:Regulator of G protein signaling 14 (RGS14) is a multifunctional signaling protein primarily expressed in mouse pyramidal neurons of hippocampal area CA2 where it regulates synaptic plasticity important for learning and memory. However, very little is known about RGS14 protein expression in the primate brain. Here, we...

journal_title：Brain structure & function

authors： Squires KE,Gerber KJ,Pare JF,Branch MR,Smith Y,Hepler JR

更新日期：2018-01-01 00:00:00

abstract：:The purpose of this study was to measure the average corpus callosum volume of normal Koreans (aged in their 20s or 40s) and to analyze the effects of gender, age, and body parameters, such as height and weight on corpus callosum size. Magnetic resonance brain images were recorded for 68 people in their 20s (29 men, 3...

journal_title：Brain structure & function

authors： Lee BY,Sohn JH,Choi MH,Lee SJ,Kim HS,Yang JW,Choi JS,Kim HS,Yi JH,Tack GR,Chung SC

更新日期：2009-09-01 00:00:00

abstract：:Early-life sleep deprivation (ESD) is a serious condition with severe metabolic sequelae. The pineal hormone melatonin plays an important role in homeostatic regulation of metabolic function. Considering norepinephrine-mediated Ca(2+) influx and subsequent protein kinase A (PKA) activation is responsible for downstrea...

journal_title：Brain structure & function

authors： Chen LY,Tiong C,Tsai CH,Liao WC,Yang SF,Youn SC,Mai FD,Chang HM

更新日期：2015-03-01 00:00:00

abstract：:The hippocampal formation is important for higher brain functions such as spatial navigation and the consolidation of memory, and it contributes to abilities thought to be uniquely human, yet little is known about how the human hippocampal formation compares to that of our closest living relatives, the chimpanzees. To...

journal_title：Brain structure & function

authors： Rogers Flattery CN,Rosen RF,Farberg AS,Dooyema JM,Hof PR,Sherwood CC,Walker LC,Preuss TM

更新日期：2020-11-01 00:00:00

abstract：:The process of learning mainly depends on the ability to store new information, while the ability to retrieve this information and express appropriate behaviors are also crucial for the adaptation of individuals to environmental cues. Thereby, all three components contribute to the cognitive fitness of an individual. ...

journal_title：Brain structure & function

authors： Zhang CL,Houbaert X,Lepleux M,Deshors M,Normand E,Gambino F,Herzog E,Humeau Y

更新日期：2015-11-01 00:00:00

abstract：:Two anorexigenic peptides, thyrotropin-releasing hormone (TRH) and urocortin 3 (UCN3), are co-expressed in a continuous neuronal group that extends from the perifornical area to the bed nucleus of stria terminalis, raising the possibility that this cell group may be involved in the regulation of energy homeostasis. In...

journal_title：Brain structure & function

authors： Péterfi Z,Farkas E,Nagyunyomi-Sényi K,Kádár A,Ottó S,Horváth A,Füzesi T,Lechan RM,Fekete C

更新日期：2018-04-01 00:00:00

abstract：:Retinoic acid, the active form of the nutrient vitamin A, regulates several facets of neuronal plasticity in the hippocampus, including neurogenesis and synaptic strength, acting via specific retinoic acid receptors (RARs). Essential for conversion of vitamin A to retinoic acid is the enzyme retinaldehyde dehydrogenas...

journal_title：Brain structure & function

authors： Fragoso YD,Shearer KD,Sementilli A,de Carvalho LV,McCaffery PJ

更新日期：2012-04-01 00:00:00

abstract：:Recently, neuroimaging-based Alzheimer's disease (AD) or mild cognitive impairment (MCI) diagnosis has attracted researchers in the field, due to the increasing prevalence of the diseases. Unfortunately, the unfavorable high-dimensional nature of neuroimaging data, but a limited small number of samples available, make...

journal_title：Brain structure & function

authors： Suk HI,Lee SW,Shen D,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2016-06-01 00:00:00

abstract：:Sensory neurons of the jugular vagal ganglia innervate the respiratory tract and project to the poorly studied medullary paratrigeminal nucleus. In the present study, we used neuroanatomical tracing, pharmacology and physiology in guinea pig to investigate the paratrigeminal neural circuits mediating jugular ganglia-e...

journal_title：Brain structure & function

authors： Driessen AK,Farrell MJ,Dutschmann M,Stanic D,McGovern AE,Mazzone SB

更新日期：2018-12-01 00:00:00

abstract：:The axon initial segment (AIS) is responsible for both the modulation of action potentials and the maintenance of neuronal polarity. Yet, the molecular mechanisms controlling its assembly are incompletely understood. Our study in single electroporated motor neurons in mouse embryos revealed that AnkyrinG (AnkG), the A...

journal_title：Brain structure & function

authors： Le Bras B,Fréal A,Czarnecki A,Legendre P,Bullier E,Komada M,Brophy PJ,Davenne M,Couraud F

更新日期：2014-07-01 00:00:00

abstract：:SK2 (KCa2.2) channels are voltage-independent Ca2+-activated K+ channels that regulate neuronal excitability in brain regions important for memory formation. In this study, we investigated the distribution and expression of SK2 channels in human brain by Western blot analysis and immunohistochemistry. Immunoblot analy...

journal_title：Brain structure & function

authors： Willis M,Trieb M,Leitner I,Wietzorrek G,Marksteiner J,Knaus HG

更新日期：2017-03-01 00:00:00

abstract：:A hierarchical and modular organization is a central hypothesis in the current primate model of auditory cortex (AC) but lacks validation in humans. Here we investigated whether fMRI connectivity at rest and during active tasks is informative of the functional organization of human AC. Identical pitch-varying sounds w...

journal_title：Brain structure & function

authors： Häkkinen S,Rinne T

更新日期：2018-06-01 00:00:00