Small-conductance calcium-activated potassium type 2 channels (SK2, KCa2.2) in human brain.

abstract：:The mammalian superior paraolivary nucleus (SPON) is a major source of GABAergic inhibition to neurons in the inferior colliculus (IC), a well-studied midbrain nucleus that is the site of convergence and integration for the majority ascending auditory pathways en route to the cortex. Neurons in the SPON and IC exhibit...

journal_title：Brain structure & function

authors： Felix RA 2nd,Magnusson AK,Berrebi AS

更新日期：2015-09-01 00:00:00

abstract：:The auditory midbrain (inferior colliculus, IC) plays an important role in sound processing, acting as hub for acoustic information extraction and for the implementation of fast audio-motor behaviors. IC neurons are topographically organized according to their sound frequency preference: dorsal IC regions encode low f...

journal_title：Brain structure & function

authors： González-Palomares E,López-Jury L,García-Rosales F,Hechavarria JC

更新日期：2021-01-01 00:00:00

abstract：:Emerging data support roles for microRNA (miRNA) in the pathogenesis of various neurologic disorders including epilepsy. MicroRNA-134 (miR-134) is enriched in dendrites of hippocampal neurons, where it negatively regulates spine volume. Recent work identified upregulation of miR-134 in experimental and human epilepsy....

journal_title：Brain structure & function

authors： Jimenez-Mateos EM,Engel T,Merino-Serrais P,Fernaud-Espinosa I,Rodriguez-Alvarez N,Reynolds J,Reschke CR,Conroy RM,McKiernan RC,deFelipe J,Henshall DC

更新日期：2015-07-01 00:00:00

abstract：:Chemically mediated synaptic transmission results from fusion of synaptic vesicles with the presynaptic plasma membrane, subsequent release of the vesicular content into the cleft and binding to postsynaptic receptors. Previous modelling studies of excitatory neurotransmitter glutamate were based on simplified geometr...

journal_title：Brain structure & function

authors： Boucher J,Kröger H,Sík A

更新日期：2010-07-01 00:00:00

abstract：:The midline and intralaminar thalamic nuclei (MITN), locus coeruleus (LC) and cingulate cortex contain nociceptive neurons. The MITN that project to cingulate cortex have a prominent innervation by norepinephrinergic axons primarily originating from the LC. The hypothesis explored in this study is that MITN neurons th...

journal_title：Brain structure & function

authors： Vogt BA,Hof PR,Friedman DP,Sikes RW,Vogt LJ

更新日期：2008-08-01 00:00:00

abstract：:Brain pathology in Friedreich ataxia is characterized by progressive degeneration of nervous tissue in the brainstem, cerebellum and cerebellar peduncles. Evidence of cerebral involvement is however equivocal. This brain imaging study investigates cerebello-cerebral white matter connectivity in Friedreich ataxia with ...

journal_title：Brain structure & function

authors： Zalesky A,Akhlaghi H,Corben LA,Bradshaw JL,Delatycki MB,Storey E,Georgiou-Karistianis N,Egan GF

更新日期：2014-05-01 00:00:00

abstract：:The anatomic gene expression atlas (AGEA) of the adult mouse brain of the Allen Institute for Brain Science is a transcriptome-based atlas of the adult C57Bl/6 J mouse brain, based on the extensive in situ hybridization dataset of the Institute. This spatial mapping of the gene expression levels of mice under baseline...

journal_title：Brain structure & function

authors： Kalafatakis I,Kalafatakis K,Tsimpolis A,Giannakeas N,Tsipouras M,Tzallas A,Karagogeos D

更新日期：2020-09-01 00:00:00

abstract：:The basal ganglia of the laboratory rat consist of a few core regions that are specifically interconnected by efferents and afferents of the central nervous system. In nearly 800 reports of tract-tracing investigations the connectivity of the basal ganglia is documented. The readout of connectivity data and the collat...

journal_title：Brain structure & function

authors： Schmitt O,Eipert P,Kettlitz R,Leßmann F,Wree A

更新日期：2016-03-01 00:00:00

abstract：:Anterior cingulate cortex (ACC) input to the claustrum is required for top-down cognitive control of action. By virtue of its widespread cortical connectivity, the claustrum is anatomically situated to process and broadcast top-down signals from ACC to downstream cortices. To gain a deeper understanding of claustrum p...

journal_title：Brain structure & function

authors： White MG,Mathur BN

更新日期：2018-12-01 00:00:00

abstract：:Despite being historically one of the first brain regions linked to memory loss, there remains controversy over the core features of diencephalic amnesia as well as the critical site for amnesia to occur. The mammillary bodies and thalamus appear to be the primary locus of pathology in the cases of diencephalic amnesi...

journal_title：Brain structure & function

authors： Nelson AJD,Vann SD

更新日期：2017-07-01 00:00:00

abstract：:The 30-amino acid peptide Y-P30, generated from the N-terminus of the human dermcidin precursor protein, has been found to promote neuronal survival, cell migration and neurite outgrowth by enhancing the interaction of pleiotrophin and syndecan-3. We now show that Y-P30 activates Src kinase and extracellular signal-re...

journal_title：Brain structure & function

authors： Neumann JR,Dash-Wagh S,Jüngling K,Tsai T,Meschkat M,Räk A,Schönfelder S,Riedel C,Hamad MI,Wiese S,Pape HC,Gottmann K,Kreutz MR,Wahle P

更新日期：2015-07-01 00:00:00

abstract：:The tegmental pedunculopontine nucleus (PPN) is a basal ganglia-related structure that has recently gained renewed interest as a potential surgical target for the treatment of several aspects of Parkinson's disease. However, the underlying anatomical substrates sustaining the choice of the PPN nucleus as a surgical ca...

journal_title：Brain structure & function

authors： Barroso-Chinea P,Rico AJ,Conte-Perales L,Gómez-Bautista V,Luquin N,Sierra S,Roda E,Lanciego JL

更新日期：2011-11-01 00:00:00

abstract：:What changes in cortical organisation characterise global and localised variation between humans and chimpanzees remains a topic of considerable interest in evolutionary neuroscience. Here, we examined regional variation in cortical thickness, gyrification and white matter in samples of human and chimpanzee brains. Bo...

journal_title：Brain structure & function

authors： Hopkins WD,Li X,Crow T,Roberts N

更新日期：2017-01-01 00:00:00

abstract：:Neuronatomical and pharmacological studies have established GABA-mediated inhibition of the HPA axis at the level of the PVN. The origin of this innervation is a series of local hypothalamic and adjacent forebrain regions that project to stress-integrative hypophysiotropic CRH neurons. While a role in tonic inhibition...

journal_title：Brain structure & function

authors： Cullinan WE,Ziegler DR,Herman JP

更新日期：2008-09-01 00:00:00

abstract：:Different genotypic combinations of COMT and DRD2 can generate multiple subgroups with different levels of dopamine signaling. Its modulations on brain properties can be investigated by analyzing the combined gene effects of COMT and DRD2. However, the inherent association between modulation patterns of the dopamine s...

journal_title：Brain structure & function

authors： Xu J,Qin W,Liu B,Jiang T,Yu C

更新日期：2016-11-01 00:00:00

abstract：:The amygdala and medial prefrontal cortex (mPFC) are highly interconnected telencephalic areas critical for cognitive processes, including associative learning and decision making. Both structures strongly innervate the lateral hypothalamus (LHA), an important component of the networks underlying the control of feedin...

journal_title：Brain structure & function

authors： Reppucci CJ,Petrovich GD

更新日期：2016-07-01 00:00:00

abstract：:Serotonergic neurons of the raphe nuclei exhibit anatomical, neurochemical and elecrophysiological heterogeneity that likely underpins their specific role in multiple behaviors. However, the precise organization of serotonin (5-HT) neurons to orchestrate 5-HT release patterns throughout the brain is not well understoo...

journal_title：Brain structure & function

authors： Fernandez SP,Cauli B,Cabezas C,Muzerelle A,Poncer JC,Gaspar P

更新日期：2016-11-01 00:00:00

abstract：:Serotonergic cells are among the earliest neurons to be born in the developing central nervous system and serotonin is known to regulate the development of the nervous system. One of the major targets of the activity of serotonergic cells is the serotonin 1A receptor (5-HT1A), an ancestral archetypical serotonin recep...

journal_title：Brain structure & function

authors： Cornide-Petronio ME,Anadón R,Barreiro-Iglesias A,Rodicio MC

更新日期：2013-09-01 00:00:00

abstract：:Sublineage diversification of specific neural cell classes occurs in complex as well as simply organized regions of the central and peripheral nervous systems; the significance of the phenomenon, however, remains insufficiently understood. The unipolar brush cells (UBCs) are glutamatergic cerebellar interneurons that ...

journal_title：Brain structure & function

authors： Sekerková G,Watanabe M,Martina M,Mugnaini E

更新日期：2014-03-01 00:00:00

abstract：:Nitric oxide (NO) is well demonstrated to act as a neuronal messenger in neurotransmission in vertebrate animals. We are for the first time reporting nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d) and neuronal nitric oxide synthase (nNOS) in the Mauthner cells (MC) of the carp, Labeo rohita brain dur...

journal_title：Brain structure & function

authors： Palande NV,Biswas S,Jadhao AG

更新日期：2011-03-01 00:00:00

abstract：:Forebrain serotonin relevant for many psychological disorders arises in the hindbrain, primarily within the dorsal and median raphe nuclei (DR and MR). These nuclei are heterogeneous, containing several distinct groups of serotonin neurons. Here, new insight into the afferent and efferent connectivity of these areas i...

journal_title：Brain structure & function

authors： Commons KG

更新日期：2016-09-01 00:00:00

abstract：:The vascular organization of the human brain can determine neurological and neurophysiological functions, yet thus far it has not been comprehensively mapped. Aging and diseases such as dementia are known to be associated with changes to the vasculature and normative data could help detect these vascular changes in ne...

journal_title：Brain structure & function

authors： Huck J,Wanner Y,Fan AP,Jäger AT,Grahl S,Schneider U,Villringer A,Steele CJ,Tardif CL,Bazin PL,Gauthier CJ

更新日期：2019-09-01 00:00:00

abstract：:Perineuronal nets (PNNs) are aggregates of extracellular matrix molecules surrounding several types of neurons in the adult CNS, which contribute to stabilising neuronal connections. Interestingly, a reduction of PNN number and staining intensity has been observed in conditions associated with plasticity in the adult ...

journal_title：Brain structure & function

authors： Faralli A,Dagna F,Albera A,Bekku Y,Oohashi T,Albera R,Rossi F,Carulli D

更新日期：2016-07-01 00:00:00

abstract：:The octopus arm contains a tridimensional array of muscles with a massive sensory-motor system. We herein provide the first evidence for the existence of serotonin (5-HT) in the octopus arm nervous system and investigated its distribution using immunohistochemistry. 5-HT-like immunoreactive (5-HT-lir) nerve cell bodie...

journal_title：Brain structure & function

authors： Bellier JP,Xie Y,Farouk SM,Sakaue Y,Tooyama I,Kimura H

更新日期：2017-09-01 00:00:00

abstract：:Diffusion tensor imaging (DTI) has become a valuable tool to investigate white matter integrity in the brain. DTI also gives contrast in gray matter, which has been relatively little explored in studies assessing post-injury structural abnormalities. The present study was designed to compare white and gray matter reor...

journal_title：Brain structure & function

authors： Sierra A,Laitinen T,Gröhn O,Pitkänen A

更新日期：2015-03-01 00:00:00

abstract：:Previous work in the precocious rodent Octodon degus has shown that exposure to early life stress (ELS) (induced by repeated parental separation) results in changes of excitatory, inhibitory and modulatory transmitter systems in prefrontal and limbic regions of the male brain. The aim of this study was to test the hyp...

journal_title：Brain structure & function

authors： Kunzler J,Braun K,Bock J

更新日期：2015-03-01 00:00:00

abstract：:To provide information on the glutamatergic synapses on the trigeminal motoneurons, which may be important for understanding the mechanism of control of jaw movements, we investigated the distribution of vesicular glutamate transporter (VGLUT)1-immunopositive (+) and VGLUT2 + axon terminals (boutons) on the rat jaw-cl...

journal_title：Brain structure & function

authors： Park SK,Ko SJ,Paik SK,Rah JC,Lee KJ,Bae YC

更新日期：2018-06-01 00:00:00

abstract：:Finding the neuroanatomical correlates of prematurity is vital to understanding which structures are affected, and to designing efficient prevention and treatment strategies. Converging results reveal that thalamic abnormalities are important indicators of prematurity. However, little is known about the localization o...

journal_title：Brain structure & function

authors： Lao Y,Wang Y,Shi J,Ceschin R,Nelson MD,Panigrahy A,Leporé N

更新日期：2016-01-01 00:00:00

abstract：:The hippocampal formation is important for higher brain functions such as spatial navigation and the consolidation of memory, and it contributes to abilities thought to be uniquely human, yet little is known about how the human hippocampal formation compares to that of our closest living relatives, the chimpanzees. To...

journal_title：Brain structure & function

authors： Rogers Flattery CN,Rosen RF,Farberg AS,Dooyema JM,Hof PR,Sherwood CC,Walker LC,Preuss TM

更新日期：2020-11-01 00:00:00

abstract：:Dominant theories of episodic memory propose that a key mechanism of memory consolidation is replay-a process, whereby neural patterns of activation during learning are reinstated during offline post-learning periods. Here, we tested whether key signatures of replay defined by studies in rodents, such as recapitulatio...

journal_title：Brain structure & function

authors： Alm KH,Ngo CT,Olson IR

更新日期：2019-03-01 00:00:00