Multiscale single-cell analysis reveals unique phenotypes of raphe 5-HT neurons projecting to the forebrain.

abstract：:Olfaction is one of the major sensory modalities that regulates food consumption and is in turn regulated by the feeding state. Given that the olfactory bulb has been shown to be a metabolic sensor, we explored whether the anterior piriform cortex (aPCtx)-a higher olfactory cortical processing area-had the same capaci...

journal_title：Brain structure & function

authors： Al Koborssy D,Palouzier-Paulignan B,Canova V,Thevenet M,Fadool DA,Julliard AK

更新日期：2019-01-01 00:00:00

abstract：:There is limited information on the role of GABA type A receptors (GABAARs) containing α1, α5 and γ2 subunits in learning and memory. Here, we assessed the possible role of such receptors in spatial learning using the multiple T-maze (MTM) paradigm. C57BL/6J mice were trained in the MTM which induced elevated levels o...

journal_title：Brain structure & function

authors： Ghafari M,Falsafi SK,Szodorai E,Kim EJ,Li L,Höger H,Berger J,Fuchs K,Sieghart W,Lubec G

更新日期：2017-01-01 00:00:00

abstract：:Previous diffusion tensor imaging (DTI) studies have shown that various factors can affect white matter (WM) tract diffusivity. The aim of the present study was to investigate the effects of childhood adversity (CA), age and gender on WM diffusivity in tracts that are thought to be involved in emotional regulation in ...

journal_title：Brain structure & function

authors： Ugwu ID,Amico F,Carballedo A,Fagan AJ,Frodl T

更新日期：2015-07-01 00:00:00

abstract：:The frontotemporal cortical network is associated with behaviours such as impulsivity and aggression. The health of the uncinate fasciculus (UF) that connects the orbitofrontal cortex (OFC) with the anterior temporal lobe (ATL) may be a crucial determinant of behavioural regulation. Behavioural changes can emerge afte...

journal_title：Brain structure & function

authors： Goswami R,Dufort P,Tartaglia MC,Green RE,Crawley A,Tator CH,Wennberg R,Mikulis DJ,Keightley M,Davis KD

更新日期：2016-05-01 00:00:00

abstract：:The structure of neurons in the central auditory system is vulnerable to various kinds of acoustic exposures during the critical postnatal developmental period. Here we explored long-term effects of exposure to an acoustically enriched environment (AEE) during the third and fourth weeks of the postnatal period in rat ...

journal_title：Brain structure & function

authors： Svobodová Burianová J,Syka J

更新日期：2020-09-01 00:00:00

abstract：:Von Economo's neurons (VENs) are large, bipolar or corkscrew-shaped neurons located in layers III and V of the frontoinsular and the anterior cingulate cortices. VENs are reported to be altered in pathologies such as frontotemporal dementia and autism, in which the individual's self control is seriously compromised. T...

journal_title：Brain structure & function

authors： Cauda F,Torta DM,Sacco K,D'Agata F,Geda E,Duca S,Geminiani G,Vercelli A

更新日期：2013-01-01 00:00:00

abstract：:A rapidly increasing number of studies are quantifying the system-level network architecture of the human brain based on structural-to-structural and functional-to-functional relationships. However, a largely unexplored area is the nature and existence of "cross-modal" structural-functional relationships, in which, fo...

journal_title：Brain structure & function

authors： Harms MP,Wang L,Csernansky JG,Barch DM

更新日期：2013-01-01 00:00:00

abstract：:Neuroimaging studies have demonstrated that mental imagery and perception share similar neural substrates, however, there are still ambiguities according to different auditory imagery content. In addition, there is still a lack of information regarding the underlying neural correlation between the two modalities. In t...

journal_title：Brain structure & function

authors： Gu J,Zhang H,Liu B,Li X,Wang P,Wang B

更新日期：2019-11-01 00:00:00

abstract：:The insula is a brain structure implicated in disparate cognitive, affective, and regulatory functions, including interoceptive awareness, emotional responses, and empathic processes. While classically considered a limbic region, recent evidence from network analysis suggests a critical role for the insula, particular...

journal_title：Brain structure & function

authors： Menon V,Uddin LQ

更新日期：2010-06-01 00:00:00

abstract：:Stress impacts differently in distinct brain regions. However, so far few studies have focused on the differential responses triggered by stressful stimuli on the intrinsic functional heterogeneity of the hippocampal axis. In this study, we assessed the functional and structural alterations caused by exposure to a chr...

journal_title：Brain structure & function

authors： Pinto V,Costa JC,Morgado P,Mota C,Miranda A,Bravo FV,Oliveira TG,Cerqueira JJ,Sousa N

更新日期：2015-03-01 00:00:00

abstract：:It is well established that environmental influences play a key role in sculpting neuronal connectivity in the brain. One example is the olfactory sensory map of topographic axonal connectivity. While intrinsic odorant receptor signaling in olfactory sensory neurons (OSN) determines anterior-posterior counter gradient...

journal_title：Brain structure & function

authors： Login H,Butowt R,Bohm S

更新日期：2015-07-01 00:00:00

abstract：:Recent research has shown that at least two tryptophan hydroxylase (Tph) genes are present in gnathostome vertebrates, but it is not known when the duplication of the ancestral Tph gene took place during evolution. By their position as an out-group of gnathostomes, lampreys (agnathans) are key models to understand mo...

journal_title：Brain structure & function

authors： Cornide-Petronio ME,Anadón R,Rodicio MC,Barreiro-Iglesias A

更新日期：2013-03-01 00:00:00

abstract：:Rapid behavioral responses to unexpected events in the acoustic environment are critical for survival. Stimulus-specific adaptation (SSA) is the process whereby some auditory neurons respond better to rare stimuli than to repetitive stimuli. Most experiments on SSA have been performed under anesthesia, and it is unkno...

journal_title：Brain structure & function

authors： Duque D,Malmierca MS

更新日期：2015-11-01 00:00:00

abstract：:Functional connectivity (FC) reflects the coherence of spontaneous, low-frequency fluctuations in functional magnetic resonance imaging (fMRI) data. We report a behavior-based connectivity analysis method, in which whole-brain data are used to identify behaviorally relevant, intrinsic FC networks. Nineteen younger adu...

journal_title：Brain structure & function

authors： Chen NK,Chou YH,Song AW,Madden DJ

更新日期：2009-10-01 00:00:00

abstract：:Electrical stimulation of the dorsolateral periaqueductal gray (dlPAG) in rats has been shown to elicit panic-like behaviour and can be a useful as an unconditioned stimulus for modelling anticipatory fear and agoraphobia in a contextual fear conditioning paradigm. In this study, we further analysed our previous data ...

journal_title：Brain structure & function

authors： Tan SZK,Temel Y,Chan AY,Mok ATC,Perucho JAU,Blokland A,Aquili L,Lim WL,Lim LW

更新日期：2020-09-01 00:00:00

abstract：:The axon initial segment (AIS) is responsible for both the modulation of action potentials and the maintenance of neuronal polarity. Yet, the molecular mechanisms controlling its assembly are incompletely understood. Our study in single electroporated motor neurons in mouse embryos revealed that AnkyrinG (AnkG), the A...

journal_title：Brain structure & function

authors： Le Bras B,Fréal A,Czarnecki A,Legendre P,Bullier E,Komada M,Brophy PJ,Davenne M,Couraud F

更新日期：2014-07-01 00:00:00

abstract：:Prolactin is fundamental for the expression of maternal behaviour. In virgin female rats, prolactin administered upon steroid hormone priming accelerates the onset of maternal care. By contrast, the role of prolactin in mice maternal behaviour remains unclear. This study aims at characterizing central prolactin activi...

journal_title：Brain structure & function

authors： Salais-López H,Lanuza E,Agustín-Pavón C,Martínez-García F

更新日期：2017-03-01 00:00:00

abstract：:Recently, neuroimaging-based Alzheimer's disease (AD) or mild cognitive impairment (MCI) diagnosis has attracted researchers in the field, due to the increasing prevalence of the diseases. Unfortunately, the unfavorable high-dimensional nature of neuroimaging data, but a limited small number of samples available, make...

journal_title：Brain structure & function

authors： Suk HI,Lee SW,Shen D,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2016-06-01 00:00:00

abstract：:Goal-directed behavior has been shown to be affected by consciously and subliminally induced conflicts. Both types of conflict conjointly modulate behavioral performance, but the underlying neuronal mechanisms have remained unclear. While cognitive control is linked to oscillations in the theta frequency band, there a...

journal_title：Brain structure & function

authors： Bensmann W,Zink N,Mückschel M,Beste C,Stock AK

更新日期：2019-06-01 00:00:00

abstract：:MRI was employed to follow the neurodegenerative foci and the localization of inflammatory cells by magnetically labeled CD4+ or CD8+ lymphocytes in the ischemia/reperfusion long-lived rats (9 and 13 months after 10 min of cardiac arrest). MRI of ischemic rats showed: (1) blood-brain barrier (BBB) leakage in the area ...

journal_title：Brain structure & function

authors： Sekeljic V,Bataveljic D,Stamenkovic S,Ułamek M,Jabłoński M,Radenovic L,Pluta R,Andjus PR

更新日期：2012-04-01 00:00:00

abstract：:Interest in the study of brain connectivity is growing, particularly in understanding the dynamics of the structural/functional connectivity relation. Structural and functional connectivity are most often analysed independently of each other. Track-weighted functional connectivity (TW-FC) was recently proposed as a me...

journal_title：Brain structure & function

authors： Calamante F,Smith RE,Liang X,Zalesky A,Connelly A

更新日期：2017-11-01 00:00:00

abstract：:The basal ganglia are a group of subpallial nuclei that play an important role in motor, emotional, and cognitive functions. Morphological changes and disrupted afferent/efferent connections in the basal ganglia have been associated with a variety of neurological disorders including psychiatric and movement disorders....

journal_title：Brain structure & function

authors： Ullmann JF,Watson C,Janke AL,Kurniawan ND,Paxinos G,Reutens DC

更新日期：2014-07-01 00:00:00

abstract：:The fornix is the primary efferent pathway of the hippocampus and plays a central role in memory circuitry. Diffusion tensor imaging has shown changes in the fornix with typical development and aging. Here, the fornix was investigated in 903 healthy young adult participants aged 22-36 years old from the high-spatial r...

journal_title：Brain structure & function

authors： Cahn AJ,Little G,Beaulieu C,Tétreault P

更新日期：2021-01-02 00:00:00

abstract：:Dopaminergic (DA) inputs to the basolateral nuclear complex of the amygdala (BLC) are critical for several important functions, including reward-related learning, drug-stimulus learning, and fear conditioning. Despite the importance of the DA projection to the BLC, very little is known about which neuronal subpopulati...

journal_title：Brain structure & function

authors： Muller JF,Mascagni F,McDonald AJ

更新日期：2009-02-01 00:00:00

abstract：:The anatomic gene expression atlas (AGEA) of the adult mouse brain of the Allen Institute for Brain Science is a transcriptome-based atlas of the adult C57Bl/6 J mouse brain, based on the extensive in situ hybridization dataset of the Institute. This spatial mapping of the gene expression levels of mice under baseline...

journal_title：Brain structure & function

authors： Kalafatakis I,Kalafatakis K,Tsimpolis A,Giannakeas N,Tsipouras M,Tzallas A,Karagogeos D

更新日期：2020-09-01 00:00:00

abstract：:Chemically mediated synaptic transmission results from fusion of synaptic vesicles with the presynaptic plasma membrane, subsequent release of the vesicular content into the cleft and binding to postsynaptic receptors. Previous modelling studies of excitatory neurotransmitter glutamate were based on simplified geometr...

journal_title：Brain structure & function

authors： Boucher J,Kröger H,Sík A

更新日期：2010-07-01 00:00:00

abstract：:The cerebellum receives sensory signals from spinocerebellar (lower limbs) and dorsal column nuclei (upper limbs) mossy fibers. In the cerebellum, mossy fibers terminate in bands that are topographically aligned with stripes of Purkinje cells. While much is known about the molecular heterogeneity of Purkinje cell stri...

journal_title：Brain structure & function

authors： Gebre SA,Reeber SL,Sillitoe RV

更新日期：2012-04-01 00:00:00

abstract：:The tegmental pedunculopontine nucleus (PPN) is a basal ganglia-related structure that has recently gained renewed interest as a potential surgical target for the treatment of several aspects of Parkinson's disease. However, the underlying anatomical substrates sustaining the choice of the PPN nucleus as a surgical ca...

journal_title：Brain structure & function

authors： Barroso-Chinea P,Rico AJ,Conte-Perales L,Gómez-Bautista V,Luquin N,Sierra S,Roda E,Lanciego JL

更新日期：2011-11-01 00:00:00

abstract：:Recent views of information processing in the (human) brain emphasize the hierarchical structure of the central nervous system, which is assumed to form the basis of a functional hierarchy. Hierarchical predictive processing refers to the notion that higher levels try to predict activity in lower areas, while lower le...

journal_title：Brain structure & function

authors： Kellermann T,Scholle R,Schneider F,Habel U

更新日期：2017-03-01 00:00:00

abstract：:Reduction in the amount of brain-derived neurotrophic factor (BDNF) in corticostriatal afferents is thought to contribute to the vulnerability of medium spiny striatal neurons in Huntington's disease. In young Bdnf heterozygous ((+/-)) mice, striatal medium spiny neurons (MSNs) express less preprodynorphin (PPD), prep...

journal_title：Brain structure & function

authors： Saylor AJ,McGinty JF

更新日期：2010-08-01 00:00:00