Postnatal exposure to an acoustically enriched environment alters the morphology of neurons in the adult rat auditory system.

abstract：:Electrical stimulation of the dorsolateral periaqueductal gray (dlPAG) in rats has been shown to elicit panic-like behaviour and can be a useful as an unconditioned stimulus for modelling anticipatory fear and agoraphobia in a contextual fear conditioning paradigm. In this study, we further analysed our previous data ...

journal_title：Brain structure & function

authors： Tan SZK,Temel Y,Chan AY,Mok ATC,Perucho JAU,Blokland A,Aquili L,Lim WL,Lim LW

更新日期：2020-09-01 00:00:00

abstract：:One of the major challenges of functional magnetic resonance imaging (fMRI) data analysis is to develop simple and reliable methods to correlate brain regions with functionality. In this paper, we employ a detrending-based fractal method, called detrended fluctuation analysis (DFA), to identify brain activity from fMR...

journal_title：Brain structure & function

authors： Hu J,Lee JM,Gao J,White KD,Crosson B

更新日期：2008-02-01 00:00:00

abstract：:The hippocampal formation is important for higher brain functions such as spatial navigation and the consolidation of memory, and it contributes to abilities thought to be uniquely human, yet little is known about how the human hippocampal formation compares to that of our closest living relatives, the chimpanzees. To...

journal_title：Brain structure & function

authors： Rogers Flattery CN,Rosen RF,Farberg AS,Dooyema JM,Hof PR,Sherwood CC,Walker LC,Preuss TM

更新日期：2020-11-01 00:00:00

abstract：:Emerging data support roles for microRNA (miRNA) in the pathogenesis of various neurologic disorders including epilepsy. MicroRNA-134 (miR-134) is enriched in dendrites of hippocampal neurons, where it negatively regulates spine volume. Recent work identified upregulation of miR-134 in experimental and human epilepsy....

journal_title：Brain structure & function

authors： Jimenez-Mateos EM,Engel T,Merino-Serrais P,Fernaud-Espinosa I,Rodriguez-Alvarez N,Reynolds J,Reschke CR,Conroy RM,McKiernan RC,deFelipe J,Henshall DC

更新日期：2015-07-01 00:00:00

abstract：:Pigeons are classic animal models for learning, memory, and cognition. The majority of the current understanding about avian neurobiology outside of the domain of the song system has been established using pigeons. Since MRI represents an increasingly relevant tool for comparative neuroscience, a 3-dimensional MRI-bas...

journal_title：Brain structure & function

authors： Güntürkün O,Verhoye M,De Groof G,Van der Linden A

更新日期：2013-01-01 00:00:00

abstract：:Ambulatory locomotion in the rodent is robustly activated by unilateral infusions into the basal forebrain of type A gamma-aminobutyric acid receptor antagonists, such as bicuculline and picrotoxin. The present study was carried out to better localize the neuroanatomical substrate(s) underlying this effect. To accompl...

journal_title：Brain structure & function

authors： Zahm DS,Schwartz ZM,Lavezzi HN,Yetnikoff L,Parsley KP

更新日期：2014-03-01 00:00:00

abstract：:Neocortical layer VI is critically involved in thalamocortical activity changes during the sleep/wake cycle. It receives dense projections from thalamic nuclei sensitive to the wake-promoting neuropeptides orexins, and its deepest part, layer VIb, is the only cortical lamina reactive to orexins. This convergence of wa...

journal_title：Brain structure & function

authors： Hay YA,Andjelic S,Badr S,Lambolez B

更新日期：2015-11-01 00:00:00

abstract：:An account of work performed at the UNA laboratories since 1992 on the detection and description of interlaminar glial processes, is presented. The incidental observation (serendipity) of longer than expected glial processes in the superficial layers of the cerebral cortex in hemiparkinsonian Cebus apella monkeys, was...

journal_title：Brain structure & function

authors： Colombo JA

更新日期：2017-04-01 00:00:00

abstract：:The organization of the pallial derivatives across vertebrates follows a comparable elementary arrangement, although not all of them possess a layered cortical structure as sophisticated as the cerebral cortex of mammals. However, its expansion along evolution has only been possible by the development and coevolution ...

journal_title：Brain structure & function

authors： Jiménez S,López JM,Lozano D,Morona R,González A,Moreno N

更新日期：2020-09-01 00:00:00

abstract：:Finding the neuroanatomical correlates of prematurity is vital to understanding which structures are affected, and to designing efficient prevention and treatment strategies. Converging results reveal that thalamic abnormalities are important indicators of prematurity. However, little is known about the localization o...

journal_title：Brain structure & function

authors： Lao Y,Wang Y,Shi J,Ceschin R,Nelson MD,Panigrahy A,Leporé N

更新日期：2016-01-01 00:00:00

abstract：:Melatonin, through its different receptors, has pleiotropic functions in mammalian brain. Melatonin is secreted mainly by the pineal gland and exerts its effects via receptor-mediated and non-receptor-mediated actions. With recent advancement in neuroanatomical mapping, we may now understand better the localizations o...

journal_title：Brain structure & function

authors： Ng KY,Leong MK,Liang H,Paxinos G

更新日期：2017-09-01 00:00:00

abstract：:Dopamine, acting at the D1 family receptors (D1R) is critical for the functioning of the amygdala, including fear conditioning and cue-induced reinstatement of drug self administration. However, little is known about the different contributions of the two D1R subtypes, D(1) and D(5). We identified D(1)-immunoreactive ...

journal_title：Brain structure & function

authors： Muly EC,Senyuz M,Khan ZU,Guo JD,Hazra R,Rainnie DG

更新日期：2009-09-01 00:00:00

abstract：:Brain pathology in Friedreich ataxia is characterized by progressive degeneration of nervous tissue in the brainstem, cerebellum and cerebellar peduncles. Evidence of cerebral involvement is however equivocal. This brain imaging study investigates cerebello-cerebral white matter connectivity in Friedreich ataxia with ...

journal_title：Brain structure & function

authors： Zalesky A,Akhlaghi H,Corben LA,Bradshaw JL,Delatycki MB,Storey E,Georgiou-Karistianis N,Egan GF

更新日期：2014-05-01 00:00:00

abstract：:Glycoproteins are complex molecules of the cell surface and the extracellular matrix (ECM) playing a fundamental role in the migration, guidance and synapse formation of neurons. In the present study, the glycosylated protein composition and localization were investigated in the adult and developing CNS of an aquatic ...

journal_title：Brain structure & function

authors： Serfozo Z,Elekes K

更新日期：2009-12-01 00:00:00

abstract：:We are often faced with situations requiring the execution of a coordinated cascade of different actions to achieve a goal, but we can apply different strategies to do so. Until now, these different action cascading strategies have, however, not been examined with respect to possible effects of aging. We tackled this ...

journal_title：Brain structure & function

authors： Stock AK,Gohil K,Beste C

更新日期：2016-06-01 00:00:00

abstract：:In recent years, the demonstration that structural changes can occur in the human brain beyond those associated with development, ageing and neuropathology has revealed a new approach to studying the neural basis of behaviour. In this review paper, we focus on structural imaging studies of language that have utilised ...

journal_title：Brain structure & function

authors： Richardson FM,Price CJ

更新日期：2009-10-01 00:00:00

abstract：:Animal models of Alzheimer's disease (AD) can be used to determine the progressive neurodegeneration characteristics of AD in vivo using magnetic resonance imaging (MRI). Given the need for therapeutic interventions before the onset of frank AD, it is critical to examine if AD models demonstrate neuroanatomical remode...

journal_title：Brain structure & function

authors： Kong V,Devenyi GA,Gallino D,Ayranci G,Germann J,Rollins C,Chakravarty MM

更新日期：2018-09-01 00:00:00

abstract：:The effect of intracortical microstimulation has been studied in several cortical areas from motor to sensory areas. The frontal pole has received particular attention, and several microstimulation studies have been conducted in the frontal eye field, supplementary eye field, and the premotor ear-eye field, but no mic...

journal_title：Brain structure & function

authors： Lanzilotto M,Perciavalle V,Lucchetti C

更新日期：2015-03-01 00:00:00

abstract：:Glucose metabolism produces, by oxidative phosphorylation, more than 15 times the amount of energy generated by aerobic glycolysis. Nonetheless, aerobic glycolysis remains a prevalent metabolic pathway in the brain. Here we review evidence suggesting that this pathway contributes essential molecules to the biomass of ...

journal_title：Brain structure & function

authors： Bauernfeind AL,Barks SK,Duka T,Grossman LI,Hof PR,Sherwood CC

更新日期：2014-07-01 00:00:00

abstract：:Two anorexigenic peptides, thyrotropin-releasing hormone (TRH) and urocortin 3 (UCN3), are co-expressed in a continuous neuronal group that extends from the perifornical area to the bed nucleus of stria terminalis, raising the possibility that this cell group may be involved in the regulation of energy homeostasis. In...

journal_title：Brain structure & function

authors： Péterfi Z,Farkas E,Nagyunyomi-Sényi K,Kádár A,Ottó S,Horváth A,Füzesi T,Lechan RM,Fekete C

更新日期：2018-04-01 00:00:00

abstract：:Projections from the prefrontal cortex (PFC) to the amygdala (AMG) regulate affective behaviors in a manner that is modulated by dopamine (DA). Although PFC and DA inputs overlap within the basolateral nucleus (BLA) and intercalated cell masses (ICMs), the spatial relationship between these afferents has not been inve...

journal_title：Brain structure & function

authors： Pinto A,Sesack SR

更新日期：2008-09-01 00:00:00

abstract：:The insula is a brain structure implicated in disparate cognitive, affective, and regulatory functions, including interoceptive awareness, emotional responses, and empathic processes. While classically considered a limbic region, recent evidence from network analysis suggests a critical role for the insula, particular...

journal_title：Brain structure & function

authors： Menon V,Uddin LQ

更新日期：2010-06-01 00:00:00

abstract：:Some of the known sex differences in white matter emerge during adolescence. Here, we replicate and extend our previous findings of sex differences in the structure of the corticospinal tract (Perrin et al. 2009; Hervé et al. 2009). In a large normative sample of adolescents, we observed age × sex interactions in the ...

journal_title：Brain structure & function

authors： Pangelinan MM,Leonard G,Perron M,Pike GB,Richer L,Veillette S,Pausova Z,Paus T

更新日期：2016-03-01 00:00:00

abstract：:Recently, there have been great interests for computer-aided diagnosis of Alzheimer's disease (AD) and its prodromal stage, mild cognitive impairment (MCI). Unlike the previous methods that considered simple low-level features such as gray matter tissue volumes from MRI, and mean signal intensities from PET, in this p...

journal_title：Brain structure & function

authors： Suk HI,Lee SW,Shen D,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2015-03-01 00:00:00

abstract：:Adult hippocampal neural stem cells (NSC) are an intriguing source for cell replacement or could serve as delivery vehicles for therapeutic genes. We recently reported selective transduction of adult mouse NSC in the DG by in vivo injection of GFP encoding adenoviral (Ad) vectors engineered to bind NSC-specific peptid...

journal_title：Brain structure & function

authors： Hildebrandt S,Schmidt A,Stoll A,Schmitt O,Köhling R,Wree A,Haas SJ,Pützer BM

更新日期：2010-08-01 00:00:00

abstract：:Reduction in the amount of brain-derived neurotrophic factor (BDNF) in corticostriatal afferents is thought to contribute to the vulnerability of medium spiny striatal neurons in Huntington's disease. In young Bdnf heterozygous ((+/-)) mice, striatal medium spiny neurons (MSNs) express less preprodynorphin (PPD), prep...

journal_title：Brain structure & function

authors： Saylor AJ,McGinty JF

更新日期：2010-08-01 00:00:00

abstract：:Despite robust sex differences in behavioral responses to drugs of abuse, relatively little is known about structural sex differences in synaptic connectivity of reward circuits such as in the nucleus accumbens (NAc). Previously, we showed that distal dendritic spine density on medium spiny neurons in the NAc is highe...

journal_title：Brain structure & function

authors： Wissman AM,May RM,Woolley CS

更新日期：2012-04-01 00:00:00

abstract：:Dopaminergic neuromodulation is critically important for brain and cognitive integrity. The DRD2/ANKK1 Taq1A polymorphism is associated with striatal dopamine (DA) D2 receptor availability. Some previous studies have found that the A allele of the Taq1A polymorphism influences brain structure, but the results are inco...

journal_title：Brain structure & function

authors： Li X,Papenberg G,Kalpouzos G,Bäckman L,Persson J

更新日期：2018-07-01 00:00:00

abstract：:This study investigates the mechanism of action of spadin, a putative fast-acting peptidic antidepressant (AD) and a functional blocker of the K(+) TREK-1 channel, in relation with the medial prefrontal cortex (mPFC)-dorsal raphé (DRN) serotonergic (5-HT) neurons connectivity. Spadin increased 5-HT neuron firing rate ...

journal_title：Brain structure & function

authors： Moha ou Maati H,Bourcier-Lucas C,Veyssiere J,Kanzari A,Heurteaux C,Borsotto M,Haddjeri N,Lucas G

更新日期：2016-01-01 00:00:00

abstract：:Childhood is defined by the development of cognitive abilities as well as brain growth and function. While prior neuroimaging studies have investigated early development fragmentally, we studied the typical development of functional network connectivity continuously from infancy to childhood (average of 24 months) in ...

journal_title：Brain structure & function

authors： Bruchhage MMK,Ngo GC,Schneider N,D'Sa V,Deoni SCL

更新日期：2020-03-01 00:00:00