Abstract：
:Cancer immunotherapy can induce long lasting responses in patients with metastatic cancers of a wide range of histologies. Broadening the clinical applicability of these treatments requires an improved understanding of the mechanisms limiting cancer immunotherapy. The interactions between the immune system and cancer cells are continuous, dynamic, and evolving from the initial establishment of a cancer cell to the development of metastatic disease, which is dependent on immune evasion. As the molecular mechanisms of resistance to immunotherapy are elucidated, actionable strategies to prevent or treat them may be derived to improve clinical outcomes for patients.
journal_name
Celljournal_title
Cellauthors
Sharma P,Hu-Lieskovan S,Wargo JA,Ribas Adoi
10.1016/j.cell.2017.01.017subject
Has Abstractpub_date
2017-02-09 00:00:00pages
707-723issue
4eissn
0092-8674issn
1097-4172pii
S0092-8674(17)30065-Xjournal_volume
168pub_type
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