Abstract：
:The Mre11-Rad50-Nbs1 (MRN) complex senses DNA double-strand breaks and recruits different repair pathway and checkpoint proteins to break foci. Two new studies (Williams et al., 2009; Lloyd et al., 2009) identify Nbs1 as a key factor in this process and reveal how an N-terminal protein recruitment module in Nbs1 binds to different response factors through shared phosphopeptide motifs.
journal_name
Celljournal_title
Cellauthors
Hopfner KPdoi
10.1016/j.cell.2009.09.017subject
Has Abstractpub_date
2009-10-02 00:00:00pages
25-7issue
1eissn
0092-8674issn
1097-4172pii
S0092-8674(09)01177-5journal_volume
139pub_type
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