A new shield for a cytokine storm.

Abstract:

:Highly virulent influenza virus infection results in excessive cytokine production, recruitment of leukocytes, and immune-mediated pulmonary injury. Teijaro et al. (2011) now demonstrate that sphingosine-1-phosphate receptor 1 ligands suppress all features of flu-inflicted pathological inflammation and place the endothelium at the center of this regulatory network.

journal_name

Cell

journal_title

Cell

authors

Iwasaki A,Medzhitov R

doi

10.1016/j.cell.2011.08.027

subject

Has Abstract

pub_date

2011-09-16 00:00:00

pages

861-2

issue

6

eissn

0092-8674

issn

1097-4172

pii

S0092-8674(11)00993-7

journal_volume

146

pub_type

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