Abstract:
:Highly virulent influenza virus infection results in excessive cytokine production, recruitment of leukocytes, and immune-mediated pulmonary injury. Teijaro et al. (2011) now demonstrate that sphingosine-1-phosphate receptor 1 ligands suppress all features of flu-inflicted pathological inflammation and place the endothelium at the center of this regulatory network.
journal_name
Celljournal_title
Cellauthors
Iwasaki A,Medzhitov Rdoi
10.1016/j.cell.2011.08.027subject
Has Abstractpub_date
2011-09-16 00:00:00pages
861-2issue
6eissn
0092-8674issn
1097-4172pii
S0092-8674(11)00993-7journal_volume
146pub_type
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