Abstract:
:In nongrowing microbes, proteome turnover is reduced and identification of newly synthesized, low-abundance proteins is challenging. Babin and colleagues recently utilized bio-orthogonal noncanonical amino acid tagging (BONCAT) to identify actively synthesized proteins in nongrowing Pseudomonas aeruginosa, discovering a regulator whose influences range from biofilm formation to secondary metabolism.
journal_name
Trends Microbioljournal_title
Trends in microbiologyauthors
Henry TC,Brynildsen MPdoi
10.1016/j.tim.2016.02.014subject
Has Abstractpub_date
2016-05-01 00:00:00pages
324-326issue
5eissn
0966-842Xissn
1878-4380pii
S0966-842X(16)00051-2journal_volume
24pub_type
杂志文章abstract::Cryptococcosis remains a significant cause of morbidity and mortality world-wide, particularly among AIDS patients. Yet, to date, there are no licensed vaccines clinically available to treat or prevent cryptococcosis. In this review, we provide a rationale to support continued investment in Cryptococcus vaccine resear...
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journal_title:Trends in microbiology
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abstract::Hospitals worldwide are facing an increasing incidence of hard-to-treat infections. Limiting infections and providing patients with optimal drug regimens require timely strain identification as well as virulence and drug-resistance profiling. Additionally, prophylactic interventions based on the identification of envi...
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journal_title:Trends in microbiology
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doi:10.1016/j.tim.2003.08.008
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journal_title:Trends in microbiology
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journal_title:Trends in microbiology
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