Tricorn-like proteases in bacteria.

abstract：:Adaptation of rhizobia to a symbiotic life style and synthesis of the nitrogen-fixing apparatus are coordinated with nodule development by the microaerobic conditions prevailing in the central nodule tissue. Sensing and transduction of the "low oxygen' signal involves similar regulatory elements in different rhizobia,...

journal_title：Trends in microbiology

authors： Fischer HM

更新日期：1996-08-01 00:00:00

abstract：:The polysaccharide-rich wall, which envelopes the fungal cell, is pivotal to the maintenance of cellular integrity and for the protection of the cell from external aggressors - such as environmental fluxes and during host infection. This review considers the commonalities in the composition of the wall across the fung...

journal_title：Trends in microbiology

authors： Geoghegan I,Steinberg G,Gurr S

更新日期：2017-12-01 00:00:00

abstract：:Numerous observations have established a crucial role for phagocytic cells in host resistance to Salmonella. Activated macrophages rely on a complex array of oxygen-dependent antimicrobial molecules to inhibit or kill intracellular Salmonella. An initial oxidative bactericidal phase, which is dependent on the respirat...

journal_title：Trends in microbiology

authors： Vazquez-Torres A,Fang FC

更新日期：2001-01-01 00:00:00

abstract：:Cancer progression begins when malignant cells colonize adjacent sites, and it is characterized by increasing tumor heterogeneity, invasion and dissemination of cancer cells. Clinically, progression is the most relevant stage in the natural history of cancers. A given virus is usually regarded as oncogenic because of ...

journal_title：Trends in microbiology

authors： Elgui de Oliveira D,Müller-Coan BG,Pagano JS

更新日期：2016-08-01 00:00:00

abstract：:The recent observation of a surge in human monkeypox in the Democratic Republic of the Congo (DRC) prompts the question of whether cessation of smallpox vaccination is driving the phenomenon, and if so, why is re-emergence not universal throughout the historic geographic range of the virus? Research addressing the vir...

journal_title：Trends in microbiology

authors： Reynolds MG,Damon IK

更新日期：2012-02-01 00:00:00

abstract：:Several times in this century, new and sometimes devastating diseases of cereal crops, caused by fungi in the genus Cochliobolus, have suddenly appeared. In many fungal diseases of plants the factors required for pathogenicity are unknown; in contrast, the key elements in each of several Cochliobolus diseases are know...

journal_title：Trends in microbiology

authors： Panaccione DG

更新日期：1993-04-01 00:00:00

abstract：:The Archaea include microorganisms growing in some of the most extreme environments on earth. Consequently, their cellular components are remarkably stable entities and have considerable potential in the biotechnology industry. Here, we review the structure of archaeal enzymes in the context of their ability to functi...

journal_title：Trends in microbiology

authors： Danson MJ,Hough DW

更新日期：1998-08-01 00:00:00

abstract：:A major goal in microbiology is to understand the processes by which bacteria successfully colonize host tissue. Although a wealth of studies focusing on pathogenic microorganisms has revealed much about the rare interactions that result in disease, far less is known about the regulation of the ubiquitous, long-term, ...

journal_title：Trends in microbiology

authors： Ruby EG,McFall-Ngai MJ

更新日期：1999-10-01 00:00:00

abstract：:A holistic approach to understanding the mechanisms by which stress influences the pathogenesis of infectious disease has resulted in the development of the field of microbial endocrinology. This transdisciplinary field represents the intersection of microbiology with mammalian endocrinology and neurophysiology, and i...

journal_title：Trends in microbiology

authors： Freestone PP,Sandrini SM,Haigh RD,Lyte M

更新日期：2008-02-01 00:00:00

abstract：:Bacteria and fungi in buildings exert an influence on the human microbiome through aerosol deposition, surface contact, and human and animal interactions. As the identities and functions of beneficial human microbes emerge, the consequences of building design, operation, and function must be understood to maintain the...

journal_title：Trends in microbiology

authors： Peccia J,Kwan SE

更新日期：2016-08-01 00:00:00

abstract：:HIV-1 evades antibody-mediated neutralization in many cunning ways. The recent structural characterization of a conserved neutralization epitope on the envelope glycoprotein complex (Env) provides clues to the vulnerabilities of the virus. We discuss these observations and explain their relevance for HIV-1 vaccine des...

journal_title：Trends in microbiology

authors： Eggink D,Melchers M,Sanders RW

更新日期：2007-07-01 00:00:00

abstract：:Intracellular pathogens customize the composition and function of the vacuoles they occupy, and can arrest or distort vacuolar maturation. In doubly infected cells, vacuoles that contain two different parasites can be used to test for exclusionary mechanisms, for expression of vacuolar phenotypes that permit or restri...

journal_title：Trends in microbiology

authors： Rabinovitch M,Veras PS

更新日期：1996-04-01 00:00:00

abstract：:Transcriptional regulation enables adaptation in bacteria. Typically, only a few transcriptional events are well understood, leaving many others unidentified. The recent genome-wide identification of transcription factor binding sites in Mycobacterium tuberculosis has changed this by deciphering a molecular road-map o...

journal_title：Trends in microbiology

authors： Baloni P,Chandra N

更新日期：2015-03-01 00:00:00

abstract：:To obtain iron from the host for growth, staphylococci have evolved sophisticated iron-scavenging systems including siderophores and a cell surface receptor for transferrin, the mammalian iron-transporting glycoprotein. The staphylococcal transferrin receptor has been identified as a member of a newly emerging family ...

journal_title：Trends in microbiology

authors： Modun B,Morrissey J,Williams P

更新日期：2000-05-01 00:00:00

abstract：:It is usually assumed that most prokaryotes, when given appropriate nutrients, can grow and divide in the absence of other cells of the same species. However, recent studies have suggested that, for growth, prokaryotes need to communicate with each other using signalling molecules, and a variety of 'eukaryotic' hormon...

journal_title：Trends in microbiology

authors： Kaprelyants AS,Kell DB

更新日期：1996-06-01 00:00:00

abstract：:Growing concerns about global climate change and energy dependence have led to an increased effort to reduce carbon emissions. A considerable reduction could be achieved by using biofuels from lignocellulosic biomass instead of fossil fuels. One major bottleneck of biofuel production from lignocellulose is the availab...

journal_title：Trends in microbiology

authors： Hess M

更新日期：2008-09-01 00:00:00

abstract：:Knockout mice with distinct gene deletions are valuable tools for in vivo analyses of the immune response against infectious agents. Studies of bacterial and protozoal infections have shown that antimicrobial immunity is generally defective in knockout mice. At one extreme, deletion of just one gene may completely com...

journal_title：Trends in microbiology

authors： Kaufmann SH,Ladel CH

更新日期：1994-07-01 00:00:00

abstract：:Invasive fungal infections are a major cause of mortality in immunocompromised patients. By using high-resolution sequencing, Zhai et al. provide insight into translocation of Candida strains from the gut mycobiota to the bloodstream of transplanted patients. Microbiota-driven diagnostic methods could rapidly emerge f...

journal_title：Trends in microbiology

authors： Papon N,Bougnoux ME,d'Enfert C

更新日期：2020-04-01 00:00:00

abstract：:Although it is commonly assumed that Darwin had nothing to say about microbes, he did in fact say quite a lot. He included microbes in his Beagle studies of the geographical distribution of organisms and used microscopic organisms as explicit exemplars of how adaptation did not imply increasing complexity. Darwin ofte...

journal_title：Trends in microbiology

authors： O'Malley MA

更新日期：2009-08-01 00:00:00

abstract：:The following pair of articles, the first by Gil Segal and Howard Shuman, and the second by James Kirby and Ralph Isberg (Trends Microbiol. 6, 256-258), explore the genetics and function of the icm/dot genes of Legionella pneumophila. This gene family is implicated in several aspects of virulence and appears to consti...

journal_title：Trends in microbiology

authors： Segal G,Shuman HA

更新日期：1998-07-01 00:00:00

abstract：:The global emergence of multidrug resistant Acinetobacter baumannii has reduced the number of clinically available antibiotics that retain activity against this pathogen. For this reason, the development of novel prevention and treatment strategies for infections caused by A. baumannii is necessary. Several studies ha...

journal_title：Trends in microbiology

authors： García-Quintanilla M,Pulido MR,López-Rojas R,Pachón J,McConnell MJ

更新日期：2013-03-01 00:00:00

abstract：:The genetic analysis of the large and complex herpesviruses has been a constant challenge to herpesvirologists. Elegant methods have been developed to produce mutants in infected cells that rely on the cellular recombination machinery. Bacterial artificial chromosomes (BACs), single copy F-factor-based plasmid vectors...

journal_title：Trends in microbiology

authors： Wagner M,Ruzsics Z,Koszinowski UH

更新日期：2002-07-01 00:00:00

abstract：:Recently, a new group of multicellular microorganisms was discovered, called 'cable bacteria', which are capable of generating and mediating electrical currents across centimetre-scale distances. By transporting electrons from cell to cell, cable bacteria can harvest electron donors and electron acceptors that are wid...

journal_title：Trends in microbiology

authors： Meysman FJR

更新日期：2018-05-01 00:00:00

abstract：:As plastic debris in the environment continues to increase, an emerging concern is the potential for microplastic to act as vectors for pathogen transport. With aquaculture the fastest growing food sector, and microplastic contamination of shellfish increasingly demonstrated, understanding any risk of pathogen transpo...

journal_title：Trends in microbiology

authors： Bowley J,Baker-Austin C,Porter A,Hartnell R,Lewis C

更新日期：2021-02-01 00:00:00

abstract：:Bacteria use type IV secretion systems (T4SS) to translocate macromolecular substrates destined for bacterial, plant or human target cells. The T4SS are medically important, contributing to virulence-gene spread, genome plasticity and the alteration of host cellular processes during infection. The T4SS are ancestrally...

journal_title：Trends in microbiology

authors： Ding Z,Atmakuri K,Christie PJ

更新日期：2003-11-01 00:00:00

abstract：:Strictly lytic phages have been consensually preferred for phage therapy purposes. In contrast, temperate phages have been avoided due to an inherent capacity to mediate transfer of genes between bacteria by specialized transduction - an event that may increase bacterial virulence, for example, by promoting antibiotic...

journal_title：Trends in microbiology

authors： Monteiro R,Pires DP,Costa AR,Azeredo J

更新日期：2019-04-01 00:00:00

abstract：:Two-component systems are characterized by phosphotransfer reactions involving histidine and aspartate residues in highly conserved signalling domains. Although the basic principles of signal transduction by these systems have been elucidated, several important aspects, such as their integration into more complex cell...

journal_title：Trends in microbiology

authors： Perraud AL,Weiss V,Gross R

更新日期：1999-03-01 00:00:00

abstract：:The human virome is the viral component of the microbiome. Its composition, and interindividual and temporal variability are not precisely known. Its impact on human health has received less attention than that of the bacterial microbiome, but is likely to be equally important, both in homeostasis and disease. Here we...

journal_title：Trends in microbiology

authors： Lecuit M,Eloit M

更新日期：2013-10-01 00:00:00

abstract：:The microbial surface components recognizing adhesive matrix molecules (MSCRAMMs) are a family of proteins that are defined by the presence of two adjacent IgG-like folded subdomains. These promote binding to ligands by mechanisms that involve major conformational changes exemplified by the binding to fibrinogen by th...

journal_title：Trends in microbiology

authors： Foster TJ

更新日期：2019-11-01 00:00:00

abstract：:Because the structure of the tobacco mosaic virus capsid protein is known, mutations that alter the phenotype of the virus-plant interaction can be correlated with structural changes in this protein. These mutations affect the disease symptoms caused by the virus and recognition of the virus by a plant resistance gene...

journal_title：Trends in microbiology

authors： Chapman S,Lindbeck AG,Dawson WO

更新日期：1993-10-01 00:00:00