Abstract:
PURPOSE:The aim of the study was to investigate whether incorrectly compensated eddy currents are the source of persistent X-nuclear spectroscopy and imaging artifacts, as well as methods to correct this. METHODS:Pulse-acquire spectra were collected for 1 H and X-nuclei (23 Na or 31 P) using the minimum TR permitted on a 3T clinical MRI system. Data were collected in 3 orientations (axial, sagittal, and coronal) with the spoiler gradient at the end of the TR applied along the slice direction for each. Modifications to system calibration files to tailor eddy current compensation for each X-nucleus were developed and applied, and data were compared with and without these corrections for: slice-selective MRS (for 23 Na and 31 P), 2D spiral trajectories (for 13 C), and 3D cones trajectories (for 23 Na). RESULTS:Line-shape distortions characteristic of eddy currents were demonstrated for X-nuclei, which were not seen for 1 H. The severity of these correlated with the amplitude of the eddy current frequency compensation term applied by the system along the axis of the applied spoiler gradient. A proposed correction to eddy current compensation, taking account of the gyromagnetic ratio, was shown to dramatically reduce these distortions. The same correction was also shown to improve data quality of non-Cartesian imaging (2D spiral and 3D cones trajectories). CONCLUSION:A simple adaptation of the default compensation for eddy currents was shown to eliminate a range of artifacts detected on X-nuclear spectroscopy and imaging.
journal_name
Magn Reson Medjournal_title
Magnetic resonance in medicineauthors
McLean MA,Hinks RS,Kaggie JD,Woitek R,Riemer F,Graves MJ,McIntyre DJO,Gallagher FA,Schulte RFdoi
10.1002/mrm.28607subject
Has Abstractpub_date
2020-12-04 00:00:00eissn
0740-3194issn
1522-2594pub_type
杂志文章abstract:PURPOSE:To investigate Shift Undersampling improves Parametric mapping Efficiency and Resolution (SUPER), a novel blockwise curve-fitting method for accelerating parametric mapping with very fast reconstruction. METHODS:SUPER uses interleaved k-space undersampling, which enables a blockwise decomposition of the otherw...
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abstract::This work aimed to investigate the effects of administering Gd-DTPA on the BOLD effect, and to determine the feasibility of using this approach to measure fractional changes in blood volume and blood oxygenation on neuronal activation during a visual paradigm. A linear relationship between cortical R(2)(*) and the int...
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abstract::MRS has considerable potential for the measurement of drug pharmacokinetics in vivo. In this study single- and double-resonance (31)P MRS was used to investigate the biodistribution, pharmacokinetics, and metabolism of ifosfamide following administration of 500 mg/kg ifosfamide in guinea pigs. (1)H-decoupling was foun...
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