Characterization of estrogen-receptor-targeted contrast agents in solution, breast cancer cells, and tumors in vivo.

abstract：:A novel center-out 3D trajectory for sampling magnetic resonance data is presented. The trajectory set is based on a single Fermat spiral waveform, which is substantially undersampled in the center of k-space. Multiple trajectories are combined in a "stacked cone" configuration to give very uniform sampling throughout...

journal_title：Magnetic resonance in medicine

authors： Pipe JG,Zwart NR,Aboussouan EA,Robison RK,Devaraj A,Johnson KO

更新日期：2011-11-01 00:00:00

abstract：:For clinical 31P MR spectroscopic imaging (MRSI) studies, where signal averaging is necessary, some improvement of sensitivity and spatial response function may be achieved by acquiring data over a spherical k-space volume and varying the number of averages acquired in proportion to the desired spatial filter. Eight d...

journal_title：Magnetic resonance in medicine

authors： Hugg JW,Maudsley AA,Weiner MW,Matson GB

更新日期：1996-09-01 00:00:00

abstract：:Homogeneous soft tissue, as regards its magnetic relaxation properties, is well-modeled by solutions of cross-linked protein (see Koenig and Brown, Prog. NMR Spectr. 22, 487 (1991)). Interactions at the solute-solvent interface alter the hydrodynamics of solvent water, and also couple the solute and solvent proton Zee...

journal_title：Magnetic resonance in medicine

authors： Koenig SH,Brown RD 3rd

更新日期：1993-12-01 00:00:00

abstract：:The investigation of flow behavior in coronary arteries is of great importance for an understanding of heart failure and heart regulation mechanisms. The purpose of the present study was to demonstrate that flow velocity can be quantified in the coronary arteries of the isolated rat heart with high-resolution phase co...

journal_title：Magnetic resonance in medicine

authors： Köhler S,Hiller KH,Jakob PM,Bauer WR,Haase A

更新日期：2003-09-01 00:00:00

abstract：:Variations in T(1ρ) with locking-field strength (T(1ρ) dispersion) may be used to estimate proton exchange rates. We developed a novel approach utilizing the second derivative of the dispersion curve to measure exchange in a model system of cross-linked polyacrylamide gels. These gels were varied in relative compositi...

journal_title：Magnetic resonance in medicine

authors： Cobb JG,Xie J,Gore JC

更新日期：2011-12-01 00:00:00

abstract：:A method is suggested whereby the shifted extracellular triple quantum filtered 23Na signal of an isolated organ is completely eliminated. The method is based on the long relaxation time of the triple quantum coherence and on its fast evolution rate. When the carrier frequency is set on top of the intracellular sodium...

journal_title：Magnetic resonance in medicine

authors： Navon G

更新日期：1993-10-01 00:00:00

abstract：:The equal-phase line (EPL) algorithm is proposed as a means of allowing rapid Fourier transform (FT) reconstruction of MR image data acquired on a non-Cartesian grid. The pixels on the image are grouped according to their positions. The pixels in a group have the same phase in the complex exponential function -exp[j2p...

journal_title：Magnetic resonance in medicine

authors： Qian Y,Lin J,Jin D

更新日期：2002-06-01 00:00:00

abstract：:Magnetization exchange effects between the matrix macromolecules (e. g., collagen and proteoglycan) and water were examined in normal, deuterated, and proteoglycan-depleted articular cartilage. Relaxation results (T(2), T(1rho), and T(1)) suggested that a four-site exchange scheme provided an accurate model for articu...

journal_title：Magnetic resonance in medicine

authors： Lattanzio PJ,Marshall KW,Damyanovich AZ,Peemoeller H

更新日期：2000-12-01 00:00:00

abstract：:In rapidly acquired gradient echo images, lipid regions usually appear as areas of high signal intensity. In 2D inflow angiograms processed by the maximum intensity projection algorithm, this high lipid signal may prevent angiographic visualization of some blood vessels. We present a new approach to suppress the lipid...

journal_title：Magnetic resonance in medicine

authors： Doyle M,Matsuda T,Pohost GM

更新日期：1991-09-01 00:00:00

abstract：:Pulsed arterial spin labeling (ASL) techniques provide a noninvasive method of obtaining qualitative and quantitative perfusion images with MRI. ASL techniques employ inversion recovery and/or saturation recovery to induce perfusion weighting, and thus the performance of these techniques is dependent on the slice prof...

journal_title：Magnetic resonance in medicine

authors： Keilholz-George SD,Knight-Scott J,Berr SS

更新日期：2001-07-01 00:00:00

abstract：:The combination of an in-plane B(1) sensitivity encoding (SENSE) technique with a simultaneous multiple-slice B(0) field step technique (multiple-acquisition micro B(0) array (MAMBA)) has produced high scan time reduction factors (R < or = 8). In this study, two slices were acquired simultaneously in combination with ...

journal_title：Magnetic resonance in medicine

authors： Paley MN,Lee KJ,Wild JM,Fichele S,Whitby EH,Wilkinson ID,Van Beek EJ,Griffiths PD

更新日期：2003-06-01 00:00:00

abstract：:A localized proton 2D double-quantum (DQ) spin-echo spectroscopy technique was implemented on 1.5 T clinical MRI scanners for the detection of gamma-aminobutyrate (GABA) in the brain. The 2D approach facilitates separation of peaks overlapping with GABA in 1D DQ-filtered (DQF) spectra. This technique was applied to fo...

journal_title：Magnetic resonance in medicine

authors： Wang ZJ,Bergqvist C,Hunter JV,Jin D,Wang DJ,Wehrli S,Zimmerman RA

更新日期：2003-04-01 00:00:00

abstract：:The purpose of this study was to evaluate an optimized multislice acquisition technique for oxygen-enhanced MRI of the lung using slice-selective inversion and refocusing pulses in combination with parallel imaging. An inversion recovery HASTE sequence was implemented with respiratory triggering to perform imaging in ...

journal_title：Magnetic resonance in medicine

authors： Dietrich O,Losert C,Attenberger U,Fasol U,Peller M,Nikolaou K,Reiser MF,Schoenberg SO

更新日期：2005-06-01 00:00:00

abstract：:Skeletal muscle triglycerides are markers for insulin resistance in type 2 diabetes. Recently, MR spectroscopy was adapted for in vivo measurement of triglycerides in animal models and for the characterization of new therapeutic approaches. Because of small MR spectroscopy voxel sizes used in skeletal muscles, surface...

journal_title：Magnetic resonance in medicine

authors： Neumaier M,Niessen HG,Kaulisch T,Stiller D

更新日期：2009-10-01 00:00:00

abstract：:The feasibility of MR subtraction imaging of lung ventilation using air against oxygen using a multiple inversion recovery half-Fourier single-shot turbo spin echo (MIR-HASTE) sequence was investigated. Eight healthy, nonsmoking volunteers (3 males, 5 females; from 27 to 48 years of age) were studied on a 1.5 T MR uni...

journal_title：Magnetic resonance in medicine

authors： Mai VM,Chen Q,Bankier AA,Edelman RR

更新日期：2000-06-01 00:00:00

abstract：:Levo-tetrahydropalmatine (l-THP) has shown significant promise in preclinical and clinical studies to treat drug addiction. Pharmacological MRI methods can elucidate the regional cerebral effects of l-THP, but there are potential confounds from the use of general anesthesia. To investigate the possible anesthetic-drug...

journal_title：Magnetic resonance in medicine

authors： Liu X,Li R,Yang Z,Hudetz AG,Li SJ

更新日期：2012-08-01 00:00:00

abstract：:A technique using hyperpolarized (HP) 3He to image the small airways of the lung by using moderate flip angles and a short scanning period during early inspiration is demonstrated. Flip angles (alpha) ranging from 10-90 degrees were used in guinea pig experiments with scanning during the entire inspiration period. A s...

journal_title：Magnetic resonance in medicine

authors： Chen XJ,Chawla MS,Hedlund LW,Möller HE,MacFall JR,Johnson GA

更新日期：1998-01-01 00:00:00

abstract：:The vascular space occupancy (VASO) method was recently proposed as a functional MRI (fMRI) method that is capable of detecting activation-related changes in blood volume (CBV), without the need for a blood-pool contrast agent. In the present work we introduce a new whole-brain VASO technique that is based on a parall...

journal_title：Magnetic resonance in medicine

authors： Poser BA,Norris DG

更新日期：2009-07-01 00:00:00

abstract：:The relaxivities (R-values) of the gadolinium diethylene triamine pentaacetic acid (Gd(DTPA)2-) ions in a series of skim-milk solutions at 0-40% milk concentrations were measured using NMR spectroscopy. The R-value was found to be approximately linearly proportional to the concentration of the solid component in the m...

journal_title：Magnetic resonance in medicine

authors： Zheng S,Xia Y

更新日期：2010-01-01 00:00:00

abstract：:A current limitation of many myocardial tag acquisitions employing SPAMM encoding is the relatively rapid loss of tag contrast over the cardiac cycle. Acquisition schemes that apply line tags produce prolonged tag contrast compared with directly excited grid tags. However, a grid-tag series can be generated by combini...

journal_title：Magnetic resonance in medicine

authors： Doyle M,Walsh EG,Foster RE,Pohost GM

更新日期：1997-05-01 00:00:00

abstract：PURPOSE:T2 -relaxation-under-spin-tagging (TRUST) is an MR technique for the non-invasive assessment of whole-brain cerebral oxygen extraction fraction (OEF), through measurement of the venous blood T2 relaxation time in the sagittal sinus. A key limitation of TRUST, however, is the lack of spatial specificity of the m...

journal_title：Magnetic resonance in medicine

authors： O'Brien C,Okell TW,Chiew M,Jezzard P

更新日期：2019-10-01 00:00:00

abstract：:High-resolution turbo spin echo (TSE) images have demonstrated important details of carotid artery morphology; however, it is evident that pulsatile blood and wall motion related to the cardiac cycle are still significant sources of image degradation. Although ECG gating can reduce artifacts due to cardiac-induced pul...

journal_title：Magnetic resonance in medicine

authors： Mendes J,Parker DL,Hulet J,Treiman GS,Kim SE

更新日期：2011-11-01 00:00:00

abstract：PURPOSE:Cardiac stimulation (CS) limits to gradient coil switching speed are difficult to measure in humans; instead, current regulatory guidelines (IEC 60601-2-33) are based on animal experiments and electric field-to-dB/dt conversion factors computed for a simple, homogeneous body model. We propose improvement to thi...

journal_title：Magnetic resonance in medicine

authors： Klein V,Davids M,Schad LR,Wald LL,Guérin B

更新日期：2021-02-01 00:00:00

abstract：PURPOSE:To develop the simultaneous acquisition of multiple voxels in localized MR spectroscopy (MRS) using sensitivity encoding, allowing reduced total scan time compared to conventional sequential single voxel (SV) acquisition methods. METHODS:Dual volume localization was used to simultaneously excite voxels in both...

journal_title：Magnetic resonance in medicine

authors： Boer VO,Klomp DW,Laterra J,Barker PB

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:To obtain multicontrast images including fat-suppressed contrast image, a novel multicontrast imaging method using an SSFP sequence with alternating RF flip angles is proposed. METHODS:The proposed method uses the balanced SSFP sequence with 2 flip angles. In general, the conventional balanced SSFP sequence ha...

journal_title：Magnetic resonance in medicine

authors： Kim J,Seo H,So S,Park H

更新日期：2018-10-01 00:00:00

abstract：:Aim of the study was to determine distribution and depletion patterns of intramyocellular lipids (IMCL) in leg muscles before and after two types of standardized endurance exercise. ¹H-magnetic resonance spectroscopic imaging was performed (1) in the thigh of eight-trained cyclists after exercising on an ergometer for...

journal_title：Magnetic resonance in medicine

authors： Vermathen P,Saillen P,Boss A,Zehnder M,Boesch C

更新日期：2012-11-01 00:00:00

abstract：:Chemical exchange saturation transfer (CEST), arterial spin labeling (ASL), and magnetization transfer contrast (MTC) methods generate different contrasts for MRI. However, they share many similarities in terms of pulse sequences and mechanistic principles. They all use RF pulse preparation schemes to label the longit...

journal_title：Magnetic resonance in medicine

authors： Knutsson L,Xu J,Ahlgren A,van Zijl PCM

更新日期：2018-10-01 00:00:00

abstract：:This study demonstrates the feasibility of applying free-breathing, cardiac-gated, susceptibility-weighted fast spin-echo imaging together with black blood preparation and navigator-gated respiratory motion compensation for anatomically accurate T2* mapping of the heart. First, T2* maps are presented for oil phantoms ...

journal_title：Magnetic resonance in medicine

authors： Heinrichs U,Utting JF,Frauenrath T,Hezel F,Krombach GA,Hodenius MA,Kozerke S,Niendorf T

更新日期：2009-09-01 00:00:00

abstract：:An in vitro study was performed to investigate the effects of B(o) inhomogeneity on magnetic resonance images of flow. Controlled inhomogeneity gradients (Gi) were applied and the magnitude of the artifacts produced was quantified for different echo delay times (TE). Both steady and pulsatile flows were examined. In t...

journal_title：Magnetic resonance in medicine

authors： Drangova M,Pelc NJ

更新日期：1996-01-01 00:00:00

abstract：PURPOSE:The correlation between glutamine metabolism and oncogene expression in cancers has led to a renewed interest in the role of glutamine in cancer cell survival. Hyperpolarized [5-(13) C]glutamine is evaluated as a potential biomarker for noninvasive metabolic measurements of drug response in prostate cancer cell...

journal_title：Magnetic resonance in medicine

authors： Canapè C,Catanzaro G,Terreno E,Karlsson M,Lerche MH,Jensen PR

更新日期：2015-06-01 00:00:00