Probing treatment response of glutaminolytic prostate cancer cells to natural drugs with hyperpolarized [5-(13) C]glutamine.

abstract：PURPOSE:Diffusion magnetic resonance imaging (MRI) microstructure imaging provides a unique noninvasive probe into tissue microstructure. The technique relies on biophysically motivated mathematical models, relating microscopic tissue features to the magnetic resonance (MR) signal. This work aims to determine which com...

journal_title：Magnetic resonance in medicine

authors： Ferizi U,Schneider T,Panagiotaki E,Nedjati-Gilani G,Zhang H,Wheeler-Kingshott CA,Alexander DC

更新日期：2014-12-01 00:00:00

abstract：:MRI evaluations of intramyocardial hemorrhage in acute infarction have relied on T(2) and T(2)(*) shortening only. We propose a more comprehensive evaluation of hemorrhagic infarction based on the concept that fluctuations in T(2) and T(1) relaxation in acute reperfused infarction will reflect transient edema and hemo...

journal_title：Magnetic resonance in medicine

authors： Foltz WD,Yang Y,Graham JJ,Detsky JS,Wright GA,Dick AJ

更新日期：2006-12-01 00:00:00

abstract：:Steady-state free precession (SSFP) methods have gained widespread recognition for their ability to provide fast scans at high signal-to-noise ratio. This paper demonstrates that such methods are also capable of reflecting functional information, particularly blood oxygenation state. It is well known that SSFP signals...

journal_title：Magnetic resonance in medicine

authors： Dharmakumar R,Hong J,Brittain JH,Plewes DB,Wright GA

更新日期：2005-03-01 00:00:00

abstract：:When using tracer kinetic modeling to analyze dynamic contrast-enhanced MRI (DCE-MRI) it is necessary to identify an appropriate arterial input function (AIF). The measured AIF is often poorly sampled in both clinical and preclinical MR systems due to the initial rapid increase in contrast agent concentration and the ...

journal_title：Magnetic resonance in medicine

authors： McGrath DM,Bradley DP,Tessier JL,Lacey T,Taylor CJ,Parker GJ

更新日期：2009-05-01 00:00:00

abstract：:Proton magnetic resonance spectroscopy ((1)H MRS) was used to determine brain temperature in healthy volunteers. Partially water-suppressed (1)H MRS data sets were acquired at 3T from four different gray matter (GM)/white matter (WM) volumes. Brain temperatures were determined from the chemical-shift difference betwee...

journal_title：Magnetic resonance in medicine

authors： Childs C,Hiltunen Y,Vidyasagar R,Kauppinen RA

更新日期：2007-01-01 00:00:00

abstract：:Optimization of experimental settings of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), like the contrast administration protocol, is of great importance for reliable quantification of the microcirculatory properties, such as the volume transfer-constant K(trans). Using system identification theory an...

journal_title：Magnetic resonance in medicine

authors： Aerts HJ,van Riel NA,Backes WH

更新日期：2008-05-01 00:00:00

abstract：:There is increasing interest in quantitative T(1) mapping techniques for a variety of applications. Several methods for T(1) quantification have been described. The acquisition of two spoiled gradient-echo data sets with different flip angles allows for the calculation of T(1) maps with a high spatial resolution and a...

journal_title：Magnetic resonance in medicine

authors： Preibisch C,Deichmann R

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:To evaluate proton density fat fraction (PDFF) and R2* as markers of bone marrow composition and structure in inflamed bone in patients with spondyloarthritis. METHODS:Phantoms containing fat, water, and trabecular bone were constructed with proton density fat fraction (PDFF) and bone mineral density (BMD) val...

journal_title：Magnetic resonance in medicine

authors： Bray TJP,Bainbridge A,Punwani S,Ioannou Y,Hall-Craggs MA

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:To assess the feasibility of using dissolved hyperpolarized xenon-129 (129 Xe) MRI to study renal physiology in humans at 3 T. METHODS:Using a flexible transceiver RF coil, dynamic and spatially resolved 129 Xe spectroscopy was performed in the abdomen after inhalation of hyperpolarized 129 Xe gas with 3 healt...

journal_title：Magnetic resonance in medicine

authors： Chacon-Caldera J,Maunder A,Rao M,Norquay G,Rodgers OI,Clemence M,Puddu C,Schad LR,Wild JM

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:To accelerate the acquisition of J-resolved proton magnetic resonance spectroscopic imaging (1 H-MRSI) data for high-resolution mapping of brain metabolites and neurotransmitters. METHODS:The proposed method used a subspace model to represent multidimensional spatiospectral functions, which significantly reduc...

journal_title：Magnetic resonance in medicine

authors： Tang L,Zhao Y,Li Y,Guo R,Clifford B,El Fakhri G,Ma C,Liang ZP,Luo J

更新日期：2021-01-01 00:00:00

abstract：:The clinical application of 3D proton spectroscopic imaging (3D SI) of the human prostate requires a robust suppression of periprostatic lipid signal contamination, minimal intervoxel signal contamination, and the shortest possible measurement time. In this work, a weighted elliptical sampling of k-space, combined wit...

journal_title：Magnetic resonance in medicine

authors： Scheenen TW,Klomp DW,Röll SA,Fütterer JJ,Barentsz JO,Heerschap A

更新日期：2004-07-01 00:00:00

abstract：:Detre et al. (Magn. Reson. Med. 23, 37-45 (1992)) and Zhang et al., (Magn. Reson. Med. 25, 362 (1992)) have recently demonstrated a technique for the measurement of regional cerebral blood flow (rCBF) based on the continuous saturation (or inversion) of the arterial blood supply to the brain in rats at 4.7 T. In the w...

journal_title：Magnetic resonance in medicine

authors： Walsh EG,Minematsu K,Leppo J,Moore SC

更新日期：1994-02-01 00:00:00

abstract：:Electron Spin Echo Envelope Modulation (ESEEM) data are reported for three gadolinium (III) chelates, Gd-EDTA, Gd-DTPA, and Gd-TTHA, in frozen D2O/CH3OD glasses. This series includes Gd-DTPA, an MRI contrast agent that is in clinical use. Three-pulse electron spin echo modulation patterns can be modeled to yield geome...

journal_title：Magnetic resonance in medicine

authors： Clarkson RB,Hwang JH,Belford RL

更新日期：1993-04-01 00:00:00

abstract：:In this study, the precision and accuracy of a new method for measuring axial rotations of the lumbar vertebrae, which are thought to be increased in patients with degenerative spinal instability, were estimated. A standard image registration algorithm involving a user-selected center of rotation was adapted for this ...

journal_title：Magnetic resonance in medicine

authors： Rogers BP,Haughton VM,Arfanakis K,Meyerand ME

更新日期：2002-12-01 00:00:00

abstract：:Since contrast in magnetic resonance imaging (MRI) is so sensitive to the magnetic relaxation rates of tissue protons, the use of paramagnetic ions to alter contrast in a tissue-specific fashion is an alluring prospect. The influence of these ions on the proton relaxation rates in homogeneous solutions is known to var...

journal_title：Magnetic resonance in medicine

authors： Koenig SH,Brown RD 3rd,Goldstein EJ,Burnett KR,Wolf GL

更新日期：1985-04-01 00:00:00

abstract：:Chemically-fixed nervous tissues are well-suited for high-resolution, time-intensive MRI acquisitions without motion artifacts, such as those required for brain atlas projects, but the aldehyde fixatives used may significantly alter tissue MRI properties. To test this hypothesis, this study characterized the impact of...

journal_title：Magnetic resonance in medicine

authors： Shepherd TM,Thelwall PE,Stanisz GJ,Blackband SJ

更新日期：2009-07-01 00:00:00

abstract：PURPOSE:To develop and validate a method for choosing the optimal two-dimensional CAIPIRINHA kernel for subtraction contrast-enhanced MR angiography (CE-MRA) and estimate the degree of image quality improvement versus that of some reference acceleration parameter set at R ≥ 8. METHODS:A metric based on patient-specifi...

journal_title：Magnetic resonance in medicine

authors： Weavers PT,Borisch EA,Riederer SJ

更新日期：2015-06-01 00:00:00

abstract：:Choline-containing compounds (CCCs) are elevated in breast cancer, and detected in vivo by the (1)H MRS total choline (tCho) resonance (3.25 ppm) and the (31)P MRS phosphomonoester (PME) resonance (3.8 ppm). Both the tCho and PME resonances decrease early after initiation of successful therapy. The single major compon...

journal_title：Magnetic resonance in medicine

authors： Morse DL,Raghunand N,Sadarangani P,Murthi S,Job C,Day S,Howison C,Gillies RJ

更新日期：2007-08-01 00:00:00

abstract：:Free induction decay signals are analyzed by fitting a model function directly in the time domain. No starting values are needed for linear model parameters, and omission of corrupted data points poses no problems. A significant gain of accuracy is achieved by imposing prior knowledge about the model parameters. ...

journal_title：Magnetic resonance in medicine

authors： van der Veen JW,de Beer R,Luyten PR,van Ormondt D

更新日期：1988-01-01 00:00:00

abstract：:Strong, extensive magnetic fringe fields are a significant problem with magnetic resonance imaging magnets. This is particularly acute with 4-T, whole-body research magnets. To date this problem has been addressed by restricting an extensive zone around the unshielded magnet or by placing external unsaturated iron shi...

journal_title：Magnetic resonance in medicine

authors： Huson FR,Bryan RN,MacKay WW,Herrick RC,Colvin J,Ford JJ,Pissanetzky S,Plishker GA,Rocha R,Schmidt W

更新日期：1993-01-01 00:00:00

abstract：PURPOSE:To develop a fast and accurate method for 3D T2 mapping of prostate cancer using undersampled acquisition and dictionary-based fitting. METHODS:3D high-resolution T2 -weighted images (0.9 × 0.9 × 3 mm3 ) were obtained with a multishot T2 -prepared balanced steady-state free precession (T2 -prep-bSSFP) acquisit...

journal_title：Magnetic resonance in medicine

authors： Roccia E,Vidya Shankar R,Neji R,Cruz G,Munoz C,Botnar R,Goh V,Prieto C,Dregely I

更新日期：2019-03-01 00:00:00

abstract：:Diffusion-weighted single voxel experiments conducted at b-values up to 1 x 10(4) smm-2 yielded biexponential signal attenuation curves for both normal and ischemic brain. The relative fractions of the rapidly and slowly decaying components (f1, f2) are f1 = 0.80 +/- 0.02, f2 = 0.17 +/- 0.02 in healthy adult rat brain...

journal_title：Magnetic resonance in medicine

authors： Niendorf T,Dijkhuizen RM,Norris DG,van Lookeren Campagne M,Nicolay K

更新日期：1996-12-01 00:00:00

abstract：:In this work a 3D fully balanced steady-state spin-echo sequence (bSSSE) was designed and implemented on a 3-Tesla whole-body MR scanner. In contrast to previously introduced nonbalanced SSSE (nbSSSE) sequences, bSSSE features fully rewound imaging gradients. Additionally, all phase encodings and the readout prephasin...

journal_title：Magnetic resonance in medicine

authors： Krug R,Han ET,Banerjee S,Majumdar S

更新日期：2006-11-01 00:00:00

abstract：:The selective multiple-quantum coherence transfer method has been applied to image polyunsaturated fatty acids (PUFA) distributions in human breast tissues in vivo for cancer detection, with complete suppression of the unwanted lipid and water signals in a single scan. The Cartesian k-space mapping of PUFA in vivo usi...

journal_title：Magnetic resonance in medicine

authors： Zhu H,Rubin D,He Q

更新日期：2012-01-01 00:00:00

abstract：:Generating flow-specific images (arteriograms, venograms) with optimal signal-to-noise ratios for time-resolved MR angiography is a conditional maximum problem, and its solutions are generalized matched filters. We have investigated six matched filters, corresponding to all possible combinations of three flow suppress...

journal_title：Magnetic resonance in medicine

authors： Wang Y,Weber DM,Korosec FR,Mistretta CA,Grist TM,Swan JS,Turski PA

更新日期：1993-11-01 00:00:00

abstract：:Dynamic contrast-enhanced MRI data in vertebral bone marrow (vBM) are currently analyzed with descriptive indices. The purpose of this study was to develop and evaluate a quantitative approach, considering the tissue composition of vBM. Therefore, a measurement of the water fraction, f(wat), and the precontrast relaxa...

journal_title：Magnetic resonance in medicine

authors： Biffar A,Sourbron S,Schmidt G,Ingrisch M,Dietrich O,Reiser MF,Baur-Melnyk A

更新日期：2010-07-01 00:00:00

abstract：:Phosphorus-31 nuclear magnetic resonance spectroscopy (31P NMR) was used to assess the temporal changes of high-energy phosphate metabolites in the region of acute myocardial ischemia of open-chest cats. Eight anesthetized cats were studied following ligation of the left anterior descending coronary artery. Creatine p...

journal_title：Magnetic resonance in medicine

authors： Stein PD,Goldstein S,Sabbah HN,Liu ZQ,Helpern JA,Ewing JR,Lakier JB,Chopp M,LaPenna WF,Welch KM

更新日期：1986-04-01 00:00:00

abstract：:The proton T(1) was measured at 132 μT in ex vivo prostate tissue specimens from radical prostatectomies of 35 patients with prostate cancer. Each patient provided two specimens. The NMR and MRI measurements involved proton repolarization, a field of typically 150 mT and detection of the 5.6-kHz signal with a supercon...

journal_title：Magnetic resonance in medicine

authors： Busch S,Hatridge M,Mößle M,Myers W,Wong T,Mück M,Chew K,Kuchinsky K,Simko J,Clarke J

更新日期：2012-04-01 00:00:00

abstract：:A deficit of fatty alcohol:NAD+ oxidoreductase complex (FAO) activity has been detected in patients with the Sjögren-Larsson syndrome (SLS). A moderate decrease in FAO activity has also been reported in heterozygote SLS subjects. Abnormal peaks were detected with proton magnetic resonance spectroscopy (1H-MRS) in homo...

journal_title：Magnetic resonance in medicine

authors： Kaminaga T,Mano T,Ono J,Kusuoka H,Nakamura H,Nishimura T

更新日期：2001-06-01 00:00:00

abstract：PURPOSE:Spectrally selective "prewinding" radiofrequency pulses can counteract B0 inhomogeneity in steady-state sequences, but can only prephase a limited range of off-resonance. We propose spectral-spatial small-tip angle prewinding pulses that increase the off-resonance bandwidth that can be successfully prephased by...

journal_title：Magnetic resonance in medicine

authors： Williams SN,Nielsen JF,Fessler JA,Noll DC

更新日期：2018-03-01 00:00:00